Human Analysis


Summary

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Job ID: FF:10830-111D2
Number of target experiments: 1
Number of target CAGE peaks: 773
Number of target CAGE peak regions: 566
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 566
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:10830-111D2 acute myeloid leukemia (FAB M4) cell line:FKH-1


Results

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Click column headers to sort by that column

Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 497 69 403 163 1171 0.0209 877 0.0157 33.025 26.850
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 443 123 346 220 1120 0.0381 709 0.0242 71.384 22.239
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 524 42 453 113 1416 0.0229 1151 0.0187 24.766 21.647
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 498 68 418 148 1251 0.0203 911 0.0148 35.728 20.930
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 91 475 31 535 97 0.0022 34 0.000772 40.362 19.285
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 413 153 332 234 758 0.0135 580 0.0104 24.509 15.199
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 471 95 400 166 1047 0.017 793 0.0129 28.561 14.872
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 500 66 437 129 2028 0.0361 1619 0.0289 34.000 14.624
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 443 123 369 197 912 0.0148 675 0.011 28.868 14.216
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 532 34 483 83 1664 0.0297 1280 0.0228 35.820 13.781
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 336 230 258 308 506 0.0082 397 0.00644 17.250 13.018
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 449 117 380 186 921 0.0149 659 0.0107 32.309 12.968
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 521 45 470 96 2447 0.0476 2021 0.0393 33.250 12.789
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 429 137 363 203 1162 0.0188 904 0.0147 27.183 11.329
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 492 74 439 127 2669 0.0476 2297 0.041 26.046 10.626
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 197 369 134 432 252 0.00449 160 0.00286 24.072 10.614
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 260 306 197 369 348 0.00564 275 0.00446 13.861 9.373
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 335 231 271 295 576 0.0112 429 0.00835 24.567 9.366
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 433 133 375 191 882 0.0143 684 0.0111 23.939 9.354
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 510 56 466 100 2223 0.0432 1848 0.036 30.547 9.242
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 442 124 386 180 917 0.0149 725 0.0118 22.545 9.118
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 421 145 364 202 816 0.0132 647 0.0105 20.991 8.806
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 538 28 505 61 4010 0.078 3504 0.0682 30.364 8.622
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 527 39 490 76 2751 0.049 2197 0.0392 39.746 8.618
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 274 292 214 352 368 0.00596 317 0.00514 8.990 8.533
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 277 289 218 348 373 0.00604 288 0.00467 15.783 8.285
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 106 460 64 502 113 0.0022 72 0.0014 16.682 8.085
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 338 228 280 286 572 0.0111 462 0.00899 17.688 8.016
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 239 327 183 383 333 0.00647 262 0.0051 15.138 7.937
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 452 114 404 162 2152 0.0384 1939 0.0346 16.112 7.489
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 395 171 342 224 749 0.0121 626 0.0102 15.501 7.443
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 199 367 148 418 247 0.006 188 0.00458 16.611 7.377
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 160 406 113 453 194 0.0044 131 0.00298 20.542 7.288
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 545 21 519 47 2268 0.0404 1953 0.0349 23.841 7.139
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 538 28 511 55 2357 0.0382 1825 0.0296 39.759 6.559
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 367 199 317 249 577 0.00935 488 0.00792 12.680 6.543
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 557 9 539 27 3258 0.0581 2749 0.0491 32.750 6.377
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 240 326 192 374 336 0.00817 255 0.00621 19.601 6.213
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 275 291 227 339 466 0.0106 376 0.00854 17.323 6.011
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 165 401 123 443 242 0.00667 175 0.00483 20.835 5.973
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 219 347 175 391 282 0.00503 215 0.00384 15.097 5.619
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 504 62 472 94 2626 0.0638 2124 0.0517 43.040 5.603
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 133 433 96 470 150 0.00292 108 0.0021 13.942 5.567
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 260 306 215 351 390 0.00948 269 0.00655 28.553 5.519
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 533 33 509 57 1896 0.0399 1681 0.0355 19.030 5.189
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 45 521 24 542 48 0.000933 24 0.000467 16.910 5.078
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 467 99 433 133 1422 0.0276 1200 0.0234 22.280 4.893
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 285 281 244 322 478 0.00852 386 0.00689 15.477 4.759
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 153 413 118 448 213 0.00518 149 0.00363 20.255 4.723
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 33 533 16 550 34 0.000826 17 0.000414 15.908 4.678
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 115 451 84 482 131 0.00255 93 0.00181 13.593 4.656
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 560 6 548 18 3340 0.0379 2751 0.0312 29.971 4.544
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 380 186 343 223 667 0.0108 612 0.00993 6.948 4.348
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 101 465 73 493 113 0.00256 91 0.00207 8.570 4.348
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 342 224 304 262 634 0.0134 520 0.011 17.994 4.333
