Human Analysis


Summary

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Job ID: FF:10016-101C7
Number of target experiments: 1
Number of target CAGE peaks: 1219
Number of target CAGE peak regions: 832
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 832
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:10016-101C7 heart, adult, pool1


Results

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Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 636 196 520 312 1737 0.0192 1350 0.0149 33.409 21.615
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 735 97 667 165 3492 0.0463 2882 0.0382 39.906 12.733
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 622 210 539 293 1593 0.0369 1146 0.0266 61.123 12.054
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 708 124 637 195 3021 0.0367 2520 0.0307 33.414 12.003
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 723 109 656 176 3226 0.0428 2628 0.0349 40.911 11.716
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 224 608 153 679 288 0.00318 174 0.00192 27.283 10.823
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 644 188 570 262 3147 0.0382 2691 0.0327 29.434 10.510
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 357 475 278 554 504 0.00835 393 0.00652 21.654 10.107
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 768 64 719 113 5785 0.0767 4962 0.0658 41.575 9.682
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 586 246 511 321 1077 0.0119 881 0.00974 20.865 9.661
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 786 46 747 85 2855 0.041 2405 0.0346 33.455 8.292
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 482 350 413 419 806 0.0107 718 0.00953 11.318 7.797
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 772 60 731 101 2462 0.0299 2080 0.0253 27.953 7.747
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 45 787 19 813 47 0.000727 20 0.00031 22.533 7.367
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 497 335 431 401 918 0.0132 737 0.0106 24.042 7.317
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 500 332 435 397 1008 0.0145 817 0.0117 24.105 7.158
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 187 645 138 694 231 0.00408 172 0.00304 17.946 6.516
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 721 111 676 156 3851 0.0638 3237 0.0537 42.694 6.425
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 319 513 263 569 390 0.00431 341 0.00377 8.330 6.059
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 270 562 217 615 368 0.0061 274 0.00454 21.954 5.981
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 663 169 614 218 1450 0.016 1290 0.0143 14.052 5.932
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 693 139 649 183 1650 0.0146 1424 0.0126 16.916 5.578
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 328 504 276 556 438 0.00581 362 0.0048 13.784 5.371
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 241 591 195 637 344 0.00646 309 0.00581 8.143 5.110
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 685 147 643 189 3914 0.0476 3453 0.042 26.350 5.098
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 750 82 716 116 4030 0.049 3390 0.0412 36.995 5.090
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 12 820 2 830 12 0.000212 2 3.54e-05 28.175 5.069
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 552 280 502 330 946 0.0157 859 0.0142 11.444 5.064
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 798 34 775 57 3402 0.0413 2854 0.0347 34.410 4.753
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 216 616 174 658 287 0.00475 249 0.00413 9.266 4.734
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 641 191 598 234 1209 0.0147 1288 0.0157 -7.489 4.701
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 390 442 342 490 636 0.0105 537 0.00891 16.507 4.593
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 657 175 616 216 2067 0.0274 1873 0.0249 15.548 4.573
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 585 247 540 292 1139 0.0126 997 0.011 14.178 4.550
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 385 447 338 494 622 0.00962 563 0.00872 9.237 4.471
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 447 385 400 432 836 0.012 689 0.0099 20.173 4.420
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 342 490 297 535 491 0.00813 398 0.0066 18.014 4.322
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 440 392 394 438 902 0.012 835 0.0111 7.958 4.293
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 559 273 515 317 1100 0.0121 938 0.0104 16.694 4.286
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 693 139 657 175 1992 0.0242 1762 0.0214 18.204 4.261
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 46 786 27 805 49 0.00092 27 0.000508 17.405 4.182
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 661 171 623 209 1660 0.0202 1447 0.0176 18.584 4.179
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 761 71 734 98 2141 0.0236 2140 0.0237 -0.095 4.057
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 781 51 759 73 3330 0.0368 2681 0.0296 40.032 3.697
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 27 805 14 818 27 0.000477 16 0.000283 10.947 3.567
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 146 686 117 715 171 0.00283 143 0.00237 9.013 3.511
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 468 364 429 403 779 0.0103 696 0.00924 10.838 3.480
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 42 790 26 806 42 0.000789 26 0.000489 12.887 3.465
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 348 484 310 522 485 0.00536 402 0.00445 13.036 3.449
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 167 665 137 695 193 0.00298 152 0.00235 12.390 3.416
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 43 789 27 805 45 0.000845 27 0.000508 14.232 3.407
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 239 593 205 627 333 0.00552 283 0.00469 11.453 3.391
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 405 427 367 465 632 0.0105 588 0.00975 6.950 3.368
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 831 1 825 7 6402 0.0636 6587 0.0656 -7.347 3.357
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 211 621 179 653 249 0.00358 210 0.00302 9.646 3.314
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 437 395 400 432 665 0.00808 585 0.00712 10.909 3.250
