Human Analysis


Summary

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Job ID: FF:11797-124C6
Number of target experiments: 1
Number of target CAGE peaks: 954
Number of target CAGE peak regions: 639
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 639
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:11797-124C6 CD4+CD25+CD45RA- memory regulatory T cells, donor2


Results

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Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 578 61 443 196 1334 0.0192 821 0.0118 56.864 48.703
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 512 127 354 285 1019 0.0147 612 0.00883 52.175 48.164
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 556 83 413 226 1384 0.0219 856 0.0136 60.168 47.485
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 595 44 473 166 1659 0.0239 1080 0.0156 56.053 47.113
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 554 85 414 225 1193 0.0172 733 0.0106 53.928 45.451
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 539 100 396 243 1152 0.0166 684 0.00987 56.782 44.245
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 540 99 398 241 1136 0.0164 685 0.00988 54.678 43.896
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 530 109 390 249 1103 0.0159 673 0.00971 52.588 41.338
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 405 234 249 390 644 0.00928 374 0.00539 44.201 41.089
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 560 79 438 201 1412 0.0204 926 0.0134 50.752 37.414
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 340 299 196 443 493 0.00711 251 0.00362 48.328 36.201
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 443 196 317 322 852 0.0135 553 0.00877 42.279 28.459
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 274 365 154 485 374 0.00593 186 0.00295 45.727 28.012
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 321 318 208 431 484 0.00698 293 0.00423 35.300 23.144
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 601 38 535 104 1960 0.0311 1377 0.0218 52.574 20.007
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 317 322 225 414 455 0.00656 295 0.00425 29.462 15.908
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 129 510 67 572 145 0.00251 82 0.00142 24.070 13.886
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 143 496 79 560 160 0.00277 88 0.00152 26.560 13.441
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 257 382 180 459 322 0.00696 233 0.00504 22.580 12.545
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 562 77 503 136 1431 0.0227 1162 0.0184 26.321 12.014
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 547 92 487 152 2206 0.0382 1827 0.0316 31.091 11.292
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 537 102 478 161 2024 0.035 1684 0.0291 29.011 10.469
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 504 135 440 199 2298 0.0364 2079 0.033 16.080 10.443
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 96 543 50 589 102 0.00191 58 0.00109 20.797 10.293
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 157 482 101 538 185 0.0032 119 0.00206 20.932 9.712
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 82 557 41 598 90 0.00182 42 0.000848 27.677 9.628
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 262 377 196 443 333 0.00528 268 0.00425 13.144 9.519
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 509 130 450 189 1781 0.0282 1618 0.0257 13.510 9.359
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 73 566 35 604 89 0.00231 51 0.00132 22.544 9.347
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 449 190 385 254 1027 0.0311 796 0.0241 37.870 9.157
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 436 203 374 265 822 0.0166 694 0.014 18.226 8.537
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 590 49 550 89 2051 0.0384 1626 0.0305 38.471 8.498
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 425 214 365 274 714 0.0103 585 0.00844 16.870 7.995
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 202 437 148 491 263 0.00569 187 0.00405 21.513 7.738
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 265 374 208 431 345 0.00497 253 0.00365 18.271 7.447
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 575 64 535 104 3597 0.0622 3102 0.0537 31.493 7.423
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 174 465 125 514 242 0.00593 216 0.0053 7.259 7.202
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 602 37 570 69 2399 0.038 1966 0.0312 32.784 7.156
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 573 66 535 104 1740 0.0276 1445 0.0229 25.934 6.797
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 420 219 366 273 730 0.0105 599 0.00864 16.931 6.769
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 173 466 127 512 214 0.00432 147 0.00297 20.656 6.522
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 214 425 166 473 283 0.00408 202 0.00291 17.999 6.216
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 631 8 614 25 6323 0.0911 5733 0.0827 25.537 6.199
