Human Analysis


Summary

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Job ID: FF:11231-116C7
Number of target experiments: 1
Number of target CAGE peaks: 1069
Number of target CAGE peak regions: 745
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 745
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:11231-116C7 Peripheral Blood Mononuclear Cells, donor1


Results

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Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 687 58 540 205 1841 0.0228 1309 0.0163 46.744 54.845
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 648 97 493 252 1507 0.0206 1040 0.0142 48.242 48.772
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 582 163 421 324 1096 0.0136 749 0.0093 40.174 42.704
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 658 87 526 219 1497 0.0186 999 0.0124 50.012 39.289
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 617 128 472 273 1266 0.0157 843 0.0105 46.198 39.052
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 665 80 540 205 1644 0.0204 1152 0.0143 46.041 37.323
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 628 117 492 253 1307 0.0162 892 0.0111 44.069 36.387
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 613 132 475 270 1278 0.0159 833 0.0103 48.895 35.480
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 599 146 460 285 1193 0.0148 834 0.0104 39.404 34.503
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 517 228 375 370 909 0.0124 650 0.00888 33.740 30.916
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 393 352 254 491 542 0.00672 324 0.00402 38.294 29.090
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 129 616 42 703 138 0.0024 46 0.0008 50.706 28.332
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 460 285 325 420 707 0.00877 496 0.00616 29.964 27.183
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 298 447 190 555 391 0.00534 228 0.00311 35.784 20.272
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 703 42 637 108 2258 0.0308 1601 0.0219 54.906 18.807
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 636 109 555 190 2613 0.0389 2090 0.0311 40.085 16.119
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 631 114 551 194 2406 0.0358 1947 0.029 36.400 15.462
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 316 429 224 521 429 0.00532 296 0.00368 24.418 14.616
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 218 527 139 606 268 0.00465 162 0.00282 31.134 13.791
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 534 211 448 297 1238 0.0323 871 0.0227 57.482 13.325
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 645 100 577 168 1617 0.0221 1284 0.0175 30.962 12.773
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 509 236 426 319 1286 0.016 1062 0.0132 21.767 12.126
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 596 149 525 220 2189 0.0299 1737 0.0237 36.249 11.271
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 176 569 112 633 195 0.0029 129 0.00192 20.089 10.988
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 484 261 405 340 863 0.0107 656 0.00815 25.566 10.889
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 668 77 613 132 4259 0.0634 3543 0.0528 42.590 10.560
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 356 389 280 465 485 0.00602 350 0.00435 22.793 10.074
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 577 168 509 236 2702 0.0369 2362 0.0323 23.415 9.988
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 351 394 276 469 502 0.00623 395 0.0049 16.990 9.887
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 379 366 304 441 694 0.0112 537 0.00867 24.436 9.739
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 494 251 425 320 781 0.00969 632 0.00785 18.725 8.848
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 372 373 305 440 635 0.0102 510 0.00823 19.946 8.128
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 141 604 92 653 149 0.00222 104 0.00155 15.242 8.118
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 686 59 645 100 2384 0.0384 1869 0.0302 43.439 7.890
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 288 457 226 519 390 0.00726 300 0.00559 20.100 7.732
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 302 443 241 504 426 0.00793 306 0.0057 26.559 7.395
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 563 182 507 238 1525 0.0227 1320 0.0197 19.606 7.180
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 127 618 86 659 148 0.00257 98 0.0017 18.856 6.501
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 151 594 108 637 163 0.00243 121 0.0018 13.183 6.207
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 202 543 154 591 280 0.0059 222 0.00469 16.013 6.152
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 547 198 496 249 983 0.011 837 0.00935 15.114 6.059
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 141 604 100 645 158 0.00274 114 0.00198 15.376 6.029
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 397 348 343 402 593 0.00809 527 0.0072 9.486 5.807
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 81 664 52 693 90 0.00134 54 0.000805 16.925 5.228
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 72 673 45 700 81 0.00141 45 0.000782 20.034 5.116
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 700 45 673 72 2777 0.0379 2263 0.0309 36.229 5.116
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 629 116 591 154 1676 0.0208 1549 0.0192 10.175 5.057
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 498 247 451 294 937 0.0163 804 0.014 17.559 5.023
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 199 546 158 587 255 0.00474 191 0.00356 17.898 4.885
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 645 100 610 135 3010 0.0411 2480 0.0339 35.730 4.858
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 493 252 447 298 865 0.0161 713 0.0133 22.080 4.850
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 667 78 636 109 2022 0.0276 1653 0.0226 30.298 4.667
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 278 467 234 511 351 0.00479 298 0.00407 10.135 4.659
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 70 675 45 700 74 0.00138 47 0.000875 15.208 4.631
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 333 412 288 457 585 0.00943 465 0.00751 20.049 4.569
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 663 82 632 113 1664 0.0186 1597 0.0178 4.953 4.556