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 272 560 239 593 371 0.00574 326 0.00505 9.263 3.113
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 8 824 2 830 8 0.000124 2 3.1e-05 15.766 2.916
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 205 627 177 655 262 0.00203 207 0.0016 10.062 2.852
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 816 16 805 27 4692 0.0363 4091 0.0317 25.060 2.802
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 388 444 356 476 704 0.00855 663 0.00806 5.200 2.762
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 721 111 698 134 2148 0.0166 2054 0.0159 5.393 2.750
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 815 17 804 28 3693 0.0326 3664 0.0324 1.184 2.734
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 810 22 798 34 3583 0.0396 3495 0.0386 4.588 2.702
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 827 5 820 12 4514 0.0449 4807 0.0478 -13.220 2.649
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 102 730 83 749 116 0.00256 93 0.00206 10.613 2.524
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 130 702 109 723 154 0.00255 131 0.00217 7.727 2.513
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 550 282 522 310 1242 0.011 1255 0.0111 -1.158 2.484
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 319 513 291 541 423 0.00467 364 0.00402 9.719 2.468
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 635 197 610 222 1359 0.012 1333 0.0118 1.907 2.435
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 752 80 734 98 2709 0.0299 2578 0.0285 8.093 2.422
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 101 731 83 749 112 0.00161 89 0.00128 8.739 2.387
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 439 393 411 421 734 0.00892 700 0.00851 4.176 2.378
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 30 802 20 812 30 0.000563 21 0.000395 8.048 2.324
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 55 777 42 790 57 0.000944 42 0.000697 8.915 2.258
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 40 792 29 803 41 0.000543 31 0.000411 6.173 2.214
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 441 391 415 417 739 0.0114 676 0.0105 8.998 2.207
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 754 78 738 94 2162 0.0239 2262 0.025 -6.899 2.176
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 479 353 454 378 696 0.00769 720 0.00796 -2.937 2.138
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 417 415 392 440 625 0.00759 592 0.0072 4.418 2.124
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 36 796 26 806 37 0.000695 28 0.000526 6.964 2.104
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 832 0 829 3 7586 0.0503 7899 0.0524 -9.103 2.081
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 207 625 187 645 250 0.00387 240 0.00372 2.347 1.991
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 743 89 728 104 2636 0.0291 2465 0.0273 10.861 1.953
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 211 621 192 640 265 0.00293 224 0.00248 8.607 1.887
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 459 373 438 394 857 0.00947 857 0.00948 -0.107 1.816
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 7 825 3 829 7 0.000139 3 5.97e-05 9.717 1.765
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 33 799 25 807 37 0.000654 27 0.000478 7.649 1.744
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 742 90 729 103 2865 0.0316 2717 0.03 8.927 1.720
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 271 561 253 579 366 0.00606 345 0.00572 4.303 1.688
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 19 813 13 819 20 0.000376 14 0.000263 6.560 1.681
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 95 737 83 749 105 0.00139 91 0.00121 5.033 1.653
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 248 584 231 601 307 0.00407 279 0.0037 5.743 1.644
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 52 780 43 789 53 0.000878 45 0.000746 4.570 1.614
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 367 465 349 483 513 0.0068 483 0.00641 4.652 1.610
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 223 609 207 625 265 0.0041 238 0.00368 6.485 1.607
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 114 718 102 730 135 0.00239 113 0.002 8.224 1.555
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 130 702 118 714 148 0.0018 131 0.00159 4.873 1.494
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 647 185 633 199 1317 0.0145 1372 0.0152 -4.862 1.493
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 512 320 496 336 1052 0.0105 1016 0.0101 3.294 1.488
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 28 804 22 810 30 0.00053 23 0.000407 5.789 1.442
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 745 87 735 97 4058 0.0448 4286 0.0474 -11.511 1.423
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 485 347 470 362 1036 0.00915 1071 0.00947 -3.144 1.411
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 61 771 53 779 66 0.00117 56 0.000991 5.296 1.392
*TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 2 830 0 832 2 4.42e-05 0 0 NA 1.387
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 139 693 128 704 154 0.00238 156 0.00241 -0.661 1.378
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 113 719 103 729 133 0.00191 132 0.0019 0.257 1.363
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 434 398 420 412 680 0.00751 702 0.00776 -2.732 1.340
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 719 113 709 123 2596 0.0229 2801 0.0248 -11.256 1.333
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 23 809 18 814 23 0.000356 19 0.000294 3.384 1.333
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 73 759 65 767 78 0.00129 69 0.00114 4.146 1.321
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 320 512 307 525 413 0.00593 423 0.00608 -1.845 1.302
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 345 487 332 500 581 0.00513 564 0.00499 1.948 1.292
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 370 462 357 475 541 0.00896 479 0.00794 10.911 1.285
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 758 74 750 82 5487 0.0848 4764 0.0737 40.408 1.280
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 646 186 635 197 1361 0.015 1305 0.0144 4.806 1.272
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 300 532 288 544 399 0.00573 372 0.00535 4.975 1.251
