Human Analysis


Summary

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Job ID: FF:0011108
Number of target experiments: 3
Number of target CAGE peaks: 2925
Number of target CAGE peak regions: 1778
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 1778
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:11865-125B2 CD14+ monocytes - treated with lipopolysaccharide, donor1
FF:11875-125C3 CD14+ monocytes - treated with lipopolysaccharide, donor2
FF:11885-125D4 CD14+ monocytes - treated with lipopolysaccharide, donor3


Results

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Click column headers to sort by that column

Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 1432 346 1194 584 2944 0.0148 2196 0.011 50.628 44.376
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 855 923 593 1185 1256 0.00631 735 0.00369 60.794 42.969
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 1425 353 1197 581 2934 0.0147 2195 0.011 50.029 40.791
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 1618 160 1440 338 4640 0.0233 3744 0.0188 46.589 40.356
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 1519 259 1322 456 3642 0.0201 2870 0.0159 48.029 37.015
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 246 1532 103 1675 268 0.00188 107 0.000753 58.197 35.901
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 1398 380 1183 595 2850 0.0143 2222 0.0112 42.241 35.578
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 1513 265 1324 454 3438 0.0173 2627 0.0132 50.232 34.095
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 1433 345 1241 537 3027 0.0152 2361 0.0119 43.473 30.613
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 1562 216 1398 380 3958 0.0199 3063 0.0154 51.389 29.993
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 1340 438 1140 638 2656 0.0133 2088 0.0105 39.394 29.421
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 502 1276 320 1458 623 0.00438 370 0.0026 49.201 28.999
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 1664 114 1537 241 5309 0.0293 3996 0.0221 69.483 28.226
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 1231 547 1029 749 2305 0.0127 1877 0.0104 32.817 27.485
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 635 1143 446 1332 847 0.00468 551 0.00305 41.809 26.442
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 839 939 638 1140 1199 0.00602 848 0.00426 38.112 26.075
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 1053 725 851 927 1673 0.0084 1269 0.00638 35.880 25.738
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 574 1204 394 1384 739 0.00334 475 0.00215 36.311 25.689
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 820 958 633 1145 1208 0.00849 867 0.0061 43.365 22.964
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 1328 450 1165 613 3141 0.0331 2555 0.027 53.668 20.386
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 107 1671 40 1738 115 0.000809 40 0.000281 44.323 18.661
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 402 1376 270 1508 496 0.00249 311 0.00156 33.139 18.500
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 472 1306 337 1441 627 0.00472 394 0.00297 45.452 17.049
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 60 1718 15 1763 64 0.000482 15 0.000113 48.941 16.637
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 1507 271 1384 394 6181 0.0341 5891 0.0326 12.548 16.439
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 1659 119 1568 210 11909 0.0718 11243 0.0678 22.253 16.326
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 1575 203 1468 310 7196 0.0434 6614 0.0399 25.083 15.453
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 853 925 702 1076 1257 0.00631 1025 0.00515 22.889 15.452
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 813 965 666 1112 1149 0.00577 907 0.00456 25.386 14.912
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 617 1161 480 1298 817 0.00616 631 0.00476 28.661 14.768
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 278 1500 179 1599 325 0.00229 192 0.00135 35.879 14.687
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 1556 222 1449 329 6583 0.0397 6100 0.0368 21.620 14.678
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 1509 269 1398 380 4082 0.0205 3438 0.0173 34.887 13.971
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 1764 14 1726 52 11154 0.0392 8652 0.0304 72.068 13.676
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 1018 760 879 899 1721 0.00692 1409 0.00567 23.487 13.266
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 138 1640 73 1705 148 0.00112 78 0.000588 30.656 12.948
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 1113 665 978 800 2123 0.0117 1688 0.00933 35.166 12.914
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 982 796 845 933 1655 0.00914 1339 0.0074 28.646 12.901
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 1329 449 1207 571 2603 0.0131 2152 0.0108 30.791 12.546
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 1525 253 1427 351 8166 0.0451 7696 0.0425 17.938 11.849
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 280 1498 193 1585 312 0.00188 207 0.00125 25.242 11.476
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 151 1627 87 1691 158 0.00119 93 0.000701 26.064 11.446
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 396 1382 295 1483 456 0.00252 328 0.00181 23.402 11.419
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 583 1195 468 1310 881 0.00752 807 0.0069 10.685 11.192
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 592 1186 477 1301 801 0.00322 585 0.00235 25.223 11.101
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 367 1411 271 1507 411 0.00248 325 0.00196 16.483 11.040
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 1509 269 1417 361 4850 0.0195 5018 0.0202 -6.922 10.370
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 87 1691 42 1736 95 0.000859 42 0.00038 34.653 10.285
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 1624 154 1550 228 8335 0.046 7894 0.0436 16.609 10.207
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 480 1298 378 1400 577 0.00377 440 0.00287 23.513 10.200
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 1705 73 1650 128 6729 0.0372 6245 0.0345 20.472 10.119
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 423 1355 327 1451 498 0.003 391 0.00236 18.704 9.980
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 1671 107 1608 170 7963 0.032 8811 0.0354 -26.204 9.916
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 1291 487 1184 594 3325 0.0167 3326 0.0167 -0.190 9.805
