Human Analysis


Summary

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Job ID: FF:10189-103D9
Number of target experiments: 1
Number of target CAGE peaks: 1018
Number of target CAGE peak regions: 832
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 832
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:10189-103D9 appendix, adult


Results

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Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 627 205 497 335 1536 0.0367 958 0.0229 86.498 25.827
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 707 125 597 235 1604 0.0182 1251 0.0142 31.734 24.135
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 696 136 586 246 2511 0.0314 1938 0.0242 43.634 23.200
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 561 271 437 395 1000 0.0114 744 0.00846 29.761 21.783
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 663 169 551 281 1458 0.0182 1099 0.0137 36.112 21.670
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 467 365 346 486 787 0.0107 547 0.00746 35.637 20.096
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 718 114 623 209 1781 0.0202 1424 0.0162 30.106 19.884
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 595 237 486 346 1525 0.0173 1200 0.0136 29.821 18.128
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 623 209 518 314 1193 0.0136 908 0.0103 30.017 17.809
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 771 61 700 132 2346 0.0293 1806 0.0226 42.562 17.283
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 712 120 625 207 2806 0.0383 2137 0.0292 50.805 16.831
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 719 113 634 198 3016 0.0411 2293 0.0313 53.064 16.711
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 668 164 577 255 1398 0.0159 1078 0.0123 30.961 15.578
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 364 468 271 561 539 0.00919 356 0.00607 37.637 13.302
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 559 273 467 365 1006 0.0114 816 0.00928 21.088 13.038
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 610 222 523 309 1165 0.0132 932 0.0106 24.217 12.734
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 662 170 581 251 3076 0.0385 2422 0.0303 44.683 12.693
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 597 235 510 322 2314 0.0289 1986 0.0248 24.655 12.470
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 373 459 283 549 496 0.00564 363 0.00413 22.085 12.450
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 304 528 220 612 407 0.00694 292 0.00498 26.092 12.068
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 426 406 336 496 625 0.0071 502 0.00571 17.373 12.050
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 515 317 427 405 852 0.0107 699 0.00874 19.235 11.704
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 794 38 748 84 3208 0.0401 2503 0.0313 47.410 11.565
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 360 472 275 557 545 0.00929 376 0.00641 33.822 11.417
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 782 50 732 100 2747 0.0406 2071 0.0306 54.321 11.347
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 611 221 533 299 1204 0.0137 977 0.0111 23.047 10.691
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 736 96 677 155 3396 0.0425 2787 0.0349 38.867 10.306
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 367 465 287 545 490 0.00557 353 0.00401 23.070 10.228
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 587 245 510 322 1098 0.0125 914 0.0104 19.302 10.088
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 768 64 718 114 2217 0.0252 2033 0.0231 12.996 9.973
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 335 497 258 574 467 0.00796 332 0.00566 28.737 9.917
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 406 426 327 505 741 0.0109 543 0.00803 30.716 9.755
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 243 589 174 658 315 0.00501 201 0.0032 30.099 9.749
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 111 721 64 768 118 0.00188 66 0.00105 23.929 9.111
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 759 73 711 121 4852 0.0662 3867 0.0528 56.281 8.764
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 577 255 508 324 1039 0.0177 865 0.0148 23.032 8.375
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 197 635 139 693 238 0.00271 161 0.00183 19.176 8.318
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 111 721 67 765 125 0.00185 71 0.00105 23.086 8.085
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 736 96 686 146 1893 0.0194 1710 0.0175 13.340 8.057
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 315 517 250 582 406 0.00692 321 0.00548 18.388 7.690
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 748 84 703 129 2229 0.0279 1773 0.0222 36.258 7.415
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 640 192 581 251 1697 0.0231 1488 0.0203 18.904 7.353
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 100 732 61 771 112 0.00255 77 0.00175 17.822 7.156
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 78 754 44 788 84 0.00143 44 0.00075 23.330 7.008
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 538 294 475 357 1006 0.0114 806 0.00917 22.336 6.995
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 776 56 739 93 3191 0.0363 2269 0.0258 61.941 6.952
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 179 653 129 703 203 0.00323 145 0.00231 18.011 6.933
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 435 397 372 460 843 0.0125 645 0.00953 28.199 6.748
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 699 133 650 182 3230 0.0551 2467 0.0421 60.700 6.634
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 338 494 278 554 437 0.00497 375 0.00426 10.113 6.598
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 420 412 359 473 598 0.00748 529 0.00662 9.945 6.441
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 370 462 310 522 524 0.00893 427 0.00728 18.207 6.424
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 335 497 278 554 445 0.00506 393 0.00447 8.280 6.117
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 759 73 722 110 3014 0.0343 2853 0.0324 9.620 6.057
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 224 608 174 658 273 0.00434 224 0.00357 12.239 6.027
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 264 568 212 620 333 0.00416 244 0.00305 18.893 5.872