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 499 246 456 289 926 0.0126 822 0.0112 11.996 4.453
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 273 472 231 514 350 0.00651 294 0.00548 12.607 4.393
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 294 451 252 493 428 0.00796 378 0.00704 9.912 4.288
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 684 61 658 87 2752 0.0341 2101 0.0261 45.345 4.197
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 395 350 353 392 659 0.00981 547 0.00815 16.565 4.086
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 394 351 353 392 618 0.0092 534 0.00796 12.553 3.959
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 24 721 11 734 25 0.000434 15 0.000261 9.609 3.947
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 491 254 452 293 2106 0.0287 1866 0.0255 18.515 3.886
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 607 138 576 169 1673 0.0228 1378 0.0188 26.473 3.602
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 245 500 211 534 303 0.00376 255 0.00317 9.458 3.450
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 86 659 64 681 94 0.00152 69 0.00111 10.807 3.348
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 220 525 188 557 262 0.00455 224 0.00389 9.451 3.329
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 279 466 245 500 468 0.00639 402 0.00549 10.871 3.306
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 615 130 587 158 2838 0.0528 2268 0.0422 47.161 3.265
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 692 53 672 73 2172 0.0216 2209 0.0219 -2.383 3.263
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 691 54 671 74 2815 0.0349 2835 0.0352 -1.376 3.236
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 469 276 435 310 874 0.0108 727 0.00903 17.223 3.218
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 592 153 563 182 1420 0.0176 1179 0.0146 22.240 3.192
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 115 630 91 654 135 0.00268 108 0.00215 10.347 3.169
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 475 270 442 303 827 0.0113 831 0.0114 -0.560 3.120
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 266 479 234 511 352 0.00524 302 0.0045 9.919 3.113
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 238 507 207 538 306 0.00569 263 0.0049 10.221 3.108
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 679 66 659 86 2011 0.0249 1906 0.0237 7.556 2.960
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 594 151 567 178 1669 0.0228 1399 0.0191 24.038 2.954
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 342 403 310 435 468 0.00871 423 0.00788 8.421 2.943
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 80 665 61 684 84 0.00198 64 0.00151 10.853 2.893
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 22 723 12 733 22 0.000409 13 0.000242 9.615 2.837
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 179 566 153 592 209 0.00259 173 0.00215 8.609 2.817
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 44 701 30 715 46 0.000856 30 0.000559 11.268 2.809
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 167 578 142 603 211 0.00445 161 0.0034 16.208 2.772
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 99 646 79 666 112 0.00167 87 0.0013 9.240 2.742
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 46 699 32 713 47 0.000875 33 0.000615 9.393 2.733
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 735 10 726 19 4746 0.0412 3808 0.0331 40.718 2.716
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 250 495 222 523 344 0.0064 295 0.00549 11.003 2.713
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 40 705 27 718 41 0.000865 28 0.000591 10.084 2.710
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 235 510 208 537 296 0.00404 241 0.00329 11.705 2.655
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 85 660 67 678 89 0.00221 73 0.00181 8.329 2.621
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 90 655 72 673 101 0.00175 78 0.00136 9.699 2.545
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 92 653 74 671 103 0.00153 80 0.00119 8.863 2.517
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 698 47 683 62 2565 0.0318 2669 0.0331 -6.633 2.505
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 698 47 683 62 3620 0.0494 3185 0.0435 25.941 2.505
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 27 718 17 728 27 0.000402 17 0.000253 8.350 2.478
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 205 540 181 564 251 0.00436 230 0.004 5.126 2.443
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 98 647 81 664 103 0.00166 85 0.00137 6.994 2.291
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 600 145 579 166 1316 0.0163 1199 0.0149 10.650 2.291
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 11 734 5 740 11 0.000218 5 9.93e-05 10.664 2.265
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 265 480 241 504 339 0.00421 318 0.00395 3.667 2.262
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 728 17 719 26 7555 0.0937 6261 0.0777 53.573 2.229
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 41 704 30 715 42 0.000886 30 0.000633 8.988 2.191
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 645 100 628 117 1725 0.0235 1583 0.0216 11.830 2.121
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 672 73 657 88 4169 0.0724 3521 0.0612 41.930 2.109
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 139 606 121 624 164 0.00203 136 0.00169 7.547 2.096
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 745 0 742 3 6220 0.0694 6273 0.0701 -2.318 2.081
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 345 400 323 422 506 0.00753 462 0.00688 7.034 1.988
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 701 44 690 55 2127 0.0211 2129 0.0211 -0.254 1.903
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 677 68 664 81 2086 0.0285 1895 0.0259 14.594 1.897
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 488 257 468 277 912 0.0113 818 0.0102 10.349 1.882
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 731 14 724 21 3363 0.0334 3364 0.0334 -0.212 1.881
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 588 157 571 174 1275 0.0127 1314 0.0131 -3.165 1.837
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 60 685 49 696 66 0.000982 51 0.00076 7.231 1.833
