Human Analysis


Summary

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Job ID: FF:0100741
Number of target experiments: 6
Number of target CAGE peaks: 1725
Number of target CAGE peak regions: 1179
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 1179
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:10429-106D6 acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL
FF:10455-106G5 acute lymphoblastic leukemia (B-ALL) cell line:BALL-1
FF:10464-106H5 acute lymphoblastic leukemia (T-ALL) cell line:Jurkat
FF:10534-107G3 acute lymphoblastic leukemia (B-ALL) cell line:NALM-6
FF:10718-109I7 biphenotypic B myelomonocytic leukemia cell line:MV-4-11
FF:10777-110G3 NK T cell leukemia cell line:KHYG-1


Results

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Click column headers to sort by that column

Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 1021 158 847 332 2286 0.0197 1704 0.0147 47.068 42.334
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 943 236 766 413 1878 0.0147 1332 0.0104 47.521 36.272
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 946 233 771 408 1894 0.0148 1343 0.0105 47.762 35.767
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 1076 103 945 234 2904 0.0227 2224 0.0174 45.957 32.890
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 999 180 845 334 2200 0.0172 1576 0.0123 49.977 32.442
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 571 608 392 787 755 0.0059 489 0.00382 38.085 30.878
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 827 352 651 528 1433 0.0123 1078 0.00927 35.995 30.846
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 891 288 722 457 1705 0.0133 1247 0.00975 41.181 30.814
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 693 486 526 653 1032 0.00807 757 0.00592 31.672 26.340
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 949 230 804 375 1932 0.0151 1443 0.0113 40.904 26.079
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 918 261 772 407 1844 0.0144 1351 0.0106 42.606 24.923
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 1023 156 906 273 2413 0.0189 1842 0.0144 42.339 22.136
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 411 768 277 902 515 0.00443 337 0.0029 32.180 20.979
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 988 191 886 293 3763 0.0324 3303 0.0284 26.883 15.931
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 1102 77 1028 151 3335 0.0287 2620 0.0225 46.813 15.726
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 973 206 875 304 4966 0.0427 4300 0.037 34.270 14.365
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 838 341 730 449 1958 0.0321 1535 0.0252 50.063 13.423
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 1036 143 956 223 4480 0.042 3886 0.0365 33.572 12.626
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 1025 154 943 236 4120 0.0386 3590 0.0337 31.119 12.605
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 149 1030 85 1094 206 0.0029 117 0.00165 34.912 11.954
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 156 1023 91 1088 165 0.00181 96 0.00105 26.339 11.783
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 536 643 432 747 697 0.00545 560 0.00438 18.322 11.738
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 1130 49 1079 100 4462 0.0384 3843 0.033 33.625 11.530
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 545 634 442 737 751 0.00587 611 0.00478 17.928 11.494
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 1104 75 1046 133 6794 0.0531 5896 0.0461 37.804 11.057
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 459 720 364 815 605 0.00473 458 0.00358 21.735 10.634
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 753 426 656 523 1198 0.00936 974 0.00761 22.754 10.504
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 835 344 742 437 2143 0.0167 1867 0.0146 20.312 10.482
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 811 368 717 462 1435 0.0112 1175 0.00919 24.065 10.415
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 1057 122 991 188 5105 0.0439 4511 0.0388 29.862 10.248
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 1007 172 933 246 4833 0.0567 4210 0.0494 38.077 10.126
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 1163 16 1133 46 12637 0.0988 11090 0.0867 48.524 9.531
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 971 208 900 279 2698 0.0232 2359 0.0203 23.345 8.614
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 848 331 769 410 3811 0.0328 3478 0.0299 18.965 8.226
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 1169 10 1146 33 7114 0.0389 5920 0.0324 41.686 8.214
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 301 878 230 949 387 0.00454 272 0.00319 27.024 8.197
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 1113 66 1070 109 3798 0.0386 3282 0.0334 32.978 7.682
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 366 813 296 883 527 0.007 460 0.00611 12.893 7.159
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 994 185 934 245 2514 0.0216 2085 0.0179 31.402 7.112
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 1075 104 1027 152 3205 0.0276 2784 0.0239 26.741 7.003
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 309 870 245 934 377 0.00413 284 0.00311 20.656 6.815
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 1080 99 1034 145 7263 0.0681 6381 0.0599 39.378 6.771
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 781 398 710 469 1459 0.0114 1225 0.00958 21.212 6.577
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 363 816 297 882 436 0.00341 355 0.00278 13.590 6.553
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 636 543 566 613 1140 0.0116 994 0.0101 16.750 6.104
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 152 1027 108 1071 160 0.00163 113 0.00115 15.927 6.070
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 336 843 276 903 503 0.0059 369 0.00433 27.049 5.886
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 144 1035 102 1077 159 0.00249 114 0.00178 18.842 5.868
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 197 982 149 1030 208 0.00195 158 0.00148 13.767 5.781
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 1105 74 1069 110 3678 0.0287 3690 0.0288 -0.680 5.646
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 1093 86 1055 124 6978 0.0764 6299 0.0689 33.101 5.606
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 1138 41 1110 69 9491 0.0816 8344 0.0718 43.149 5.508
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 653 526 588 591 1074 0.0101 941 0.00883 15.056 5.486
