TF JASPAR ID Class Family Tax Group IC GC Content Target region hits Target region non-hits Background region hits Background region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 194 49 153 90 523 0.042 305 0.025 57.833 10.511 ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 192 51 154 89 465 0.018 421 0.016 6.778 9.221 HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 68 175 39 204 85 0.004 43 0.002 21.215 6.867 TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 130 113 99 144 195 0.011 149 0.009 14.607 5.753 NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 227 16 208 35 790 0.030 614 0.024 22.657 5.624 MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 173 70 144 99 392 0.012 342 0.011 7.636 5.577 STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 173 70 146 97 307 0.013 257 0.011 10.348 5.044 Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 17 226 5 238 18 0.001 5 0.000 22.447 4.923 POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 107 136 80 163 181 0.006 125 0.004 15.014 4.877 NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 210 33 189 54 568 0.022 422 0.016 22.595 4.732 ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 214 29 194 49 519 0.020 529 0.020 -1.450 4.685 HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 58 185 37 206 76 0.003 40 0.002 18.848 4.518 RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 97 146 72 171 133 0.005 93 0.004 13.096 4.504 INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 145 98 120 123 253 0.012 188 0.009 16.442 4.244 POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 84 159 61 182 123 0.006 92 0.005 11.635 4.234 PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 93 150 70 173 127 0.007 90 0.005 15.098 4.063 Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 222 21 206 37 618 0.026 565 0.024 7.417 4.042 Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 122 121 98 145 178 0.008 138 0.006 11.280 4.018 Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 73 170 52 191 81 0.004 61 0.003 9.555 3.972 HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 64 179 44 199 80 0.004 54 0.003 12.731 3.967 MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 231 12 218 25 987 0.038 759 0.029 26.480 3.941 Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 224 19 209 34 645 0.027 589 0.025 7.680 3.892 POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 136 107 113 130 305 0.011 242 0.008 12.151 3.777 Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 168 75 146 97 305 0.012 261 0.010 8.605 3.768 JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 72 171 52 191 96 0.003 64 0.002 11.970 3.734 TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 49 194 32 211 73 0.003 37 0.002 20.472 3.669 Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 225 18 211 32 847 0.033 717 0.028 15.493 3.662 Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 228 15 215 28 695 0.021 624 0.019 8.054 3.608 E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 207 36 190 53 1107 0.047 976 0.041 14.115 3.504 HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 152 91 131 112 280 0.011 239 0.009 8.376 3.416 Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 15 228 6 237 16 0.001 6 0.000 15.749 3.325 PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 44 199 29 214 49 0.003 29 0.002 13.862 3.284 FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 23 220 12 231 27 0.001 13 0.001 14.481 3.244 RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 39 204 25 218 44 0.003 29 0.002 12.427 3.212 CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 63 180 46 197 75 0.003 68 0.003 2.648 3.200 HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 64 179 47 196 87 0.004 54 0.002 14.867 3.175 NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 93 150 74 169 118 0.005 94 0.004 7.800 3.153 IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 24 219 13 230 25 0.001 13 0.001 12.406 3.146 Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 230 13 219 24 772 0.039 717 0.036 7.461 3.146 HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 80 163 62 181 112 0.005 92 0.004 6.887 3.104 Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 162 81 143 100 314 0.011 264 0.009 9.224 3.089 JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 103 140 84 159 164 0.009 117 0.006 16.261 3.066 Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 152 91 133 110 331 0.009 317 0.009 2.043 3.024 GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 150 93 131 112 292 0.011 251 0.010 8.173 3.014 Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 232 11 222 21 909 0.038 814 0.034 11.158 3.012 EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 213 30 199 44 605 0.023 575 0.022 3.936 2.993 NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 218 25 205 38 913 0.035 706 0.027 24.899 2.951 PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 195 48 179 64 708 0.022 659 0.020 5.391 2.938 ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 227 16 216 27 600 0.025 570 0.024 4.151 2.907 NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 47 196 33 210 55 0.002 40 0.002 7.830 2.888 BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 149 94 131 112 285 0.012 224 0.009 13.530 2.826 MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 15 228 7 236 16 0.001 7 0.000 13.116 2.773 Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 36 207 24 219 37 0.002 27 0.002 7.900 2.743 Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 164 79 147 96 290 0.016 258 0.014 7.451 2.730 SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 224 19 213 30 1067 0.045 962 0.041 11.377 2.724 GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 203 40 189 54 597 0.018 552 0.017 5.405 2.694 Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 189 54 174 69 564 0.017 561 0.017 0.304 2.632 FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 135 108 118 125 231 0.010 169 0.007 15.825 2.616 ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 