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 296 449 277 468 508 0.00882 434 0.00754 13.254 1.778
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 80 665 68 677 82 0.00142 71 0.00123 4.839 1.770
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 99 646 86 659 105 0.00156 95 0.00142 3.508 1.755
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 672 73 660 85 2390 0.0296 2165 0.0269 15.348 1.730
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 151 594 136 609 204 0.0038 183 0.00341 5.960 1.721
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 744 1 741 4 7012 0.0522 6697 0.0499 9.469 1.676
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 394 351 376 369 582 0.00722 554 0.00688 3.695 1.666
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 640 105 627 118 1515 0.0188 1556 0.0193 -3.442 1.651
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 8 737 4 741 8 0.000139 4 6.95e-05 7.406 1.646
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 720 25 713 32 5449 0.0473 6313 0.0549 -29.789 1.566
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 9 736 5 740 9 0.000201 6 0.000134 5.136 1.557
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 609 136 596 149 1461 0.0145 1304 0.013 12.269 1.539
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 693 52 684 61 2548 0.0348 2453 0.0335 6.305 1.528
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 404 341 388 357 748 0.0102 666 0.0091 10.494 1.523
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 561 184 547 198 1070 0.0106 1068 0.0106 0.080 1.513
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 63 682 54 691 65 0.00105 54 0.000872 5.353 1.512
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 185 560 172 573 217 0.0035 199 0.00321 4.547 1.456
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 361 384 346 399 573 0.0107 517 0.00963 9.490 1.453
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 699 46 691 54 2449 0.0182 2536 0.0189 -4.393 1.451
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 333 412 319 426 542 0.00941 474 0.00824 11.645 1.392
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 107 638 97 648 116 0.00201 111 0.00193 1.726 1.391
*SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 2 743 0 745 2 3.97e-05 0 0 NA 1.387
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 46 699 39 706 48 0.000893 40 0.000745 4.855 1.380
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 6 739 3 742 6 0.000134 3 6.71e-05 7.270 1.373
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 742 3 739 6 4378 0.0489 4285 0.0479 4.171 1.373
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 502 243 489 256 1031 0.0115 1007 0.0113 2.184 1.366
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 37 708 31 714 38 0.000707 31 0.000577 4.825 1.318
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 693 52 686 59 3907 0.0485 4576 0.0568 -32.400 1.284
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 329 416 317 428 471 0.00818 447 0.00777 4.180 1.264
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 338 407 326 419 494 0.00613 482 0.00599 1.659 1.262
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 18 727 14 731 18 0.000313 14 0.000243 3.949 1.216
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 460 285 449 296 720 0.00893 729 0.00905 -1.146 1.212
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 3 742 1 744 3 5.58e-05 1 1.86e-05 7.610 1.164
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 91 654 84 661 103 0.00166 93 0.0015 3.692 1.156
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 463 282 453 292 843 0.0115 869 0.0119 -3.040 1.152
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 658 87 651 94 1942 0.0241 2013 0.025 -5.206 1.148
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 68 677 62 683 81 0.00181 88 0.00197 -3.218 1.130
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 706 39 701 44 2422 0.024 2347 0.0233 4.292 1.121
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 25 720 21 724 25 0.000434 21 0.000365 3.219 1.118
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 502 243 493 252 868 0.0108 910 0.0113 -4.523 1.109
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 638 107 631 114 1483 0.0147 1586 0.0158 -7.483 1.106
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 186 559 178 567 225 0.00279 212 0.00263 2.771 1.089
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 511 234 503 242 880 0.0109 879 0.0109 0.012 1.054
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 505 240 497 248 1168 0.0217 1258 0.0234 -10.077 1.051
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 100 645 94 651 115 0.003 110 0.00287 2.130 1.049
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 173 572 166 579 217 0.00404 234 0.00436 -4.377 1.034
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 305 440 297 448 406 0.00504 398 0.00494 1.202 1.033
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 19 726 16 729 19 0.000424 17 0.00038 2.012 1.004
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 694 51 690 55 3407 0.0338 4298 0.0427 -39.453 0.964
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 7 738 5 740 7 0.000122 5 8.69e-05 3.277 0.950
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 7 738 5 740 7 0.000182 5 0.00013 4.039 0.950
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 674 71 670 75 3990 0.0495 3365 0.0418 34.608 0.924
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 215 530 210 535 279 0.00277 258 0.00256 3.646 0.893
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 508 237 503 242 1061 0.0145 1046 0.0143 1.441 0.886
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 702 43 699 46 5643 0.077 4584 0.0626 53.331 0.883
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 701 44 698 47 2331 0.0289 2464 0.0306 -8.757 0.881
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 121 624 117 628 164 0.00285 150 0.00261 4.226 0.877
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 305 440 300 445 417 0.00414 400 0.00397 2.345 0.876
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 698 47 695 50 2685 0.0233 3034 0.0264 -17.126 0.875
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 51 694 48 697 52 0.000774 54 0.000805 -0.987 0.873
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 667 78 664 81 1879 0.0233 1858 0.0231 1.422 0.836
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 43 702 41 704 44 0.000655 45 0.000671 -0.560 0.787