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 475 704 412 767 676 0.00792 538 0.00631 23.088 5.475
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 387 792 328 851 483 0.00566 400 0.00469 16.085 5.367
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 296 883 243 936 357 0.00279 277 0.00217 15.194 5.228
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 547 632 485 694 843 0.00988 687 0.00806 23.114 5.174
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 207 972 162 1017 225 0.00211 178 0.00167 12.191 5.071
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 980 199 932 247 2565 0.02 2481 0.0194 5.346 5.006
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 924 255 872 307 2690 0.0252 2471 0.0232 15.398 4.987
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 347 832 294 885 429 0.00469 360 0.00394 13.609 4.825
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 642 537 583 596 1129 0.00971 983 0.00845 15.480 4.780
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 122 1057 88 1091 128 0.0012 98 0.000919 10.479 4.776
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 56 1123 33 1146 59 0.000553 33 0.00031 15.650 4.769
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 534 645 476 703 904 0.00989 793 0.00868 14.783 4.729
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 252 927 206 973 289 0.00271 234 0.0022 12.446 4.652
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 449 730 394 785 617 0.00579 530 0.00497 13.098 4.590
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 1086 93 1054 125 3341 0.0209 3297 0.0206 2.150 4.293
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 934 245 889 290 2438 0.021 2126 0.0183 22.610 4.185
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 1032 147 996 183 2638 0.0186 2484 0.0175 9.314 3.973
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 21 1158 9 1170 21 0.00023 9 9.85e-05 14.919 3.876
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 224 955 186 993 248 0.00271 214 0.00234 8.684 3.810
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 509 670 460 719 790 0.00864 688 0.00753 14.577 3.805
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 188 991 153 1026 214 0.00251 177 0.00208 10.760 3.764
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 856 323 811 368 1540 0.0108 1398 0.00984 11.419 3.762
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 630 549 582 597 1210 0.0123 1062 0.0108 16.431 3.635
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 40 1139 24 1155 41 0.000449 24 0.000263 12.953 3.567
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 1090 89 1063 116 6021 0.0471 6567 0.0513 -21.933 3.555
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 302 877 262 917 376 0.00264 319 0.00224 9.563 3.512
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 1128 51 1107 72 6209 0.0534 5519 0.0475 31.501 3.448
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 122 1057 95 1084 128 0.0013 99 0.00101 10.491 3.445
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 440 739 396 783 557 0.00479 492 0.00423 9.715 3.440
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 134 1045 106 1073 150 0.00141 117 0.0011 10.551 3.415
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 97 1082 73 1106 104 0.00114 77 0.000843 11.494 3.399
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 21 1158 10 1169 21 0.000295 10 0.000141 14.717 3.368
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 1096 83 1071 108 5100 0.0319 6051 0.0378 -35.301 3.355
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 773 406 730 449 1314 0.0154 1175 0.0138 15.779 3.325
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 1075 104 1048 131 3053 0.0239 3044 0.0238 0.480 3.301
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 1176 3 1169 10 6718 0.0473 6774 0.0477 -2.150 3.086
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 504 675 463 716 695 0.0076 641 0.00702 7.981 3.058
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 811 368 772 407 1477 0.0115 1383 0.0108 8.005 3.040
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 1094 85 1071 108 3251 0.0203 3311 0.0207 -3.020 3.014
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 89 1090 68 1111 92 0.00108 72 0.000844 9.109 3.013
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 29 1150 17 1162 30 0.000328 17 0.000186 11.761 2.991
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 53 1126 37 1142 54 0.000717 37 0.000492 11.499 2.933
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 267 912 234 945 314 0.00368 266 0.00312 11.393 2.927
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 145 1034 120 1059 158 0.00148 130 0.00122 8.490 2.835
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 56 1123 40 1139 57 0.000757 40 0.000532 11.059 2.834
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 470 709 433 746 614 0.0072 560 0.00657 8.840 2.755
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 488 691 451 728 730 0.00856 694 0.00814 5.286 2.734
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 820 359 785 394 1878 0.0117 1960 0.0123 -5.303 2.710
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 999 180 971 208 2610 0.0224 2467 0.0212 9.610 2.706
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 396 783 361 818 501 0.00587 452 0.0053 8.925 2.706
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 307 872 275 904 348 0.00354 332 0.00337 3.149 2.669
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 726 453 690 489 1255 0.0108 1260 0.0108 -0.500 2.651
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 1065 114 1042 137 4093 0.032 4069 0.0318 1.161 2.647
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 73 1106 56 1123 79 0.000741 59 0.000553 8.997 2.610
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 73 1106 56 1123 75 0.000879 56 0.000657 9.812 2.610
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 103 1076 84 1095 112 0.0014 93 0.00116 7.863 2.465
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 7 1172 2 1177 7 9.85e-05 2 2.81e-05 14.914 2.414
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 497 682 464 715 855 0.00735 810 0.00697 5.235 2.409
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 970 209 944 235 3111 0.0195 3060 0.0191 2.594 2.365
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 611 568 579 600 885 0.00761 878 0.00755 0.759 2.294
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 11 1168 5 1174 12 0.000131 5 5.47e-05 11.651 2.261