129 114 112 131 210 0.010 168 0.008 11.220 2.614 CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 183 60 168 75 641 0.022 630 0.022 1.266 2.550 POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 54 189 41 202 75 0.004 54 0.003 10.275 2.467 JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 30 213 20 223 32 0.001 24 0.001 5.616 2.416 PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 14 229 7 236 14 0.001 7 0.000 10.853 2.411 SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 197 46 184 59 533 0.025 524 0.024 1.312 2.376 Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 40 203 29 214 45 0.002 34 0.002 6.498 2.336 EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 51 192 39 204 55 0.003 49 0.003 3.394 2.309 MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 15 228 8 235 16 0.001 8 0.000 9.738 2.307 POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 82 161 68 175 138 0.006 106 0.005 10.749 2.294 Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 203 40 191 52 530 0.020 453 0.017 11.479 2.290 LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 125 118 110 133 221 0.009 203 0.008 3.965 2.284 Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 12 231 6 237 13 0.001 7 0.000 9.295 2.167 NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 17 226 10 233 18 0.001 10 0.001 9.068 2.144 PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 24 219 16 227 25 0.001 16 0.001 7.748 2.089 Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 68 175 56 187 96 0.004 76 0.004 7.919 2.070 EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 68 175 56 187 85 0.005 82 0.005 1.245 2.070 OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 69 174 57 186 98 0.004 68 0.003 11.477 2.060 HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 94 149 81 162 145 0.006 130 0.005 4.128 2.053 CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 147 96 134 109 316 0.013 281 0.012 6.913 2.001 Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 20 223 13 230 21 0.001 13 0.001 8.830 1.969 NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 215 28 206 37 667 0.018 540 0.015 14.506 1.944 REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 168 75 156 87 318 0.012 258 0.010 11.819 1.932 NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 166 77 154 89 292 0.011 280 0.011 2.230 1.922 Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 98 145 86 157 134 0.004 128 0.004 1.463 1.885 HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 157 86 145 98 404 0.017 364 0.015 6.950 1.885 NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 22 221 15 228 23 0.002 23 0.002 -0.040 1.881 Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 199 44 189 54 783 0.024 758 0.023 2.533 1.868 GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 211 32 202 41 682 0.021 753 0.023 -7.467 1.865 POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 57 186 47 196 77 0.004 65 0.003 5.123 1.834 Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 195 48 185 58 471 0.020 386 0.016 14.406 1.824 Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 33 210 25 218 35 0.002 28 0.002 5.418 1.810 CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 66 177 56 187 86 0.003 68 0.003 6.871 1.753 ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 26 217 19 224 27 0.001 22 0.001 3.948 1.749 CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 12 231 7 236 14 0.001 7 0.000 9.840 1.744 NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 12 231 7 236 13 0.001 7 0.000 9.295 1.744 JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 155 88 144 99 278 0.012 250 0.011 5.854 1.740 Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 101 142 90 153 145 0.008 117 0.007 10.013 1.734 NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 183 60 173 70 847 0.036 783 0.033 7.636 1.725 Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 106 137 95 148 161 0.009 142 0.008 6.153 1.723 CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 72 171 62 181 85 0.003 92 0.004 -2.350 1.712 HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 137 106 126 117 275 0.011 248 0.010 5.399 1.707 Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 120 123 109 134 197 0.008 185 0.008 2.892 1.705 EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 124 119 113 130 208 0.009 189 0.008 4.555 1.703 Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 178 65 168 75 377 0.013 336 0.012 6.697 1.695 Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 174 69 164 79 348 0.013 358 0.014 -1.735 1.674 KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 210 33 202 41 779 0.033 704 0.030 9.442 1.669 TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 208 35 200 43 831 0.038 795 0.037 4.426 1.642 GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 90 153 80 163 132 0.007 118 0.006 4.793 1.630 NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 45 198 37 206 65 0.003 43 0.002 11.094 1.618 FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 147 96 137 106 248 0.010 228 0.010 4.365 1.591 DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 70 173 61 182 106 0.005 74 0.003 12.865 1.576 Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 120 123 110 133 183 0.007 162 0.006 5.189 1.576 Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 129 114 119 124 301 0.013 304 0.013 -0.626 1.575 HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 225 18 219 24 1066 0.033 1104 0.034 -3.366 1.561 POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 73 170 64 179 108 0.005 95 0.004 4.589 1.561 EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 198 45 190 53 720 0.022 728 0.022 -0.912 1.540 TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 212 31 205 38 904 0.042 848 0.039 6.712 1.524 RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 164 79 155 88 481 0.019 447 0.017 5.070 1.503 Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 58 185 50 193 84 0.002 67 0.002 5.459 1.503 PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 27 216 21 222 28 0.001 24 0.001 2.787 1.497 HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 27 216 21 222 30 0.002 22 0.001 6.109 1.497 HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 27 216 21 222 33 0.002 25 0.001 5.729 1.497 MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 5 238 2 241 6 0.000 2 0.000 10.481 1.492 Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 5 238 2 241 5 0.000 2 0.000 8.118 1.492 Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 96 147 87 156 149 0.007 118 0.005 9.868 1.483 Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 150 93 141 102 335 0.010 298 0.009 6.041 1.472 ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 104 139 95 148 148 0.009 144 0.008 1.250 1.468 OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 121 122 112 131 194 0.007 156 0.006 9.604 1.453 RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 205 38 198 45 449 0.019 427 0.018 3.503 1.449 ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 70 173 62 181 81 0.004 77 0.004 1.669 1.437 GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 77 166 69 174 97 0.003 88 0.003 2.678 1.409 GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 174 69 166 77 433 0.017 472 0.018 -5.786 1.409 Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 12 231 8 235 13 0.001 9 0.000 4.935 1.398 ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 82 161 74 169 109 0.005 101 0.005 2.723 1.393 Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 167 76 159 84 537 0.021 510 0.020 3.756 1.388 HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 165 78 157 86 396 0.015 415 0.016 -3.028 1.382 SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 240 3 237 6 1474 0.040 1160 0.031 24.700 1.379 SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 141 102 133 110 234 0.008 215 0.007 3.856 1.343 MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 112 131 104 139 206 0.012 232 0.013 -6.706 1.342 GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 24 219 19 224 29 0.001 20 0.001 6.928 1.341 Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 186 57 179 64 385 0.015 388 0.015 -0.540 1.330 Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 182 61 175 68 727 0.017 697 0.016 2.749 1.314 POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 74 169 67 176 105 0.004 92 0.004 4.253 1.293 Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 202 41 196 47 522 0.022 499 0.021 3.388 1.280 GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 30 213 25 218 33 0.002 26 0.002 5.788 1.260 HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 157 86 150 93 391 0.015 381 0.015 1.577 1.251 MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 53 190 47 196 67 0.003 51 0.002 7.050 1.247 NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 96 147 89 154 127 0.007 112 0.006 5.462 1.246 OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 54 189 48 195 72 0.003 58 0.002 5.779 1.242 MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 188 55 182 61 389 0.012 427 0.013 -5.286 1.213 E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 236 7 233 10 1389 0.059 1249 0.053 13.401 1.167 NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 10 233 7 236 11 0.001 7 0.000 6.179 1.167 DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 206 37 201 42 938 0.029 907 0.028 2.882 1.166 IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 3 240 1 242 4 0.000 1 0.000 12.603 1.166 STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 224 19 220 23 792 0.034 711 0.030 10.154 1.157 Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 202 41 197 46 524 0.016 523 0.016 0.068 1.145 HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 141 102 135 108 302 0.012 303 0.012 -0.233 1.128 MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 196 47 191 52 665 0.020 659 0.020 0.606 1.120 TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 220 23 216 27 769 0.030 650 0.025 14.876 1.117 Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 234 9 231 12 825 0.029 938 0.032 -11.324 1.114 TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 59 184 54 189 75 0.003 62 0.003 5.687 1.097 LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 13 230 10 233 13 0.001 10 0.001 3.624 1.093 SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 216 27 212 31 1051 0.061 960 0.055 11.604 1.086 TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 65 178 60 183 83 0.003 74 0.003 3.273 1.082 TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 66 177 61 182 81 0.003 71 0.003 3.902 1.079 ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 71 172 66 177 89 0.004 86 0.004 1.035 1.069 BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 35 208 31 212 44 0.002 34 0.002 5.904 1.062 NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 208 35 204 39 876 0.034 818 0.031 6.440 1.043 ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 90 153 85 158 117 0.005 112 0.004 1.457 1.042 PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 111 132 106 137 188 0.006 163 0.005 5.510 1.028 TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 134 109 129 114 275 0.014 237 0.012 8.899 1.027 TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 228 15 225 18 847 0.033 671 0.026 21.693 1.023 Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 18 225 15 228 19 0.001 18 0.001 0.839 1.023 IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 5 238 3 240 5 0.000 3 0.000 4.237 1.016 E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 5 238 3 240 6 0.000 3 0.000 5.910 1.016 Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 5 238 3 240 5 0.000 3 0.000 4.540 1.016 Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 195 48 191 52 774 0.024 757 0.023 1.703 0.999 TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 224 19 221 22 686 0.021 758 0.023 -7.547 0.988 EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 6 237 4 239 8 0.001 5 0.000 5.631 0.979 PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 