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 104 728 69 763 116 0.00198 76 0.0013 17.751 5.779
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 548 284 493 339 1015 0.0162 837 0.0133 23.125 5.775
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 428 404 373 459 786 0.0116 619 0.00915 24.269 5.516
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 820 12 803 29 5109 0.0407 4069 0.0324 43.775 5.247
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 136 696 99 733 161 0.00256 118 0.00188 14.795 5.189
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 136 696 99 733 160 0.00291 126 0.00229 12.099 5.189
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 672 160 631 201 1873 0.0234 1590 0.0199 23.717 4.751
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 565 267 518 314 1035 0.0118 928 0.0106 11.122 4.712
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 218 614 176 656 274 0.00467 203 0.00346 19.300 4.711
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 53 779 31 801 55 0.000938 31 0.000529 16.664 4.698
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 105 727 75 757 122 0.00208 92 0.00157 12.093 4.515
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 642 190 601 231 1372 0.0125 1368 0.0124 0.263 4.422
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 34 798 18 814 36 0.000491 18 0.000246 14.656 4.086
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 691 141 656 176 1614 0.0147 1465 0.0133 11.037 4.084
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 722 110 690 142 2209 0.0176 1946 0.0155 15.845 4.079
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 172 660 138 694 222 0.00379 193 0.00329 8.067 3.974
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 8 824 1 831 8 0.000191 1 2.39e-05 31.961 3.949
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 814 18 799 33 8743 0.0994 6937 0.0789 71.326 3.784
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 167 665 135 697 215 0.00342 187 0.00298 7.642 3.719
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 66 766 45 787 69 0.00102 52 0.000769 8.473 3.709
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 237 595 201 631 279 0.00444 231 0.00368 11.806 3.663
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 45 787 28 804 47 0.000908 31 0.000599 11.819 3.597
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 206 626 173 659 269 0.0052 268 0.00518 0.219 3.485
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 702 130 673 159 1693 0.0212 1551 0.0194 12.020 3.354
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 751 81 727 105 4604 0.0733 3755 0.0598 53.361 3.306
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 512 320 476 356 773 0.00879 775 0.00881 -0.267 3.211
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 784 48 765 67 2328 0.0212 2390 0.0217 -3.683 3.200
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 789 43 771 61 2744 0.025 2620 0.0238 6.875 3.162
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 723 109 698 134 1873 0.0234 1799 0.0225 5.794 3.041
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 297 535 264 568 391 0.00533 342 0.00467 9.166 3.026
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 66 766 48 784 68 0.000928 50 0.000682 8.790 3.009
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 142 690 117 715 152 0.00207 143 0.00195 2.581 2.952
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 805 27 791 41 3268 0.0371 3029 0.0344 13.902 2.930
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 777 55 759 73 4786 0.0598 4238 0.053 28.597 2.834
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 18 814 9 823 18 0.000368 16 0.000327 2.085 2.821
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 192 640 165 667 236 0.00402 234 0.00399 0.476 2.810
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 44 788 30 802 47 0.000908 32 0.000619 10.904 2.800
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 73 759 56 776 75 0.00102 60 0.000819 6.681 2.644
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 673 159 648 184 1821 0.0207 1647 0.0187 13.631 2.619
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 135 697 113 719 150 0.00171 128 0.00146 6.125 2.602
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 38 794 26 806 39 0.000621 26 0.000414 9.506 2.523
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 373 459 344 488 554 0.00945 486 0.00829 11.955 2.491
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 766 66 749 83 4606 0.0524 3778 0.043 43.458 2.469
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 48 784 35 797 49 0.000947 35 0.000677 9.729 2.429
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 7 825 2 830 7 0.000143 2 4.09e-05 14.912 2.416
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 771 61 755 77 2453 0.0223 2365 0.0215 5.117 2.396
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 78 754 62 770 85 0.00116 64 0.000873 9.067 2.380
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 323 509 296 536 398 0.00452 375 0.00426 3.732 2.368
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 683 149 661 171 1817 0.0227 1542 0.0193 23.396 2.346
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 714 118 694 138 1650 0.0188 1697 0.0193 -3.696 2.319
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 550 282 524 308 1006 0.0126 905 0.0113 11.153 2.302
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 63 769 49 783 79 0.00162 82 0.00168 -1.434 2.287
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 21 811 13 819 21 0.00043 13 0.000266 9.375 2.186
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 832 0 829 3 6803 0.0696 6740 0.069 2.286 2.081
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 155 677 137 695 177 0.00302 165 0.00281 3.594 1.991
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 25 807 17 815 26 0.000414 17 0.000271 8.129 1.989
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 793 39 782 50 6508 0.0814 5049 0.0632 70.250 1.981
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 667 165 648 184 1468 0.0167 1351 0.0154 10.094 1.972
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 261 571 240 592 312 0.0039 294 0.00368 3.457 1.948
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 625 207 605 227 1169 0.0106 1271 0.0116 -8.181 1.935
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 354 478 332 500 611 0.00833 607 0.00828 0.526 1.912