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 769 410 739 440 1574 0.0111 1464 0.0103 8.638 2.237
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 637 542 606 573 1066 0.01 954 0.00895 12.588 2.226
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 740 439 710 469 1403 0.0154 1221 0.0134 19.585 2.209
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 89 1090 73 1106 97 0.00114 81 0.00095 6.866 2.199
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 1081 98 1063 116 3622 0.0283 3461 0.0271 8.728 2.194
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 176 1003 155 1024 189 0.00266 172 0.00242 5.484 2.138
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 288 891 263 916 371 0.00435 359 0.00421 2.435 2.109
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 1080 99 1063 116 3969 0.031 3875 0.0303 4.802 2.070
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 562 617 535 644 1018 0.0103 905 0.0092 13.576 1.955
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 1103 76 1089 90 4450 0.0348 3675 0.0287 40.970 1.913
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 174 1005 156 1023 192 0.00225 177 0.00208 4.350 1.855
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 29 1150 21 1158 29 0.00034 21 0.000246 6.729 1.842
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 1018 161 1000 179 3005 0.0164 2965 0.0162 1.923 1.836
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 281 898 260 919 343 0.00456 314 0.00417 6.738 1.810
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 17 1162 11 1168 17 0.000199 11 0.000129 6.964 1.766
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 205 974 187 992 230 0.0018 208 0.00163 4.806 1.751
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 327 852 306 873 388 0.00425 357 0.00391 6.127 1.735
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 667 512 644 535 1127 0.0123 1053 0.0115 8.550 1.710
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 558 621 535 644 906 0.00566 919 0.00575 -1.241 1.705
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 1131 48 1121 58 8203 0.0449 8926 0.0488 -20.817 1.684
SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 4 1175 1 1178 4 5e-05 1 1.25e-05 11.873 1.675
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 405 774 384 795 516 0.00403 502 0.00392 1.957 1.654
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 571 608 549 630 1081 0.0101 1006 0.00944 8.200 1.644
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 1076 103 1063 116 3209 0.0251 3199 0.025 0.523 1.623
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 140 1039 126 1053 156 0.00171 136 0.00149 6.400 1.616
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 646 533 625 554 1388 0.00976 1483 0.0104 -7.469 1.588
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 151 1028 137 1042 163 0.00166 156 0.00159 2.001 1.576
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 216 963 200 979 254 0.00318 232 0.0029 5.763 1.566
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 561 618 541 638 800 0.00688 769 0.00661 3.694 1.530
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 34 1145 27 1152 36 0.000506 28 0.000394 6.388 1.522
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 207 972 192 987 234 0.00201 211 0.00181 5.235 1.510
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 35 1144 28 1151 35 0.000465 28 0.000372 5.427 1.506
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 1125 54 1116 63 4144 0.0194 4155 0.0195 -0.461 1.496
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 1177 2 1174 5 12607 0.0591 11657 0.0547 22.102 1.486
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 131 1048 119 1060 151 0.00165 137 0.0015 4.457 1.466
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 55 1124 47 1132 56 0.000744 48 0.000638 4.738 1.430
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 30 1149 24 1155 30 0.000422 25 0.000352 4.215 1.403
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 846 333 830 349 1840 0.0144 1857 0.0145 -1.291 1.395
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 1154 25 1148 31 5131 0.0401 4873 0.0381 11.863 1.388
*BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 2 1177 0 1179 2 2.66e-05 0 0 NA 1.387
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 853 326 838 341 1580 0.00988 1703 0.0107 -8.505 1.343
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 68 1111 60 1119 73 0.000856 64 0.00075 4.335 1.338
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 69 1110 61 1118 72 0.000844 61 0.000715 5.433 1.332
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 1006 173 994 185 4241 0.0232 4893 0.0268 -25.040 1.332
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 904 275 890 289 1902 0.0119 1852 0.0116 3.274 1.327
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 292 887 278 901 354 0.00194 335 0.00183 2.728 1.325
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 1134 45 1127 52 4445 0.0347 4379 0.0342 3.159 1.320
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 963 216 951 228 2393 0.0187 2464 0.0193 -4.605 1.269
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 187 992 176 1003 225 0.00246 203 0.00222 5.762 1.258
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 67 1112 60 1119 69 0.000755 62 0.000679 3.304 1.231
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 710 469 696 483 1180 0.00738 1225 0.00766 -3.677 1.229
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 664 515 650 529 1053 0.00741 1072 0.00754 -1.774 1.221
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 1016 163 1006 173 2966 0.0232 3018 0.0236 -3.071 1.211
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 19 1160 15 1164 19 0.000267 20 0.000281 -0.979 1.196
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 9 1170 6 1173 9 0.000148 6 9.85e-05 5.565 1.194
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 755 424 742 437 1720 0.0202 1745 0.0205 -2.381 1.191
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 144 1035 135 1044 156 0.00146 145 0.00136 3.145 1.187
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 40 1139 35 1144 41 0.000449 36 0.000394 3.091 1.141
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 520 659 508 671 738 0.00865 721 0.00845 2.434 1.127
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 707 472 696 483 1372 0.0107 1359 0.0106 1.091 1.086
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 485 694 474 705 807 0.00568 903 0.00635 -9.639 1.086