6 237 4 239 6 0.000 4 0.000 4.055 0.979 POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 25 218 22 221 29 0.002 24 0.001 3.779 0.969 BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 219 24 216 27 1261 0.049 1234 0.048 2.400 0.958 LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 171 72 167 76 457 0.014 410 0.013 6.553 0.958 FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 167 76 163 80 427 0.013 436 0.013 -1.280 0.954 IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 28 215 25 218 29 0.002 28 0.002 0.828 0.953 FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 144 99 140 103 264 0.008 265 0.008 -0.220 0.938 JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 139 104 135 108 227 0.010 214 0.009 2.913 0.937 HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 134 109 130 113 245 0.011 246 0.011 -0.272 0.936 EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 37 206 34 209 42 0.002 40 0.002 1.145 0.919 Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 10 233 8 235 10 0.001 8 0.000 2.775 0.903 SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 234 9 232 11 2044 0.086 1779 0.075 21.550 0.892 SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 56 187 53 190 64 0.003 58 0.003 2.913 0.882 SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 169 74 166 77 457 0.016 447 0.015 1.374 0.862 RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 159 84 156 87 271 0.009 257 0.009 2.584 0.856 HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 145 98 142 101 342 0.013 354 0.014 -2.083 0.851 TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 124 119 121 122 236 0.012 204 0.010 8.068 0.849 TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 222 21 220 23 1522 0.070 1397 0.065 11.870 0.827 OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 208 35 206 37 665 0.020 691 0.021 -2.889 0.800 MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 37 206 35 208 43 0.003 36 0.002 4.916 0.800 ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 59 184 57 186 69 0.003 74 0.003 -2.055 0.782 MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 178 65 176 67 609 0.023 616 0.024 -0.968 0.778 TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 89 154 87 156 116 0.004 121 0.005 -1.481 0.771 Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 194 49 193 50 384 0.015 401 0.015 -2.760 0.693 mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 57 186 56 187 84 0.004 77 0.003 2.610 0.693 Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 228 15 227 16 1408 0.054 1309 0.050 8.785 0.693 NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 243 0 242 1 1869 0.065 1896 0.066 -2.028 0.693 Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 81 162 80 163 108 0.006 94 0.005 5.564 0.693 BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 55 188 54 189 70 0.003 64 0.002 2.335 0.693 NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 51 192 50 193 63 0.002 57 0.002 2.476 0.693 FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 100 143 99 144 161 0.009 175 0.010 -4.166 0.693 ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 7 236 6 237 7 0.000 6 0.000 1.574 0.693 T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 1 242 0 243 1 0.000 0 0.000 NA 0.693 FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 133 110 133 110 237 0.007 234 0.007 0.513 0.623 MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 102 141 102 141 158 0.009 144 0.008 4.490 0.622 FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 154 89 154 89 274 0.012 265 0.011 1.794 0.621 CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 167 76 167 76 374 0.016 343 0.015 5.536 0.618 LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 171 72 171 72 393 0.015 422 0.016 -4.556 0.617 NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 60 183 60 183 71 0.004 81 0.005 -4.352 0.613 PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 192 51 192 51 459 0.016 511 0.018 -7.019 0.608 CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 20 223 20 223 22 0.001 20 0.001 1.631 0.570 MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 224 19 224 19 622 0.019 665 0.020 -4.825 0.567 FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 226 17 226 17 1231 0.033 1191 0.032 3.041 0.561 HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 16 227 16 227 18 0.001 17 0.001 0.830 0.558 TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 100 143 101 142 134 0.005 131 0.005 0.790 0.557 HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 149 94 150 93 246 0.014 239 0.014 1.712 0.555 MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 165 78 166 77 355 0.014 347 0.013 1.314 0.550 ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 169 74 170 73 302 0.012 321 0.012 -3.424 0.548 TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 230 13 230 13 786 0.030 930 0.036 -15.279 0.545 Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 48 195 49 194 67 0.003 64 0.003 1.315 0.528 NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 200 43 201 42 520 0.022 479 0.020 6.213 0.520 Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 9 234 9 234 10 0.001 10 0.001 -0.051 0.520 Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 8 235 8 235 9 0.001 9 0.001 -0.051 0.511 ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 33 210 34 209 46 0.003 44 0.003 1.130 0.505 Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 209 34 210 33 1028 0.032 995 0.031 2.931 0.505 POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 7 236 7 236 7 0.000 7 0.000 -0.055 0.500 TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 7 236 7 236 7 0.000 8 0.001 -1.550 0.500 CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 109 134 111 132 186 0.007 174 0.007 2.842 0.498 KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 94 149 96 147 147 0.008 161 0.009 -4.191 0.495 FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 151 92 153 90 334 0.019 308 0.018 5.729 0.493 BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 214 29 215 28 957 0.029 1019 0.031 -5.653 0.493 TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 237 6 237 6 910 0.035 1022 0.039 -11.381 0.487 Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 62 181 64 179 84 0.004 83 0.004 0.326 0.475 Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 182 61 184 59 370 0.011 365 0.011 0.694 0.472 ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 5 238 5 238 5 0.000 5 0.000 -0.061 0.471 Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 54 189 56 187 82 0.003 85 0.004 -1.120 0.466 SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 17 226 18 225 17 0.001 19 0.001 -1.760 0.451 RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 4 239 4 239 5 0.000 4 0.000 1.931 0.450 Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 4 239 4 239 4 0.000 4 0.000 -0.067 0.450 Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 16 227 17 226 17 0.001 18 0.001 -1.014 0.445 TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 105 138 108 135 150 0.006 158 0.006 -2.060 0.442 FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 137 106 140 103 259 0.011 260 0.011 -0.256 0.442 POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 15 228 16 227 15 0.001 18 0.001 -2.871 0.439 VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 148 95 151 92 342 0.012 398 0.014 -8.530 0.438 FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 156 87 159 84 490 0.021 472 0.020 2.714 0.434 HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 34 209 36 207 42 0.002 50 0.003 -4.425 0.430 OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 208 35 210 33 785 0.024 871 0.027 -8.421 0.427 FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 229 14 230 13 1358 0.037 1290 0.035 5.019 0.425 RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 3 240 3 240 3 0.000 3 0.000 -0.079 0.420 SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 3 240 3 240 3 0.000 3 0.000 -0.077 0.420 DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 66 177 69 174 94 0.004 93 0.004 0.305 0.420 SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 12 231 13 230 12 0.001 13 0.001 -1.120 0.417 ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 185 58 188 55 381 0.016 404 0.017 -3.884 0.406 Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 10 233 11 232 11 0.001 11 0.001 -0.050 0.398 Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 126 117 130 113 282 0.013 312 0.014 -5.978 0.393 TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 127 116 131 112 249 0.012 223 0.011 6.261 0.393 CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 133 110 137 106 266 0.010 233 0.009 6.818 0.392 VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 135 108 139 104 333 0.010 356 0.011 -3.515 0.391 FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 139 104 143 100 228 0.010 222 0.009 1.294 0.390 STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 44 199 47 196 47 0.003 54 0.003 -3.732 0.387 Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 196 47 199 44 557 0.017 617 0.019 -6.955 0.387 RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 21 222 23 220 22 0.001 23 0.001 -0.822 0.383 LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 156 87 160 83 495 0.017 491 0.017 0.489 0.382 ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 157 86 161 82 437 0.013 452 0.014 -2.062 0.381 PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 169 74 173 70 583 0.018 601 0.019 -2.155 0.371 CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 130 113 135 108 255 0.010 220 0.008 7.445 0.346 HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 96 147 101 142 170 0.008 141 0.007 8.442 0.342 Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 6 237 7 236 6 0.000 7 0.000 -1.472 0.340 Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 6 237 7 236 6 0.000 8 0.001 -2.967 0.340 E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 26 217 29 214 26 0.001 31 0.001 -3.152 0.333 TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 228 15 230 13 1543 0.065 1531 0.065 0.948 0.328 GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 169 74 174 69 332 0.013 323 0.012 1.542 0.322 XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 23 220 26 217 24 0.001 27 0.001 -2.201 0.320 GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 5 238 6 237 5 0.000 6 0.000 -1.589 0.318 SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 5 238 6 237 5 0.000 6 0.000 -1.641 0.318 EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 63 180 68 175 78 0.004 91 0.005 -4.963 0.315 Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 180 63 185 58 580 0.018 585 0.018 -0.648 0.307 TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 220 23 223 20 720 0.022 664 0.020 6.147 0.303 FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 137 106 143 100 370 0.017 345 0.016 4.642 0.301 JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 98 145 104 139 142 0.008 153 0.009 -3.504 0.301 Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 141 102 147 96 221 0.009 267 0.011 -9.436 0.300 FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 231 12 233 10 1672 0.045 1643 0.044 1.849 0.297 ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 191 52 196 47 394 0.015 430 0.017 -5.591 0.287 MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 242 1 242 1 2747 0.063 2425 0.056 16.383 0.287 E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 1 242 1 242 1 0.000 1 0.000 -0.136 0.287 BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 1 242 1 242 1 0.000 1 0.000 -0.136 0.287 NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 1 242 1 242 1 0.000 1 0.000 -0.124 0.287 TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 1 242 1 242 1 0.000 1 0.000 -0.121 0.287 Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 162 81 168 75 285 0.012 353 0.015 -12.145 0.285 Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 162 81 168 75 243 0.009 313 0.012 -12.634 0.285 GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 45 198 50 193 48 0.003 61 0.003 -6.275 0.283 Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 41 202 46 197 46 0.002 63 0.003 -7.770 0.273 EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 176 67 182 61 542 0.021 566 0.022 -3.287 0.269 Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 124 119 131 112 177 0.004 220 0.005 -7.158 0.266 Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 200 43 205 38 935 0.025 930 0.025 0.372 0.265 ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 180 63 186 57 361 0.014 361 0.014 -0.053 0.262 NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 3 240 4 239 3 0.000 4 0.000 -1.943 0.255 TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 3 240 4 239 3 0.000 4 0.000 -1.809 0.255 VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 154 89 161 82 463 0.014 458 0.014 0.612 0.253 PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 7 236 9 234 7 0.000 9 0.000 -2.365 0.253 FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 204 39 209 34 682 0.018 685 0.018 -0.365 0.253 SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 20 223 24 219 21 0.001 25 0.001 -2.926 0.242 TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 169 74 176 67 303 0.009 342 0.011 -6.043 0.238 FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 174 69 181 62 459 0.012 457 0.012 0.198 0.232 PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 11 232 14 229 11 0.001 14 0.001 -2.826 0.231 FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 210 33 215 28 858 0.023 828 0.022 2.725 0.230 FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 101 142 109 134 197 0.008 191 0.008 1.400 0.229 ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 27 216 32 211 29 0.002 36 0.002 -4.560 0.226 NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 198 45 204 39 445 0.017 469 0.018 -3.594 0.224 Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 56 187 63 180 70 0.005 85 0.006 -6.766 0.222 HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 17 226 21 222 17 0.001 22 0.001 -3.736 0.222 ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 214 29 219 24 541 0.021 689 0.027 -18.133 0.212 MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 236 7 238 5 921 0.028 1107 0.034 -16.159 0.212 PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 34 209 40 203 43 0.002 57 0.002 -5.907 0.209 ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 2 241 3 240 2 0.000 3 0.000 -2.455 0.206 MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 2 241 3 240 2 0.000 3 0.000 -2.714 0.206 KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 240 3 241 2 2710 0.104 2464 0.095 16.340 0.206 TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 121 122 130 113 185 0.008 207 0.009 -5.138 0.201 Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 64 179 72 171 87 0.005 101 0.005 -5.266 0.200 RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 132 111 141 102 193 0.007 207 0.008 -3.133 0.199 ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 31 212 37 206 32 0.002 39 0.002 -4.083 0.199 Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 96 147 105 138 128 0.004 167 0.005 -8.596 0.197 Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 86 157 95 148 114 0.004 132 0.005 -5.006 0.191 KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 4 239 6 237 5 0.000 7 0.000 -3.260 0.186 MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 38 205 45 198 43 0.002 50 0.002 -3.324 0.183 EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 227 16 231 12 1520 0.082 1396 0.075 12.797 0.181 BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 211 32 217 26 986 0.030 949 0.029 3.375 0.179 RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 7 236 10 233 8 0.000 10 0.001 -2.417 0.177 Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 7 236 10 233 9 0.001 10 0.001 -1.352 0.177 TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 118 125 128 115 193 0.010 197 0.011 -1.120 0.173 JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 102 141 112 131 135 0.007 171 0.009 -10.011 0.171 Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 147 96 157 86 242 0.007 271 0.008 -5.047 0.164 TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 152 91 162 81 242 0.007 310 0.010 -11.019 0.161 PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 78 165 88 155 127 0.005 162 0.007 -9.192 0.158 GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 156 87 166 77 312 0.012 395 0.015 -13.358 0.157 ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 114 129 125 118 169 0.007 194 0.007 -5.739 0.149 ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 95 148 106 137 136 0.007 146 0.007 -3.038 0.144 Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 144 99 155 88 267 0.011 283 0.012 -3.223 0.141 ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 88 155 99 144 123 0.007 130 0.008 -2.430 0.141 Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 5 238 8 235 5 0.000 8 0.001 -4.424 0.139 Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 84 159 95 148 99 0.005 129 0.006 -9.594 0.139 Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 202 41 210 33 421 0.018 558 0.024 -19.525 0.137 RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 12 231 17 226 13 0.001 17 0.001 -3.674 0.134 MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 1 242 2 241 1 0.000 2 0.000 -2.833 0.133 GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 1 242 2 241 1 0.000 2 0.000 -2.920 0.133 POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 23 220 30 213 30 0.002 37 0.002 -4.347 0.130 Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 23 220 30 213 26 0.001 33 0.002 -4.263 0.130 FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 164 79 175 68 295 0.011 327 0.013 -5.681 0.126 RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 4 239 7 236 6 0.000 7 0.000 -1.567 0.117 Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 10 233 15 228 10 0.001 16 0.001 -6.228 0.115 Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 113 130 126 117 156 0.005 193 0.006 -7.595 0.108 CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 41 202 51 192 47 0.003 56 0.003 -4.703 0.107 TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 12 231 18 225 12 0.001 19 0.001 -5.608 0.098 Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 22 221 30 213 25 0.001 34 0.002 -5.818 0.098 Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 80 163 93 150 141 0.006 172 0.007 -7.909 0.097 NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 186 57 197 46 715 0.022 656 0.020 6.519 0.096 EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 27 216 36 207 29 0.001 48 0.002 -9.546 0.092 Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 3 240 6 237 3 0.000 6 0.000 -4.956 0.092 POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 101 142 115 128 176 0.007 179 0.007 -0.755 0.089 SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 69 174 82 161 85 0.004 99 0.005 -5.125 0.089 MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 68 175 81 162 87 0.004 127 0.006 -12.369 0.088 Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 222 21 229 14 796 0.018 932 0.022 -11.090 0.083 ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 152 91 166 77 272 0.010 312 0.012 -7.253 0.079 MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 45 198 57 186 61 0.002 66 0.003 -1.987 0.077 PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 22 221 31 212 27 0.001 40 0.002 -6.542 0.075 SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 28 215 38 205 29 0.001 42 0.002 -6.386 0.075 HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 93 150 108 135 119 0.005 164 0.006 -11.186 0.073 Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 31 212 42 201 39 0.002 50 0.003 -6.269 0.066 PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 38 205 50 193 52 0.002 68 0.003 -6.481 0.065 Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 1 242 3 240 1 0.000 3 0.000 -4.835 0.064 ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 158 85 173 70 298 0.011 328 0.013 -5.321 0.061 ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 23 220 33 210 24 0.001 44 0.002 -10.490 0.061 SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 53 190 67 176 76 0.005 113 0.007 -14.443 0.059 Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 32 211 44 199 32 0.001 54 0.002 -9.512 0.053 RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 73 170 89 154 87 0.003 111 0.004 -7.256 0.052 ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 15 228 24 219 16 0.001 29 0.001 -8.747 0.048 Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 4 239 9 234 4 0.000 9 0.001 -6.921 0.045 FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 166 77 182 61 314 0.012 351 0.014 -6.338 0.044 RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 8 235 15 228 8 0.001 15 0.001 -7.496 0.044 ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 197 46 210 33 576 0.018 693 0.021 -12.765 0.043 MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 55 188 71 172 70 0.003 103 0.005 -11.327 0.040 Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 5 238 11 232 5 0.000 11 0.001 -7.506 0.037 Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 165 78 182 61 294 0.011 356 0.014 -10.512 0.036 Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 12 231 21 222 12 0.001 22 0.001 -8.300 0.036 CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 19 224 30 213 19 0.001 33 0.002 -10.671 0.035 RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 9 234 17 226 11 0.001 18 0.001 -6.643 0.034 YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 58 185 75 168 63 0.003 89 0.004 -9.194 0.034 ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 89 154 108 135 116 0.004 154 0.006 -9.751 0.033 Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 38 205 53 190 52 0.003 63 0.004 -5.763 0.032 ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 82 161 101 142 106 0.004 134 0.005 -7.707 0.031 NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 183 60 199 44 406 0.014 447 0.015 -5.917 0.030 Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 145 98 164 79 243 0.009 279 0.011 -6.899 0.030 Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 6 237 13 230 6 0.000 14 0.001 -8.860 0.030 SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 77 166 96 147 95 0.004 122 0.005 -8.166 0.029 Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 59 184 77 166 69 0.003 102 0.005 -11.382 0.028 TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 206 37 219 24 749 0.032 792 0.034 -5.229 0.028 USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 131 112 151 92 192 0.008 276 0.012 -16.912 0.027 BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 34 209 49 194 37 0.001 59 0.002 -9.103 0.027 NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 56 187 74 169 64 0.003 96 0.005 -11.840 0.026 FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 207 36 220 23 495 0.019 630 0.024 -17.278 0.026 MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 139 104 159 84 200 0.008 286 0.011 -16.214 0.025 DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 53 190 71 172 66 0.003 100 0.005 -12.326 0.024 HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 104 139 125 118 143 0.006 180 0.007 -8.792 0.023 GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 29 214 44 199 32 0.001 46 0.002 -7.194 0.021 ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 23 220 37 206 24 0.001 46 0.002 -12.186 0.019 ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 2 241 7 236 2 0.000 7 0.000 -6.872 0.019 CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 122 121 144 99 167 0.005 225 0.007 -11.014 0.018 NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 189 54 206 37 408 0.013 507 0.016 -12.585 0.018 Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 35 208 52 191 38 0.003 62 0.005 -13.351 0.017 Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 4 239 11 232 4 0.000 11 0.001 -8.222 