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 552 87 513 126 2464 0.0391 2233 0.0354 16.385 6.150
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 632 7 616 23 4115 0.0415 3132 0.0316 47.097 6.048
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 104 535 69 570 121 0.00244 80 0.00162 17.120 5.929
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 317 322 267 372 577 0.0108 487 0.00913 14.703 5.824
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 34 605 15 624 36 0.000726 15 0.000303 20.239 5.508
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 431 208 385 254 1835 0.0291 1599 0.0254 19.720 5.431
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 566 73 533 106 1521 0.0241 1380 0.0219 12.631 5.323
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 208 431 167 472 258 0.00558 221 0.00478 9.609 4.966
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 564 75 533 106 1691 0.0244 1618 0.0233 5.709 4.833
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 450 189 410 229 959 0.0152 893 0.0142 7.298 4.605
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 604 35 582 57 3425 0.0494 3813 0.055 -20.579 4.483
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 578 61 551 88 1756 0.0278 1621 0.0257 11.162 4.457
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 259 380 219 420 365 0.00789 308 0.00666 12.560 4.418
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 593 46 569 70 2457 0.0354 2280 0.0329 11.802 4.391
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 542 97 511 128 1481 0.0213 1360 0.0196 10.386 4.290
*BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 6 633 0 639 6 0.000121 0 0 NA 4.171
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 510 129 477 162 1381 0.0219 1252 0.0199 12.120 4.114
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 597 42 575 64 2268 0.0327 1800 0.026 35.231 4.112
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 100 539 73 566 113 0.00228 81 0.00164 13.271 4.096
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 606 33 586 53 2300 0.0332 2174 0.0314 8.569 4.094
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 473 166 438 201 1232 0.0213 1207 0.0209 2.427 4.032
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 439 200 403 236 758 0.0164 710 0.0154 6.949 3.941
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 177 462 144 495 216 0.00436 169 0.00341 13.501 3.939
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 249 390 214 425 345 0.00746 275 0.00595 16.337 3.734
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 421 218 386 253 984 0.0142 1004 0.0145 -2.087 3.717
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 623 16 609 30 2819 0.0406 2719 0.0392 6.061 3.693
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 84 555 61 578 91 0.00157 61 0.00106 13.270 3.649
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 475 164 443 196 883 0.0115 793 0.0103 9.567 3.616
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 95 544 71 568 111 0.00224 84 0.0017 10.989 3.586
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 305 334 270 369 532 0.00997 459 0.00861 12.272 3.578
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 517 122 488 151 1133 0.0163 1063 0.0153 6.760 3.578
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 225 414 192 447 302 0.00522 254 0.0044 10.404 3.572
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 171 468 141 498 223 0.00482 184 0.00398 11.106 3.526
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 157 482 128 511 186 0.00456 165 0.00405 6.704 3.510
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 519 120 491 148 2360 0.051 2096 0.0453 22.717 3.451
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 576 63 554 85 3414 0.0689 3134 0.0633 19.172 3.410
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 514 125 486 153 1209 0.0174 1090 0.0157 11.404 3.396
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 165 474 137 502 194 0.00308 166 0.00263 7.172 3.279
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 400 239 368 271 762 0.011 653 0.00942 13.483 3.263
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 114 525 90 549 135 0.00292 105 0.00227 11.307 3.234
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 198 441 169 470 273 0.0059 250 0.00541 5.595 3.178
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 601 38 584 55 1936 0.0223 1758 0.0203 12.037 3.165
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 409 230 378 261 833 0.012 742 0.0107 10.550 3.165
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 16 623 7 632 16 0.000346 7 0.000151 13.115 3.099
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 82 557 62 577 92 0.00159 67 0.00116 10.545 3.073
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 120 519 97 542 135 0.00195 117 0.00169 5.226 2.985
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 306 333 276 363 480 0.0104 378 0.00818 20.334 2.963
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 611 28 597 42 4711 0.0747 4174 0.0662 28.357 2.906