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 333 846 323 856 415 0.00357 388 0.00334 4.531 1.080
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 758 421 748 431 1394 0.012 1281 0.011 10.497 1.050
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 713 466 703 476 1166 0.01 1132 0.00973 3.338 1.043
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 99 1080 93 1086 108 0.0011 101 0.00103 2.490 1.040
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 385 794 376 803 577 0.00586 588 0.00598 -1.666 1.015
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 1113 66 1108 71 6974 0.0382 7168 0.0392 -6.238 1.015
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 1004 175 997 182 2424 0.0152 2426 0.0152 -0.151 1.007
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 42 1137 38 1141 42 0.00046 39 0.000427 1.771 1.004
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 57 1122 53 1126 61 0.000715 54 0.000633 3.666 0.955
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 1050 129 1045 134 3482 0.0272 3673 0.0287 -10.157 0.924
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 1108 71 1104 75 3655 0.0229 3635 0.0227 0.908 0.919
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 1098 81 1094 85 7244 0.0623 6992 0.0601 10.243 0.905
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 173 1006 168 1011 186 0.00174 190 0.00178 -1.027 0.898
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 1090 89 1086 93 3930 0.0215 4389 0.024 -18.595 0.895
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 11 1168 9 1170 11 0.000112 9 9.15e-05 2.355 0.888
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 434 745 428 751 559 0.00437 566 0.00442 -0.956 0.879
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 242 937 237 942 319 0.00349 282 0.00309 8.234 0.870
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 13 1166 11 1168 13 0.000142 11 0.00012 2.213 0.870
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 14 1165 12 1167 14 0.000186 12 0.000159 2.342 0.863
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 16 1163 14 1165 17 0.000226 14 0.000186 3.270 0.850
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 814 365 809 370 1400 0.0109 1516 0.0119 -9.508 0.845
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 738 441 733 446 1778 0.0167 2099 0.0197 -24.550 0.838
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 729 450 724 455 1471 0.0092 1587 0.00992 -8.306 0.838
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 534 645 529 650 828 0.00971 823 0.00965 0.649 0.834
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 1078 101 1075 104 6027 0.033 6581 0.036 -18.452 0.817
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 1043 136 1040 139 4607 0.0288 5711 0.0357 -42.124 0.801
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 141 1038 138 1041 154 0.00144 154 0.00144 -0.021 0.800
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 694 485 690 489 1304 0.0102 1388 0.0109 -7.199 0.798
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 148 1031 145 1034 178 0.00292 160 0.00263 6.507 0.798
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 55 1124 53 1126 57 0.000535 56 0.000525 0.438 0.775
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 820 359 817 362 2371 0.0167 2527 0.0178 -9.430 0.767
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 411 768 408 771 653 0.00612 697 0.00654 -5.818 0.765
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 722 457 719 460 1532 0.00958 1708 0.0107 -12.139 0.763
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 86 1093 84 1095 90 0.00113 95 0.00119 -2.074 0.759
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 1000 179 998 181 3553 0.0194 3835 0.021 -12.215 0.740
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 909 270 907 272 2648 0.0166 3057 0.0191 -21.162 0.733
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 5 1174 4 1175 5 6.64e-05 4 5.32e-05 1.999 0.693
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 5 1174 4 1175 5 5.86e-05 4 4.69e-05 1.870 0.693
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 123 1056 122 1057 128 0.001 135 0.00106 -1.928 0.693
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 35 1144 34 1145 35 0.000465 35 0.000465 -0.026 0.693
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 1005 174 1004 175 3972 0.031 4446 0.0348 -22.929 0.693
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 20 1159 19 1160 20 0.000234 19 0.000223 0.855 0.693
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 1071 108 1070 109 3283 0.0205 3731 0.0233 -21.031 0.693
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 1153 26 1152 27 5194 0.0325 5344 0.0334 -5.952 0.693
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 1179 0 1178 1 15896 0.0994 15988 0.1 -2.254 0.693
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 927 252 926 253 2110 0.0132 2052 0.0128 3.612 0.693
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 611 568 611 568 956 0.00747 1026 0.00802 -6.965 0.661
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 550 629 550 629 820 0.00961 857 0.01 -4.949 0.661
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 766 413 766 413 1315 0.0113 1324 0.0114 -0.856 0.659
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 919 260 919 260 2163 0.0169 1983 0.0155 12.846 0.654
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 95 1084 95 1084 97 0.000986 105 0.00107 -2.838 0.635
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 80 1099 80 1099 82 0.000769 83 0.000779 -0.403 0.630
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 570 609 571 608 1001 0.00939 1072 0.0101 -7.579 0.630
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 644 535 645 534 988 0.00849 1054 0.00906 -6.801 0.629
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 745 434 746 433 1435 0.0123 1454 0.0125 -1.695 0.627
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 840 339 841 338 2230 0.0139 2550 0.0159 -18.102 0.623
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 317 862 318 861 400 0.00375 399 0.00374 0.151 0.622
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 743 436 745 434 1276 0.011 1283 0.011 -0.683 0.596
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 797 382 799 380 1385 0.0108 1345 0.0105 3.437 0.593
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 98 1081 99 1080 107 0.00142 116 0.00154 -3.469 0.581
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 21 1158 21 1158 21 0.000263 21 0.000263 -0.031 0.577