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 684 61 682 63 4289 0.0585 3871 0.0529 22.680 0.771
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 64 681 62 683 74 0.00119 65 0.00105 3.980 0.770
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 86 659 84 661 94 0.00175 94 0.00175 -0.049 0.760
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 107 638 105 640 122 0.00166 120 0.00164 0.557 0.754
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 4 741 3 742 4 6.45e-05 4 6.46e-05 -0.076 0.693
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 34 711 33 712 34 0.000717 34 0.000718 -0.044 0.693
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 180 565 179 566 227 0.00197 209 0.00182 3.246 0.693
*BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 1 744 0 745 1 2.11e-05 0 0 NA 0.693
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 744 1 743 2 6320 0.0706 6268 0.07 1.805 0.693
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 646 99 645 100 1958 0.017 1937 0.0168 1.156 0.693
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 32 713 31 714 33 0.000491 34 0.000507 -0.638 0.693
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 6 739 5 740 6 0.000104 5 8.69e-05 1.605 0.693
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 10 735 9 736 10 0.000186 9 0.000168 1.236 0.693
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 12 733 11 734 12 0.000268 13 0.000291 -1.224 0.693
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 6 739 5 740 7 0.000148 5 0.000106 3.623 0.693
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 10 735 9 736 10 0.000186 9 0.000168 1.236 0.693
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 2 743 1 744 2 3.97e-05 1 1.99e-05 3.869 0.693
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 549 196 549 196 1065 0.0132 1131 0.014 -6.354 0.647
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 278 467 279 466 360 0.00581 335 0.00541 4.865 0.611
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 713 32 713 32 2781 0.0345 2687 0.0334 5.667 0.596
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 28 717 28 717 29 0.000504 32 0.000556 -2.028 0.590
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 619 126 620 125 2125 0.0211 2122 0.0211 0.056 0.589
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 26 719 26 719 26 0.000548 27 0.00057 -0.837 0.587
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 643 102 644 101 1608 0.0219 1656 0.0226 -4.089 0.580
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 99 646 100 645 112 0.00195 110 0.00191 0.664 0.579
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 20 725 20 725 20 0.000397 21 0.000417 -0.917 0.574
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 88 657 89 656 95 0.00177 110 0.00205 -5.593 0.573
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 218 527 220 525 278 0.00414 315 0.00469 -7.302 0.566
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 16 729 16 729 16 0.000337 16 0.000338 -0.046 0.561
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 679 66 680 65 2987 0.0259 3301 0.0287 -14.815 0.558
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 339 406 342 403 540 0.00536 543 0.00539 -0.436 0.541
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 424 321 427 318 734 0.0127 734 0.0128 -0.102 0.540
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 459 286 462 283 784 0.00778 783 0.00778 0.019 0.537
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 484 261 487 258 1028 0.0102 1101 0.0109 -6.349 0.534
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 10 735 10 735 10 0.000186 10 0.000186 -0.053 0.530
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 660 85 662 83 2653 0.0362 2522 0.0344 8.635 0.516
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 395 350 399 346 694 0.0103 771 0.0115 -9.755 0.507
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 613 132 616 129 1989 0.0197 2362 0.0235 -22.093 0.499
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 23 722 24 721 23 0.000485 25 0.000528 -1.693 0.484
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 702 43 704 41 2551 0.0285 2979 0.0333 -24.077 0.459
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 127 618 131 614 142 0.00264 151 0.00281 -2.895 0.456
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 38 707 40 705 39 0.000774 42 0.000834 -1.896 0.452
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 627 118 631 114 1613 0.02 1715 0.0213 -8.000 0.447
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 15 730 16 729 15 0.000298 17 0.000338 -1.986 0.444
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 3 742 3 742 3 6.7e-05 3 6.71e-05 -0.075 0.421
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 742 3 742 3 7847 0.0584 6838 0.0509 30.464 0.421
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 615 130 620 125 2135 0.0291 1983 0.0271 11.325 0.415
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 190 555 196 549 231 0.00344 238 0.00355 -1.634 0.415
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 11 734 12 733 11 0.000232 12 0.000253 -1.238 0.412
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 278 467 285 460 365 0.00589 362 0.00584 0.497 0.407
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 41 704 44 701 42 0.000625 45 0.000671 -1.593 0.397
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 146 599 152 593 166 0.00227 182 0.00249 -3.991 0.393
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 448 297 456 289 889 0.00882 979 0.00973 -8.262 0.381
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 8 737 9 736 8 0.000169 9 0.00019 -1.426 0.376
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 474 271 482 263 815 0.0101 834 0.0104 -2.184 0.376
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 32 713 35 710 33 0.000573 38 0.000661 -3.078 0.369
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 78 667 83 662 80 0.00169 102 0.00215 -9.039 0.369
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 582 163 589 156 1606 0.0139 1743 0.0152 -8.855 0.366
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 105 640 111 634 114 0.00156 125 0.00171 -3.313 0.361
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 7 738 8 737 7 0.000148 8 0.000169 -1.511 0.361
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 16 729 18 727 17 0.000295 18 0.000313 -0.928 0.359
