TF JASPAR ID Class Family Tax Group IC GC Content Target region hits Target region non-hits Background region hits Background region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 576 50 469 157 1493 0.022 1131 0.017 34.210 36.877 ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 540 86 426 200 1253 0.020 875 0.014 42.573 32.532 SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 132 494 42 584 147 0.003 44 0.001 58.058 30.473 ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 475 151 356 270 856 0.013 618 0.009 30.323 28.059 ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 541 85 439 187 1162 0.017 857 0.013 33.053 27.295 FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 509 117 399 227 973 0.014 702 0.010 32.417 26.998 FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 510 116 405 221 989 0.015 739 0.011 29.145 25.067 ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 560 66 471 155 1391 0.020 979 0.014 41.830 24.591 TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 536 90 447 179 2121 0.037 1618 0.029 43.800 21.352 Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 431 195 327 299 723 0.012 545 0.009 25.313 20.566 Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 442 184 339 287 805 0.012 581 0.009 29.425 20.541 ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 501 125 408 218 998 0.015 724 0.011 32.278 19.863 ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 487 139 393 233 923 0.014 686 0.010 28.667 19.369 TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 540 86 459 167 2322 0.041 1784 0.031 44.679 18.750 ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 600 26 546 80 1949 0.031 1414 0.023 47.598 17.724 ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 455 171 368 258 1082 0.016 913 0.013 17.708 15.767 RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 270 356 185 441 355 0.005 227 0.003 26.845 14.786 INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 357 269 269 357 566 0.010 426 0.008 23.504 14.680 SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 224 402 145 481 279 0.006 173 0.004 30.140 14.289 ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 467 159 389 237 1093 0.034 754 0.023 57.102 13.505 NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 427 199 348 278 805 0.012 604 0.009 25.891 12.813 ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 358 268 278 348 525 0.008 392 0.006 21.231 12.459 KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 516 110 449 177 1869 0.030 1614 0.026 21.198 12.370 TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 333 293 255 371 604 0.012 461 0.009 24.033 11.969 MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 185 441 121 505 223 0.003 145 0.002 20.449 11.023 ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 290 336 217 409 389 0.006 284 0.004 19.678 11.007 TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 568 58 521 105 3795 0.067 2989 0.053 52.271 9.879 Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 583 43 541 85 2103 0.040 1652 0.032 40.500 9.750 TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 327 299 259 367 583 0.011 439 0.008 24.799 9.527 E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 505 121 451 175 2339 0.038 2008 0.032 24.757 8.488 ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 282 344 221 405 363 0.005 300 0.004 11.464 8.223 Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 569 57 529 97 1767 0.029 1403 0.023 32.472 7.888 ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 221 405 165 461 283 0.005 196 0.003 20.582 7.886 Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 518 108 469 157 1431 0.023 1200 0.019 22.216 7.734 TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 294 332 238 388 497 0.009 395 0.008 18.495 7.099 EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 123 503 81 545 140 0.003 92 0.002 18.688 7.096 Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 265 361 212 414 406 0.009 274 0.006 30.899 6.701 STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 437 189 386 240 843 0.014 662 0.011 23.365 6.541 NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 44 582 20 606 48 0.001 21 0.001 24.245 6.540 ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 554 72 516 110 1425 0.019 1350 0.018 6.072 6.525 Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 583 43 552 74 3501 0.051 3007 0.044 28.965 6.367 EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 578 48 546 80 3529 0.073 3038 0.063 34.216 6.295 SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 554 72 517 109 2551 0.041 2249 0.036 21.360 6.286 ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 345 281 294 332 521 0.009 445 0.008 12.452 6.057 Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 509 117 468 158 1189 0.017 981 0.014 21.050 5.767 EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 123 503 86 540 136 0.002 90 0.002 16.758 5.765 NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 269 357 221 405 367 0.008 290 0.006 17.494 5.734 SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 532 94 495 131 2464 0.054 2035 0.045 37.507 5.527 PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 227 399 182 444 287 0.006 228 0.005 15.104 5.524 SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 167 459 127 499 242 0.006 204 0.005 10.932 5.377 E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 601 25 579 47 3190 0.052 2695 0.044 32.162 5.264 HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 176 450 136 490 208 0.004 163 0.003 12.670 5.225 ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 316 310 271 355 449 0.010 369 0.008 16.115 5.061 NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 41 585 21 605 43 0.001 22 0.001 18.414 5.056 Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 426 200 383 243 800 0.016 680 0.014 17.239 5.035 Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 594 32 571 55 2463 0.040 1928 0.031 40.902 4.957 SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 483 143 445 181 1332 0.023 1178 0.021 15.589 4.775 SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 59 567 36 590 61 0.001 37 0.001 