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 35 797 26 806 37 0.000589 28 0.000446 6.331 1.908
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 204 628 185 647 237 0.0035 218 0.00322 4.617 1.907
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 751 81 737 95 2317 0.0263 2177 0.0248 9.546 1.897
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 556 276 535 297 1159 0.0119 1104 0.0113 4.950 1.890
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 252 580 232 600 302 0.00378 303 0.00379 -0.222 1.880
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 57 775 46 786 62 0.000987 47 0.000748 8.159 1.868
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 11 821 6 826 11 0.000188 6 0.000102 7.848 1.802
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 11 821 6 826 11 0.000263 6 0.000143 9.304 1.802
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 644 188 627 205 1478 0.0168 1298 0.0148 15.866 1.727
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 12 820 7 825 13 0.000251 7 0.000135 9.299 1.725
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 786 46 776 56 2468 0.0281 2712 0.0308 -15.114 1.721
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 96 736 84 748 105 0.00143 88 0.0012 6.253 1.647
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 590 242 573 259 1026 0.0117 1009 0.0115 1.659 1.628
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 810 22 803 29 3665 0.0417 3377 0.0384 15.905 1.625
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 14 818 9 823 14 0.000271 9 0.000174 6.826 1.606
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 41 791 33 799 45 0.000716 35 0.000557 6.294 1.596
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 22 810 16 816 22 0.000375 16 0.000273 5.771 1.579
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 747 85 736 96 2566 0.0292 2330 0.0265 15.605 1.534
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 746 86 735 97 2964 0.0371 2760 0.0345 13.034 1.529
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 34 798 27 805 38 0.000605 28 0.000446 7.039 1.528
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 237 595 222 610 284 0.00323 273 0.0031 2.079 1.508
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 105 727 94 738 108 0.00147 112 0.00153 -1.338 1.492
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 723 109 712 120 2034 0.0231 2086 0.0237 -3.702 1.434
*BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 2 830 0 832 2 3.86e-05 0 0 NA 1.387
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 6 826 3 829 6 9.55e-05 3 4.78e-05 6.400 1.373
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 116 716 106 726 124 0.00169 122 0.00166 0.600 1.354
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 50 782 43 789 52 0.000709 43 0.000587 4.724 1.343
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 211 621 199 633 256 0.00262 240 0.00246 3.073 1.325
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 733 99 724 108 2202 0.0275 2007 0.0251 14.558 1.287
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 753 79 745 87 2583 0.0294 2733 0.0311 -9.283 1.261
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 17 815 13 819 18 0.000327 14 0.000255 4.237 1.236
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 108 724 100 732 123 0.00196 105 0.00167 6.549 1.197
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 314 518 303 529 488 0.00777 489 0.00778 -0.207 1.184
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 467 365 456 376 721 0.00901 748 0.00936 -3.329 1.168
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 465 367 454 378 782 0.0124 772 0.0123 1.310 1.168
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 21 811 17 815 21 0.00043 18 0.000368 2.965 1.166
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 402 430 391 441 579 0.00724 577 0.00722 0.240 1.165
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 438 394 427 405 702 0.00798 736 0.00837 -4.018 1.165
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 3 829 1 831 3 4.77e-05 1 1.59e-05 7.347 1.164
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 23 809 19 813 23 0.000418 19 0.000346 3.635 1.140
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 11 821 8 824 11 0.000225 8 0.000164 4.453 1.131
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 770 62 764 68 2730 0.031 2676 0.0304 3.286 1.127
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 26 806 22 810 26 0.000502 22 0.000425 3.483 1.107
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 183 649 175 657 227 0.00258 216 0.00246 2.341 1.084
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 784 48 779 53 4266 0.0533 3458 0.0433 46.503 1.077
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 299 533 290 542 480 0.006 495 0.00619 -2.277 1.076
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 152 680 145 687 170 0.00213 163 0.00204 1.792 1.048
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 39 793 35 797 41 0.000559 35 0.000478 3.481 1.020
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 765 67 760 72 2722 0.034 2654 0.0332 4.383 1.017
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 829 3 827 5 4887 0.05 4725 0.0484 7.164 1.013
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 90 742 85 747 100 0.00136 92 0.00126 2.863 0.982
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 90 742 85 747 98 0.00156 94 0.0015 1.517 0.982
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 375 457 368 464 516 0.00469 535 0.00487 -2.361 0.958
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 398 434 391 441 559 0.00635 574 0.00653 -2.021 0.957
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 422 410 415 417 668 0.00911 667 0.0091 0.095 0.956
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 7 825 5 827 7 0.000119 5 8.53e-05 3.403 0.950
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 28 804 25 807 28 0.000541 25 0.000483 2.442 0.941
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 9 823 7 825 9 0.000164 7 0.000127 2.972 0.913
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 36 796 33 799 37 0.000673 35 0.000637 1.322 0.909
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 96 736 92 740 108 0.00172 100 0.00159 2.968 0.896
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 102 730 98 734 110 0.0015 102 0.00139 2.718 0.890