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 637 108 643 102 1836 0.0182 2314 0.023 -28.556 0.358
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 599 146 606 139 1570 0.0156 1792 0.0178 -15.079 0.355
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 46 699 50 695 48 0.00101 53 0.00112 -2.877 0.355
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 14 731 16 729 20 0.000447 16 0.000358 4.196 0.343
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 87 658 93 652 90 0.00112 105 0.0013 -4.676 0.341
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 507 238 516 229 901 0.00894 957 0.00951 -5.232 0.340
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 654 91 660 85 2413 0.021 2673 0.0232 -13.592 0.338
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 360 385 370 375 525 0.00716 535 0.00731 -1.519 0.335
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 310 435 320 425 556 0.00828 560 0.00834 -0.673 0.331
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 455 290 465 280 929 0.0115 926 0.0115 0.216 0.327
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 174 571 183 562 211 0.00314 225 0.00335 -3.296 0.317
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 506 239 516 229 897 0.0122 943 0.0129 -5.101 0.314
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 385 360 396 349 595 0.00664 629 0.00703 -4.158 0.310
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 30 715 34 711 31 0.000538 34 0.000591 -1.968 0.303
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 10 735 12 733 10 0.000198 12 0.000238 -2.358 0.301
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 239 506 250 495 293 0.00473 317 0.00512 -4.940 0.293
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 104 641 112 633 111 0.00165 127 0.00189 -4.971 0.293
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 4 741 5 740 4 9.92e-05 5 0.000124 -2.059 0.292
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 76 669 83 662 83 0.00165 90 0.00179 -3.002 0.289
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 9 736 11 734 9 0.00019 11 0.000232 -2.535 0.288
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 359 386 371 374 551 0.0082 630 0.00939 -11.039 0.288
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 1 744 1 744 1 1.98e-05 1 1.99e-05 -0.129 0.287
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 201 544 212 533 250 0.00279 279 0.00312 -5.272 0.279
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 489 256 501 244 880 0.012 882 0.012 -0.324 0.272
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 227 518 239 506 283 0.00351 301 0.00374 -3.347 0.266
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 172 573 183 562 205 0.0028 228 0.00311 -5.115 0.265
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 7 738 9 736 7 0.000148 9 0.00019 -2.800 0.256
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 581 164 592 153 1195 0.0148 1290 0.016 -8.542 0.253
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 28 717 33 712 30 0.00067 34 0.00076 -2.954 0.244
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 466 279 480 265 951 0.013 1072 0.0146 -12.451 0.235
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 691 54 698 47 4001 0.0347 4704 0.0409 -27.857 0.229
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 321 424 336 409 445 0.00828 503 0.00937 -10.148 0.226
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 2 743 3 742 2 5.21e-05 3 7.82e-05 -2.715 0.207
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 416 329 432 313 687 0.00852 731 0.00908 -5.255 0.207
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 39 706 46 699 44 0.000873 49 0.000973 -2.902 0.206
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 637 108 648 97 2569 0.0319 3273 0.0406 -39.889 0.203
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 76 669 86 659 79 0.00167 91 0.00192 -5.239 0.198
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 196 549 211 534 238 0.00384 300 0.00484 -12.999 0.194
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 355 390 372 373 520 0.00968 614 0.0114 -14.867 0.193
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 678 67 687 58 2087 0.0207 2429 0.0241 -19.997 0.192
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 664 81 674 71 3128 0.031 3743 0.0372 -29.134 0.190
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 543 202 558 187 1174 0.0146 1273 0.0158 -8.954 0.190
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 25 720 31 714 25 0.000527 31 0.000654 -4.486 0.187
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 55 690 64 681 62 0.00115 72 0.00134 -4.612 0.186
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 17 728 22 723 17 0.000359 22 0.000464 -4.438 0.181
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 23 722 29 716 23 0.000485 29 0.000612 -4.637 0.176
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 489 256 506 239 833 0.0114 888 0.0121 -6.256 0.176
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 16 729 21 724 16 0.000278 21 0.000365 -4.127 0.173
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 627 118 640 105 2087 0.0207 2564 0.0255 -27.120 0.168
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 423 322 442 303 696 0.0095 683 0.00933 1.568 0.159
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 681 64 691 54 2369 0.0294 2408 0.0299 -2.704 0.157
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 726 19 731 14 3246 0.0403 2980 0.037 15.524 0.157
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 14 731 19 726 14 0.000261 19 0.000354 -4.487 0.157
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 555 190 572 173 1241 0.0139 1356 0.0152 -9.547 0.149
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 184 561 202 543 228 0.00311 297 0.00406 -13.363 0.140
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 636 109 650 95 2501 0.0248 2886 0.0287 -20.708 0.138
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 468 277 488 257 799 0.0109 818 0.0112 -2.311 0.137
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 1 744 2 743 1 2.11e-05 2 4.22e-05 -3.005 0.133
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 71 674 84 661 78 0.00164 92 0.00194 -6.072 0.125
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 48 697 59 686 52 0.000903 64 0.00111 -5.658 0.121