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 324 1454 239 1539 367 0.00221 281 0.00169 17.730 9.796
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 221 1557 151 1627 246 0.00148 163 0.000983 22.480 9.493
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 1649 129 1584 194 5795 0.0291 4873 0.0245 42.110 9.314
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 1074 704 964 814 1956 0.00982 1933 0.00972 1.558 9.122
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 1184 594 1077 701 2165 0.012 1875 0.0104 22.213 9.117
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 1542 236 1462 316 6605 0.0265 7100 0.0285 -17.028 8.991
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 1571 207 1496 282 7157 0.0288 7731 0.0311 -18.935 8.780
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 1053 725 946 832 1979 0.0129 1841 0.012 11.548 8.684
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 1137 641 1034 744 1953 0.0108 1759 0.00973 15.307 8.399
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 1396 382 1306 472 3230 0.0162 2789 0.014 26.460 8.351
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 144 1634 92 1686 151 0.00114 96 0.000724 21.700 8.170
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 1234 544 1137 641 2764 0.0111 2857 0.0115 -5.060 8.056
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 1168 610 1070 708 2357 0.0107 2169 0.00981 12.061 7.883
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 1219 559 1123 655 2265 0.0125 1963 0.0109 22.613 7.853
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 1263 515 1169 609 2880 0.0159 2723 0.0151 9.923 7.834
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 808 970 709 1069 1203 0.00906 1021 0.0077 22.044 7.719
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 1395 383 1310 468 3956 0.0159 4411 0.0177 -19.683 7.647
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 1200 578 1105 673 2194 0.00882 1836 0.00738 23.619 7.642
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 1610 168 1547 231 4749 0.0262 4336 0.024 20.887 7.633
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 716 1062 620 1158 942 0.0071 861 0.00649 10.636 7.601
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 1495 283 1419 359 5178 0.0208 5636 0.0227 -17.605 7.538
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 1611 167 1549 229 6414 0.0322 5788 0.0291 26.220 7.482
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 1107 671 1011 767 1768 0.00888 1567 0.00788 16.020 7.447
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 1449 329 1370 408 5003 0.0201 5120 0.0206 -4.821 7.385
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 1678 100 1628 150 6977 0.035 5956 0.0299 42.281 7.362
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 183 1595 128 1650 200 0.00141 139 0.000978 19.319 7.325
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 1017 761 922 856 1718 0.0104 1581 0.00954 11.886 7.167
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 1312 466 1226 552 3253 0.0163 3567 0.0179 -16.910 7.127
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 422 1356 344 1434 494 0.00248 402 0.00202 14.466 7.086
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 1211 567 1122 656 2214 0.0122 2037 0.0113 12.965 6.966
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 360 1418 288 1490 408 0.00287 325 0.00229 17.184 6.895
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 495 1283 414 1364 602 0.00423 485 0.00341 19.840 6.863
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 847 931 756 1022 1351 0.00814 1213 0.00732 13.680 6.719
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 1720 58 1683 95 12060 0.0424 13051 0.0459 -23.712 6.565
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 1557 221 1494 284 8021 0.0604 7600 0.0573 19.005 6.547
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 1648 130 1597 181 5847 0.0323 5483 0.0303 16.370 6.520
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 1142 636 1057 721 2144 0.0151 1817 0.0128 28.760 6.285
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 684 1094 600 1178 871 0.00481 810 0.00448 7.049 6.279
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 1201 577 1118 660 2248 0.0113 2081 0.0105 11.526 6.245
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 160 1618 114 1664 166 0.00117 119 0.000837 16.080 6.078
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 1044 734 960 818 1745 0.00964 1583 0.00875 13.460 5.991
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 581 1197 503 1275 832 0.00501 712 0.00429 15.535 5.988
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 1403 375 1332 446 3526 0.0195 3081 0.017 26.673 5.929
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 188 1590 140 1638 232 0.0021 197 0.00178 10.534 5.747
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 1013 765 932 846 1819 0.0119 1706 0.0111 9.805 5.651
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 261 1517 206 1572 298 0.00314 228 0.00241 21.205 5.614
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 1551 227 1494 284 4506 0.0226 4354 0.0219 7.209 5.602
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 1421 357 1354 424 4730 0.019 5400 0.0217 -26.217 5.588
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 63 1715 36 1742 63 0.000538 36 0.000308 18.512 5.555
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 399 1379 334 1444 518 0.00312 438 0.00264 13.195 5.528
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 1539 239 1482 296 5874 0.0295 6425 0.0323 -22.277 5.452
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 185 1593 139 1639 202 0.00132 148 0.000967 15.963 5.443
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 476 1302 408 1370 603 0.00515 497 0.00425 19.567 5.370
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 122 1656 85 1693 129 0.000777 89 0.000537 14.648 5.321
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 116 1662 80 1698 119 0.000717 81 0.000489 14.586 5.303
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 139 1639 100 1678 148 0.00104 107 0.000753 14.790 5.222
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 1549 229 1495 283 4650 0.0163 4150 0.0146 20.553 5.176
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 487 1291 421 1357 659 0.00496 610 0.0046 7.625 5.083
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 1075 703 1002 776 2077 0.0104 1943 0.00977 9.553 4.942
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 1435 343 1375 403 4358 0.0263 4331 0.0261 1.272 4.889
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 1649 129 1608 170 5545 0.0362 5258 0.0344 14.324 4.858