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 624 208 619 213 1209 0.0137 1292 0.0147 -7.403 0.890
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 521 311 516 316 904 0.0113 962 0.012 -6.283 0.868
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 763 69 760 72 2392 0.0218 2800 0.0255 -22.148 0.844
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 19 813 17 815 23 0.000366 18 0.000287 4.372 0.836
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 565 267 561 271 913 0.0114 1021 0.0128 -11.325 0.827
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 93 739 90 742 99 0.0018 99 0.0018 -0.028 0.826
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 482 350 478 354 870 0.00989 973 0.0111 -10.541 0.819
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 696 136 693 139 2363 0.0295 2116 0.0265 17.984 0.804
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 36 796 34 798 39 0.000532 35 0.000478 2.310 0.795
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 54 778 52 780 58 0.00105 55 0.001 1.590 0.776
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 341 491 339 493 449 0.00408 498 0.00453 -6.255 0.734
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 3 829 2 830 3 5.46e-05 2 3.64e-05 2.737 0.693
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 770 62 769 63 2750 0.0313 2916 0.0332 -9.953 0.693
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 5 827 4 828 5 7.39e-05 4 5.91e-05 1.730 0.693
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 580 252 579 253 1000 0.00909 1132 0.0103 -11.194 0.693
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 829 3 828 4 8878 0.0605 7436 0.0507 41.949 0.693
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 23 809 22 810 23 0.000366 23 0.000366 -0.035 0.693
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 492 340 492 340 939 0.0107 995 0.0113 -5.688 0.654
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 686 146 686 146 2195 0.02 2311 0.021 -6.952 0.643
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 74 758 74 758 78 0.00115 84 0.00124 -2.389 0.627
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 354 478 355 477 478 0.00761 468 0.00745 1.699 0.617
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 178 654 179 653 211 0.00408 215 0.00416 -1.158 0.602
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 460 372 462 370 816 0.0102 790 0.00988 3.042 0.582
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 352 480 354 478 462 0.00683 503 0.00744 -6.652 0.581
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 347 485 349 483 452 0.00565 449 0.00562 0.437 0.581
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 86 746 87 745 91 0.00103 98 0.00111 -2.265 0.573
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 15 817 15 817 15 0.000256 15 0.000256 -0.039 0.557
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 131 701 133 699 142 0.00178 151 0.00189 -2.459 0.545
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 130 702 132 700 146 0.00299 146 0.00299 -0.029 0.545
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 49 783 50 782 51 0.00087 52 0.000887 -0.566 0.541
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 563 269 566 266 980 0.0123 1059 0.0132 -8.150 0.539
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 46 786 47 785 46 0.000732 49 0.00078 -1.633 0.537
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 400 432 404 428 598 0.0102 664 0.0113 -10.018 0.516
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 523 309 527 305 873 0.0109 956 0.012 -8.999 0.510
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 769 63 771 61 2826 0.0225 3353 0.0267 -24.465 0.494
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 61 771 63 769 66 0.00113 68 0.00116 -0.967 0.494
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 6 826 6 826 6 0.000116 6 0.000116 -0.053 0.489
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 22 810 23 809 23 0.000366 24 0.000382 -0.798 0.480
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 22 810 23 809 22 0.000425 24 0.000464 -1.716 0.480
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 44 788 46 786 45 0.000767 49 0.000836 -2.242 0.466
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 82 750 85 747 84 0.00181 87 0.00188 -1.431 0.465
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 18 814 19 813 19 0.000259 19 0.000259 -0.039 0.462
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 324 508 330 502 416 0.00473 467 0.00531 -7.515 0.450
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 544 288 550 282 908 0.0114 992 0.0124 -8.944 0.444
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 3 829 3 829 3 5.8e-05 3 5.8e-05 -0.073 0.421
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 188 644 194 638 238 0.00189 230 0.00183 1.369 0.418
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 48 784 51 781 50 0.000796 56 0.000891 -3.029 0.415
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 70 762 74 758 79 0.00153 85 0.00164 -2.713 0.403
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 368 464 376 456 543 0.0037 626 0.00427 -8.173 0.398
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 213 619 220 612 268 0.00305 295 0.00335 -5.008 0.397
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 689 143 695 137 1720 0.0196 1799 0.0205 -6.005 0.390
E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 2 830 2 830 2 3.64e-05 2 3.64e-05 -0.091 0.374
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 400 432 409 423 575 0.00654 626 0.00712 -6.504 0.374
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 490 342 499 333 772 0.00702 788 0.00717 -1.654 0.369
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 70 762 75 757 75 0.00136 80 0.00146 -2.265 0.358
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 190 642 198 634 238 0.00298 245 0.00306 -1.515 0.358
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 27 805 30 802 28 0.000446 30 0.000478 -1.399 0.350
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 14 818 16 816 14 0.000255 16 0.000291 -2.037 0.343
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 605 227 614 218 1696 0.027 1757 0.028 -5.586 0.342
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 111 721 118 714 131 0.00313 127 0.00303 1.599 0.335
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 443 389 454 378 666 0.00681 754 0.00772 -9.687 0.325