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 121 445 91 475 146 0.00237 108 0.00175 11.505 4.305
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 143 423 111 455 169 0.00411 128 0.00311 13.977 4.302
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 498 68 471 95 1296 0.0189 1268 0.0185 2.228 4.287
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 75 491 51 515 80 0.00168 56 0.00118 11.507 4.219
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 343 223 306 260 689 0.0145 605 0.0128 12.257 4.184
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 537 29 518 48 3856 0.0875 3217 0.0731 43.452 4.104
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 395 171 361 205 680 0.011 655 0.0106 2.987 3.984
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 185 381 152 414 237 0.00538 193 0.00438 11.788 3.978
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 513 53 490 76 1585 0.0282 1393 0.0249 17.092 3.930
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 174 392 143 423 228 0.00443 179 0.00348 12.627 3.752
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 418 148 387 179 813 0.0132 757 0.0123 6.347 3.708
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 52 514 34 532 64 0.00187 35 0.00102 20.739 3.576
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 477 89 452 114 1169 0.0208 1014 0.0181 16.131 3.461
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 269 297 237 329 443 0.0108 363 0.00883 16.216 3.445
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 510 56 489 77 1478 0.0239 1457 0.0236 1.589 3.433
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 483 83 459 107 1399 0.0249 1119 0.02 27.867 3.394
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 64 502 45 521 74 0.00144 49 0.000954 12.316 3.362
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 7 559 1 565 7 0.000147 1 2.11e-05 21.475 3.362
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 274 292 243 323 365 0.00887 326 0.00793 8.291 3.305
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 60 506 42 524 65 0.00137 44 0.000928 11.359 3.254
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 554 12 543 23 5103 0.0909 4247 0.0758 44.977 3.163
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 74 492 55 511 78 0.00126 66 0.00107 4.616 3.080
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 311 255 282 284 590 0.0124 520 0.011 11.003 3.041
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 29 537 17 549 30 0.000729 18 0.000438 10.897 3.029
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 562 4 555 11 6726 0.109 5539 0.0899 52.493 2.847
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 140 426 117 449 156 0.00329 138 0.00291 5.460 2.826
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 88 478 69 497 103 0.0025 86 0.00209 7.040 2.801
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 282 284 255 311 499 0.00889 456 0.00814 6.598 2.799
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 46 520 32 534 48 0.00117 32 0.000779 10.899 2.759
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 556 10 547 19 2508 0.0406 2426 0.0394 5.149 2.726
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 24 542 14 552 25 0.000486 18 0.00035 5.659 2.684
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 205 361 181 385 270 0.00612 262 0.00595 1.763 2.595
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 140 426 119 447 191 0.00433 152 0.00345 11.775 2.545
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 188 378 165 401 240 0.00389 201 0.00326 8.635 2.538
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 46 520 33 533 51 0.00132 33 0.000857 12.477 2.518
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 33 533 22 544 33 0.000802 22 0.000535 9.027 2.487
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 75 491 59 507 82 0.00239 69 0.00202 6.580 2.481
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 133 433 113 453 163 0.00238 139 0.00203 6.047 2.460
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 429 137 408 158 1064 0.019 899 0.016 18.246 2.433
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 150 416 130 436 174 0.00395 151 0.00343 6.937 2.351
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 408 158 387 179 738 0.0108 694 0.0101 4.919 2.335
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 215 351 193 373 286 0.00463 240 0.00389 9.325 2.335
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 31 535 21 545 32 0.000622 25 0.000487 4.795 2.298
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 522 44 509 57 1539 0.0199 1558 0.0202 -1.532 2.250
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 5 561 1 565 5 0.00017 1 3.41e-05 18.203 2.219
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 536 30 525 41 3647 0.0591 2971 0.0482 39.929 2.207
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 114 452 97 469 128 0.00228 109 0.00195 5.976 2.198
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 37 529 27 539 38 0.000739 32 0.000623 3.621 2.093
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 23 543 15 551 23 0.000522 15 0.000341 7.671 2.088
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 111 455 95 471 121 0.00274 112 0.00254 3.117 2.088
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 13 553 7 559 13 0.000379 7 0.000204 9.556 2.044
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 95 471 81 485 107 0.00243 88 0.002 7.519 1.944
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 402 164 385 181 817 0.0119 865 0.0126 -5.050 1.892
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 300 266 282 284 563 0.00912 513 0.00832 6.901 1.858
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 422 144 406 160 885 0.0129 813 0.0119 7.493 1.850
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 93 473 80 486 103 0.0025 94 0.00229 3.532 1.828
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 96 470 83 483 108 0.00192 101 0.0018 2.250 1.807
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 511 55 500 66 1603 0.026 1594 0.0259 0.544 1.784
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 17 549 11 555 17 0.000386 11 0.00025 6.708 1.775
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 533 33 524 42 1851 0.024 1760 0.0228 6.035 1.775
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 350 216 334 232 653 0.00952 638 0.00932 1.679 1.709