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 66 766 59 773 69 0.000915 63 0.000836 2.570 1.243
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 17 815 13 819 19 0.000378 16 0.000318 3.133 1.236
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 377 455 365 467 662 0.00731 652 0.00721 1.148 1.225
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 466 366 454 378 816 0.00991 790 0.00961 2.974 1.225
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 182 650 172 660 210 0.00255 197 0.0024 3.012 1.221
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 3 829 1 831 3 5.96e-05 1 1.99e-05 8.358 1.164
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 831 1 829 3 7428 0.0738 7122 0.0709 10.991 1.164
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 797 35 792 40 3214 0.0355 3187 0.0352 1.338 1.145
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 665 167 657 175 1653 0.0183 1615 0.0179 2.872 1.092
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 52 780 47 785 54 0.000954 52 0.00092 1.061 1.081
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 127 705 120 712 143 0.00221 134 0.00207 2.852 1.080
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 85 747 79 753 94 0.00125 86 0.00114 2.938 1.077
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 340 492 331 501 501 0.00775 494 0.00765 1.085 1.065
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 664 168 657 175 1505 0.0183 1497 0.0182 0.547 1.027
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 302 530 294 538 414 0.0064 402 0.00622 2.157 1.021
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 72 760 67 765 89 0.00177 89 0.00177 -0.056 1.017
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 78 754 73 759 84 0.0013 77 0.00119 2.934 1.004
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 704 128 698 134 1812 0.022 1709 0.0208 8.192 0.999
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 756 76 751 81 2346 0.0207 2285 0.0202 3.492 0.998
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 81 751 76 756 89 0.00118 80 0.00106 3.436 0.998
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 20 812 17 815 21 0.000418 18 0.000358 2.952 0.994
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 6 826 4 828 6 9.28e-05 4 6.19e-05 3.665 0.977
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 504 328 497 335 811 0.00985 908 0.011 -10.844 0.963
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 25 807 22 810 25 0.000387 22 0.000341 2.345 0.958
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 538 294 532 300 964 0.0117 918 0.0112 4.946 0.919
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 88 744 84 748 100 0.00133 102 0.00135 -0.738 0.905
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 205 627 200 632 243 0.00242 245 0.00244 -0.445 0.892
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 721 111 717 115 3126 0.0276 3621 0.032 -23.827 0.879
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 59 773 56 776 64 0.00106 64 0.00106 -0.050 0.859
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 17 815 15 817 18 0.000338 16 0.000301 2.012 0.846
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 73 759 70 762 81 0.00116 75 0.00108 2.448 0.843
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 79 753 76 756 87 0.00135 93 0.00144 -2.382 0.837
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 156 676 153 679 186 0.00288 173 0.00268 3.637 0.799
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 36 796 34 798 37 0.000654 36 0.000637 0.620 0.795
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 41 791 39 793 45 0.000696 40 0.000619 2.910 0.789
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 52 780 50 782 54 0.000835 55 0.000851 -0.553 0.778
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 93 739 91 741 105 0.00186 98 0.00173 2.774 0.757
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 682 150 680 152 2626 0.029 2941 0.0325 -18.857 0.745
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 42 790 41 791 42 0.000696 47 0.00078 -2.872 0.693
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 120 712 119 713 132 0.00262 128 0.00255 1.438 0.693
*PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 1 831 0 832 2 4.42e-05 0 0 NA 0.693
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 757 75 756 76 2707 0.0299 2444 0.027 16.870 0.693
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 11 821 10 822 11 0.000194 10 0.000177 1.211 0.693
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 51 781 50 782 55 0.00085 50 0.000774 2.598 0.693
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 8 824 7 825 8 0.000124 7 0.000108 1.352 0.693
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 12 820 11 821 12 0.000199 11 0.000182 1.114 0.693
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 325 507 325 507 494 0.00437 491 0.00434 0.307 0.654
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 522 310 522 310 1559 0.0189 1798 0.0219 -19.050 0.654
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 255 577 255 577 335 0.00555 357 0.00592 -4.607 0.652
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 618 214 618 214 2272 0.0151 2494 0.0165 -11.112 0.649
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 183 649 183 649 217 0.00407 219 0.00412 -0.633 0.647
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 706 126 706 126 1683 0.0167 1838 0.0183 -11.086 0.640
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 715 117 715 117 2283 0.0202 2578 0.0228 -16.777 0.638
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 748 84 748 84 4020 0.0311 4442 0.0344 -17.237 0.630
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 429 403 430 402 865 0.00764 894 0.00791 -2.851 0.618
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 202 630 203 629 240 0.00265 240 0.00265 -0.064 0.606
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 38 794 38 794 40 0.000619 40 0.000619 -0.047 0.604
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 158 674 159 673 189 0.00313 192 0.00318 -0.907 0.598
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 706 126 707 125 2741 0.0333 2519 0.0306 14.705 0.590
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 27 805 27 805 27 0.000358 28 0.000372 -0.702 0.589
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 400 432 402 430 764 0.0127 905 0.015 -18.413 0.582