15.238 4.685 NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 440 186 400 226 1870 0.030 1646 0.027 18.426 4.660 ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 143 483 109 517 157 0.003 118 0.002 12.397 4.610 KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 614 12 599 27 6596 0.097 5443 0.080 51.282 4.529 Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 31 595 15 611 31 0.001 15 0.000 16.983 4.455 GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 122 504 91 535 144 0.003 109 0.002 12.504 4.428 SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 604 22 586 40 4970 0.080 4052 0.066 49.259 4.340 HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 425 201 387 239 743 0.016 626 0.014 18.137 4.253 ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 108 518 80 546 114 0.002 84 0.001 11.298 4.120 MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 12 614 3 623 12 0.000 3 0.000 23.732 4.072 Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 514 112 483 143 1111 0.013 1051 0.012 5.177 4.042 MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 174 452 141 485 214 0.003 171 0.003 10.358 3.989 USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 444 182 409 217 804 0.013 736 0.012 8.273 3.934 ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 232 394 197 429 307 0.005 249 0.004 12.697 3.843 FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 577 49 555 71 1670 0.025 1556 0.023 9.124 3.830 MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 587 39 567 59 2299 0.034 1885 0.028 30.439 3.791 RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 35 591 20 606 36 0.001 22 0.001 12.261 3.638 RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 528 98 501 125 1316 0.021 1118 0.018 19.707 3.600 BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 137 489 109 517 171 0.003 128 0.002 11.979 3.600 SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 234 392 201 425 290 0.005 244 0.004 9.726 3.550 HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 314 312 280 346 467 0.007 428 0.006 5.911 3.478 ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 577 49 557 69 1761 0.026 1685 0.025 5.805 3.416 KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 258 368 226 400 449 0.009 398 0.008 9.527 3.325 Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 38 588 24 602 38 0.001 25 0.001 9.683 3.105 RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 389 237 359 267 608 0.009 548 0.008 8.061 3.051 RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 459 167 432 194 789 0.010 734 0.010 6.038 2.950 EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 144 482 120 506 192 0.004 163 0.004 8.755 2.892 TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 517 109 494 132 1167 0.017 1148 0.017 1.686 2.859 SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 626 0 622 4 3651 0.048 3580 0.047 3.479 2.777 MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 142 484 119 507 166 0.004 140 0.004 9.281 2.767 SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 619 7 611 15 4106 0.042 3331 0.034 35.994 2.730 TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 284 342 257 369 377 0.006 329 0.005 8.325 2.674 Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 554 72 536 90 1362 0.022 1307 0.021 4.985 2.576 Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 290 336 264 362 446 0.010 387 0.009 11.585 2.558 Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 45 581 32 594 46 0.001 32 0.001 9.542 2.540 ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 246 380 221 405 380 0.008 318 0.007 13.438 2.521 ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 77 549 61 565 83 0.002 63 0.001 9.044 2.432 EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 242 384 218 408 419 0.007 405 0.007 2.246 2.422 TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 582 44 568 58 3787 0.061 3293 0.053 29.153 2.413 JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 257 369 234 392 359 0.007 322 0.007 7.670 2.289 Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 266 360 244 382 383 0.004 356 0.004 3.997 2.176 ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 73 553 59 567 86 0.002 68 0.001 8.412 2.156 GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 312 314 290 336 473 0.008 442 0.007 4.836 2.142 STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 172 454 153 473 219 0.005 178 0.004 11.864 2.096 NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 626 0 623 3 5206 0.069 5128 0.068 3.182 2.082 Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 211 415 191 435 283 0.006 247 0.005 8.829 2.079 Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 499 127 482 144 1157 0.017 1035 0.015 11.982 1.994 TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 530 96 515 111 1844 0.030 1684 0.027 12.978 1.942 SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 66 560 54 572 69 0.001 56 0.001 6.221 1.928 Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 247 379 228 398 338 0.006 309 0.006 5.899 1.916 BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 303 323 284 342 465 0.007 419 0.006 7.059 1.871 NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 47 579 37 589 48 0.001 40 0.001 4.518 1.867 RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 39 587 30 596 41 0.001 33 0.001 5.168 1.827 Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 323 303 305 321 470 0.008 440 0.007 4.689 1.782 MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 42 584 33 593 42 0.001 34 0.001 5.271 1.770 Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 188 438 172 454 226 0.005 203 0.004 5.993 1.746 ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 157 469 142 484 212 0.004 176 0.004 10.113 1.733 IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 18 608 12 614 18 0.000 12 0.000 6.429 1.727 NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 220 406 204 422 273 0.004 267 0.004 1.107 1.686 TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 411 215 395 231 696 0.010 669 0.010 3.236 1.671 TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 586 40 577 49 1901 0.022 1971 0.023 -4.628 1.663 ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 38 588 30 596 40 0.001 34 0.001 3.807 1.653 GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 83 543 72 554 89 0.002 80 0.001 3.443 1.632 Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 29 597 22 604 30 0.001 23 0.001 5.794 1.632 Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 473 153 459 167 970 0.014 928 0.014 4.296 1.610 IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 22 604 16 610 22 0.001 16 0.000 6.318 1.584 Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 151 475 138 488 190 0.002 159 0.002 6.462 1.558 HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 80 546 70 556 91 0.002 79 0.002 4.825 1.529 MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 615 11 610 16 2862 0.034 2784 0.033 4.111 1.521 Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 585 41 577 49 2113 0.031 2206 0.032 -6.501 1.505 SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 237 389 223 403 323 0.006 287 0.005 7.617 1.501 JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 177 449 164 462 215 0.003 195 0.003 4.251 1.500 TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 565 61 556 70 2317 0.037 2162 0.035 11.106 1.469 NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 536 90 526 100 1426 0.021 1405 0.021 1.678 1.430 ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 262 364 249 377 333 0.005 315 0.005 3.154 1.406 USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 451 175 439 187 811 0.013 832 0.013 -2.521 1.401 Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 289 337 276 350 401 0.005 423 0.005 -3.092 1.395 REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 445 181 433 193 783 0.011 675 0.010 13.125 1.392 FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 323 303 310 316 519 0.008 516 0.008 0.365 1.391 MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 32 594 26 600 34 0.001 27 0.000 4.622 1.383 PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 87 539 78 548 102 0.002 89 0.002 5.113 1.378 Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 564 62 556 70 1768 0.029 1595 0.026 14.426 1.348 HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 57 569 50 576 64 0.001 53 0.001 5.406 1.301 RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 66 560 59 567 71 0.002 63 0.002 4.464 1.252 RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 8 618 5 621 8 0.000 5 0.000 5.467 1.240 Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 203 423 193 433 278 0.006 266 0.006 2.792 1.230 EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 103 523 95 531 122 0.003 120 0.003 0.680 1.225 NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 580 46 574 52 2250 0.033 2394 0.035 -9.615 1.206 Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 516 110 508 118 1337 0.022 1218 0.020 11.308 1.190 E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 3 623 1 625 3 0.000 1 0.000 8.360 1.164 BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 3 623 1 625 3 0.000 1 0.000 7.343 1.164 GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 412 214 403 223 760 0.011 733 0.011 3.087 1.147 Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 303 323 294 332 458 0.007 437 0.006 3.119 1.123 EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 12 614 9 617 12 0.000 13 0.000 -1.223 1.107 NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 122 504 115 511 132 0.002 130 0.002 0.535 1.101 Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 28 598 24 602 29 0.001 27 0.001 1.397 1.092 MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 624 2 622 4 6675 0.059 5910 0.052 24.849 1.069 HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 272 354 264 362 400 0.006 423 0.006 -3.612 1.065 TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 161 465 154 472 204 0.004 186 0.003 4.525 1.056 Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 39 587 35 591 40 0.001 36 0.001 2.540 1.022 FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 387 239 380 246 676 0.011 710 0.011 -4.340 1.011 RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 19 607 16 610 20 0.000 16 0.000 3.694 1.005 ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 85 541 80 546 103 0.002 91 0.002 4.828 0.997 Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 22 604 19 607 22 0.001 20 0.000 1.800 0.979 MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 6 620 4 622 6 0.000 4 0.000 3.667 0.977 MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 515 111 510 116 1190 0.014 1148 0.013 3.437 0.955 TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 600 26 597 29 2466 0.036 2243 0.033 14.995 0.938 TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 8 618 6 620 8 0.000 6 0.000 3.405 0.930 EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 545 81 541 85 1536 0.023 1668 0.025 -10.464 0.913 TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 40 586 37 589 43 0.001 43 0.001 -0.042 0.899 HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 587 39 584 42 2820 0.033 3584 0.042 -37.022 0.894 FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 584 42 581 45 3113 0.032 3971 0.041 -36.921 0.886 JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 50 576 47 579 53 0.001 52 0.001 0.438 0.876 HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 137 489 133 493 156 0.003 155 0.003 0.218 0.871 Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 490 136 486 140 1032 0.014 1041 0.014 -0.935 0.870 FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 407 219 403 223 723 0.012 719 0.012 0.412 0.845 Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 293 333 289 337 413 0.005 443 0.005 -4.102 0.838 MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 112 514 109 517 128 0.002 125 0.002 0.844 0.819 Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 134 492 131 495 171 0.003 162 0.003 2.500 0.810 NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 589 37 587 39 1951 0.029 1996 0.029 -3.363 0.792 MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 406 220 403 223 689 0.010 684 0.010 0.527 0.792 Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 272 354 269 357 