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 569 610 572 607 807 0.00631 825 0.00645 -2.014 0.570
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 340 839 343 836 427 0.00267 419 0.00262 1.085 0.559
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 1124 55 1125 54 4206 0.0296 4555 0.032 -15.815 0.549
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 1048 131 1050 129 4787 0.0299 5379 0.0336 -23.271 0.548
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 48 1131 49 1130 49 0.000536 52 0.000569 -1.581 0.541
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 888 291 892 287 2348 0.0128 2537 0.0139 -10.030 0.520
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 679 500 684 495 1275 0.00797 1417 0.00886 -10.745 0.513
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 792 387 797 382 2339 0.0201 2805 0.0241 -29.580 0.504
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 7 1172 7 1172 7 0.000115 7 0.000115 -0.044 0.502
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 418 761 424 755 539 0.00548 525 0.00534 2.184 0.481
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 372 807 378 801 521 0.00611 530 0.00621 -1.544 0.476
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 42 1137 44 1135 45 0.000598 46 0.000611 -0.632 0.464
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 126 1053 130 1049 135 0.00179 146 0.00194 -3.778 0.463
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 879 300 885 294 1717 0.0134 1872 0.0146 -11.446 0.462
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 497 682 504 675 705 0.00661 711 0.00667 -0.808 0.461
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 488 691 495 684 752 0.0047 762 0.00477 -1.051 0.461
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 736 443 743 436 1241 0.0097 1327 0.0104 -7.534 0.457
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 36 1143 38 1141 40 0.000531 40 0.000532 -0.025 0.449
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 103 1076 107 1072 110 0.0012 116 0.00127 -2.107 0.445
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 206 973 212 967 228 0.00196 243 0.00209 -3.216 0.435
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 890 289 897 282 3220 0.0151 3997 0.0187 -30.425 0.431
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 920 259 927 252 1985 0.0155 1977 0.0155 0.538 0.423
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 1176 3 1176 3 9471 0.0666 9509 0.0669 -1.279 0.421
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 524 655 533 646 739 0.00462 768 0.0048 -2.991 0.415
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 1062 117 1067 112 4493 0.0386 4458 0.0383 1.720 0.413
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 10 1169 11 1168 10 0.000117 11 0.000129 -1.209 0.402
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 493 686 503 676 691 0.0054 792 0.00619 -11.409 0.390
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 284 895 293 886 340 0.00319 349 0.00327 -1.694 0.380
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 920 259 929 250 2941 0.0184 3310 0.0207 -18.369 0.369
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 50 1129 54 1125 51 0.000558 58 0.000635 -3.464 0.368
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 686 493 697 482 1329 0.0114 1473 0.0127 -12.555 0.368
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 752 427 764 415 1241 0.0097 1307 0.0102 -5.832 0.340
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 24 1155 27 1152 24 0.000263 27 0.000295 -2.190 0.337
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 587 592 600 579 961 0.00451 1027 0.00482 -5.080 0.331
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 12 1167 14 1165 12 0.000159 14 0.000186 -2.240 0.325
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 964 215 974 205 3459 0.0216 3962 0.0248 -22.928 0.324
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 1076 103 1083 96 3756 0.0323 3748 0.0322 0.392 0.324
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 926 253 937 242 3301 0.0206 3712 0.0232 -19.345 0.317
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 11 1168 13 1166 12 0.000159 13 0.000173 -1.180 0.314
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 112 1067 120 1059 121 0.00161 124 0.00165 -1.133 0.310
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 476 703 490 689 651 0.00763 713 0.00836 -9.058 0.308
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 1003 176 1013 166 4369 0.0273 5052 0.0316 -27.664 0.301
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 1042 137 1051 128 4436 0.0243 4655 0.0255 -8.645 0.297
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 72 1107 79 1100 73 0.000799 87 0.000952 -5.640 0.288
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 1178 1 1178 1 10144 0.0714 10064 0.0708 2.410 0.288
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 1 1178 1 1178 1 1.25e-05 1 1.25e-05 -0.126 0.288
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 53 1126 59 1120 55 0.000688 62 0.000775 -3.580 0.286
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 259 920 272 907 301 0.00259 328 0.00282 -4.973 0.281
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 244 935 257 922 271 0.00233 304 0.00261 -6.306 0.275
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 799 380 814 365 2059 0.0129 2258 0.0141 -11.962 0.273
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 130 1049 140 1039 138 0.00173 157 0.00196 -6.092 0.272
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 984 195 996 183 3240 0.0203 3600 0.0225 -17.204 0.265
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 792 387 808 371 1363 0.0117 1508 0.013 -12.497 0.257
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 493 686 510 669 683 0.00427 720 0.0045 -3.932 0.257
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 7 1172 9 1170 7 9.85e-05 10 0.000141 -4.065 0.257
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 285 894 300 879 347 0.00298 398 0.00342 -8.515 0.252
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 817 362 833 346 1801 0.0155 1935 0.0166 -10.223 0.252
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 937 242 951 228 3484 0.0218 4238 0.0265 -33.243 0.248
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 328 851 344 835 420 0.00394 453 0.00425 -5.405 0.247
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 19 1160 23 1156 19 0.000223 23 0.00027 -3.261 0.246
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 457 722 475 704 617 0.00627 657 0.00668 -5.671 0.238