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 76 490 65 501 83 0.00269 70 0.00227 6.888 1.692
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 317 249 301 265 569 0.00553 525 0.00511 4.627 1.686
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 38 528 30 536 42 0.00109 32 0.000831 7.016 1.657
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 72 494 62 504 78 0.00202 67 0.00174 5.317 1.590
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 548 18 542 24 2213 0.0359 2169 0.0352 2.832 1.532
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 308 258 294 272 474 0.00845 463 0.00826 1.597 1.517
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 429 137 417 149 976 0.0158 860 0.014 12.456 1.488
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 18 548 13 553 18 0.000496 13 0.000359 5.661 1.455
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 261 305 248 318 388 0.00691 377 0.00673 1.788 1.441
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 312 254 299 267 486 0.00787 498 0.00808 -1.810 1.439
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 295 271 282 284 477 0.00773 445 0.00722 4.713 1.436
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 388 178 376 190 705 0.0114 690 0.0112 1.695 1.416
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 212 354 200 366 317 0.00719 288 0.00654 6.316 1.393
*TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 2 564 0 566 2 5.83e-05 0 0 NA 1.387
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 12 554 8 558 12 0.000233 12 0.000234 -0.058 1.387
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 21 545 16 550 22 0.00057 16 0.000415 5.944 1.378
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 6 560 3 563 6 0.000156 3 7.79e-05 6.842 1.374
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 563 3 560 6 3293 0.048 3178 0.0464 6.024 1.374
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 167 399 157 409 223 0.00542 210 0.00511 3.396 1.284
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 450 116 441 125 1331 0.0173 1293 0.0168 2.868 1.270
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 46 520 40 526 56 0.00127 46 0.00104 5.462 1.246
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 504 62 497 69 2474 0.0401 2824 0.0458 -21.544 1.242
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 209 357 199 367 271 0.00571 266 0.00561 1.019 1.242
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 8 558 5 561 8 0.000194 5 0.000122 5.123 1.240
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 17 549 13 553 17 0.000441 13 0.000337 4.381 1.239
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 9 557 6 560 9 0.000248 6 0.000165 4.984 1.196
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 9 557 6 560 9 0.000219 6 0.000146 4.675 1.196
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 442 124 434 132 938 0.0152 941 0.0153 -0.449 1.173
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 21 545 17 549 22 0.000499 17 0.000386 4.482 1.169
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 21 545 17 549 21 0.000544 17 0.000441 3.826 1.169
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 3 563 1 565 3 6.8e-05 1 2.27e-05 7.340 1.164
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 10 556 7 559 10 0.000243 8 0.000195 2.677 1.161
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 342 224 333 233 593 0.0106 560 0.00999 4.532 1.158
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 503 63 497 69 1752 0.0284 1780 0.0289 -2.316 1.134
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 129 437 122 444 153 0.00297 139 0.00271 4.048 1.097
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 261 305 253 313 367 0.00476 372 0.00483 -0.818 1.085
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 101 465 95 471 117 0.00227 107 0.00208 3.287 1.058
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 15 551 12 554 17 0.000496 13 0.00038 4.651 1.053
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 554 12 551 15 2427 0.0315 2517 0.0327 -5.355 1.053
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 183 383 176 390 241 0.00586 214 0.00521 7.076 1.048
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 445 121 439 127 1093 0.0177 1060 0.0172 3.085 1.022
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 520 46 516 50 1627 0.0211 1642 0.0213 -1.219 0.982
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 343 223 337 229 584 0.00852 551 0.00805 4.129 0.966
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 120 446 115 451 139 0.0036 142 0.00369 -1.084 0.955
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 7 559 5 561 7 0.000159 5 0.000114 3.273 0.950
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 184 382 179 387 239 0.00387 247 0.00401 -1.690 0.918
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 228 338 223 343 308 0.00649 302 0.00637 1.155 0.906
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 342 224 337 229 541 0.00701 577 0.00749 -4.352 0.906
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 332 234 327 239 596 0.0135 536 0.0122 9.626 0.904
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 306 260 301 265 504 0.00817 520 0.00844 -2.332 0.902
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 43 523 40 526 46 0.00104 46 0.00104 -0.054 0.892
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 459 107 455 111 1071 0.0174 1140 0.0185 -6.670 0.890
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 129 437 125 441 156 0.00177 145 0.00165 2.358 0.879
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 512 54 509 57 1686 0.0273 1846 0.0299 -12.140 0.866
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 60 506 57 509 61 0.00138 62 0.00141 -0.532 0.861
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 354 212 350 216 601 0.0146 551 0.0134 8.170 0.851
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 242 324 238 328 344 0.00557 371 0.00602 -4.534 0.848
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 29 537 27 539 32 0.000726 29 0.000659 2.032 0.808
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 538 28 536 30 2105 0.0205 2159 0.021 -3.036 0.806
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 30 536 28 538 32 0.000881 30 0.000827 1.452 0.806
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 37 529 35 531 40 0.000842 39 0.000823 0.524 0.795