361 0.006 350 0.006 1.891 0.788 NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 339 287 336 290 503 0.010 516 0.010 -2.152 0.788 NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 53 573 51 575 62 0.002 60 0.002 1.051 0.778 MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 574 52 572 54 1673 0.020 1821 0.021 -10.025 0.777 CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 63 563 61 565 68 0.002 65 0.002 1.577 0.771 NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 542 84 540 86 1366 0.016 1312 0.015 4.151 0.761 TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 356 270 354 272 587 0.012 602 0.012 -2.389 0.740 MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 312 314 310 316 489 0.011 500 0.011 -1.999 0.739 T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 8 618 7 619 8 0.000 7 0.000 1.455 0.693 TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 459 167 458 168 851 0.010 920 0.011 -6.549 0.693 PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 30 596 29 597 32 0.001 34 0.001 -1.231 0.693 GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 97 529 96 530 107 0.003 105 0.003 0.778 0.693 SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 61 565 60 566 65 0.001 66 0.001 -0.432 0.693 ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 625 1 624 2 5945 0.052 5604 0.049 11.268 0.693 Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 25 601 24 602 26 0.001 27 0.001 -0.763 0.693 BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 1 625 0 626 1 0.000 0 0.000 NA 0.693 PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 1 625 0 626 1 0.000 0 0.000 NA 0.693 E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 1 625 0 626 1 0.000 0 0.000 NA 0.693 Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 344 282 344 282 523 0.007 561 0.007 -4.900 0.649 JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 347 279 347 279 558 0.009 598 0.010 -5.528 0.649 Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 309 317 310 316 489 0.004 539 0.005 -5.345 0.607 BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 371 255 372 254 704 0.011 682 0.011 2.725 0.605 Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 36 590 36 590 37 0.001 40 0.001 -1.817 0.601 TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 590 36 590 36 1868 0.022 2129 0.025 -16.318 0.601 Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 431 195 432 194 846 0.011 918 0.012 -7.257 0.600 Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 529 97 530 96 1351 0.020 1439 0.021 -7.524 0.576 GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 75 551 76 550 82 0.001 85 0.001 -1.172 0.564 E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 16 610 16 610 16 0.000 16 0.000 -0.048 0.561 TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 187 439 189 437 218 0.003 239 0.004 -4.355 0.556 NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 146 480 148 478 177 0.003 190 0.004 -3.460 0.546 Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 11 615 11 615 11 0.000 13 0.000 -2.266 0.536 STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 582 44 583 43 2116 0.034 2086 0.034 2.074 0.531 FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 80 546 82 544 85 0.002 94 0.002 -3.521 0.511 Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 72 554 74 552 80 0.001 83 0.001 -1.185 0.504 NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 570 56 572 54 1988 0.029 1941 0.029 3.291 0.482 CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 106 520 109 517 117 0.003 123 0.003 -2.147 0.482 NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 22 604 23 603 22 0.000 26 0.001 -2.978 0.479 IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 5 621 5 621 5 0.000 5 0.000 -0.065 0.472 Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 579 47 581 45 1797 0.021 1857 0.022 -4.094 0.466 ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 19 607 20 606 19 0.000 21 0.000 -1.789 0.466 TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 607 19 608 18 2777 0.041 2490 0.037 18.375 0.461 LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 41 585 43 583 42 0.001 46 0.001 -2.327 0.458 TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 299 327 304 322 427 0.006 491 0.007 -9.233 0.458 PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 287 339 292 334 448 0.005 515 0.006 -8.438 0.457 TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 235 391 240 386 286 0.004 330 0.005 -7.735 0.452 ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 4 622 4 622 4 0.000 4 0.000 -0.068 0.451 Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 4 622 4 622 4 0.000 4 0.000 -0.071 0.451 IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 72 554 75 551 81 0.002 80 0.002 0.374 0.451 NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 551 75 554 72 1644 0.017 1687 0.017 -2.896 0.451 Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 16 610 17 609 16 0.000 18 0.000 -1.987 0.450 NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 511 115 515 111 1233 0.016 1228 0.016 0.332 0.441 FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 567 59 570 56 2374 0.024 2699 0.028 -16.907 0.427 Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 94 532 98 528 105 0.002 109 0.002 -1.317 0.427 Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 303 323 309 317 444 0.008 443 0.008 0.093 0.425 HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 270 356 276 350 495 0.009 548 0.010 -7.957 0.423 IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 89 537 93 533 99 0.003 105 0.003 -2.739 0.422 PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 52 574 55 571 56 0.001 60 0.001 -1.832 0.420 FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 383 243 389 237 659 0.011 614 0.010 5.971 0.419 FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 598 28 600 26 3588 0.037 4174 0.043 -24.678 0.413 Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 278 348 285 341 405 0.006 439 0.006 -5.213 0.393 NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 154 472 160 466 187 0.004 224 0.005 -9.655 0.392 Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 