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 446 1332 384 1394 561 0.00366 517 0.00338 6.921 4.856
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 925 853 852 926 1648 0.0108 1519 0.00993 11.884 4.845
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 28 1750 12 1766 29 0.000262 12 0.000109 20.770 4.829
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 1351 427 1289 489 6314 0.0349 6119 0.0338 8.217 4.641
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 844 934 774 1004 1382 0.00555 1295 0.00521 6.775 4.599
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 21 1757 8 1770 21 0.000148 8 5.63e-05 17.137 4.442
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 1218 560 1154 624 2616 0.0131 2548 0.0128 4.168 4.384
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 542 1236 481 1297 682 0.00343 600 0.00302 10.536 4.335
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 79 1699 53 1725 79 0.000555 54 0.00038 12.689 4.334
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 287 1491 239 1539 333 0.00251 281 0.00212 11.968 4.330
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 1446 332 1392 386 3846 0.0155 3775 0.0152 3.164 4.313
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 1596 182 1553 225 7208 0.029 7639 0.0307 -14.344 4.311
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 733 1045 668 1110 1075 0.00756 1015 0.00714 6.979 4.267
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 815 963 750 1028 1100 0.00718 1086 0.0071 1.447 4.180
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 277 1501 231 1547 313 0.00173 249 0.00138 13.409 4.168
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 1778 0 1772 6 14529 0.0657 14162 0.0641 9.293 4.163
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 1583 195 1540 238 6980 0.028 8148 0.0328 -37.388 4.162
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 61 1717 39 1739 63 0.000443 40 0.000281 13.566 4.115
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 250 1528 207 1571 266 0.00174 230 0.0015 8.514 4.039
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 1358 420 1303 475 3743 0.0188 4285 0.0215 -26.613 3.993
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 232 1546 191 1587 265 0.00173 209 0.00137 13.924 3.959
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 1483 295 1435 343 3595 0.0199 3264 0.018 19.244 3.914
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 561 1217 504 1274 689 0.00346 606 0.00305 10.612 3.904
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 1635 143 1599 179 9042 0.0454 9333 0.0469 -9.980 3.895
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 1438 340 1388 390 5129 0.0206 5853 0.0235 -27.237 3.866
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 217 1561 178 1600 239 0.00144 191 0.00115 11.989 3.852
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 1143 635 1084 694 2022 0.0102 1830 0.0092 14.152 3.808
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 1754 24 1737 41 20404 0.102 19094 0.096 31.188 3.808
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 728 1050 669 1109 1027 0.00774 916 0.00691 14.160 3.763
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 97 1681 71 1707 102 0.000871 74 0.000632 13.380 3.733
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 570 1208 515 1263 743 0.0056 649 0.00489 14.244 3.705
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 1284 494 1230 548 2326 0.0105 2191 0.00991 8.588 3.673
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 1510 268 1466 312 6582 0.0231 6948 0.0244 -11.920 3.671
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 1484 294 1439 339 5447 0.0219 6124 0.0246 -24.930 3.618
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 1289 489 1236 542 2856 0.0143 2665 0.0134 11.654 3.601
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 840 938 782 996 1275 0.00961 1268 0.00956 0.662 3.594
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 105 1673 79 1699 108 0.000651 82 0.000495 9.907 3.538
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 1626 152 1592 186 5657 0.0284 5285 0.0266 16.225 3.523
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 854 924 797 981 1513 0.0106 1448 0.0102 6.316 3.512
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 1652 126 1621 157 8796 0.0309 9463 0.0333 -18.634 3.459
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 929 849 874 904 1557 0.0109 1419 0.00999 13.666 3.351
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 1313 465 1264 514 4010 0.0161 4770 0.0192 -31.560 3.331
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 139 1639 112 1666 144 0.00108 116 0.000875 10.028 3.118
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 1547 231 1511 267 5103 0.0205 5336 0.0215 -9.269 3.093
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 1722 56 1702 76 15339 0.0847 14239 0.0787 31.545 3.084
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 924 854 873 905 1544 0.00853 1426 0.00788 10.307 3.063
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 161 1617 133 1645 170 0.0012 146 0.00103 7.389 2.996
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 1247 531 1201 577 3084 0.0124 3186 0.0128 -5.261 2.964
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 300 1478 264 1514 367 0.00258 314 0.00221 11.144 2.918
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 1141 637 1094 684 2224 0.0123 2171 0.012 3.679 2.897
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 76 1702 57 1721 77 0.000464 57 0.000344 9.137 2.888
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 1352 426 1310 468 4783 0.0144 5425 0.0164 -21.653 2.874
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 1541 237 1507 271 5831 0.0234 6677 0.0268 -29.845 2.867
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 1229 549 1184 594 3404 0.0154 3734 0.0169 -16.469 2.864
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 1448 330 1410 368 4430 0.0178 4395 0.0177 1.368 2.828
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 1493 285 1457 321 4331 0.0239 4130 0.0228 10.333 2.826
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 1525 253 1491 287 5450 0.0219 5770 0.0232 -12.210 2.789
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 199 1579 170 1608 215 0.0014 177 0.00116 10.256 2.784
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 1076 702 1030 748 2293 0.00921 2386 0.00959 -5.512 2.776
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 1777 1 1772 6 16684 0.0503 17485 0.0527 -15.480 2.776