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 97 735 104 728 107 0.0017 121 0.00193 -4.794 0.320
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 794 38 798 34 2985 0.0305 3325 0.034 -18.064 0.320
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 21 811 24 808 23 0.000418 25 0.000455 -1.633 0.319
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 316 516 327 505 406 0.00461 429 0.00488 -3.552 0.319
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 314 518 325 507 426 0.00629 431 0.00637 -0.906 0.318
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 11 821 13 819 11 0.000213 13 0.000251 -2.326 0.314
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 181 651 191 641 198 0.00248 234 0.00293 -7.844 0.299
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 811 21 814 18 3697 0.0336 3792 0.0345 -4.510 0.299
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 494 338 506 326 798 0.00998 879 0.011 -9.152 0.298
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 771 61 777 55 3573 0.0325 4701 0.0428 -47.630 0.288
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 1 831 1 831 1 2.27e-05 1 2.27e-05 -0.113 0.287
SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 1 831 1 831 1 1.82e-05 1 1.82e-05 -0.126 0.287
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 831 1 831 1 7214 0.0738 6749 0.0691 17.497 0.287
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 234 598 246 586 310 0.00423 337 0.0046 -5.138 0.276
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 560 272 573 259 944 0.00966 1036 0.0106 -8.661 0.262
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 43 789 49 783 48 0.000764 56 0.000891 -4.030 0.257
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 12 820 15 817 12 0.000232 15 0.00029 -3.231 0.247
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 392 440 407 425 616 0.0105 639 0.0109 -3.585 0.244
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 338 494 354 478 473 0.00538 588 0.00669 -15.080 0.222
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 488 344 504 328 890 0.0111 951 0.0119 -6.643 0.220
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 327 505 343 489 454 0.00516 519 0.0059 -9.082 0.220
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 509 323 525 307 807 0.00917 909 0.0103 -10.794 0.217
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 150 682 163 669 176 0.0036 189 0.00387 -4.050 0.211
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 740 92 750 82 3149 0.0251 3472 0.0276 -14.768 0.210
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 357 475 374 458 543 0.00864 577 0.00919 -5.359 0.207
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 318 514 335 497 409 0.00604 454 0.00671 -7.675 0.202
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 160 672 174 658 197 0.00291 234 0.00346 -8.765 0.198
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 539 293 556 276 1241 0.0212 1355 0.0231 -12.192 0.194
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 35 797 42 790 36 0.000614 44 0.00075 -4.701 0.193
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 202 630 218 614 243 0.00331 261 0.00356 -3.896 0.185
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 98 734 110 722 105 0.00143 121 0.00165 -5.070 0.183
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 760 72 770 62 4066 0.0462 5043 0.0573 -44.891 0.175
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 20 812 26 806 20 0.000386 26 0.000503 -4.884 0.160
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 9 823 13 819 9 0.000174 13 0.000251 -4.613 0.153
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 162 670 179 653 183 0.00229 207 0.00259 -5.567 0.148
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 720 112 734 98 1773 0.0222 1844 0.0231 -5.605 0.144
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 786 46 795 37 2639 0.024 2779 0.0253 -7.668 0.139
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 360 472 382 450 517 0.00705 533 0.00727 -2.446 0.137
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 787 45 796 36 4776 0.038 5439 0.0433 -24.391 0.136
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 585 247 605 227 1230 0.014 1421 0.0162 -16.201 0.136
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 219 613 239 593 269 0.00245 280 0.00255 -1.890 0.133
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 722 110 737 95 2586 0.0235 3638 0.0331 -50.229 0.124
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 268 564 290 542 390 0.00488 435 0.00544 -7.208 0.123
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 737 95 751 81 3242 0.0295 3992 0.0363 -34.267 0.123
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 4 828 7 825 4 6.82e-05 7 0.000119 -4.444 0.119
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 415 417 439 393 681 0.00774 769 0.00874 -10.116 0.117
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 6 826 10 822 6 0.000109 10 0.000182 -5.103 0.110
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 165 667 185 647 186 0.00233 219 0.00274 -7.433 0.109
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 404 428 429 403 706 0.00963 820 0.0112 -13.909 0.107
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 796 36 805 27 5720 0.0455 6989 0.0556 -41.408 0.105
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 12 820 18 814 12 0.000191 18 0.000287 -5.329 0.103
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 86 746 102 730 96 0.00142 108 0.0016 -4.193 0.099
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 38 794 49 783 42 0.000764 52 0.000946 -5.577 0.098
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 15 817 22 810 15 0.00029 24 0.000464 -7.607 0.096
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 705 127 723 109 3011 0.0274 3813 0.0347 -37.453 0.095
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 711 121 729 103 3041 0.0242 3819 0.0304 -33.886 0.090
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 414 418 441 391 669 0.00836 729 0.00912 -7.442 0.089
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 239 593 264 568 280 0.00414 367 0.00543 -16.449 0.086
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 687 145 707 125 2189 0.0199 2593 0.0236 -22.764 0.085
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 55 777 69 763 63 0.000931 72 0.00106 -3.854 0.084