387 239 394 232 586 0.007 665 0.008 -8.767 0.386 Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 61 565 65 561 65 0.001 70 0.001 -2.114 0.385 Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 403 223 410 216 821 0.013 842 0.014 -2.507 0.382 CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 35 591 38 588 36 0.001 39 0.001 -1.840 0.378 EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 181 445 188 438 206 0.004 249 0.005 -9.904 0.371 BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 569 57 573 53 3095 0.045 3870 0.057 -40.731 0.369 RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 53 573 57 569 56 0.001 62 0.001 -2.895 0.369 Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 453 173 460 166 1017 0.015 1087 0.016 -6.864 0.365 Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 159 467 166 460 197 0.003 208 0.003 -2.586 0.361 RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 71 555 76 550 75 0.002 80 0.002 -2.283 0.356 JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 391 235 399 227 702 0.011 657 0.011 5.769 0.355 Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 15 611 17 609 16 0.000 18 0.000 -1.809 0.351 Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 27 599 30 596 28 0.001 32 0.001 -2.958 0.348 ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 144 482 152 474 171 0.003 181 0.003 -2.630 0.321 TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 281 345 291 335 425 0.009 482 0.011 -10.187 0.310 HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 625 1 625 1 5481 0.072 5271 0.070 8.789 0.287 FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 582 44 587 39 2229 0.023 2448 0.025 -11.978 0.285 ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 243 383 254 372 328 0.006 358 0.007 -5.802 0.280 MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 407 219 418 208 704 0.010 714 0.010 -1.271 0.271 E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 48 578 54 572 52 0.001 57 0.001 -2.337 0.268 PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 14 612 17 609 14 0.000 17 0.000 -3.044 0.266 RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 13 613 16 610 13 0.000 16 0.000 -2.950 0.257 E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 3 623 4 622 3 0.000 4 0.000 -1.944 0.256 GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 375 251 387 239 652 0.010 794 0.012 -16.108 0.256 FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 546 80 554 72 1916 0.020 2214 0.023 -17.059 0.246 TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 413 213 425 201 695 0.008 821 0.010 -12.572 0.245 Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 54 572 61 565 59 0.001 67 0.002 -4.076 0.245 Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 5 621 7 619 5 0.000 7 0.000 -3.079 0.214 Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 5 621 7 619 5 0.000 7 0.000 -3.171 0.214 CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 15 611 19 607 15 0.000 19 0.000 -3.478 0.214 FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 382 244 396 230 759 0.012 891 0.014 -14.861 0.212 Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 87 539 97 529 93 0.002 109 0.002 -5.786 0.211 ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 2 624 3 623 3 0.000 3 0.000 -0.086 0.207 GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 8 618 11 615 9 0.000 11 0.000 -2.307 0.196 MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 4 622 6 620 4 0.000 6 0.000 -3.222 0.187 Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 54 572 63 563 63 0.001 71 0.002 -3.723 0.181 FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 488 138 501 125 1289 0.013 1494 0.015 -14.232 0.181 Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 533 93 544 82 1518 0.018 1862 0.022 -22.903 0.179 Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 597 29 603 23 2235 0.030 2379 0.031 -9.132 0.175 Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 22 604 28 598 24 0.001 28 0.001 -3.066 0.170 TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 403 223 419 207 694 0.010 749 0.011 -6.471 0.169 TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 346 280 363 263 520 0.008 602 0.010 -11.213 0.165 OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 544 82 555 71 1760 0.021 2098 0.025 -21.246 0.163 PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 6 620 9 617 6 0.000 9 0.000 -4.173 0.162 XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 36 590 44 582 37 0.001 45 0.001 -4.505 0.162 MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 521 105 534 92 1676 0.020 2091 0.025 -26.100 0.149 Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 40 586 49 577 44 0.001 54 0.001 -5.488 0.146 Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 430 196 447 179 739 0.011 769 0.011 -3.523 0.143 Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 498 128 513 113 1769 0.021 2430 0.029 -38.593 0.134 SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 1 625 2 624 1 0.000 2 0.000 -2.921 0.133 NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 535 91 548 78 1449 0.023 1384 0.022 5.743 0.132 Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 21 605 28 598 21 0.001 28 0.001 -5.496 0.130 TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 168 458 186 440 200 0.003 238 0.004 -8.237 0.124 FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 440 186 458 168 1280 0.021 1734 0.028 -36.790 0.124 KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 10 616 15 611 11 0.000 17 0.000 -6.217 0.119 POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 4 622 7 619 4 0.000 7 0.000 -4.591 0.119 PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 19 607 26 600 20 0.000 29 0.001 -5.832 0.119 Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 112 514 128 498 132 0.003 153 0.004 -7.066 0.118 SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 2 624 4 622 2 0.000 4 0.000 -4.068 0.115 FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 402 224 422 204 997 0.018 1303 0.023 -29.813 0.111 Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 338 288 359 267 563 0.008 603 0.009 -5.248 0.111 Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 438 188 457 169 846 0.014 1027 0.017 -18.982 0.111 FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 363 263 384 242 694 0.008 809 0.010 -11.564 0.108 HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 52 574 64 562 57 0.001 70 0.001 -5.427 0.108 MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 423 203 443 183 900 0.011 1163 0.014 -22.046 0.105 OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 542 84 556 70 2072 0.024 2685 0.032 -34.123 0.104 GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 262 364 284 342 383 0.008 427 0.009 -8.075 0.100 TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 576 50 587 39 2032 0.030 2105 0.031 -5.244 0.098 ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 119 507 137 489 134 0.002 160 0.003 -6.872 0.096 Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 161 465 181 445 197 0.003 233 0.003 -7.521 0.096 FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 447 179 467 159 1160 0.014 1506 0.018 -25.536 0.095 Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 493 133 511 115 1572 0.018 2001 0.024 -27.556 0.093 Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 85 541 101 525 93 0.001 114 0.002 -6.267 0.092 Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 73 553 88 538 84 0.002 96 0.002 -4.950 0.092 BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 551 75 565 61 2435 0.029 3125 0.037 -35.702 0.090 Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 335 291 358 268 582 0.009 586 0.009 -0.629 0.090 ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 499 127 517 109 1407 0.017 1572 0.018 -11.981 0.089 RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 244 382 267 359 324 0.005 373 0.005 -8.104 0.087 Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 485 141 504 122 1353 0.016 1799 0.021 -30.160 0.086 TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 10 616 16 610 10 0.000 16 0.000 -5.243 0.086 SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 402 224 425 201 699 0.010 774 0.011 -8.655 0.079 GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 165 461 187 439 214 0.003 219 0.003 -1.006 0.077 Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 577 49 589 37 2032 0.018 2153 0.019 -6.553 0.076 Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 501 125 520 106 1274 0.015 1516 0.018 -17.834 0.075 GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 426 200 449 177 832 0.012 1236 0.018 -36.762 0.072 NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 170 456 193 433 209 0.003 252 0.004 -8.633 0.070 PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 56 570 71 555 59 0.001 77 0.001 -7.151 0.069 DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 144 482 166 460 175 0.003 239 0.005 -15.013 0.068 SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 297 329 323 303 432 0.006 499 0.007 -9.586 0.066 Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 317 309 343 283 563 0.010 618 0.011 -7.786 0.065 OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 322 304 348 278 557 0.008 639 0.009 -10.380 0.065 TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 1 625 3 623 1 0.000 3 0.000 -5.233 0.064 GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 505 121 525 101 1636 0.019 1748 0.021 -7.764 0.062 MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 147 479 170 456 178 0.003 201 0.003 -5.187 0.061 ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 5 621 10 616 5 0.000 10 0.000 -6.567 0.060 Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 125 501 147 479 142 0.003 175 0.004 -9.731 0.059 mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 134 492 157 469 181 0.003 221 0.004 -8.990 0.056 FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 597 29 607 19 4254 0.044 5285 0.054 -38.748 0.054 Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 23 603 34 592 23 0.001 37 0.001 -9.532 0.053 PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 60 566 77 549 65 0.001 94 0.001 -9.505 0.053 POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 160 466 185 441 222 0.003 271 0.004 -9.483 0.051 TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 551 75 568 58 1915 0.028 2115 0.031 -14.100 0.050 Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 544 82 562 64 2506 0.029 3247 0.038 -37.637 0.048 LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 292 334 321 305 482 0.007 570 0.008 -11.774 0.046 POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 325 301 354 272 716 0.009 908 0.012 -19.309 0.045 Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 257 369 286 340 378 0.004 438 0.005 -8.188 0.045 RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 10 616 18 608 10 0.000 18 0.000 -7.585 0.043 FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 415 211 443 183 929 0.020 1076 0.024 -17.677 0.040 RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 7 619 14 612 7 0.000 14 0.000 -7.528 0.039 Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 22 604 34 592 23 0.001 34 0.001 -7.588 0.038 BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 173 453 201 425 219 0.003 272 0.004 -10.234 0.037 HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 53 573 71 555 58 0.001 82 0.002 -9.604 0.037 DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 530 96 551 75 2271 0.027 2950 0.035 -36.116 0.036 GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 2 624 6 620 2 0.000 6 0.000 -6.589 0.035 SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 14 612 24 602 14 0.000 26 0.001 -9.156 0.035 POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 240 386 271 355 425 0.006 556 0.007 -16.792 0.033 Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 3 623 8 618 3 0.000 9 0.000 -8.295 0.033 HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 136 490 163 463 164 0.003 196 0.003 -7.642 0.032 Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 13 613 23 603 13 0.000 24 0.001 -9.299 0.031 HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 266 360 298 328 426 0.008 496 0.009 -11.007 0.031 Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 470 156 497 129 1700 0.015 2354 