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 1619 159 1591 187 4990 0.0201 4820 0.0194 6.846 2.761
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 1045 733 999 779 1805 0.00997 1738 0.00961 5.251 2.758
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 1223 555 1181 597 3156 0.0159 3734 0.0188 -30.328 2.647
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 9 1769 3 1775 9 8.14e-05 3 2.71e-05 14.619 2.622
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 1427 351 1391 387 3262 0.0131 3077 0.0124 9.372 2.605
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 20 1758 11 1767 20 0.000211 12 0.000127 10.537 2.605
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 934 844 890 888 1547 0.00777 1502 0.00755 3.592 2.596
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 1390 388 1353 425 4368 0.0176 4724 0.019 -14.929 2.587
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 25 1753 15 1763 26 0.000222 15 0.000128 11.664 2.580
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 478 1300 440 1338 647 0.00487 634 0.00478 1.928 2.550
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 736 1042 695 1083 1055 0.00424 1059 0.00426 -0.420 2.457
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 1603 175 1577 201 4714 0.026 4441 0.0246 13.589 2.449
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 1585 193 1558 220 6542 0.023 6630 0.0233 -3.051 2.445
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 205 1573 179 1599 223 0.00134 196 0.00118 6.637 2.426
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 1561 217 1533 245 5412 0.0272 5215 0.0262 8.570 2.419
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 1693 85 1675 103 11801 0.0652 11843 0.0655 -1.593 2.290
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 45 1733 33 1745 46 0.000393 34 0.000291 8.445 2.265
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 1678 100 1659 119 11041 0.0555 10488 0.0527 17.298 2.258
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 38 1740 27 1751 39 0.000294 27 0.000204 8.903 2.252
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 1113 665 1076 702 2611 0.0144 2886 0.016 -17.241 2.232
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 1777 1 1773 5 15457 0.0699 16051 0.0726 -14.885 2.215
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 1656 122 1636 142 6357 0.0223 6309 0.0222 1.461 2.188
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 236 1542 211 1567 263 0.00172 228 0.00149 8.312 2.186
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 603 1175 568 1210 758 0.00381 718 0.00361 4.661 2.185
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 68 1710 54 1724 68 0.000581 56 0.000478 6.573 2.159
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 1300 478 1267 511 4067 0.0204 4753 0.0239 -31.998 2.158
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 1247 531 1214 564 2748 0.0138 3103 0.0156 -20.435 2.099
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 418 1360 388 1390 514 0.00258 454 0.00228 8.856 2.098
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 900 878 866 912 1932 0.0107 2229 0.0123 -21.103 2.009
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 396 1382 368 1410 460 0.00231 454 0.00228 0.835 2.001
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 50 1728 39 1739 51 0.000359 40 0.000281 6.468 1.956
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 85 1693 71 1707 85 0.000726 72 0.000615 6.277 1.941
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 1446 332 1420 358 3673 0.0184 3502 0.0176 9.078 1.934
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 86 1692 72 1706 90 0.000768 72 0.000615 8.707 1.931
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 81 1697 68 1710 83 0.000709 68 0.000581 7.460 1.848
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 1330 448 1303 475 4382 0.0198 5033 0.0228 -27.995 1.833
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 1062 716 1032 746 1950 0.00979 1922 0.00966 1.925 1.823
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 99 1679 85 1693 100 0.000753 90 0.000679 4.042 1.817
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 354 1424 330 1448 408 0.00225 397 0.00219 1.777 1.809
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 155 1623 138 1640 169 0.0011 151 0.000987 5.239 1.804
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 835 943 805 973 1423 0.00715 1455 0.00731 -2.753 1.804
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 1613 165 1595 183 5885 0.0296 5675 0.0285 8.765 1.780
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 1427 351 1403 375 3320 0.015 3282 0.0148 1.877 1.776
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 397 1381 373 1405 514 0.00284 482 0.00266 4.780 1.746
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 1110 668 1082 696 1916 0.0144 1798 0.0136 10.726 1.738
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 18 1760 12 1766 18 0.000154 12 0.000103 7.094 1.716
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 788 990 760 1018 1217 0.00917 1208 0.00911 0.906 1.712
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 19 1759 13 1765 19 0.000153 13 0.000105 6.609 1.674
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 1157 621 1131 647 2004 0.0101 1944 0.00977 4.219 1.657
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 171 1607 155 1623 192 0.00135 183 0.00129 2.444 1.652
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 263 1515 244 1534 288 0.0026 272 0.00246 4.062 1.640
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 31 1747 24 1754 31 0.000234 24 0.000181 5.493 1.572
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 1491 287 1473 305 4283 0.0172 4657 0.0187 -15.785 1.505
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 416 1362 396 1382 491 0.0037 454 0.00342 6.669 1.496
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 25 1753 19 1759 25 0.000163 19 0.000124 4.918 1.495
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 1084 694 1061 717 2034 0.0102 2019 0.0101 0.955 1.490
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 178 1600 164 1614 193 0.00116 180 0.00109 3.313 1.470
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 1397 381 1378 400 3066 0.0154 2957 0.0149 6.257 1.457
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 19 1759 14 1764 20 0.000151 14 0.000106 6.164 1.417
*SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 2 1776 0 1778 2 1.61e-05 0 0 NA 1.387
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 695 1083 675 1103 923 0.00556 976 0.00589 -5.975 1.361