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 256 310 253 313 381 0.00679 401 0.00716 -3.420 0.793
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 520 46 518 48 1587 0.0257 1567 0.0254 1.441 0.783
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 499 67 497 69 1562 0.0253 1458 0.0237 8.541 0.769
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 135 431 133 433 159 0.00438 163 0.0045 -1.375 0.750
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 410 156 408 158 1018 0.0115 1105 0.0125 -7.090 0.748
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 2 564 1 565 2 6.48e-05 1 3.24e-05 4.351 0.693
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 5 561 4 562 6 0.000175 4 0.000117 4.170 0.693
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 11 555 10 556 11 0.000321 10 0.000292 1.285 0.693
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 58 508 57 509 65 0.00147 62 0.00141 1.369 0.693
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 566 0 565 1 5616 0.0546 5312 0.0517 10.233 0.693
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 16 550 15 551 17 0.000386 15 0.000341 1.877 0.693
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 17 549 16 550 17 0.000386 18 0.000409 -0.935 0.693
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 566 0 565 1 5247 0.0765 4954 0.0723 12.657 0.693
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 17 549 16 550 18 0.000408 17 0.000386 0.854 0.693
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 435 131 434 132 854 0.0111 912 0.0118 -5.584 0.693
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 21 545 20 546 21 0.000578 20 0.000552 0.869 0.693
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 566 0 565 1 7393 0.0958 7655 0.0994 -9.275 0.693
*E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 1 565 0 566 1 2.59e-05 0 0 NA 0.693
*REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 1 565 0 566 1 3.4e-05 0 0 NA 0.693
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 7 559 6 560 7 0.00017 6 0.000146 1.515 0.693
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 6 560 5 561 6 0.000175 5 0.000146 1.831 0.693
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 148 418 148 418 179 0.0029 170 0.00276 2.116 0.641
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 460 106 460 106 1061 0.0189 1096 0.0196 -3.694 0.634
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 62 504 62 504 67 0.00206 65 0.002 1.020 0.620
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 47 519 47 519 50 0.00105 48 0.00101 0.987 0.611
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 46 520 46 520 51 0.000992 54 0.00105 -1.468 0.610
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 522 44 522 44 1694 0.0274 1729 0.0281 -2.883 0.609
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 232 334 233 333 344 0.00669 348 0.00678 -0.841 0.601
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 479 87 480 86 1131 0.0147 1189 0.0154 -4.930 0.570
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 17 549 17 549 17 0.000386 18 0.000409 -0.935 0.564
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 273 293 275 291 437 0.00708 431 0.00699 0.819 0.561
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 65 501 66 500 70 0.00136 66 0.00128 1.650 0.556
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 387 179 389 177 666 0.0119 705 0.0126 -5.025 0.551
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 505 61 506 60 2456 0.0279 2895 0.0329 -22.136 0.551
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 59 507 60 506 64 0.00124 71 0.00138 -2.935 0.550
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 320 246 323 243 506 0.00902 535 0.00955 -4.287 0.519
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 36 530 37 529 38 0.000862 44 0.000999 -3.438 0.518
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 211 355 214 352 282 0.00594 293 0.00618 -2.415 0.516
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 8 558 8 558 8 0.000207 8 0.000208 -0.060 0.513
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 152 414 155 411 199 0.00322 213 0.00346 -3.110 0.502
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 493 73 495 71 1857 0.0211 2062 0.0234 -12.248 0.502
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 436 130 439 127 1000 0.0146 954 0.0139 4.364 0.492
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 541 25 542 24 4011 0.0715 3654 0.0652 19.961 0.487
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 353 213 357 209 755 0.00979 810 0.0105 -5.607 0.477
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 394 172 398 168 1244 0.0181 1515 0.0221 -21.273 0.467
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 4 562 4 562 4 0.000104 4 0.000104 -0.073 0.451
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 284 282 289 277 577 0.0112 589 0.0115 -1.842 0.447
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 452 114 456 110 1798 0.0204 2073 0.0235 -16.331 0.438
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 105 461 109 457 126 0.00204 136 0.00221 -2.777 0.434
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 55 511 58 508 64 0.00176 69 0.0019 -2.544 0.425
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 3 563 3 563 3 9.72e-05 3 9.73e-05 -0.075 0.421
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 563 3 563 3 6779 0.0659 6050 0.0589 23.379 0.421
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 473 93 477 89 1979 0.0257 2408 0.0313 -25.301 0.420
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 277 289 283 283 451 0.0102 476 0.0108 -4.426 0.413
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 11 555 12 554 11 0.00025 14 0.000318 -3.053 0.411
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 216 350 222 344 316 0.00768 307 0.00747 1.896 0.407
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 204 362 210 356 269 0.00436 285 0.00462 -3.084 0.405
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 444 122 449 117 1341 0.0174 1519 0.0197 -13.194 0.402
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 21 545 23 543 22 0.000606 23 0.000634 -0.912 0.389
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 410 156 416 150 857 0.0111 873 0.0113 -1.660 0.385
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 467 99 472 94 1483 0.0168 1711 0.0194 -14.872 0.382