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 307 438 329 416 529 0.00591 639 0.00714 -13.175 0.121
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 497 248 518 227 874 0.00867 996 0.00989 -11.075 0.117
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 543 202 563 182 1577 0.0176 1908 0.0213 -23.099 0.113
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 29 716 38 707 31 0.000654 38 0.000802 -4.726 0.111
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 17 728 24 721 18 0.000313 27 0.000469 -6.523 0.108
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 604 141 622 123 1488 0.0166 1892 0.0211 -28.280 0.104
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 351 394 375 370 549 0.0102 590 0.011 -6.666 0.103
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 104 641 121 624 111 0.00248 134 0.00299 -8.496 0.101
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 406 339 430 315 603 0.00598 715 0.0071 -11.963 0.101
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 575 170 595 150 1607 0.0159 1713 0.017 -7.420 0.097
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 265 480 289 456 411 0.0051 406 0.00504 0.717 0.094
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 145 600 165 580 167 0.00228 212 0.0029 -10.317 0.094
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 697 48 708 37 2389 0.0237 2499 0.0248 -6.440 0.094
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 333 412 358 387 536 0.00532 646 0.00642 -12.351 0.093
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 36 709 47 698 36 0.000625 48 0.000834 -6.524 0.092
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 36 709 47 698 38 0.00066 51 0.000887 -6.855 0.092
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 440 305 465 280 677 0.0084 746 0.00926 -8.111 0.088
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 41 704 53 692 45 0.000782 60 0.00104 -7.291 0.086
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 323 422 349 396 457 0.00567 536 0.00666 -10.899 0.083
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 26 719 36 709 28 0.000556 40 0.000795 -7.633 0.080
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 16 729 24 721 16 0.000318 24 0.000477 -6.575 0.077
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 342 403 369 376 464 0.00748 547 0.00883 -12.933 0.076
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 317 428 344 401 433 0.0043 482 0.00479 -6.392 0.075
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 77 668 94 651 89 0.00144 117 0.00189 -9.388 0.074
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 411 334 438 307 920 0.0103 1125 0.0126 -18.545 0.074
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 305 440 332 413 419 0.0052 461 0.00572 -6.273 0.074
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 304 441 331 414 394 0.00538 437 0.00597 -6.913 0.074
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 245 500 271 474 343 0.00468 401 0.00548 -9.699 0.073
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 652 93 669 76 2140 0.0212 2570 0.0255 -24.434 0.073
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 663 82 679 66 3025 0.03 4042 0.0402 -46.338 0.073
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 233 512 259 486 325 0.00484 360 0.00536 -6.475 0.071
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 525 220 550 195 1613 0.022 2037 0.0278 -31.734 0.069
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 11 734 18 727 11 0.000164 20 0.000298 -7.016 0.068
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 635 110 654 91 2894 0.0287 3688 0.0366 -37.829 0.067
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 2 743 5 740 2 3.97e-05 5 9.93e-05 -5.429 0.064
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 486 259 513 232 1234 0.0184 1573 0.0234 -30.085 0.063
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 76 669 94 651 87 0.00151 105 0.00183 -6.625 0.063
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 523 222 549 196 1540 0.0267 1545 0.0269 -0.628 0.062
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 397 348 426 319 664 0.00824 773 0.0096 -12.542 0.061
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 308 437 337 408 437 0.00434 517 0.00514 -10.042 0.060
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 54 691 70 675 59 0.00117 76 0.00151 -7.850 0.057
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 153 592 178 567 205 0.00305 234 0.00349 -6.636 0.054
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 313 432 344 401 501 0.00373 534 0.00398 -3.566 0.049
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 713 32 724 21 4569 0.0397 4939 0.0429 -14.416 0.047
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 600 145 624 121 1468 0.0164 1531 0.0171 -4.987 0.046
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 658 87 677 68 2277 0.0282 2428 0.0301 -9.990 0.046
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 427 318 459 286 791 0.00981 991 0.0123 -20.306 0.042
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 133 612 159 586 153 0.00209 189 0.00258 -8.747 0.040
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 142 603 169 576 170 0.00274 214 0.00345 -10.918 0.038
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 436 309 469 276 732 0.00908 780 0.00969 -5.549 0.036
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 111 634 136 609 130 0.00258 165 0.00328 -10.971 0.036
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 642 103 664 81 2552 0.0253 3343 0.0332 -39.497 0.036
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 611 134 636 109 2234 0.0222 2857 0.0284 -33.579 0.035
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 571 174 599 146 1243 0.0139 1272 0.0142 -2.563 0.034
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 251 494 284 461 362 0.00584 444 0.00717 -14.154 0.034
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 211 534 243 502 253 0.00314 325 0.00404 -12.713 0.032
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 629 116 653 92 2963 0.0257 3594 0.0312 -28.437 0.031
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 15 730 26 719 15 0.000298 28 0.000556 -9.869 0.028
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 506 239 539 206 1144 0.0114 1464 0.0145 -23.926 0.027
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 450 295 485 260 825 0.0102 931 0.0116 -11.143 0.027