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 271 1507 257 1521 321 0.00242 291 0.00219 6.761 1.310
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 1655 123 1645 133 11452 0.0805 11024 0.0776 15.580 1.274
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 81 1697 73 1705 81 0.00057 81 0.00057 -0.039 1.265
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 1211 567 1194 584 3239 0.0146 3540 0.016 -15.427 1.262
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 1162 616 1145 633 2983 0.012 3516 0.0141 -25.721 1.248
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 29 1749 24 1754 34 0.000307 33 0.000299 0.700 1.237
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 513 1265 498 1280 656 0.00461 639 0.0045 2.448 1.199
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 19 1759 15 1763 19 0.000162 18 0.000154 0.930 1.194
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 1069 709 1053 725 2158 0.00867 2232 0.00897 -4.549 1.191
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 740 1038 724 1054 1026 0.00773 1056 0.00796 -3.683 1.189
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 991 787 975 803 1903 0.0105 2165 0.012 -18.896 1.183
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 182 1596 173 1605 193 0.00116 195 0.00118 -0.541 1.117
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 378 1400 367 1411 436 0.00241 419 0.00232 2.701 1.078
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 843 935 831 947 1448 0.00873 1491 0.00899 -3.974 1.033
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 1568 210 1560 218 5889 0.0325 5958 0.0329 -3.203 1.024
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 219 1559 211 1567 251 0.00202 237 0.00191 3.587 1.023
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 832 946 821 957 1238 0.00684 1200 0.00663 3.562 0.999
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 948 830 937 841 1884 0.0114 1852 0.0112 2.478 0.998
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 43 1735 39 1739 44 0.000354 40 0.000322 2.491 0.997
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 512 1266 502 1276 645 0.00421 695 0.00454 -6.925 0.997
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 1653 125 1647 131 5450 0.0274 5503 0.0277 -2.463 0.987
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 1498 280 1490 288 3877 0.0214 3546 0.0196 18.466 0.983
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 341 1437 334 1444 418 0.00273 421 0.00275 -0.588 0.919
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 1235 543 1227 551 3124 0.0126 3610 0.0145 -23.164 0.917
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 1003 775 995 783 1649 0.00994 1724 0.0104 -6.395 0.900
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 1770 8 1768 10 9986 0.0451 10620 0.048 -19.139 0.899
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 881 897 873 905 1323 0.00664 1387 0.00697 -5.540 0.898
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 1342 436 1335 443 2778 0.0126 2788 0.0126 -0.689 0.897
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 46 1732 43 1735 50 0.000402 47 0.000378 1.712 0.879
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 13 1765 11 1767 13 9.14e-05 12 8.44e-05 1.032 0.870
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 1018 760 1011 767 1604 0.00644 1622 0.00652 -1.354 0.869
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 53 1725 50 1728 53 0.000373 57 0.000401 -2.020 0.866
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 1337 441 1331 447 3511 0.0123 3563 0.0125 -2.436 0.860
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 288 1490 283 1495 338 0.00187 399 0.00221 -10.191 0.850
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 1704 74 1701 77 9709 0.0536 9283 0.0513 14.813 0.835
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 193 1585 189 1589 209 0.00178 207 0.00177 0.522 0.831
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 1295 483 1290 488 2742 0.0124 2854 0.0129 -6.447 0.821
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 109 1669 106 1672 109 0.000766 122 0.000858 -4.446 0.812
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 115 1663 112 1666 125 0.000942 118 0.00089 2.454 0.809
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 35 1743 33 1745 35 0.000211 33 0.000199 1.166 0.796
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 199 1579 196 1582 229 0.0023 226 0.00227 0.837 0.782
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 361 1417 358 1420 420 0.00338 476 0.00383 -10.352 0.762
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 407 1371 404 1374 530 0.00293 592 0.00327 -8.526 0.759
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 1023 755 1020 758 1985 0.011 2142 0.0118 -11.428 0.749
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 125 1653 123 1655 130 0.00104 138 0.00111 -2.769 0.747
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 292 1486 290 1488 329 0.00231 323 0.00227 1.194 0.730
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 19 1759 18 1760 19 0.000162 18 0.000154 0.930 0.693
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 25 1753 24 1754 25 0.000201 25 0.000201 -0.039 0.693
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 1778 0 1777 1 24327 0.0977 24625 0.099 -5.994 0.693
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 1639 139 1638 140 7244 0.04 7468 0.0413 -8.989 0.693
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 80 1698 79 1699 83 0.000667 82 0.000659 0.402 0.693
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 1120 658 1121 657 2518 0.0114 2967 0.0134 -25.009 0.639
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 1508 270 1509 269 3696 0.0149 3829 0.0154 -6.254 0.621
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 1711 67 1712 66 6600 0.0331 6985 0.0351 -15.020 0.562
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 1404 374 1408 370 3566 0.0161 3852 0.0174 -14.079 0.542
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 1199 579 1204 574 3439 0.0173 4035 0.0203 -30.113 0.536
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 1738 40 1739 39 7887 0.0317 8007 0.0322 -4.041 0.528
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 1690 88 1692 86 10164 0.0357 10401 0.0366 -6.461 0.524
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 1506 272 1510 268 5215 0.0183 5525 0.0194 -11.284 0.524
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 778 1000 784 994 1093 0.00823 1113 0.00839 -2.428 0.522
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 1130 648 1136 642 2666 0.0134 3048 0.0153 -22.171 0.517