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 576 63 557 82 1890 0.0218 2141 0.0247 -15.629 2.881
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 281 358 252 387 483 0.00905 410 0.00769 12.985 2.881
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 243 396 215 424 354 0.00765 361 0.00781 -1.492 2.854
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 581 58 563 76 1739 0.0251 1764 0.0254 -2.006 2.810
*E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 4 635 0 639 4 0.000104 0 0 NA 2.777
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 60 579 44 595 67 0.00116 44 0.000762 11.973 2.776
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 287 352 259 380 395 0.00455 371 0.00428 3.482 2.758
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 339 300 311 328 533 0.00922 478 0.00827 8.686 2.727
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 24 615 14 625 24 0.000415 14 0.000242 9.208 2.679
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 464 175 439 200 1024 0.0118 1094 0.0126 -6.095 2.657
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 316 323 289 350 502 0.00579 445 0.00513 7.608 2.623
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 596 43 581 58 2174 0.0345 2056 0.0326 8.659 2.615
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 121 518 101 538 131 0.00264 110 0.00222 7.457 2.522
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 249 390 224 415 422 0.00852 392 0.00792 5.630 2.499
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 403 236 378 261 750 0.0119 751 0.0119 -0.193 2.474
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 494 145 473 166 1079 0.0124 1090 0.0126 -1.021 2.342
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 38 601 27 612 40 0.00098 28 0.000687 9.312 2.289
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 377 262 354 285 676 0.0136 585 0.0118 14.086 2.237
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 166 473 146 493 203 0.0041 212 0.00428 -2.365 2.226
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 638 1 634 5 3805 0.0494 3832 0.0497 -1.481 2.218
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 602 37 590 49 3028 0.048 2846 0.0452 11.443 2.211
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 50 589 38 601 56 0.00113 39 0.000788 10.148 2.189
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 527 112 509 130 1263 0.0146 1162 0.0134 8.359 2.186
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 354 285 332 307 646 0.0102 543 0.00862 14.656 2.125
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 588 51 575 64 2733 0.0276 2734 0.0276 -0.155 2.117
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 306 333 285 354 452 0.00782 413 0.00715 6.612 2.033
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 9 630 4 635 9 0.000233 5 0.00013 7.528 2.024
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 419 220 399 240 873 0.0138 892 0.0142 -2.201 2.009
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 103 536 88 551 117 0.0027 109 0.00252 3.026 1.995
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 402 237 382 257 648 0.00934 685 0.00988 -4.557 1.984
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 287 352 267 372 393 0.00453 402 0.00464 -1.322 1.954
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 597 42 586 53 2021 0.0233 2175 0.0251 -9.555 1.944
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 43 596 33 606 43 0.00093 33 0.000714 6.704 1.941
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 584 55 572 67 2106 0.0304 1898 0.0274 15.200 1.914
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 45 594 35 604 45 0.000778 41 0.00071 2.126 1.902
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 397 242 378 261 730 0.0116 708 0.0112 2.687 1.888
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 509 130 493 146 1408 0.0223 1177 0.0187 22.448 1.871
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 439 200 421 218 910 0.0118 906 0.0118 0.330 1.862
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 319 320 300 339 520 0.00899 475 0.00822 7.119 1.853
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 629 10 623 16 2922 0.0337 2927 0.0338 -0.381 1.827
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 409 230 391 248 710 0.00819 659 0.0076 5.580 1.815
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 203 436 186 453 260 0.003 230 0.00265 5.558 1.800
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 557 82 544 95 2488 0.0287 2859 0.033 -20.063 1.798
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 586 53 575 64 1662 0.024 1685 0.0243 -1.891 1.796
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 556 83 543 96 1613 0.0186 1960 0.0226 -22.511 1.791
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 448 191 431 208 757 0.0109 737 0.0106 2.274 1.789
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 485 154 469 170 942 0.0136 1047 0.0151 -10.415 1.787
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 441 198 424 215 777 0.0112 848 0.0122 -7.827 1.776