0.016 Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 25 218 40 203 25 0.001 45 0.002 -9.933 0.016 Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 106 137 129 114 174 0.008 188 0.009 -3.597 0.015 Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 61 182 82 161 83 0.005 119 0.007 -12.864 0.014 TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 214 29 227 16 923 0.039 1001 0.042 -8.437 0.014 ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 19 224 33 210 24 0.001 39 0.002 -9.032 0.014 PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 69 174 91 152 90 0.007 124 0.009 -13.411 0.013 MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 134 109 157 86 203 0.008 277 0.011 -14.179 0.013 NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 222 21 233 10 653 0.025 761 0.029 -12.633 0.012 ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 18 225 32 211 22 0.001 41 0.002 -11.149 0.012 Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 79 164 102 141 101 0.003 142 0.004 -9.789 0.012 Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 78 165 101 142 95 0.004 120 0.005 -7.626 0.012 DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 117 126 141 102 218 0.009 325 0.014 -19.868 0.012 RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 17 226 31 212 20 0.001 35 0.002 -10.188 0.011 HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 7 236 17 226 7 0.000 18 0.001 -9.027 0.010 FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 205 38 221 22 761 0.020 864 0.023 -9.442 0.009 ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 32 211 51 192 33 0.001 62 0.003 -12.265 0.008 RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 1 242 6 237 1 0.000 6 0.000 -8.472 0.008 SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 141 102 166 77 209 0.008 316 0.012 -19.195 0.007 TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 113 130 139 104 145 0.006 233 0.009 -18.353 0.007 ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 30 213 49 194 32 0.001 60 0.003 -12.573 0.007 Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 160 83 184 59 277 0.009 389 0.012 -16.203 0.006 Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 89 154 116 127 106 0.004 176 0.007 -16.779 0.005 MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 34 209 55 188 39 0.002 66 0.003 -11.565 0.005 GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 109 134 137 106 170 0.007 209 0.009 -9.030 0.004 Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 163 80 188 55 310 0.011 373 0.013 -9.898 0.004 Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 40 203 63 180 40 0.002 81 0.003 -14.462 0.004 TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 229 14 239 4 678 0.021 792 0.024 -11.662 0.003 SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 98 145 128 115 127 0.005 190 0.007 -14.545 0.002 CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 54 189 81 162 61 0.002 100 0.004 -12.391 0.002 USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 135 108 165 78 196 0.008 298 0.013 -19.766 0.002 Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 43 200 69 174 48 0.003 81 0.005 -14.269 0.002 Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 119 124 150 93 185 0.006 237 0.008 -10.217 0.002 BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 89 154 120 123 113 0.004 182 0.007 -16.268 0.002 TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 130 113 162 81 182 0.007 284 0.011 -19.288 0.001 Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 170 73 198 45 485 0.026 584 0.031 -15.643 0.001 ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 189 54 214 29 422 0.015 551 0.019 -16.700 0.001 TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 175 68 203 40 303 0.012 461 0.018 -23.529 0.001 SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 39 204 68 175 40 0.002 90 0.003 -16.728 0.000 MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 34 209 63 180 35 0.001 78 0.003 -15.453 0.000 NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 95 148 137 106 127 0.006 201 0.010 -18.956 0.000 YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 65 178 108 135 79 0.004 153 0.007 -20.834 0.000 MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 17 226 47 196 19 0.001 62 0.002 -17.322 0.000 ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 243 0 243 0 2103 0.049 2256 0.052 -8.195 0.000 Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 0 243 1 242 0 0.000 1 0.000 -4.127 0.000 E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 0 243 3 240 0 0.000 3 0.000 -7.420 0.000 Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 0 243 2 241 0 0.000 2 0.000 -5.919 0.000 BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 0 243 0 243 0 0.000 0 0.000 NA 0.000 TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 0 243 0 243 0 0.000 0 0.000 NA 0.000 HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 243 0 243 0 1980 0.069 2051 0.071 -4.987 0.000 SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 0 243 1 242 0 0.000 1 0.000 -4.127 0.000 IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 0 243 1 242 0 0.000 1 0.000 -4.004 0.000 PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 0 243 0 243 0 0.000 0 0.000 NA 0.000 Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 0 243 1 242 0 0.000 1 0.000 -4.004 0.000 TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 0 243 2 241 0 0.000 2 0.000 -6.086 0.000 RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 243 0 243 0 3161 0.097 3181 0.098 -1.184 0.000 E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 0 243 0 243 0 0.000 0 0.000 NA 0.000 SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 241 2 243 0 1175 0.041 1434 0.050 -21.131 0.000 RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 0 243 1 242 0 0.000 1 0.000 -4.362 0.000 SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 0 243 0 243 0 0.000 0 0.000 NA 0.000 REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 0 243 0 243 0 0.000 0 0.000 NA 0.000