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 1770 8 1770 8 20253 0.061 19359 0.0584 15.960 0.513
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 8 1770 8 1770 8 7.23e-05 8 7.24e-05 -0.050 0.513
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 1219 559 1225 553 3228 0.013 3619 0.0146 -18.638 0.511
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 190 1588 194 1584 200 0.001 201 0.00101 -0.266 0.500
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 1191 587 1198 580 2275 0.0114 2267 0.0114 0.422 0.490
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 729 1049 737 1041 949 0.00524 983 0.00543 -3.685 0.477
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 413 1365 420 1358 516 0.00181 491 0.00173 2.936 0.471
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 17 1761 18 1760 17 0.000128 18 0.000136 -0.955 0.458
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 475 1303 483 1295 619 0.00373 677 0.00408 -7.805 0.457
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 1539 239 1545 233 3769 0.0208 3807 0.021 -2.215 0.454
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 1669 109 1673 105 5438 0.0219 5943 0.0239 -18.908 0.450
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 1172 606 1181 597 3302 0.0182 3944 0.0218 -34.422 0.449
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 415 1363 423 1355 557 0.00392 513 0.00361 7.212 0.448
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 202 1576 208 1570 225 0.00181 224 0.0018 0.216 0.441
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 932 846 943 835 1554 0.00468 1668 0.00503 -6.929 0.421
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 806 972 817 961 1442 0.00797 1543 0.00853 -8.659 0.420
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 985 793 996 782 1897 0.00762 1981 0.00797 -5.452 0.420
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 310 1468 319 1459 360 0.00325 368 0.00333 -1.836 0.401
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 1068 710 1080 698 2582 0.0156 3007 0.0181 -27.225 0.397
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 672 1106 684 1094 1089 0.00492 1217 0.00551 -11.114 0.396
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 894 884 907 871 1848 0.00835 2142 0.00969 -19.247 0.385
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 2 1776 2 1776 2 1.61e-05 2 1.61e-05 -0.092 0.375
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 2 1776 2 1776 3 3.01e-05 2 2.01e-05 3.078 0.375
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 48 1730 52 1726 52 0.00047 55 0.000498 -1.755 0.365
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 759 1019 773 1005 1080 0.00651 1096 0.00661 -1.766 0.365
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 1044 734 1058 720 1635 0.00739 1821 0.00824 -13.222 0.363
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 7 1771 8 1770 8 6.83e-05 8 6.84e-05 -0.051 0.361
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 16 1762 18 1760 16 0.000113 18 0.000127 -1.806 0.361
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 1087 691 1101 677 2305 0.0174 2540 0.0191 -18.372 0.360
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 1139 639 1153 625 1842 0.00925 2083 0.0105 -16.888 0.356
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 14 1764 16 1762 14 0.000113 18 0.000145 -3.812 0.345
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 794 984 810 968 1122 0.00451 1195 0.00481 -6.061 0.333
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 54 1724 59 1719 60 0.000482 64 0.000515 -2.038 0.333
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 72 1706 78 1700 72 0.000506 88 0.000619 -6.421 0.328
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 1093 685 1109 669 2378 0.0119 2868 0.0144 -29.260 0.327
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 897 881 914 864 1331 0.00735 1420 0.00785 -7.955 0.319
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 48 1730 53 1725 49 0.000345 54 0.00038 -2.583 0.318
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 581 1197 597 1181 927 0.00512 1087 0.00601 -16.222 0.318
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 130 1648 139 1639 147 0.00118 146 0.00117 0.286 0.305
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 668 1110 687 1091 865 0.00565 966 0.00631 -11.835 0.281
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 870 908 890 888 1257 0.00631 1394 0.00701 -11.730 0.275
E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 3 1775 4 1774 3 2.41e-05 4 3.22e-05 -2.068 0.257
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 1701 77 1709 69 6266 0.0283 7166 0.0324 -32.601 0.253
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 538 1240 558 1220 836 0.00462 1002 0.00554 -17.515 0.252
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 640 1138 661 1117 918 0.00692 942 0.0071 -3.128 0.251
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 377 1401 395 1383 468 0.00259 505 0.00279 -5.527 0.248
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 417 1361 436 1342 532 0.00294 556 0.00307 -3.442 0.243
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 464 1314 484 1294 639 0.00321 729 0.00366 -10.624 0.239
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 6 1772 8 1770 6 6.03e-05 8 8.04e-05 -3.210 0.238
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 162 1616 175 1603 177 0.00116 196 0.00128 -4.941 0.238
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 415 1363 435 1343 513 0.00309 518 0.00312 -0.825 0.229
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 341 1437 360 1418 443 0.00289 519 0.00339 -12.110 0.223
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 195 1583 210 1568 209 0.00199 230 0.0022 -6.095 0.222
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 516 1262 538 1240 717 0.00468 814 0.00532 -12.366 0.222
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 707 1071 731 1047 960 0.00482 1130 0.00568 -16.113 0.219
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 5 1773 7 1771 5 3.77e-05 7 5.28e-05 -2.983 0.215
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 824 954 849 929 1232 0.00619 1364 0.00686 -11.426 0.212
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 1034 744 1059 719 2176 0.00874 2715 0.0109 -29.519 0.208
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 48 1730 56 1722 50 0.000427 59 0.000504 -4.869 0.205
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 419 1359 441 1337 518 0.00286 597 0.0033 -10.802 0.203
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 1203 575 1227 551 2031 0.0102 2331 0.0117 -19.872 0.203