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 62 1117 70 1109 68 0.000744 72 0.000788 -1.787 0.236
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 237 942 252 927 315 0.00295 341 0.0032 -4.907 0.233
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 44 1135 51 1128 44 0.000585 53 0.000704 -5.122 0.225
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 9 1170 12 1167 9 0.000113 12 0.00015 -3.503 0.211
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 461 718 481 698 615 0.00481 638 0.00499 -2.911 0.209
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 161 1018 175 1004 179 0.00154 198 0.0017 -4.503 0.209
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 2 1177 3 1176 2 2.66e-05 3 3.99e-05 -2.452 0.207
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 805 374 824 355 2454 0.0192 2877 0.0225 -25.262 0.206
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 812 367 831 348 1557 0.0134 1862 0.016 -23.666 0.205
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 560 619 581 598 859 0.00537 908 0.00568 -4.637 0.201
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 46 1133 54 1125 47 0.000514 57 0.000624 -4.981 0.197
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 138 1041 152 1027 151 0.00153 166 0.00169 -4.222 0.191
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 563 616 585 594 993 0.00776 1102 0.00861 -10.455 0.188
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 33 1146 40 1139 35 0.000438 42 0.000525 -4.346 0.187
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 517 662 539 640 788 0.00616 827 0.00646 -4.328 0.187
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 11 1168 15 1164 11 0.000138 15 0.000188 -4.167 0.177
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 59 1120 69 1110 60 0.000563 72 0.000675 -4.924 0.173
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 37 1142 45 1134 39 0.000488 45 0.000563 -3.603 0.169
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 858 321 879 300 1617 0.0101 1813 0.0113 -13.124 0.165
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 107 1072 121 1058 116 0.00109 130 0.00122 -4.277 0.160
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 1090 89 1102 77 3406 0.0266 3675 0.0287 -14.283 0.160
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 32 1147 40 1139 33 0.000361 40 0.000438 -4.168 0.152
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 762 417 786 393 1308 0.0102 1419 0.0111 -9.400 0.150
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 378 801 402 777 480 0.00375 530 0.00414 -6.905 0.147
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 585 594 611 568 921 0.00792 963 0.00828 -4.535 0.143
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 350 829 374 805 497 0.00466 537 0.00504 -6.018 0.142
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 44 1135 54 1125 48 0.0006 56 0.0007 -4.301 0.137
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 1177 2 1178 1 11166 0.0524 10811 0.0507 8.522 0.133
E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 1 1178 2 1177 1 1.25e-05 2 2.5e-05 -2.918 0.133
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 915 264 937 242 3202 0.02 3871 0.0242 -30.827 0.133
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 1019 160 1037 142 4732 0.0296 5527 0.0346 -30.829 0.129
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 293 886 317 862 376 0.00382 427 0.00434 -8.940 0.128
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 15 1164 21 1158 15 0.000188 22 0.000275 -6.001 0.127
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 123 1056 140 1039 140 0.00153 150 0.00164 -3.078 0.127
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 377 802 403 776 516 0.00444 582 0.005 -9.119 0.126
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 40 1139 50 1129 42 0.000525 55 0.000688 -7.037 0.126
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 372 807 398 781 573 0.00537 678 0.00636 -14.038 0.125
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 440 739 469 710 576 0.00585 623 0.00633 -6.836 0.108
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 205 974 228 951 242 0.00208 266 0.00229 -4.907 0.106
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 282 897 308 871 350 0.00274 370 0.00289 -3.314 0.105
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 126 1053 145 1034 139 0.00206 161 0.00239 -7.587 0.103
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 45 1134 57 1122 46 0.000575 57 0.000713 -5.853 0.099
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 61 1118 75 1104 62 0.000678 80 0.000876 -7.555 0.097
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 61 1118 75 1104 63 0.000837 79 0.00105 -7.447 0.097
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 406 773 436 743 659 0.00567 772 0.00664 -13.558 0.096
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 671 508 702 477 1168 0.01 1265 0.0109 -9.125 0.095
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 1000 179 1022 157 3770 0.0236 4161 0.026 -17.414 0.092
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 986 193 1009 170 2328 0.0182 2489 0.0195 -10.343 0.089
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 853 326 882 297 2168 0.0169 2577 0.0201 -25.775 0.084
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 788 391 819 360 2106 0.0165 2674 0.0209 -35.140 0.082
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 673 506 706 473 1309 0.0113 1605 0.0138 -24.706 0.081
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 110 1069 130 1049 129 0.00131 150 0.00152 -6.207 0.079
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 488 691 522 657 644 0.00554 698 0.006 -6.824 0.075
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 310 869 341 838 390 0.00305 413 0.00323 -3.606 0.073
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 530 649 565 614 1062 0.00913 1267 0.0109 -19.235 0.071
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 372 807 405 774 586 0.00504 700 0.00602 -14.358 0.071
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 678 501 713 466 1161 0.00907 1309 0.0102 -13.031 0.068
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 22 1157 32 1147 22 0.000206 35 0.000328 -7.641 0.067
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 996 183 1021 158 3592 0.0309 3522 0.0303 3.925 0.066
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 188 991 215 964 219 0.00308 245 0.00345 -7.081 0.065
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 503 676 539 640 696 0.00707 799 0.00812 -13.218 0.065