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 354 478 382 450 490 0.00446 596 0.00542 -12.345 0.079
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 736 96 753 79 3114 0.0283 4282 0.039 -51.563 0.078
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 700 132 720 112 2699 0.0307 3394 0.0386 -38.542 0.076
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 548 284 575 257 1198 0.0109 1451 0.0132 -18.953 0.074
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 374 458 403 429 570 0.00518 711 0.00647 -15.038 0.073
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 74 758 91 741 78 0.00151 101 0.00195 -9.471 0.072
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 82 750 100 732 98 0.00145 108 0.0016 -3.499 0.070
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 2 830 5 827 2 4.09e-05 5 0.000102 -5.748 0.064
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 242 590 270 562 312 0.00532 371 0.00633 -11.934 0.064
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 657 175 681 151 1671 0.0152 1905 0.0173 -15.346 0.063
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 206 626 233 599 245 0.00362 308 0.00455 -13.002 0.061
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 71 761 89 743 73 0.00116 99 0.00158 -9.811 0.059
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 722 110 742 90 3320 0.0302 4189 0.0381 -38.787 0.058
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 722 110 742 90 2650 0.0241 3134 0.0285 -24.869 0.058
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 674 158 698 134 2375 0.0216 3012 0.0274 -33.345 0.055
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 328 504 360 472 490 0.00446 573 0.00521 -9.864 0.052
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 593 239 622 210 1304 0.0133 1500 0.0154 -15.346 0.050
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 209 623 238 594 273 0.0031 318 0.00362 -8.023 0.050
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 26 806 38 794 26 0.000502 38 0.000735 -8.057 0.050
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 258 574 289 543 352 0.0044 413 0.00517 -10.012 0.049
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 556 276 587 245 1610 0.0165 2025 0.0207 -28.008 0.046
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 635 197 663 169 1284 0.0131 1406 0.0144 -9.877 0.044
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 698 134 722 110 1903 0.0173 2501 0.0228 -34.264 0.042
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 486 346 520 312 995 0.00905 1215 0.0111 -17.991 0.040
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 662 170 689 143 1506 0.0154 1646 0.0168 -10.489 0.040
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 12 820 21 811 12 0.000205 21 0.000358 -7.641 0.039
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 592 240 623 209 1411 0.016 1861 0.0212 -33.391 0.039
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 671 161 698 134 2473 0.0225 3298 0.03 -41.314 0.037
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 178 654 208 624 206 0.00281 267 0.00364 -12.984 0.037
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 529 303 563 269 1052 0.0132 1152 0.0144 -9.889 0.036
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 756 76 775 57 4271 0.034 5119 0.0407 -32.087 0.036
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 703 129 728 104 2515 0.02 2927 0.0233 -20.442 0.034
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 20 812 32 800 20 0.000364 32 0.000582 -8.517 0.034
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 75 757 97 735 81 0.0011 111 0.00151 -9.897 0.032
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 527 305 562 270 875 0.00995 954 0.0108 -8.173 0.032
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 6 826 13 819 6 0.000116 13 0.000251 -8.044 0.032
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 192 640 224 608 267 0.00364 314 0.00428 -9.238 0.031
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 548 284 583 249 914 0.0104 1127 0.0128 -20.235 0.030
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 532 300 568 264 920 0.0105 1149 0.0131 -21.546 0.028
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 445 387 483 349 680 0.0085 825 0.0103 -16.869 0.027
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 210 622 244 588 271 0.00339 314 0.00393 -8.093 0.027
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 158 674 189 643 195 0.00377 242 0.00468 -12.516 0.027
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 476 356 514 318 961 0.012 1201 0.015 -23.187 0.026
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 759 73 779 53 2666 0.0182 2942 0.0201 -12.644 0.026
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 699 133 726 106 1698 0.0154 1851 0.0168 -10.193 0.025
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 375 457 414 418 644 0.00732 784 0.00891 -15.919 0.025
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 56 776 77 755 58 0.000791 79 0.00108 -8.215 0.023
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 577 255 613 219 1226 0.0153 1448 0.0181 -19.576 0.022
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 192 640 227 605 238 0.00352 311 0.0046 -14.989 0.021
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 114 718 143 689 125 0.00156 154 0.00193 -7.784 0.021
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 281 551 320 512 443 0.00604 543 0.00741 -14.955 0.021
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 248 584 286 546 299 0.0034 383 0.00436 -13.632 0.020
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 2 830 7 825 2 3.18e-05 8 0.000127 -7.988 0.019
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 2 830 7 825 2 3.64e-05 7 0.000127 -7.610 0.019
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 31 801 48 784 34 0.000696 50 0.00102 -9.631 0.019
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 331 501 373 459 573 0.00586 689 0.00705 -13.339 0.017
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 536 296 576 256 1160 0.0132 1330 0.0151 -14.899 0.017
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 649 183 683 149 1665 0.0151 2022 0.0184 -22.713 0.016
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 437 395 480 352 978 0.01 1229 0.0126 -21.656 0.015
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 194 638 232 600 246 0.0028 313 0.00356 -12.025 0.014
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 78 754 105 727 86 0.00127 112 0.00166 -8.891 0.014