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 273 293 280 286 396 0.00513 426 0.00553 -4.208 0.381
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 19 547 21 545 19 0.000431 23 0.000522 -3.172 0.378
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 329 237 336 230 630 0.0112 668 0.0119 -5.025 0.378
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 18 548 20 546 18 0.000467 20 0.000519 -1.840 0.372
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 479 87 484 82 1113 0.018 1204 0.0195 -8.525 0.369
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 398 168 405 161 697 0.0124 747 0.0133 -6.234 0.357
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 155 411 162 404 184 0.00328 204 0.00364 -4.725 0.354
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 28 538 31 535 28 0.000771 31 0.000855 -2.274 0.352
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 287 279 295 271 547 0.00709 577 0.00749 -3.643 0.351
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 304 262 312 254 517 0.00838 555 0.009 -5.229 0.350
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 477 89 483 83 1307 0.0233 1302 0.0232 0.296 0.330
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 55 511 60 506 62 0.00171 61 0.00168 0.469 0.325
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 449 117 456 110 1799 0.0233 2116 0.0275 -19.935 0.323
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 110 456 117 449 142 0.00253 157 0.0028 -4.042 0.323
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 528 38 532 34 2491 0.0444 2353 0.042 9.407 0.317
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 414 152 422 144 904 0.0146 871 0.0141 3.426 0.317
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 215 351 224 342 305 0.00593 315 0.00613 -2.048 0.316
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 383 183 392 174 689 0.0112 743 0.0121 -6.422 0.303
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 297 269 307 259 532 0.00862 544 0.00883 -1.741 0.296
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 60 506 66 500 68 0.00231 74 0.00252 -3.264 0.293
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 28 538 32 534 29 0.000799 33 0.00091 -2.924 0.293
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 9 557 11 555 9 0.000248 11 0.000303 -2.540 0.287
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 1 565 1 565 1 2.59e-05 1 2.6e-05 -0.130 0.287
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 55 511 61 505 62 0.00121 73 0.00142 -4.517 0.283
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 192 374 202 364 308 0.00399 291 0.00378 2.746 0.283
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 133 433 142 424 174 0.00282 185 0.003 -2.630 0.280
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 424 142 433 133 950 0.0123 936 0.0121 1.177 0.280
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 486 80 493 73 1553 0.0201 1602 0.0208 -3.657 0.279
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 340 226 351 215 898 0.016 1163 0.0208 -26.186 0.264
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 22 544 26 540 23 0.000559 55 0.00134 -16.768 0.262
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 139 427 149 417 178 0.00231 184 0.00239 -1.317 0.257
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 13 553 16 550 14 0.000386 16 0.000441 -2.113 0.256
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 7 559 9 557 7 0.000181 10 0.00026 -3.849 0.256
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 530 36 535 31 2872 0.0326 3139 0.0356 -13.039 0.255
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 269 297 281 285 437 0.00637 466 0.0068 -4.137 0.248
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 263 303 275 291 422 0.00684 450 0.0073 -4.285 0.248
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 308 258 320 246 614 0.00796 657 0.00853 -4.868 0.246
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 396 170 407 159 1088 0.0141 1299 0.0169 -16.833 0.243
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 226 340 238 328 294 0.00524 320 0.00571 -4.920 0.243
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 332 234 344 222 551 0.00982 599 0.0107 -6.652 0.243
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 506 60 513 53 1569 0.028 1643 0.0293 -6.331 0.241
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 51 515 58 508 55 0.00116 66 0.00139 -4.939 0.236
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 109 457 119 447 135 0.00241 141 0.00252 -1.743 0.233
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 140 426 151 415 170 0.00358 174 0.00367 -1.170 0.232
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 315 251 328 238 677 0.0132 941 0.0183 -30.220 0.224
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 16 550 20 546 18 0.00035 20 0.000389 -1.602 0.222
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 223 343 236 330 360 0.00467 384 0.00498 -3.555 0.221
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 212 354 225 341 324 0.00787 325 0.00791 -0.318 0.219
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 501 65 509 57 2001 0.0357 1870 0.0334 10.011 0.216
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 93 473 103 463 123 0.00239 125 0.00243 -0.686 0.215
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 362 204 375 191 564 0.00914 631 0.0102 -8.587 0.212
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 142 424 154 412 171 0.00277 181 0.00294 -2.422 0.210
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 2 564 3 563 2 5.83e-05 3 8.76e-05 -2.526 0.207
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 256 310 270 296 390 0.00632 443 0.00719 -8.085 0.205
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 314 252 328 238 531 0.00946 588 0.0105 -7.948 0.203
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 176 390 190 376 256 0.00622 254 0.00618 0.395 0.187
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 25 541 31 535 25 0.000689 31 0.000855 -4.495 0.185
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 467 99 478 88 1700 0.022 2050 0.0266 -22.326 0.184
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 124 442 137 429 159 0.00283 169 0.00302 -2.624 0.176
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 23 543 29 537 26 0.00059 29 0.000659 -2.136 0.175
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 118 448 131 435 157 0.00254 168 0.00273 -2.754 0.171