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 750 82 751 81 3343 0.0406 3220 0.0392 7.118 0.570
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 16 816 16 816 16 0.000212 17 0.000226 -0.890 0.561
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 513 319 516 316 896 0.0139 917 0.0142 -2.741 0.545
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 47 785 48 784 49 0.000758 52 0.000805 -1.604 0.539
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 717 115 719 113 2687 0.0237 3146 0.0278 -23.641 0.537
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 211 621 214 618 294 0.00325 320 0.00354 -4.672 0.529
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 791 41 792 40 7402 0.0899 6164 0.075 54.050 0.528
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 744 88 746 86 2308 0.0204 2510 0.0222 -11.686 0.519
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 558 274 562 270 1218 0.0135 1391 0.0154 -14.908 0.506
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 768 64 770 62 5299 0.0585 4540 0.0502 36.291 0.495
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 6 826 6 826 6 0.000113 6 0.000113 -0.060 0.489
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 22 810 23 809 24 0.000451 23 0.000432 0.813 0.480
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 407 425 413 419 903 0.00898 990 0.00985 -8.440 0.455
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 471 361 477 355 821 0.00997 916 0.0111 -10.578 0.453
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 4 828 4 828 4 7.51e-05 4 7.52e-05 -0.070 0.451
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 649 183 654 178 1718 0.0152 1801 0.0159 -5.709 0.447
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 33 799 35 797 35 0.000619 37 0.000655 -1.362 0.439
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 252 580 258 574 353 0.00429 354 0.00431 -0.253 0.438
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 30 802 32 800 30 0.000563 32 0.000602 -1.504 0.429
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 690 142 695 137 1579 0.0174 1764 0.0195 -14.209 0.426
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 87 745 91 741 95 0.00105 113 0.00125 -5.407 0.424
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 489 343 496 336 1105 0.0183 1184 0.0196 -9.126 0.423
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 24 808 26 806 24 0.000451 27 0.000508 -2.426 0.406
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 585 247 592 240 1261 0.0139 1294 0.0143 -3.050 0.405
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 409 423 417 415 583 0.00644 671 0.00742 -10.873 0.400
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 683 149 689 143 1563 0.0173 1692 0.0187 -10.153 0.394
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 9 823 10 822 9 0.000179 10 0.000199 -1.393 0.390
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 38 794 41 791 40 0.000663 42 0.000697 -1.242 0.389
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 2 830 2 830 2 3.53e-05 2 3.54e-05 -0.094 0.374
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 2 830 2 830 2 3.76e-05 2 3.76e-05 -0.092 0.374
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 468 364 477 355 721 0.00876 820 0.00997 -11.627 0.372
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 32 800 35 797 33 0.000437 36 0.000478 -1.778 0.370
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 717 115 723 109 3148 0.0278 3439 0.0304 -14.432 0.368
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 798 34 801 31 3029 0.0301 3203 0.0319 -9.560 0.366
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 30 802 33 799 30 0.000596 34 0.000677 -2.957 0.362
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 143 689 150 682 166 0.0033 173 0.00344 -2.330 0.361
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 386 446 396 436 609 0.0074 652 0.00793 -5.703 0.349
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 341 491 351 481 442 0.00537 470 0.00572 -4.379 0.346
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 6 826 7 825 6 0.000106 7 0.000124 -1.570 0.342
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 664 168 672 160 2139 0.0189 2348 0.0208 -12.476 0.342
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 24 808 27 805 24 0.000451 29 0.000545 -3.874 0.335
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 81 751 87 745 89 0.00167 97 0.00182 -3.407 0.335
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 38 794 42 790 39 0.000732 45 0.000846 -3.736 0.333
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 552 280 562 270 974 0.0108 933 0.0103 4.154 0.333
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 184 648 193 639 241 0.00319 281 0.00373 -8.349 0.327
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 36 796 40 792 37 0.000572 43 0.000666 -3.470 0.327
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 179 653 188 644 227 0.00276 262 0.00319 -7.247 0.325
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 22 810 25 807 24 0.000371 27 0.000418 -2.206 0.325
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 488 344 499 333 979 0.0119 1018 0.0124 -4.198 0.321
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 600 232 610 222 1138 0.0126 1293 0.0143 -13.851 0.318
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 308 524 319 513 537 0.00534 597 0.00594 -7.472 0.317
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 782 50 787 45 4673 0.0568 4257 0.0518 21.460 0.305
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 461 371 473 359 1005 0.00888 1034 0.00915 -2.666 0.302
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 785 47 790 42 5560 0.043 6065 0.0469 -17.796 0.297
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 171 661 181 651 215 0.00237 232 0.00257 -3.595 0.294
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 653 179 663 169 1588 0.0158 1876 0.0187 -20.272 0.293
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 17 815 20 812 17 0.000282 20 0.000332 -2.645 0.292
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 749 83 756 76 2610 0.0202 2979 0.0231 -18.250 0.291
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 537 295 549 283 925 0.0102 1044 0.0115 -11.825 0.290
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 726 106 734 98 2025 0.0246 2020 0.0246 0.206 0.288
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 752 80 759 73 2615 0.0318 2590 0.0315 1.465 0.286