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 184 561 216 529 254 0.00378 311 0.00463 -11.284 0.027
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 180 565 212 533 224 0.00361 283 0.00457 -12.735 0.026
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 539 206 571 174 1493 0.0148 1835 0.0182 -22.900 0.025
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 118 627 146 599 136 0.00169 162 0.00201 -6.514 0.025
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 347 398 384 361 723 0.00987 920 0.0126 -21.769 0.025
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 297 448 334 411 399 0.00643 481 0.00776 -13.609 0.023
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 510 235 544 201 1015 0.0126 1564 0.0194 -44.435 0.023
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 245 500 281 464 387 0.00576 476 0.00709 -14.254 0.023
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 272 473 309 436 426 0.00634 553 0.00824 -18.861 0.022
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 381 364 419 326 638 0.00871 708 0.00967 -8.854 0.022
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 647 98 671 74 3159 0.0314 3990 0.0396 -38.129 0.021
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 523 222 557 188 1580 0.0176 1948 0.0218 -25.410 0.021
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 531 214 565 180 1225 0.0167 1442 0.0197 -19.259 0.020
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 446 299 484 261 725 0.00899 835 0.0104 -12.188 0.019
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 130 615 161 584 150 0.00335 191 0.00427 -12.672 0.018
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 184 561 219 526 217 0.00296 298 0.00407 -15.650 0.018
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 422 323 461 284 679 0.00927 784 0.0107 -12.593 0.018
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 302 443 342 403 433 0.00537 464 0.00576 -4.635 0.016
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 1 744 5 740 1 2.11e-05 5 0.000106 -7.436 0.016
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 426 319 466 279 848 0.0116 1035 0.0141 -19.514 0.015
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 61 684 85 660 64 0.000953 97 0.00145 -11.657 0.015
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 103 642 133 612 127 0.00205 176 0.00284 -13.386 0.014
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 245 500 285 460 339 0.00463 433 0.00591 -15.093 0.013
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 165 580 201 544 195 0.00411 261 0.00551 -16.954 0.013
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 572 173 606 139 1702 0.0169 2273 0.0226 -34.382 0.013
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 448 297 489 256 844 0.0105 974 0.0121 -13.346 0.012
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 502 243 541 204 1344 0.0133 1555 0.0154 -15.357 0.012
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 285 460 327 418 371 0.0046 456 0.00566 -12.689 0.012
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 282 463 324 421 374 0.00464 412 0.00512 -6.002 0.012
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 353 392 396 349 584 0.00724 763 0.00947 -20.670 0.011
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 467 278 508 237 816 0.0101 909 0.0113 -9.902 0.011
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 572 173 607 138 2187 0.0163 2870 0.0214 -31.684 0.011
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 487 258 528 217 1203 0.0149 1576 0.0196 -30.118 0.010
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 512 233 552 193 1021 0.0139 1370 0.0187 -31.677 0.009
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 99 646 131 614 119 0.00148 178 0.00221 -14.045 0.009
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 156 589 194 551 212 0.00342 266 0.00429 -12.023 0.009
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 30 715 50 695 31 0.000615 55 0.00109 -12.991 0.008
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 552 193 591 154 1949 0.0218 2595 0.029 -38.741 0.007
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 509 236 551 194 1329 0.0165 1976 0.0245 -46.719 0.007
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 515 230 557 188 1602 0.0199 2063 0.0256 -32.642 0.007
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 358 387 405 340 518 0.00643 592 0.00735 -9.729 0.006
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 171 574 212 533 193 0.00263 261 0.00356 -14.039 0.006
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 449 296 495 250 1000 0.00992 1211 0.012 -17.345 0.006
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 578 167 616 129 2204 0.0219 2617 0.026 -23.270 0.006
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 69 676 99 646 79 0.00098 124 0.00154 -12.831 0.005
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 485 260 530 215 811 0.0111 965 0.0132 -16.647 0.005
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 454 291 502 243 1094 0.0095 1402 0.0122 -21.987 0.004
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 150 595 193 552 199 0.00272 274 0.00374 -15.110 0.003
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 395 350 446 299 925 0.0126 1238 0.0169 -29.859 0.003
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 120 625 160 585 133 0.00313 198 0.00467 -20.240 0.003
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 207 538 255 490 275 0.00341 356 0.00442 -13.665 0.003
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 190 555 237 508 239 0.00296 321 0.00399 -14.558 0.003
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 87 658 123 622 94 0.00152 137 0.00221 -13.306 0.003
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 404 341 456 289 720 0.00982 1059 0.0145 -34.895 0.003
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 120 625 161 584 156 0.00213 229 0.00313 -16.075 0.003
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 281 464 333 412 436 0.00541 563 0.00699 -17.056 0.003
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 69 676 103 642 74 0.0011 115 0.00171 -13.298 0.002
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 529 216 577 168 1334 0.0165 1819 0.0226 -36.490 0.002
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 377 368 432 313 622 0.00772 751 0.00933 -15.037 0.002
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 255 490 309 436 414 0.00565 579 0.00791 -22.905 0.002