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 290 276 306 260 606 0.00687 728 0.00827 -12.109 0.169
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 374 192 389 177 1302 0.0127 1589 0.0155 -17.901 0.169
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 305 261 321 245 564 0.0101 669 0.0119 -13.659 0.168
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 245 321 261 305 381 0.00617 413 0.0067 -5.088 0.168
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 346 220 362 204 580 0.0103 646 0.0115 -8.778 0.160
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 451 115 464 102 1446 0.0328 1500 0.0341 -5.508 0.157
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 44 522 53 513 45 0.00124 57 0.00157 -6.613 0.156
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 3 563 5 561 3 7.78e-05 5 0.00013 -3.644 0.155
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 13 553 18 548 13 0.000358 20 0.000552 -6.503 0.148
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 492 74 503 63 1443 0.0187 1694 0.022 -17.594 0.147
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 50 516 60 506 53 0.00103 63 0.00123 -4.420 0.145
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 40 526 49 517 41 0.00093 53 0.0012 -6.222 0.145
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 106 460 120 446 124 0.00221 139 0.00248 -4.288 0.142
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 528 38 536 30 1801 0.0233 1872 0.0243 -4.868 0.139
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 291 275 309 257 417 0.0054 478 0.0062 -8.003 0.138
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 118 448 133 433 134 0.00217 159 0.00258 -6.340 0.135
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 117 449 132 434 133 0.00323 149 0.00363 -5.157 0.134
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 1 565 2 564 1 2.43e-05 2 4.87e-05 -2.835 0.133
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 356 210 374 192 862 0.0126 1095 0.016 -21.421 0.127
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 363 203 381 185 872 0.0141 1012 0.0164 -14.166 0.124
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 252 314 271 295 381 0.00494 450 0.00584 -9.311 0.124
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 506 60 517 49 2090 0.0271 2673 0.0347 -32.646 0.120
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 142 424 159 407 197 0.00383 212 0.00413 -3.652 0.120
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 31 535 40 526 34 0.000826 40 0.000973 -3.727 0.117
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 2 564 4 562 2 5.51e-05 4 0.00011 -4.192 0.115
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 2 564 4 562 2 5.51e-05 4 0.00011 -4.192 0.115
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 2 564 4 562 2 5.18e-05 4 0.000104 -4.071 0.115
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 156 410 174 392 240 0.00467 270 0.00526 -6.423 0.113
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 289 277 309 257 534 0.00952 647 0.0115 -14.931 0.112
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 460 106 475 91 1944 0.0252 2330 0.0302 -23.144 0.111
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 235 331 255 311 410 0.00797 482 0.00938 -11.517 0.110
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 222 344 242 324 292 0.00615 373 0.00787 -15.273 0.108
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 74 492 88 478 88 0.00171 108 0.0021 -6.732 0.107
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 529 37 538 28 3364 0.0382 4055 0.0461 -29.612 0.106
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 49 517 61 505 53 0.00112 65 0.00137 -5.423 0.101
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 472 94 487 79 1452 0.0235 1591 0.0258 -11.335 0.098
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 231 335 252 314 390 0.00632 406 0.00659 -2.612 0.098
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 458 108 474 92 1569 0.0203 1788 0.0232 -14.980 0.097
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 474 92 489 77 1057 0.0171 1166 0.0189 -10.337 0.095
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 330 236 351 215 685 0.0166 828 0.0202 -19.588 0.095
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 3 563 6 560 3 8.26e-05 6 0.000165 -5.110 0.093
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 87 479 103 463 97 0.00157 127 0.00206 -8.484 0.092
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 353 213 374 192 889 0.0115 1098 0.0143 -18.090 0.090
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 84 482 100 466 119 0.00251 130 0.00274 -3.549 0.089
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 470 96 486 80 1997 0.0259 2212 0.0287 -13.298 0.085
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 408 158 428 138 1190 0.0154 1501 0.0195 -23.068 0.081
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 274 292 297 269 382 0.00619 455 0.00738 -10.954 0.080
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 497 69 511 55 1704 0.0193 2006 0.0228 -18.201 0.080
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 116 450 135 431 143 0.00232 181 0.00294 -9.009 0.079
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 450 116 468 98 1270 0.0165 1470 0.0191 -15.040 0.077
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 402 164 423 143 1351 0.0175 1531 0.0199 -13.290 0.073
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 382 184 404 162 648 0.0105 709 0.0115 -7.403 0.071
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 293 273 317 249 600 0.00778 693 0.00899 -10.139 0.070
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 135 431 156 410 177 0.00373 241 0.00508 -14.977 0.070
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 226 340 250 316 336 0.00817 363 0.00883 -5.617 0.068
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 1 565 3 563 1 2.27e-05 3 6.81e-05 -4.404 0.064
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 314 252 339 227 642 0.0104 828 0.0134 -20.696 0.061
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 5 561 10 556 6 0.000165 10 0.000276 -5.269 0.060
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 5 561 10 556 5 0.000122 10 0.000243 -6.178 0.060
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 132 434 154 412 177 0.00344 195 0.0038 -4.547 0.060