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 564 268 576 256 989 0.0109 1009 0.0112 -2.116 0.283
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 440 392 453 379 671 0.00815 838 0.0102 -19.331 0.282
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 374 458 387 445 562 0.00931 580 0.00962 -3.015 0.282
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 705 127 714 118 2030 0.0224 2014 0.0223 0.980 0.280
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 24 808 28 804 25 0.000442 29 0.000513 -3.017 0.275
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 684 148 694 138 1686 0.0149 1676 0.0148 0.564 0.271
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 406 426 420 412 677 0.00673 744 0.0074 -7.488 0.263
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 44 788 50 782 46 0.00061 53 0.000703 -3.377 0.260
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 7 825 9 823 7 0.000131 9 0.000169 -2.801 0.256
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 7 825 9 823 7 0.000116 9 0.000149 -2.636 0.256
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 632 200 644 188 2330 0.0206 2694 0.0238 -20.231 0.256
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 42 790 48 784 45 0.000596 51 0.000677 -2.957 0.254
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 56 776 63 769 61 0.00115 74 0.00139 -6.285 0.253
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 72 760 80 752 80 0.00115 92 0.00132 -4.564 0.251
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 605 227 618 214 1786 0.0158 2004 0.0177 -14.033 0.246
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 659 173 671 161 2019 0.0178 1968 0.0174 3.137 0.240
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 50 782 57 775 50 0.000773 73 0.00113 -10.123 0.238
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 6 826 8 824 6 9.94e-05 8 0.000133 -2.795 0.237
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 64 768 72 760 67 0.000888 89 0.00118 -8.130 0.236
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 138 694 150 682 150 0.00182 180 0.00219 -7.480 0.223
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 73 759 82 750 78 0.00121 91 0.00141 -5.153 0.223
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 109 723 120 712 129 0.00214 151 0.0025 -7.001 0.219
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 162 670 175 657 184 0.00264 226 0.00325 -10.152 0.219
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 713 119 724 108 1805 0.0219 1884 0.0229 -6.266 0.218
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 159 673 172 660 212 0.00304 247 0.00355 -8.110 0.217
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 661 171 674 158 1756 0.0194 1731 0.0191 1.769 0.216
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 771 61 779 53 5666 0.0688 5181 0.063 22.804 0.212
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 536 296 552 280 1383 0.0122 1489 0.0132 -7.941 0.211
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 772 60 780 52 2530 0.0224 2641 0.0234 -6.342 0.210
SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 2 830 3 829 2 3.53e-05 3 5.31e-05 -2.388 0.207
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 463 369 480 352 1170 0.0155 1367 0.0181 -18.762 0.207
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 168 664 182 650 220 0.00292 235 0.00312 -3.460 0.203
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 202 630 217 615 247 0.00273 273 0.00302 -5.047 0.202
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 113 719 125 707 136 0.0015 160 0.00177 -6.058 0.200
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 684 148 697 135 2971 0.0263 3344 0.0296 -18.694 0.199
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 13 819 17 815 13 0.000201 18 0.000279 -4.457 0.197
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 8 824 11 821 8 0.000141 11 0.000195 -3.669 0.196
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 391 441 409 423 626 0.00415 764 0.00507 -12.335 0.193
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 430 402 448 384 643 0.00781 758 0.00922 -14.016 0.193
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 826 6 828 4 9530 0.0632 8489 0.0563 28.219 0.188
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 4 828 6 826 4 9.28e-05 6 0.000139 -3.797 0.188
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 678 154 692 140 2925 0.0226 3206 0.0248 -13.458 0.183
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 234 598 251 581 378 0.00501 430 0.00571 -8.792 0.181
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 7 825 10 822 7 0.000131 10 0.000188 -3.962 0.180
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 90 742 102 730 93 0.00195 113 0.00237 -8.268 0.173
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 748 84 759 73 2508 0.0277 2418 0.0267 5.689 0.171
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 57 775 67 765 65 0.000933 70 0.00101 -2.204 0.165
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 10 822 14 818 10 0.000188 14 0.000263 -4.455 0.165
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 56 776 66 766 57 0.000881 73 0.00113 -7.057 0.163
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 333 499 353 479 682 0.00829 813 0.00989 -15.414 0.160
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 174 658 191 641 229 0.00278 270 0.00328 -8.353 0.154
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 515 317 535 297 823 0.00909 962 0.0106 -14.353 0.154
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 372 460 393 439 655 0.00868 743 0.00986 -11.342 0.150
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 445 387 466 366 912 0.0111 1008 0.0123 -10.205 0.150
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 772 60 782 50 4606 0.0356 4847 0.0375 -9.537 0.150
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 13 819 18 814 13 0.000215 18 0.000299 -4.611 0.149
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 507 325 528 304 829 0.00916 997 0.011 -17.024 0.143
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 79 753 92 740 85 0.00113 115 0.00153 -9.747 0.138
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 446 386 468 364 901 0.0109 1030 0.0125 -13.529 0.138
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 581 251 601 231 1630 0.0126 1667 0.0129 -2.535 0.137