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 1341 437 1363 415 2744 0.011 2858 0.0115 -6.177 0.202
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 814 964 840 938 1233 0.00929 1280 0.00965 -5.214 0.201
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 68 1710 78 1700 74 0.000632 87 0.000743 -5.787 0.194
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 178 1600 194 1584 195 0.00137 217 0.00153 -5.639 0.193
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 1673 105 1685 93 6254 0.0188 6955 0.021 -20.952 0.187
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 191 1587 208 1570 204 0.00123 233 0.00141 -6.631 0.186
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 1484 294 1504 274 3479 0.0175 3636 0.0183 -8.448 0.184
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 63 1715 73 1705 65 0.000555 74 0.000632 -4.353 0.184
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 1182 596 1208 570 2456 0.0123 3222 0.0162 -43.141 0.183
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 39 1739 47 1731 40 0.000281 49 0.000345 -4.848 0.178
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 1320 458 1345 433 2531 0.0127 2807 0.0141 -16.709 0.171
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 1129 649 1157 621 1903 0.00956 2051 0.0103 -10.491 0.168
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 1734 44 1742 36 7520 0.0378 7815 0.0393 -10.969 0.168
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 737 1041 766 1012 1132 0.00569 1285 0.00646 -13.622 0.168
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 317 1461 340 1438 344 0.0019 387 0.00214 -7.309 0.162
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 889 889 920 858 1493 0.00675 1596 0.00722 -7.851 0.153
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 1662 116 1677 101 5403 0.0217 6118 0.0246 -26.333 0.141
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 8 1770 12 1766 8 7.23e-05 12 0.000109 -4.942 0.140
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 531 1247 562 1216 705 0.0039 837 0.00463 -15.236 0.131
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 676 1102 709 1069 908 0.00456 915 0.0046 -0.807 0.129
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 1590 188 1610 168 4384 0.022 4738 0.0238 -16.615 0.128
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 625 1153 658 1120 814 0.00531 871 0.00569 -7.062 0.125
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 1575 203 1596 182 4999 0.0201 5336 0.0215 -13.339 0.125
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 38 1740 48 1730 40 0.000342 54 0.000461 -7.892 0.122
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 921 857 956 822 1962 0.0118 2449 0.0148 -34.459 0.120
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 1121 657 1155 623 2559 0.0129 3440 0.0173 -48.036 0.117
BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 2 1776 4 1774 2 1.71e-05 4 3.42e-05 -4.188 0.116
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 2 1776 4 1774 2 1.71e-05 4 3.42e-05 -4.188 0.116
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 272 1506 298 1480 320 0.00193 368 0.00222 -8.730 0.115
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 847 931 883 895 1482 0.0112 2134 0.0161 -55.221 0.113
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 461 1317 493 1285 639 0.00353 754 0.00417 -13.985 0.112
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 55 1723 68 1710 56 0.00045 70 0.000563 -6.732 0.105
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 55 1723 68 1710 57 0.000458 68 0.000547 -5.374 0.105
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 991 787 1028 750 2223 0.00782 2548 0.00896 -17.205 0.104
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 238 1540 264 1514 269 0.00176 340 0.00222 -13.949 0.102
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 527 1251 562 1216 646 0.00389 731 0.00441 -10.983 0.100
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 751 1027 789 989 1440 0.00796 1729 0.00956 -23.257 0.098
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 343 1435 374 1404 422 0.00212 499 0.00251 -10.968 0.095
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 239 1539 266 1512 278 0.00209 341 0.00257 -13.284 0.094
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 949 829 988 790 1438 0.00794 1582 0.00875 -12.155 0.093
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 857 921 897 881 1394 0.007 1499 0.00753 -8.698 0.088
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 649 1129 688 1090 856 0.0043 904 0.00454 -5.132 0.087
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 261 1517 290 1488 286 0.00172 328 0.00198 -8.092 0.086
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 425 1353 460 1318 532 0.00267 582 0.00293 -6.623 0.085
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 452 1326 488 1290 550 0.00304 590 0.00326 -5.533 0.083
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 442 1336 479 1299 550 0.00276 615 0.00309 -8.361 0.076
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 90 1688 109 1669 96 0.000675 122 0.000858 -8.850 0.075
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 1637 141 1659 119 4903 0.0197 5404 0.0217 -19.636 0.072
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 485 1293 524 1254 583 0.00322 665 0.00368 -10.629 0.071
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 168 1610 194 1584 186 0.00131 239 0.00168 -12.884 0.069
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 1504 274 1535 243 4669 0.0188 5243 0.0211 -22.805 0.066
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 1088 690 1131 647 1753 0.0088 1918 0.00964 -12.071 0.066
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 383 1395 420 1358 512 0.00309 612 0.00369 -14.091 0.066
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 31 1747 43 1735 32 0.000273 47 0.000402 -9.058 0.065
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 21 1757 31 1747 21 0.000179 31 0.000265 -7.442 0.064
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 13 1765 21 1757 13 0.000104 22 0.000177 -7.713 0.062
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 5 1773 10 1768 5 5.27e-05 13 0.000137 -10.207 0.061
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 1172 606 1215 563 2276 0.0126 2701 0.0149 -27.445 0.060
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 558 1220 601 1177 879 0.0053 1047 0.00631 -18.121 0.059
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 65 1713 83 1695 70 0.000633 85 0.000769 -6.944 0.057
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 620 1158 665 1113 936 0.0047 1103 0.00554 -16.020 0.056