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 125 620 170 575 154 0.00229 222 0.00331 -15.887 0.001
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 461 284 515 230 1171 0.016 1479 0.0202 -26.949 0.001
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 386 359 443 302 643 0.00718 817 0.00913 -18.426 0.001
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 365 380 423 322 515 0.00831 664 0.0107 -21.046 0.001
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 569 176 616 129 2038 0.0202 2732 0.0271 -38.203 0.001
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 199 546 253 492 281 0.00383 384 0.00524 -17.540 0.001
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 577 168 624 121 2232 0.0222 3071 0.0305 -43.625 0.001
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 338 407 398 347 543 0.0101 761 0.0142 -30.918 0.001
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 219 526 276 469 290 0.0036 421 0.00523 -20.303 0.001
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 537 208 589 156 1741 0.0173 2429 0.0241 -40.088 0.001
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 550 195 601 144 1604 0.0199 2235 0.0278 -42.934 0.001
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 536 209 589 156 1819 0.0226 2551 0.0317 -46.710 0.001
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 463 282 522 223 1030 0.0128 1508 0.0187 -39.398 0.001
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 240 505 300 445 384 0.00524 548 0.00748 -23.393 0.001
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 142 603 196 549 170 0.00211 257 0.00319 -17.239 0.000
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 111 634 161 584 133 0.00247 222 0.00413 -23.235 0.000
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 474 271 535 210 1093 0.0122 1515 0.0169 -32.906 0.000
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 134 611 188 557 155 0.00288 224 0.00417 -17.948 0.000
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 79 666 124 621 92 0.0016 157 0.00273 -19.483 0.000
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 597 148 646 99 2347 0.0233 3153 0.0313 -41.388 0.000
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 1 744 11 734 1 2.23e-05 11 0.000246 -12.836 0.000
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 50 695 88 657 55 0.000819 89 0.00133 -12.533 0.000
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 390 355 456 289 875 0.013 1302 0.0194 -41.502 0.000
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 146 599 203 542 167 0.00207 242 0.003 -15.319 0.000
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 16 729 41 704 17 0.000359 43 0.000908 -16.392 0.000
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 502 243 565 180 1360 0.0135 1834 0.0182 -31.701 0.000
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 185 560 250 495 240 0.00298 328 0.00407 -15.453 0.000
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 503 242 568 177 1145 0.0142 1579 0.0196 -34.990 0.000
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 322 423 395 350 533 0.00661 695 0.00863 -19.593 0.000
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 194 551 262 483 289 0.00359 411 0.0051 -19.139 0.000
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 97 648 153 592 105 0.0013 177 0.0022 -17.177 0.000
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 481 264 551 194 1096 0.0136 1316 0.0163 -19.442 0.000
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 1 744 14 731 1 1.98e-05 14 0.000278 -13.941 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 17 728 47 698 17 0.000316 49 0.000913 -17.749 0.000
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 368 377 445 300 706 0.0131 1103 0.0205 -46.885 0.000
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 162 583 231 514 238 0.00325 338 0.00462 -18.140 0.000
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 56 689 104 641 61 0.00106 123 0.00214 -20.981 0.000
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 471 274 546 199 1297 0.0129 1861 0.0185 -37.429 0.000
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 23 722 59 686 23 0.000342 60 0.000894 -16.591 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 189 556 264 481 223 0.00332 350 0.00522 -23.636 0.000
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 50 695 99 646 54 0.000938 119 0.00207 -22.359 0.000
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 173 572 251 494 226 0.0028 370 0.00459 -23.783 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 242 503 328 417 304 0.00453 445 0.00663 -23.297 0.000
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 156 589 234 511 173 0.00215 288 0.00358 -21.518 0.000
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 197 548 282 463 243 0.00573 395 0.00932 -33.566 0.000
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 467 278 552 193 1092 0.0135 1762 0.0219 -51.144 0.000
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 53 692 111 634 60 0.00104 136 0.00236 -24.455 0.000
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 216 529 307 438 315 0.00547 486 0.00845 -29.218 0.000
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 390 355 484 261 734 0.00911 1133 0.0141 -37.841 0.000
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 422 323 515 230 849 0.0105 1328 0.0165 -42.008 0.000
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 166 579 253 492 183 0.00227 324 0.00402 -24.873 0.000
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 422 323 517 228 922 0.00915 1462 0.0145 -40.328 0.000
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 12 733 52 693 12 0.000238 54 0.00107 -22.908 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 191 554 298 447 264 0.00393 477 0.00711 -33.968 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 111 634 217 528 128 0.00191 293 0.00437 -33.514 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 154 591 273 472 205 0.00305 424 0.00632 -37.017 0.000
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 0 745 0 745 0 0 0 0 NA 0.000
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 745 0 745 0 10050 0.0997 10484 0.104 -12.955 0.000
E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 0 745 0 745 0 0 0 0 NA 0.000

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HOMER results

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