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 466 366 488 344 896 0.0099 917 0.0101 -2.313 0.136
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 1 831 2 830 1 2.32e-05 2 4.64e-05 -3.323 0.133
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 252 580 273 559 417 0.00553 469 0.00622 -8.428 0.131
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 21 811 28 804 22 0.000437 30 0.000597 -6.242 0.131
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 241 591 262 570 341 0.0049 421 0.00605 -14.181 0.128
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 760 72 772 60 2231 0.0197 2328 0.0206 -5.896 0.127
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 531 301 553 279 1379 0.0122 1629 0.0144 -17.767 0.126
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 491 341 514 318 788 0.00696 893 0.0079 -10.071 0.122
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 623 209 643 189 2263 0.02 2430 0.0215 -9.839 0.121
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 744 88 758 74 3422 0.0302 3953 0.035 -24.503 0.114
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 17 815 24 808 17 0.000263 25 0.000387 -6.032 0.108
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 511 321 535 297 838 0.0102 972 0.0118 -14.450 0.108
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 162 670 182 650 185 0.00307 210 0.00348 -6.760 0.107
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 627 205 648 184 1920 0.0297 2102 0.0325 -15.285 0.107
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 528 304 552 280 1439 0.0127 1648 0.0146 -14.791 0.105
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 88 744 104 728 101 0.0019 110 0.00207 -3.599 0.101
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 100 732 117 715 107 0.00118 128 0.00142 -5.924 0.100
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 552 280 576 256 883 0.00878 990 0.00985 -10.356 0.100
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 129 703 148 684 143 0.00158 177 0.00196 -8.143 0.099
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 552 280 577 255 1144 0.0139 1337 0.0163 -17.778 0.090
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 23 809 32 800 23 0.000356 32 0.000495 -5.998 0.089
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 562 270 587 245 1419 0.0157 1596 0.0176 -14.271 0.088
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 211 621 235 597 254 0.00224 302 0.00267 -7.882 0.087
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 346 486 373 459 537 0.00712 620 0.00823 -11.689 0.087
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 527 305 553 279 842 0.0093 1023 0.0113 -18.103 0.086
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 75 757 91 741 96 0.00148 110 0.0017 -5.052 0.086
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 335 497 362 470 436 0.00385 546 0.00483 -13.420 0.086
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 175 657 198 634 211 0.0028 263 0.00349 -11.191 0.082
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 764 68 778 54 2281 0.0252 2536 0.028 -16.412 0.082
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 195 637 219 613 268 0.00296 293 0.00324 -4.692 0.081
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 574 258 600 232 1234 0.0123 1382 0.0138 -12.147 0.076
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 580 252 606 226 2014 0.02 2329 0.0232 -19.965 0.074
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 406 426 435 397 657 0.00726 753 0.00833 -11.204 0.073
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 238 594 265 567 338 0.00448 383 0.00508 -8.063 0.070
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 680 152 702 130 2030 0.0179 2305 0.0204 -16.513 0.069
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 226 606 253 579 296 0.00392 379 0.00503 -14.879 0.067
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 252 580 280 552 349 0.00463 418 0.00555 -11.802 0.066
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 2 830 5 827 2 3.31e-05 5 8.29e-05 -5.261 0.064
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 215 617 242 590 273 0.00302 309 0.00342 -6.553 0.064
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 527 305 556 276 862 0.00952 1027 0.0114 -16.482 0.063
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 689 143 711 121 1926 0.017 2269 0.0201 -20.715 0.063
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 166 666 191 641 202 0.00335 222 0.00368 -5.277 0.062
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 693 139 715 117 3231 0.0285 3644 0.0322 -19.852 0.061
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 379 453 410 422 527 0.00466 682 0.00603 -16.917 0.060
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 158 674 183 649 187 0.00227 226 0.00275 -8.676 0.059
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 139 693 163 669 159 0.00334 193 0.00405 -10.758 0.057
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 154 678 179 653 169 0.00187 224 0.00248 -11.691 0.057
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 239 593 268 564 388 0.00471 434 0.00528 -7.421 0.057
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 812 20 820 12 9749 0.108 8368 0.0925 49.755 0.055
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 221 611 250 582 300 0.00331 354 0.00391 -9.162 0.053
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 82 750 102 730 98 0.00141 105 0.00151 -2.517 0.052
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 696 136 719 113 1648 0.02 1718 0.0209 -5.813 0.051
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 353 479 386 446 502 0.00444 604 0.00534 -11.847 0.048
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 771 61 787 45 2389 0.0211 2749 0.0243 -19.817 0.045
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 764 68 781 51 2887 0.0191 3106 0.0206 -9.875 0.044
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 707 125 730 102 2974 0.023 3047 0.0236 -3.703 0.044
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 65 767 84 748 70 0.00108 92 0.00142 -8.637 0.044
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 255 577 287 545 438 0.00532 466 0.00567 -4.397 0.043
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 370 462 405 427 518 0.00572 625 0.00691 -13.667 0.039
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 67 765 87 745 78 0.00121 107 0.00166 -10.548 0.038