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 461 105 480 86 1283 0.0208 1295 0.021 -1.226 0.058
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 16 550 25 541 16 0.000441 25 0.00069 -7.471 0.057
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 16 550 25 541 16 0.000415 29 0.000753 -9.706 0.057
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 350 216 376 190 595 0.00964 646 0.0105 -6.491 0.048
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 403 163 427 139 802 0.0104 826 0.0107 -2.490 0.048
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 309 257 336 230 702 0.0125 892 0.0159 -21.396 0.047
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 466 100 486 80 1280 0.0145 1296 0.0147 -1.319 0.045
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 278 288 306 260 489 0.00871 532 0.00949 -6.319 0.043
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 99 467 121 445 144 0.0028 161 0.00313 -4.716 0.043
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 191 375 218 348 238 0.00386 292 0.00474 -10.093 0.042
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 417 149 441 125 1065 0.0138 1129 0.0147 -5.559 0.042
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 314 252 342 224 729 0.0118 906 0.0147 -18.857 0.041
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 136 430 161 405 168 0.00299 193 0.00344 -6.048 0.040
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 462 104 483 83 1450 0.0188 1679 0.0218 -16.135 0.040
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 12 554 21 545 12 0.000311 23 0.000597 -9.223 0.039
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 51 515 69 497 58 0.0015 79 0.00205 -9.516 0.034
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 245 321 275 291 488 0.00712 579 0.00845 -11.491 0.033
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 236 330 266 300 503 0.00896 671 0.012 -21.749 0.032
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 100 466 124 442 113 0.00348 139 0.00428 -9.706 0.031
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 19 547 31 535 20 0.000583 32 0.000934 -9.052 0.030
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 335 231 365 201 614 0.00995 654 0.0106 -5.086 0.029
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 151 415 179 387 217 0.00387 250 0.00446 -7.014 0.029
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 59 507 79 487 75 0.00158 104 0.00219 -10.321 0.028
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 344 222 374 192 946 0.0153 1266 0.0205 -28.876 0.028
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 173 393 203 363 275 0.00401 334 0.00488 -9.786 0.026
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 250 316 282 284 352 0.0057 411 0.00667 -9.323 0.025
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 466 100 489 77 1163 0.0207 1245 0.0222 -7.955 0.025
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 133 433 161 405 199 0.00387 242 0.00471 -9.674 0.025
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 231 335 264 302 375 0.00911 666 0.0162 -44.142 0.021
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 369 197 400 166 770 0.0137 897 0.016 -14.309 0.021
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 348 218 380 186 719 0.0116 997 0.0162 -28.192 0.020
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 423 143 451 115 1377 0.0178 1684 0.0219 -21.544 0.020
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 397 169 427 139 1251 0.0162 1604 0.0208 -25.336 0.019
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 274 292 308 258 422 0.00752 503 0.00898 -12.133 0.019
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 284 282 318 248 436 0.00706 474 0.00769 -5.638 0.019
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 364 202 396 170 751 0.0122 892 0.0145 -15.163 0.019
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 89 477 115 451 99 0.00273 150 0.00414 -17.272 0.018
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 34 532 52 514 42 0.000817 60 0.00117 -8.104 0.016
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 54 512 76 490 58 0.00113 85 0.00165 -10.205 0.016
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 33 533 51 515 36 0.000817 53 0.0012 -8.792 0.015
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 132 434 163 403 152 0.00246 208 0.00337 -12.364 0.015
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 445 121 473 93 1511 0.0245 1971 0.032 -33.477 0.014
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 91 475 119 447 117 0.0019 172 0.00279 -13.340 0.013
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 90 476 118 448 120 0.00214 141 0.00252 -5.935 0.013
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 195 371 231 335 260 0.00632 321 0.00781 -13.331 0.012
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 181 385 217 349 218 0.00671 319 0.00983 -24.867 0.011
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 42 524 64 502 53 0.000859 79 0.00128 -9.306 0.009
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 538 28 552 14 2206 0.0322 2216 0.0324 -0.846 0.009
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 355 211 392 174 676 0.012 842 0.015 -19.242 0.009
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 116 450 149 417 132 0.00235 178 0.00318 -11.517 0.008
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 207 359 246 320 371 0.00661 498 0.00889 -19.054 0.008
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 172 394 210 356 261 0.00423 341 0.00553 -13.817 0.007
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 335 231 374 192 878 0.0128 1148 0.0168 -24.237 0.007
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 361 205 399 167 582 0.00943 693 0.0112 -13.520 0.007
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 341 225 380 186 832 0.0135 1154 0.0187 -30.391 0.007
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 316 250 356 210 711 0.0104 917 0.0134 -20.662 0.007
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 78 488 108 458 88 0.00157 120 0.00214 -9.755 0.006
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 260 306 301 265 509 0.0099 841 0.0164 -40.102 0.006
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 144 422 181 385 224 0.00399 353 0.0063 -22.921 0.006
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 399 167 435 131 1343 0.0174 1801 0.0234 -31.036 0.006