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 20 812 35 797 20 0.000386 36 0.000696 -11.026 0.014
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 650 182 685 147 2300 0.0209 2806 0.0255 -27.425 0.013
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 501 331 544 288 812 0.00923 964 0.011 -15.606 0.013
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 168 664 205 627 188 0.00321 232 0.00396 -11.239 0.013
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 256 576 298 534 374 0.00553 484 0.00715 -18.126 0.013
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 253 579 295 537 384 0.00524 498 0.0068 -17.789 0.013
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 486 346 531 301 1028 0.00935 1187 0.0108 -13.164 0.010
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 343 489 389 443 481 0.00547 545 0.0062 -8.730 0.010
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 40 792 62 770 40 0.000773 63 0.00122 -11.980 0.009
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 481 351 527 305 725 0.00824 878 0.00998 -16.449 0.009
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 437 395 484 348 705 0.00721 868 0.00888 -16.708 0.009
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 608 224 649 183 2092 0.0214 2705 0.0277 -35.915 0.008
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 1 831 6 826 1 2.05e-05 6 0.000123 -8.711 0.008
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 76 756 106 726 83 0.000943 125 0.00142 -11.913 0.007
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 711 121 743 89 2185 0.0199 2781 0.0253 -32.433 0.007
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 120 712 156 676 136 0.00186 191 0.00261 -13.830 0.007
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 199 633 243 589 245 0.00306 331 0.00414 -15.738 0.006
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 653 179 693 139 2346 0.0213 3195 0.0291 -43.171 0.005
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 348 484 399 433 553 0.00754 654 0.00892 -13.779 0.005
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 451 381 502 330 900 0.00818 1055 0.0096 -13.601 0.005
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 659 173 699 133 1561 0.016 2091 0.0214 -35.199 0.005
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 163 669 206 626 217 0.00321 296 0.00438 -16.621 0.005
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 119 713 158 674 143 0.00244 188 0.00321 -12.759 0.004
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 636 196 679 153 2089 0.019 2618 0.0238 -29.651 0.004
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 550 282 599 233 1426 0.013 1684 0.0153 -17.966 0.004
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 107 725 145 687 120 0.00136 178 0.00202 -13.787 0.004
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 514 318 565 267 1230 0.014 1707 0.0194 -36.916 0.004
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 150 682 194 638 168 0.00363 230 0.00497 -17.894 0.003
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 222 610 272 560 323 0.00441 386 0.00527 -11.169 0.003
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 620 212 666 166 1802 0.0164 2316 0.0211 -30.583 0.003
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 610 222 657 175 1669 0.019 2251 0.0256 -39.351 0.003
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 334 498 389 443 454 0.00774 539 0.00919 -14.283 0.003
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 646 186 690 142 1353 0.0154 1533 0.0174 -14.715 0.003
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 20 812 40 792 21 0.000382 41 0.000746 -12.525 0.003
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 566 266 617 215 1008 0.00917 1241 0.0113 -18.853 0.002
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 198 634 248 584 239 0.00272 314 0.00357 -13.436 0.002
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 464 368 520 312 924 0.0116 1130 0.0141 -20.513 0.002
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 70 762 105 727 81 0.00129 132 0.0021 -16.651 0.002
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 126 706 170 662 143 0.00163 194 0.00221 -11.618 0.002
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 400 432 458 374 585 0.00864 715 0.0106 -17.661 0.002
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 627 205 676 156 2271 0.0155 3059 0.0209 -35.318 0.001
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 67 765 103 729 75 0.00119 124 0.00197 -16.506 0.001
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 165 667 216 616 204 0.00232 283 0.00322 -14.901 0.001
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 427 405 488 344 615 0.00559 750 0.00682 -14.024 0.001
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 556 276 612 220 1639 0.0186 2293 0.0261 -43.817 0.001
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 496 336 557 275 1263 0.0172 1697 0.0232 -36.977 0.001
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 19 813 42 790 20 0.000386 43 0.000831 -14.494 0.001
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 562 270 620 212 1625 0.0166 1969 0.0202 -23.545 0.001
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 633 199 685 147 2162 0.0197 2908 0.0265 -39.710 0.001
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 457 375 521 311 776 0.00882 989 0.0112 -21.579 0.001
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 413 419 478 354 911 0.0114 1301 0.0163 -36.200 0.001
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 513 319 575 257 1256 0.0157 1652 0.0207 -32.702 0.001
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 352 480 418 414 755 0.00944 978 0.0122 -23.836 0.000
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 71 761 112 720 79 0.00126 139 0.00221 -19.087 0.000
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 548 284 609 223 1414 0.0129 1947 0.0177 -34.518 0.000
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 546 286 608 224 1182 0.0134 1591 0.0181 -32.769 0.000
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 549 283 611 221 1086 0.0136 1460 0.0183 -32.810 0.000
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 288 544 354 478 460 0.00523 599 0.00681 -18.054 0.000
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 98 734 146 686 116 0.00211 173 0.00315 -17.388 0.000