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 1 1178 3 1176 1 1.56e-05 3 4.69e-05 -5.230 0.064
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 170 1009 196 983 186 0.00204 219 0.0024 -8.374 0.064
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 17 1162 26 1153 18 0.000239 28 0.000372 -7.820 0.063
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 42 1137 56 1123 44 0.000619 58 0.000816 -7.824 0.063
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 218 961 247 932 260 0.00345 325 0.00432 -14.920 0.062
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 989 190 1015 164 2764 0.0173 3331 0.0208 -28.118 0.062
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 13 1166 21 1158 14 0.000186 22 0.000292 -7.063 0.061
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 434 745 470 709 620 0.00485 764 0.00597 -16.547 0.060
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 809 370 843 336 2060 0.0129 2551 0.016 -27.751 0.059
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 772 407 807 372 1340 0.00838 1475 0.00922 -10.016 0.059
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 995 184 1021 158 2430 0.0209 2528 0.0217 -6.576 0.059
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 273 906 305 874 377 0.00354 446 0.00418 -11.364 0.059
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 684 495 722 457 1193 0.00932 1364 0.0107 -14.749 0.052
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 619 560 658 521 947 0.00814 1014 0.00872 -7.037 0.050
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 4 1175 9 1170 4 5e-05 9 0.000113 -6.711 0.047
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 285 894 320 859 357 0.00279 418 0.00327 -9.472 0.046
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 183 996 213 966 243 0.00209 295 0.00254 -10.074 0.045
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 842 337 878 301 2748 0.0215 3489 0.0273 -40.263 0.044
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 749 430 788 391 1721 0.0121 2128 0.015 -26.701 0.043
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 574 605 615 564 940 0.00735 1084 0.00847 -13.916 0.043
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 223 956 256 923 249 0.00195 299 0.00234 -9.175 0.042
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 604 575 647 532 979 0.00689 1153 0.00811 -15.462 0.035
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 934 245 968 211 2132 0.015 2248 0.0158 -7.433 0.035
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 750 429 792 387 1270 0.00993 1456 0.0114 -15.533 0.032
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 962 217 995 184 2886 0.018 3009 0.0188 -6.440 0.032
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 499 680 543 636 790 0.00741 890 0.00835 -11.687 0.031
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 714 465 757 422 1758 0.0151 2092 0.018 -24.475 0.031
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 934 245 969 210 2554 0.016 2722 0.017 -9.222 0.031
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 721 458 765 414 1597 0.0125 2015 0.0158 -29.714 0.028
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 551 628 597 582 795 0.00621 911 0.00712 -12.222 0.027
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 149 1030 181 998 180 0.00225 212 0.00265 -8.823 0.025
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 854 325 895 284 2921 0.0205 3598 0.0253 -34.336 0.024
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 561 618 608 571 846 0.00661 939 0.00734 -9.659 0.024
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 778 401 822 357 1304 0.0112 1531 0.0132 -19.400 0.024
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 97 1082 125 1054 100 0.000938 134 0.00126 -10.201 0.021
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 31 1148 48 1131 31 0.000412 50 0.000664 -11.105 0.020
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 3 1176 9 1170 3 4.22e-05 9 0.000127 -8.527 0.019
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 258 921 300 879 363 0.00312 440 0.00378 -12.219 0.019
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 1035 144 1066 113 3039 0.0261 2914 0.0251 7.734 0.017
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 814 365 860 319 2254 0.0159 2646 0.0186 -23.113 0.017
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 1 1178 5 1174 1 1.56e-05 5 7.82e-05 -8.052 0.016
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 230 949 272 907 311 0.00316 393 0.00399 -14.965 0.015
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 416 763 466 713 526 0.00411 648 0.00507 -15.217 0.015
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 940 239 980 199 2258 0.0159 2758 0.0194 -28.879 0.015
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 566 613 618 561 881 0.00689 1042 0.00815 -15.863 0.015
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 1008 171 1043 136 3802 0.0238 4787 0.0299 -40.926 0.014
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 127 1052 162 1017 149 0.00163 192 0.0021 -11.643 0.012
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 9 1170 20 1159 9 0.00012 20 0.000266 -10.173 0.012
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 687 492 740 439 1556 0.00851 1913 0.0105 -21.737 0.012
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 944 235 986 193 3633 0.0227 4346 0.0272 -31.056 0.011
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 1100 79 1125 54 3625 0.0227 3827 0.0239 -9.389 0.010
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 843 336 892 287 2655 0.0166 3408 0.0213 -36.914 0.010
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 221 958 266 913 270 0.00274 322 0.00327 -10.486 0.010
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 317 862 368 811 381 0.00387 454 0.00461 -12.404 0.009
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 871 308 919 260 2621 0.0287 2807 0.0307 -13.388 0.009
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 890 289 937 242 1800 0.0127 1938 0.0136 -9.501 0.009
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 297 882 348 831 340 0.00292 438 0.00377 -15.581 0.008
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 633 546 690 489 1120 0.00963 1590 0.0137 -39.392 0.008
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 1000 179 1040 139 3207 0.0201 3771 0.0236 -26.328 0.007
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 107 1072 144 1035 111 0.00104 159 0.00149 -13.216 0.006