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 253 579 286 546 309 0.00341 402 0.00445 -14.770 0.038
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 605 227 636 196 2154 0.019 2464 0.0218 -18.008 0.036
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 299 533 334 498 389 0.0043 446 0.00493 -8.632 0.035
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 323 509 359 473 433 0.00478 539 0.00596 -14.560 0.033
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 474 358 510 322 1188 0.0144 1387 0.0169 -18.003 0.033
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 317 515 353 479 501 0.00553 585 0.00647 -11.102 0.033
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 557 275 591 241 1907 0.0211 2210 0.0244 -20.792 0.032
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 583 249 616 216 1044 0.0115 1222 0.0135 -16.329 0.032
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 120 712 147 685 130 0.00158 173 0.0021 -10.907 0.031
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 645 187 675 157 2297 0.0203 2644 0.0234 -19.468 0.031
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 646 186 676 156 2430 0.0215 2796 0.0247 -19.982 0.030
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 530 302 566 266 1563 0.0173 1888 0.0209 -24.045 0.028
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 668 164 697 135 2405 0.0186 2539 0.0197 -7.253 0.028
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 217 615 252 580 269 0.00327 301 0.00366 -6.197 0.025
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 497 335 535 297 838 0.00926 1029 0.0114 -19.043 0.025
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 217 615 253 579 264 0.00379 315 0.00453 -10.456 0.022
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 95 737 122 710 103 0.00148 165 0.00237 -17.475 0.021
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 112 720 141 691 119 0.00158 181 0.0024 -16.036 0.020
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 6 826 14 818 6 0.000113 14 0.000263 -8.861 0.020
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 233 599 271 561 281 0.0031 364 0.00402 -13.851 0.019
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 336 496 378 454 498 0.0055 640 0.00708 -17.897 0.017
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 591 241 629 203 1961 0.0173 2234 0.0198 -16.642 0.015
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 203 629 241 591 229 0.00278 280 0.00341 -10.190 0.015
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 294 538 336 496 365 0.00524 452 0.0065 -14.885 0.015
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 254 578 295 537 352 0.00428 440 0.00535 -14.027 0.014
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 23 809 39 793 23 0.000406 44 0.000778 -12.709 0.014
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 525 307 567 265 1576 0.0157 1699 0.0169 -9.164 0.013
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 495 337 538 294 1391 0.0123 1603 0.0142 -15.204 0.013
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 528 304 570 262 849 0.00938 1054 0.0117 -20.192 0.013
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 333 499 378 454 437 0.00483 577 0.00638 -18.569 0.011
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 510 322 554 278 1124 0.0124 1193 0.0132 -6.480 0.011
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 512 320 556 276 1420 0.0157 1701 0.0188 -21.886 0.011
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 2 830 8 824 2 2.87e-05 8 0.000115 -7.705 0.011
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 414 418 460 372 613 0.00745 717 0.00872 -13.034 0.011
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 524 308 568 264 891 0.0108 1079 0.0131 -19.221 0.010
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 588 244 629 203 1677 0.0185 1944 0.0215 -19.505 0.010
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 182 650 222 610 211 0.00256 267 0.00325 -11.447 0.010
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 440 392 487 345 890 0.00983 1167 0.0129 -25.918 0.009
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 320 512 367 465 493 0.00817 554 0.00919 -10.184 0.008
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 476 356 523 309 1123 0.0112 1327 0.0132 -17.027 0.008
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 483 349 530 302 764 0.00844 952 0.0105 -19.472 0.008
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 113 719 148 684 132 0.00175 183 0.00243 -13.130 0.008
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 277 555 324 508 362 0.004 425 0.0047 -9.760 0.007
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 364 468 413 419 883 0.0107 1019 0.0124 -14.332 0.007
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 451 381 500 332 1028 0.00795 1231 0.00953 -15.480 0.007
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 111 721 147 685 144 0.00175 197 0.0024 -12.594 0.006
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 21 811 39 793 22 0.000389 40 0.000708 -11.429 0.006
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 489 343 538 294 1156 0.0128 1544 0.0171 -31.619 0.006
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 2 830 9 823 2 3.98e-05 9 0.000179 -9.948 0.006
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 262 570 311 521 313 0.00346 434 0.0048 -18.481 0.005
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 420 412 472 360 572 0.00505 773 0.00684 -20.599 0.005
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 354 478 406 426 521 0.00575 595 0.00658 -9.711 0.005
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 510 322 560 272 826 0.01 1027 0.0125 -21.043 0.005
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 171 661 215 617 206 0.0025 267 0.00325 -12.463 0.004
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 68 764 99 733 76 0.00176 119 0.00276 -18.143 0.004
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 182 650 227 605 268 0.00326 346 0.00421 -14.005 0.004
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 189 643 235 597 244 0.00296 312 0.00379 -12.858 0.004
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 364 468 417 415 532 0.00588 661 0.00731 -16.011 0.004
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 184 648 230 602 228 0.00252 303 0.00335 -13.710 0.004
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 542 290 592 240 1819 0.0161 2123 0.0188 -18.976 0.004