0.021 -33.463 0.030 NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 530 96 552 74 1269 0.019 1331 0.020 -5.533 0.029 CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 176 450 206 420 224 0.003 253 0.004 -5.829 0.029 ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 65 561 86 540 71 0.001 95 0.002 -8.928 0.028 HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 364 262 397 229 717 0.011 813 0.012 -10.793 0.025 Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 529 97 552 74 2349 0.024 2899 0.030 -27.559 0.024 TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 123 503 151 475 163 0.003 191 0.003 -7.080 0.024 HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 410 216 442 184 983 0.014 1269 0.019 -25.723 0.023 OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 184 442 216 410 247 0.004 320 0.005 -12.989 0.023 POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 255 371 290 336 397 0.006 513 0.008 -16.321 0.020 Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 446 180 477 149 1337 0.027 1299 0.027 3.871 0.020 PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 489 137 517 109 1605 0.019 2229 0.026 -37.990 0.020 HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 162 464 194 432 200 0.003 242 0.004 -9.024 0.019 GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 453 173 484 142 1079 0.016 1470 0.022 -32.702 0.019 PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 494 132 522 104 1210 0.016 1518 0.020 -24.057 0.018 SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 432 194 465 161 1158 0.015 1520 0.020 -28.237 0.017 Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 53 573 75 551 55 0.001 82 0.002 -12.348 0.016 VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 398 228 433 193 862 0.011 1237 0.016 -32.337 0.016 CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 193 433 228 398 249 0.004 287 0.004 -7.162 0.016 TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 1 625 5 621 1 0.000 5 0.000 -7.648 0.016 RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 1 625 5 621 1 0.000 5 0.000 -7.648 0.016 POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 52 574 74 552 58 0.001 94 0.002 -13.947 0.015 PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 86 540 113 513 100 0.001 148 0.002 -12.532 0.015 EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 514 112 541 85 1802 0.021 2350 0.028 -32.538 0.015 FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 382 244 418 208 786 0.009 930 0.011 -13.507 0.015 POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 193 433 229 397 289 0.006 364 0.007 -14.286 0.014 BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 549 77 572 54 2375 0.028 3249 0.038 -44.352 0.013 RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 30 596 48 578 30 0.001 51 0.001 -11.807 0.013 NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 521 105 548 78 1978 0.029 2695 0.040 -44.700 0.013 Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 504 122 533 93 1858 0.022 2548 0.030 -39.371 0.012 HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 29 597 47 579 31 0.001 51 0.001 -9.744 0.012 DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 176 450 212 414 248 0.004 300 0.005 -10.485 0.012 Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 9 617 20 606 9 0.000 20 0.000 -10.183 0.011 Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 52 574 76 550 58 0.001 81 0.002 -10.589 0.010 Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 23 603 40 586 23 0.001 40 0.001 -10.453 0.010 HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 89 537 119 507 98 0.002 151 0.003 -16.778 0.009 HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 198 428 237 389 268 0.004 338 0.005 -12.720 0.009 EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 469 157 503 123 1288 0.019 1777 0.026 -37.279 0.009 CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 446 180 482 144 971 0.016 1194 0.019 -21.712 0.008 POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 54 572 79 547 64 0.001 96 0.002 -12.273 0.008 NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 128 498 163 463 170 0.003 207 0.003 -8.593 0.008 REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 1 625 6 620 1 0.000 6 0.000 -9.405 0.008 CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 362 264 403 223 716 0.012 944 0.015 -24.887 0.007 HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 390 236 430 196 883 0.013 1435 0.021 -46.665 0.007 Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 398 228 438 188 687 0.010 760 0.011 -8.501 0.007 Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 7 619 18 608 7 0.000 18 0.000 -10.084 0.007 Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 169 457 208 418 219 0.004 271 0.005 -11.024 0.007 Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 434 192 472 154 798 0.009 928 0.011 -12.214 0.007 POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 207 419 248 378 342 0.006 442 0.008 -16.606 0.007 SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 163 463 202 424 205 0.003 266 0.004 -11.901 0.006 MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 316 310 359 267 575 0.013 860 0.019 -38.091 0.006 Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 445 181 483 143 939 0.012 1118 0.015 -16.268 0.006 LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 418 208 458 168 1087 0.013 1388 0.016 -23.130 0.006 FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 284 342 328 298 553 0.009 763 0.012 -25.448 0.005 TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 566 60 589 37 1760 0.021 2122 0.025 -22.621 0.005 Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 315 311 359 267 694 0.011 998 0.016 -32.261 0.005 POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 23 603 42 584 23 0.001 44 0.001 -12.707 0.005 PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 105 521 140 486 121 0.002 192 0.003 -17.065 0.005 RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 413 213 455 171 1061 0.016 1591 0.023 -42.618 0.004 Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 82 544 115 511 91 0.002 140 0.003 -14.995 0.004 OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 154 472 195 431 187 0.003 269 0.004 -15.891 0.004 BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 101 525 137 489 115 0.002 173 0.003 -15.344 0.004 Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 376 250 421 205 840 0.009 1134 0.012 -23.310 0.003 MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 399 227 443 183 863 0.013 1060 0.016 -19.374 0.003 HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 387 239 432 194 804 0.012 1190 0.017 -35.785 0.003 Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 171 455 215 411 203 0.004 289 0.005 -17.623 0.003 DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 183 443 228 398 239 0.004 339 0.005 -18.118 0.003 CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 306 320 354 272 421 0.005 545 0.006 -15.132 0.003 LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 418 208 462 164 1163 0.015 1637 0.022 -35.631 0.003 TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 25 601 47 579 26 0.001 49 0.001 -13.986 0.002 PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 187 439 233 393 220 0.006 343 0.010 -29.154 0.002 Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 209 417 257 369 329 0.005 462 0.007 -20.661 0.002 YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 136 490 179 447 151 0.002 223 0.004 -16.067 0.002 Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 117 509 158 468 132 0.004 186 0.005 -17.358 0.002 Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 165 461 211 415 224 0.004 328 0.005 -19.150 0.002 Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 340 286 390 236 707 0.012 1079 0.019 -39.698 0.002 NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 481 145 522 104 1704 0.020 2146 0.025 -27.444 0.001 VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 402 224 451 175 1037 0.012 1472 0.017 -32.438 0.001 SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 322 304 375 251 536 0.007 673 0.009 -15.983 0.001 HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 227 399 280 346 329 0.005 466 0.007 -20.198 0.001 CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 365 261 418 208 680 0.010 813 0.012 -14.919 0.001 ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 428 198 477 149 1060 0.012 1541 0.018 -35.064 0.001 CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 451 175 498 128 1532 0.020 2155 0.029 -40.959 0.001 CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 304 322 359 267 502 0.007 615 0.009 -14.545 0.001 FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 266 360 321 305 441 0.010 623 0.014 -28.516 0.001 VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 356 270 410 216 743 0.009 1110 0.013 -31.438 0.001 MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 105 521 150 476 120 0.002 180 0.003 -14.204 0.001 CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 356 270 411 215 657 0.010 784 0.012 -14.505 0.001 PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 190 436 244 382 289 0.005 423 0.007 -21.742 0.001 HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 340 286 396 230 687 0.010 1078 0.016 -38.042 0.001 Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 368 258 423 203 767 0.009 1032 0.012 -23.551 0.001 LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 421 205 473 153 929 0.014 1261 0.019 -29.935 0.000 PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 443 183 493 133 1374 0.016 1982 0.023 -39.186 0.000 POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 183 443 238 388 289 0.005 421 0.007 -22.430 0.000 JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 237 389 295 331 321 0.007 432 0.010 -20.852 0.000 Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 120 506 173 453 140 0.003 223 0.006 -23.034 0.000 JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 255 371 319 307 336 0.006 473 0.009 -22.882 0.000 POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 127 499 183 443 185 0.003 262 0.005 -16.569 0.000 Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 400 226 462 164 1209 0.018 1733 0.025 -40.426 0.000 HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 366 260 431 195 911 0.015 1297 0.021 -36.023 0.000 Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 16 610 45 581 17 0.000 46 0.001 -17.675 0.000 ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 46 580 89 537 52 0.001 119 0.002 -23.047 0.000 MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 439 187 500 126 1438 0.021 2036 0.030 -42.665 0.000 POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 109 517 168 458 155 0.003 238 0.005 -19.493 0.000 DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 321 305 393 233 585 0.009 928 0.015 -37.706 0.000 HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 309 317 387 239 585 0.009 917 0.013 -34.982 0.000 CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 103 523 177 449 117 0.002 259 0.004 -27.998 0.000 MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 154 472 237 389 200 0.004 400 0.007 -34.818 0.000 GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 517 109 576 50 1951 0.023 2456 0.029 -29.365 0.000 ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 32 594 88 538 35 0.001 115 0.002 -27.982 0.000 ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 39 587 99 527 43 0.001 133 0.003 -29.277 0.000 YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 202 424 300 326 244 0.004 419 0.007 -29.783 0.000 CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 124 502 216 410 153 0.002 334 0.005 -31.442 0.000 Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 148 478 245 381 214 0.004 390 0.008 -33.539 0.000 MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 126 500 223 403 155 0.003 362 0.006 -37.859 0.000 MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 82 544 178 448 92 0.002 247 0.004 -34.282 0.000 RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 626 0 626 0 8532 0.100 8728 0.103 -6.512 0.000 NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 0 626 2 624 0 0.000 2 0.000 -5.919 0.000 SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 0 626 0 626 0 0.000 0 0.000 NA 0.000