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 1143 635 1188 590 1927 0.00968 2224 0.0112 -20.132 0.054
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 415 1363 456 1322 501 0.00252 578 0.00291 -10.200 0.052
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 14 1764 23 1755 14 0.000113 23 0.000185 -7.544 0.050
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 923 855 972 806 1707 0.00857 2217 0.0111 -34.543 0.048
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 43 1735 59 1719 44 0.000265 61 0.000368 -7.577 0.045
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 832 946 882 896 1149 0.00577 1294 0.0065 -12.870 0.044
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 474 1304 519 1259 611 0.00307 738 0.00371 -14.873 0.044
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 1278 500 1323 455 2364 0.0095 2685 0.0108 -17.720 0.042
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 646 1132 696 1082 807 0.00405 904 0.00454 -10.295 0.040
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 874 904 928 850 1380 0.00693 1408 0.00708 -2.457 0.033
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 166 1612 199 1579 186 0.000934 244 0.00123 -11.790 0.031
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 432 1346 481 1297 555 0.00279 672 0.00338 -14.357 0.028
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 903 875 960 818 1333 0.0067 1545 0.00777 -17.210 0.026
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 527 1251 580 1198 752 0.00415 839 0.00464 -10.056 0.026
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 510 1268 563 1215 765 0.00461 956 0.00577 -21.535 0.025
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 164 1614 199 1579 174 0.00105 214 0.00129 -9.521 0.023
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 671 1107 729 1049 876 0.00572 1026 0.0067 -17.023 0.022
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 66 1712 90 1688 68 0.000546 95 0.000764 -11.122 0.020
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 1141 637 1199 579 1917 0.00963 2212 0.0111 -20.050 0.019
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 940 838 1001 777 1764 0.00975 2211 0.0122 -31.828 0.019
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 327 1451 376 1402 384 0.00328 484 0.00414 -18.844 0.018
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 1001 777 1062 716 1988 0.00998 2628 0.0132 -39.848 0.018
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 165 1613 203 1575 186 0.00159 218 0.00186 -8.993 0.016
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 1174 604 1233 545 2001 0.0111 2335 0.0129 -23.185 0.016
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 1175 603 1235 543 2069 0.0114 2268 0.0125 -14.059 0.014
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 810 968 876 902 1106 0.00444 1378 0.00554 -20.855 0.012
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 144 1634 182 1596 158 0.00111 232 0.00163 -18.236 0.012
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 1504 274 1551 227 3782 0.0171 3985 0.018 -9.872 0.010
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 926 852 994 784 1366 0.00892 1529 0.00999 -15.205 0.010
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 155 1623 196 1582 173 0.00122 251 0.00177 -18.482 0.009
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 236 1542 285 1493 272 0.00137 363 0.00182 -15.164 0.009
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 134 1644 175 1603 146 0.00125 187 0.0016 -12.417 0.006
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 158 1620 206 1572 188 0.00132 258 0.00182 -16.367 0.003
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 355 1423 424 1354 415 0.00313 490 0.00369 -13.209 0.002
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 432 1346 509 1269 504 0.00253 631 0.00317 -16.071 0.002
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 469 1309 549 1229 559 0.00365 693 0.00453 -18.462 0.001
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 460 1318 541 1237 548 0.00275 694 0.00349 -17.616 0.001
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 398 1380 476 1302 481 0.00242 602 0.00303 -15.675 0.001
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 1592 186 1644 134 4543 0.0228 5115 0.0257 -25.780 0.001
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 709 1069 800 978 1111 0.00837 1460 0.011 -35.669 0.001
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 1165 613 1252 526 2028 0.00815 2384 0.00959 -20.818 0.001
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 1450 328 1519 259 3268 0.0164 3549 0.0178 -15.185 0.001
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 542 1236 633 1145 655 0.00329 865 0.00435 -22.693 0.001
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 812 966 916 862 1172 0.00589 1437 0.00722 -22.269 0.000
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 300 1478 382 1396 332 0.00167 477 0.0024 -21.069 0.000
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 53 1725 96 1682 53 0.000426 101 0.000812 -19.147 0.000
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 307 1471 394 1384 350 0.00334 466 0.00445 -23.540 0.000
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 34 1744 70 1708 35 0.000299 70 0.000598 -17.286 0.000
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 1375 403 1466 312 4378 0.0308 4872 0.0343 -27.130 0.000
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 84 1694 140 1638 86 0.000518 144 0.000869 -16.786 0.000
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 548 1230 666 1112 683 0.00652 942 0.009 -37.037 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 636 1142 760 1018 814 0.00491 1047 0.00631 -25.100 0.000
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 1252 526 1375 403 2339 0.0094 2870 0.0115 -28.301 0.000
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 429 1349 556 1222 602 0.00423 856 0.00602 -32.653 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 451 1327 582 1196 594 0.00358 945 0.0057 -39.734 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 431 1347 572 1206 508 0.00306 767 0.00463 -32.534 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 275 1503 408 1370 311 0.00187 528 0.00318 -32.818 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 386 1392 541 1237 485 0.00292 818 0.00493 -40.495 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 41 1737 113 1665 41 0.000309 118 0.00089 -27.498 0.000

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HOMER results

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