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 375 457 445 387 550 0.00625 749 0.00852 -23.127 0.000
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 600 232 660 172 1666 0.0133 1896 0.0151 -14.128 0.000
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 340 492 410 422 535 0.00608 710 0.00807 -20.887 0.000
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 492 340 560 272 1055 0.012 1557 0.0177 -40.636 0.000
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 221 611 286 546 298 0.00339 396 0.0045 -15.637 0.000
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 79 753 125 707 97 0.00154 145 0.00231 -14.958 0.000
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 65 767 108 724 74 0.00143 120 0.00232 -17.359 0.000
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 125 707 180 652 163 0.00204 247 0.00309 -17.780 0.000
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 168 664 229 603 222 0.00278 338 0.00423 -20.998 0.000
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 546 286 612 220 1645 0.0206 2205 0.0276 -40.166 0.000
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 229 603 296 536 274 0.00592 421 0.0091 -31.405 0.000
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 62 770 105 727 65 0.000887 110 0.0015 -14.899 0.000
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 294 538 365 467 366 0.00416 485 0.00551 -17.165 0.000
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 459 373 533 299 805 0.00915 1042 0.0118 -23.396 0.000
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 528 304 599 233 1002 0.0114 1694 0.0193 -53.731 0.000
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 331 501 409 423 444 0.00656 594 0.00878 -22.324 0.000
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 484 348 560 272 764 0.00868 1015 0.0115 -25.098 0.000
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 271 561 347 485 441 0.00551 629 0.00787 -24.993 0.000
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 558 274 630 202 1519 0.0138 1990 0.0181 -30.184 0.000
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 2 830 17 815 2 3.64e-05 17 0.000309 -14.588 0.000
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 539 293 613 219 1404 0.016 2038 0.0232 -44.984 0.000
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 108 724 169 663 130 0.00192 212 0.00313 -20.363 0.000
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 205 627 280 552 280 0.00318 410 0.00466 -20.378 0.000
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 136 696 203 629 187 0.00255 262 0.00358 -16.107 0.000
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 30 802 69 763 31 0.000423 73 0.000996 -17.062 0.000
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 569 263 644 188 1787 0.0162 2556 0.0233 -43.581 0.000
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 182 650 259 573 240 0.00273 387 0.0044 -23.709 0.000
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 583 249 659 173 1887 0.0214 2684 0.0305 -49.465 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 16 816 49 783 16 0.000273 54 0.000921 -20.062 0.000
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 507 325 591 241 1109 0.0113 1610 0.0165 -37.814 0.000
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 522 310 606 226 1361 0.0124 1973 0.0179 -39.369 0.000
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 377 455 467 365 566 0.00643 816 0.00928 -27.840 0.000
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 245 587 332 500 385 0.00481 580 0.00725 -26.984 0.000
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 201 631 284 548 283 0.00354 418 0.00523 -21.986 0.000
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 515 317 601 231 1185 0.0135 1919 0.0218 -53.620 0.000
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 462 370 553 279 1092 0.00869 1474 0.0117 -26.519 0.000
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 147 685 227 605 166 0.00189 272 0.00309 -20.382 0.000
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 427 405 523 309 795 0.00904 1237 0.0141 -40.063 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 255 577 349 483 311 0.00424 481 0.00656 -26.970 0.000
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 143 689 224 608 188 0.00235 302 0.00378 -21.825 0.000
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 464 368 561 271 924 0.0105 1454 0.0165 -44.363 0.000
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 321 511 422 410 432 0.00491 606 0.00689 -22.461 0.000
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 430 402 531 301 759 0.00949 1255 0.0157 -46.845 0.000
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 11 821 49 783 11 0.0002 52 0.000946 -22.777 0.000
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 316 516 430 402 514 0.00876 801 0.0137 -39.585 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 178 654 285 547 204 0.00278 362 0.00494 -28.865 0.000
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 448 384 567 265 950 0.00864 1497 0.0136 -40.301 0.000
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 161 671 269 563 182 0.00207 328 0.00373 -25.566 0.000
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 101 731 196 636 106 0.0012 232 0.00264 -26.218 0.000
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 377 455 508 324 691 0.0118 1265 0.0216 -63.235 0.000
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 177 655 297 535 196 0.00223 372 0.00423 -28.943 0.000
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 397 435 531 301 881 0.012 1445 0.0197 -51.956 0.000
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 206 626 338 494 297 0.00473 539 0.00858 -39.202 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 195 637 344 488 262 0.00357 552 0.00753 -42.949 0.000
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 831 1 832 0 7867 0.0537 7610 0.0519 7.324 0.000
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 0 832 4 828 0 0 4 9.1e-05 -9.002 0.000
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 832 0 832 0 11093 0.101 11387 0.104 -8.352 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 168 664 334 498 220 0.003 501 0.00684 -43.666 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 117 715 262 570 135 0.00184 337 0.0046 -38.231 0.000

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HOMER results

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