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 280 899 334 845 336 0.00289 433 0.00372 -15.510 0.005
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 798 381 855 324 1856 0.0145 2212 0.0173 -24.180 0.005
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 939 240 987 192 2048 0.016 2306 0.018 -17.181 0.005
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 578 601 641 538 1301 0.0112 1626 0.014 -26.951 0.004
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 248 931 302 877 305 0.00238 385 0.00301 -12.933 0.004
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 163 1016 210 969 196 0.0023 266 0.00312 -16.669 0.003
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 752 427 815 364 2019 0.0126 2605 0.0163 -32.774 0.003
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 534 645 602 577 768 0.006 925 0.00723 -16.408 0.002
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 736 443 801 378 1716 0.0134 2261 0.0177 -36.603 0.002
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 848 331 908 271 1787 0.0126 1965 0.0138 -12.163 0.002
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 270 909 330 849 322 0.00327 433 0.0044 -19.297 0.002
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 478 701 548 631 768 0.009 1010 0.0118 -29.696 0.002
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 303 876 368 811 379 0.00296 481 0.00376 -14.756 0.001
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 232 947 292 887 315 0.00271 396 0.00341 -13.544 0.001
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 227 952 287 892 256 0.003 331 0.00388 -16.018 0.001
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 869 310 931 248 2496 0.0195 3067 0.024 -33.041 0.001
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 274 905 338 841 335 0.00262 448 0.0035 -16.933 0.001
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 202 977 260 919 221 0.00328 291 0.00432 -17.947 0.001
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 675 504 749 430 1462 0.00914 1979 0.0124 -33.105 0.001
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 350 829 422 757 481 0.00414 611 0.00525 -17.511 0.001
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 298 881 368 811 386 0.00302 506 0.00396 -16.924 0.001
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 779 400 851 328 1563 0.0122 2238 0.0175 -45.552 0.001
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 307 872 378 801 433 0.00474 612 0.0067 -27.188 0.001
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 607 572 685 494 1307 0.0123 1842 0.0173 -43.592 0.001
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 734 445 809 370 1691 0.0132 2432 0.019 -48.007 0.000
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 2 1177 13 1166 2 2.5e-05 13 0.000163 -12.241 0.000
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 23 1156 50 1129 24 0.000319 53 0.000704 -16.452 0.000
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 541 638 622 557 974 0.0114 1472 0.0173 -50.742 0.000
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 311 868 387 792 400 0.00313 536 0.00419 -18.636 0.000
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 247 932 318 861 278 0.00217 386 0.00302 -17.429 0.000
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 178 1001 242 937 198 0.00186 306 0.00287 -21.437 0.000
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 60 1119 102 1077 60 0.000563 108 0.00101 -16.028 0.000
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 677 502 760 419 1079 0.00843 1316 0.0103 -20.794 0.000
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 164 1015 227 952 196 0.00153 280 0.00219 -15.911 0.000
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 489 690 574 605 768 0.006 975 0.00762 -21.069 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 306 873 384 795 364 0.00341 488 0.00458 -19.511 0.000
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 152 1027 216 963 187 0.0019 266 0.0027 -17.508 0.000
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 612 567 702 477 907 0.00567 1126 0.00704 -18.549 0.000
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 600 579 691 488 1114 0.00871 1591 0.0124 -38.082 0.000
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 111 1068 170 1009 127 0.000993 195 0.00152 -15.430 0.000
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 298 881 383 796 413 0.00323 591 0.00462 -23.229 0.000
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 345 834 434 745 413 0.00613 627 0.00931 -37.452 0.000
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 646 533 740 439 1303 0.0102 1852 0.0145 -40.666 0.000
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 285 894 373 806 404 0.00347 548 0.00471 -20.472 0.000
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 742 437 835 344 1636 0.0128 1917 0.015 -20.482 0.000
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 502 677 606 573 703 0.00549 896 0.007 -20.485 0.000
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 574 605 679 500 819 0.00832 1013 0.0103 -22.119 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 430 749 540 639 530 0.00497 716 0.00672 -24.184 0.000
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 87 1092 159 1020 97 0.00106 199 0.00218 -27.102 0.000
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 711 468 826 353 1152 0.009 1459 0.0114 -25.591 0.000
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 25 1154 73 1106 26 0.000325 75 0.000938 -22.662 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 23 1156 70 1109 23 0.00027 74 0.000868 -22.991 0.000
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 167 1012 266 913 180 0.00141 311 0.00243 -23.538 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 289 890 409 770 392 0.00368 639 0.00599 -33.972 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 183 996 289 890 207 0.00194 386 0.00362 -31.637 0.000
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 277 902 399 780 314 0.00245 502 0.00392 -26.606 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 256 923 377 802 325 0.00305 573 0.00538 -36.007 0.000
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 82 1097 168 1011 97 0.00106 209 0.00229 -29.039 0.000
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 247 932 373 806 279 0.00218 457 0.00357 -26.397 0.000
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 71 1108 161 1018 83 0.000908 205 0.00224 -31.936 0.000

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HOMER results

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