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 80 486 111 455 104 0.00219 143 0.00302 -11.839 0.005
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 135 431 173 393 198 0.00353 321 0.00573 -22.909 0.005
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 62 504 91 475 75 0.00122 117 0.0019 -12.343 0.004
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 144 422 183 383 167 0.00352 226 0.00477 -14.258 0.004
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 196 370 238 328 249 0.00484 321 0.00625 -14.048 0.004
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 59 507 88 478 76 0.00135 126 0.00225 -14.844 0.004
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 3 563 12 554 3 8.26e-05 12 0.000331 -10.761 0.004
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 5 561 16 550 5 0.000138 16 0.000441 -11.386 0.003
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 318 248 362 204 776 0.0101 1070 0.0139 -25.714 0.003
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 52 514 81 485 62 0.00151 100 0.00243 -14.791 0.003
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 203 363 248 318 307 0.00746 472 0.0115 -29.686 0.003
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 321 245 366 200 680 0.011 1101 0.0179 -40.607 0.003
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 364 202 407 159 1075 0.0174 1515 0.0246 -36.344 0.002
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 27 539 50 516 32 0.000674 56 0.00118 -11.618 0.002
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 410 156 450 116 1412 0.0183 1844 0.0239 -28.953 0.002
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 413 153 453 113 1021 0.0149 1247 0.0182 -19.514 0.002
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 69 497 103 463 79 0.0023 121 0.00353 -16.291 0.002
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 108 458 148 418 154 0.0025 194 0.00315 -9.161 0.002
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 90 476 128 438 116 0.00244 172 0.00363 -15.488 0.002
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 281 285 330 236 551 0.00893 849 0.0138 -32.676 0.001
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 191 375 239 327 274 0.00444 379 0.00615 -17.189 0.001
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 139 427 184 382 195 0.00348 241 0.0043 -9.922 0.001
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 105 461 147 419 130 0.00232 202 0.0036 -16.895 0.001
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 7 559 22 544 8 0.00022 22 0.000607 -12.354 0.001
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 272 294 323 243 432 0.0077 498 0.00889 -9.954 0.001
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 341 225 390 176 742 0.012 938 0.0152 -20.517 0.001
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 2 564 12 554 2 5.51e-05 12 0.000331 -11.951 0.001
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 27 539 53 513 28 0.000544 59 0.00115 -14.034 0.001
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 276 290 328 238 570 0.00739 804 0.0104 -23.564 0.001
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 257 309 310 256 477 0.00773 693 0.0112 -26.196 0.001
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 355 211 405 161 1052 0.0136 1418 0.0184 -27.879 0.001
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 339 227 392 174 838 0.0109 965 0.0125 -11.754 0.000
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 37 529 69 497 42 0.000953 97 0.0022 -20.967 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 139 427 191 375 164 0.00319 256 0.00498 -20.039 0.000
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 114 452 164 402 170 0.00386 255 0.00579 -20.051 0.000
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 249 317 308 258 409 0.00729 664 0.0118 -33.118 0.000
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 332 234 389 177 793 0.0103 1109 0.0144 -27.150 0.000
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 186 380 244 322 245 0.00397 342 0.00555 -16.710 0.000
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 267 299 327 239 386 0.00813 492 0.0104 -17.424 0.000
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 349 217 406 160 632 0.00819 751 0.00975 -12.446 0.000
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 106 460 158 408 145 0.00258 228 0.00407 -18.334 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 12 554 36 530 12 0.000292 37 0.0009 -15.967 0.000
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 102 464 154 412 112 0.00272 185 0.0045 -20.901 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 108 458 161 405 133 0.00259 259 0.00504 -27.256 0.000
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 10 556 33 533 10 0.000259 34 0.000883 -16.513 0.000
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 321 245 383 183 713 0.0116 802 0.013 -10.125 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 119 447 175 391 159 0.00309 294 0.00572 -27.423 0.000
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 366 200 425 141 979 0.0159 1316 0.0214 -29.837 0.000
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 103 463 157 409 141 0.00228 240 0.00389 -20.311 0.000
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 34 532 71 495 39 0.000885 84 0.00191 -18.437 0.000
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 39 527 80 486 45 0.00102 100 0.00227 -20.653 0.000
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 116 450 180 386 129 0.00209 224 0.00363 -20.170 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 78 488 139 427 89 0.00173 191 0.00372 -25.673 0.000
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 126 440 197 369 146 0.00237 250 0.00406 -20.906 0.000
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 79 487 142 424 83 0.00134 174 0.00282 -21.900 0.000
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 30 536 76 490 36 0.000817 93 0.00211 -22.187 0.000
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 565 1 566 0 4434 0.0647 4488 0.0655 -2.785 0.000
BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 0 566 0 566 0 0 0 0 NA 0.000
SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 0 566 2 564 0 0 2 5.19e-05 -5.749 0.000

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HOMER results

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