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 103 729 141 691 109 0.00144 171 0.00227 -16.494 0.003
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 516 316 568 264 1478 0.0147 1728 0.0172 -18.330 0.003
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 204 628 253 579 300 0.00464 387 0.00599 -16.675 0.003
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 491 341 545 287 1183 0.0131 1480 0.0164 -24.740 0.003
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 256 576 309 523 319 0.00352 458 0.00506 -20.661 0.003
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 563 269 614 218 1025 0.00906 1205 0.0107 -14.850 0.003
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 65 767 98 734 68 0.000901 115 0.00153 -15.240 0.002
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 337 495 393 439 467 0.00516 610 0.00674 -18.453 0.002
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 450 382 506 326 652 0.00648 873 0.00869 -22.628 0.002
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 649 183 694 138 1328 0.0147 1627 0.018 -23.786 0.002
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 183 649 233 599 222 0.00294 267 0.00354 -9.622 0.002
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 55 777 87 745 62 0.000959 107 0.00166 -16.337 0.002
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 566 266 619 213 1033 0.00913 1276 0.0113 -19.455 0.002
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 39 793 67 765 39 0.000517 81 0.00107 -16.216 0.002
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 19 813 40 792 19 0.000315 41 0.00068 -13.351 0.002
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 45 787 75 757 45 0.000646 77 0.00111 -13.199 0.002
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 290 542 348 484 454 0.00501 569 0.00629 -15.374 0.001
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 64 768 99 733 70 0.00108 120 0.00186 -17.142 0.001
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 410 422 470 362 785 0.00867 1037 0.0115 -24.992 0.001
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 331 501 392 440 444 0.00638 584 0.00839 -21.066 0.001
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 515 317 574 258 990 0.012 1246 0.0152 -24.357 0.001
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 302 530 363 469 403 0.00668 529 0.00877 -21.402 0.001
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 526 306 585 247 1045 0.0115 1505 0.0166 -37.931 0.001
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 203 629 260 572 273 0.00362 371 0.00492 -17.739 0.001
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 522 310 583 249 873 0.00964 1092 0.0121 -21.193 0.001
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 3 829 15 817 3 5.3e-05 15 0.000265 -12.438 0.001
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 237 595 298 534 303 0.00368 379 0.00461 -13.049 0.001
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 402 430 469 363 756 0.00919 1005 0.0122 -26.317 0.000
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 168 664 225 607 218 0.00313 298 0.00428 -16.812 0.000
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 620 212 676 156 1375 0.0137 1555 0.0155 -13.928 0.000
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 495 337 561 271 754 0.00833 972 0.0107 -22.332 0.000
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 426 406 495 337 995 0.00879 1215 0.0107 -18.052 0.000
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 134 698 189 643 159 0.00299 229 0.0043 -19.179 0.000
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 446 386 516 316 1030 0.0114 1292 0.0143 -23.333 0.000
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 377 455 448 384 866 0.0115 1125 0.0149 -27.068 0.000
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 355 477 426 406 531 0.00587 717 0.00793 -22.140 0.000
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 64 768 107 725 67 0.000888 121 0.00161 -17.065 0.000
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 454 378 525 307 703 0.00776 914 0.0101 -22.281 0.000
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 180 652 243 589 223 0.0032 312 0.00448 -18.275 0.000
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 439 393 511 321 744 0.00822 958 0.0106 -22.081 0.000
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 176 656 239 593 219 0.00266 313 0.00381 -17.718 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 201 631 267 565 244 0.00323 351 0.00466 -19.898 0.000
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 580 252 646 186 1103 0.011 1330 0.0132 -18.912 0.000
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 136 696 197 635 151 0.00167 257 0.00284 -20.993 0.000
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 423 409 500 332 703 0.00776 907 0.01 -21.626 0.000
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 73 759 123 709 78 0.00103 132 0.00175 -16.343 0.000
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 178 654 248 584 214 0.00236 307 0.00339 -16.874 0.000
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 398 434 479 353 581 0.00834 731 0.0105 -20.210 0.000
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 218 614 301 531 261 0.00548 414 0.0087 -33.005 0.000
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 11 821 44 788 12 0.000225 46 0.000865 -20.715 0.000
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 502 330 595 237 869 0.00768 1083 0.00958 -18.579 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 254 578 357 475 305 0.00404 471 0.00625 -26.654 0.000
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 281 551 387 445 445 0.00737 647 0.0107 -31.020 0.000
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 148 684 241 591 174 0.00192 297 0.00328 -22.663 0.000
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 80 752 160 672 84 0.000928 197 0.00218 -25.533 0.000
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 163 669 269 563 192 0.00212 335 0.0037 -24.811 0.000
BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 0 832 0 832 0 0 0 0 NA 0.000
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 832 0 832 0 11172 0.0987 11253 0.0995 -2.621 0.000
E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 0 832 0 832 0 0 0 0 NA 0.000

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HOMER results

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