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 426 213 409 230 794 0.0126 737 0.0117 6.932 1.752
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 424 215 407 232 769 0.0111 767 0.0111 0.161 1.749
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 528 111 514 125 1820 0.021 1994 0.023 -11.242 1.747
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 18 621 12 627 19 0.000438 14 0.000323 5.300 1.726
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 161 478 146 493 197 0.00341 178 0.00308 4.895 1.717
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 26 613 19 620 30 0.000778 19 0.000493 10.665 1.707
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 26 613 19 620 26 0.00045 23 0.000398 2.125 1.707
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 36 603 28 611 36 0.000623 33 0.000571 1.770 1.689
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 20 619 14 625 21 0.000424 14 0.000283 6.953 1.647
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 8 631 4 635 8 0.000161 4 8.08e-05 7.409 1.647
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 8 631 4 635 8 0.000208 4 0.000104 8.418 1.647
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 406 233 390 249 827 0.00954 835 0.00963 -0.852 1.643
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 161 478 147 492 184 0.00345 181 0.00339 0.760 1.621
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 615 24 608 31 2424 0.0349 2430 0.035 -0.509 1.589
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 15 624 10 629 21 0.000545 10 0.00026 14.708 1.561
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 15 624 10 629 15 0.000389 11 0.000286 5.070 1.561
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 48 591 40 599 51 0.00103 42 0.000848 5.158 1.515
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 597 42 589 50 3554 0.0359 3973 0.0401 -18.070 1.494
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 181 458 168 471 227 0.00294 212 0.00275 3.051 1.489
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 400 239 386 253 643 0.00927 693 0.01 -6.100 1.481
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 91 548 81 558 101 0.00175 94 0.00163 2.463 1.468
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 97 542 87 552 118 0.00357 95 0.00288 10.782 1.441
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 486 153 474 165 1051 0.0136 1116 0.0145 -5.955 1.434
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 510 129 499 140 1452 0.0146 1480 0.0149 -2.018 1.401
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 565 74 556 83 2172 0.0219 2309 0.0233 -7.726 1.395
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 601 38 594 45 2973 0.0343 3483 0.0402 -25.065 1.394
*E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 2 637 0 639 2 4.61e-05 0 0 NA 1.387
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 639 0 637 2 5312 0.0689 5296 0.0687 0.519 1.387
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 581 58 573 66 3319 0.0478 3052 0.044 15.495 1.370
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 23 616 18 621 23 0.000564 18 0.000441 4.817 1.336
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 132 507 122 517 169 0.00365 171 0.0037 -0.639 1.331
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 24 615 19 620 24 0.000588 20 0.00049 3.647 1.318
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 289 350 277 362 400 0.00865 399 0.00863 0.132 1.317
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 55 584 48 591 58 0.00125 49 0.00106 4.943 1.314
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 542 97 533 106 1840 0.0212 1978 0.0228 -8.970 1.308
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 427 212 416 223 942 0.0109 944 0.0109 -0.253 1.282
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 61 578 54 585 68 0.00118 56 0.000969 5.518 1.277
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 559 80 551 88 2743 0.0316 3065 0.0354 -16.861 1.269
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 16 623 12 627 16 0.000346 12 0.00026 4.424 1.260
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 97 542 89 550 111 0.00224 100 0.00202 4.078 1.240
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 71 568 64 575 74 0.00107 69 0.000995 1.866 1.229
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 155 484 146 493 177 0.00255 168 0.00242 2.156 1.207
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 240 399 230 409 401 0.00636 403 0.00639 -0.387 1.201
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 81 558 74 565 89 0.00154 77 0.00133 4.700 1.192
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 82 557 75 564 86 0.00161 79 0.00148 2.802 1.189
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 344 295 334 305 577 0.00998 654 0.0113 -10.555 1.181
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 326 313 316 323 473 0.0075 500 0.00793 -4.079 1.180
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 468 171 459 180 1410 0.0183 1518 0.0197 -8.485 1.177
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 638 1 636 3 5420 0.0703 5384 0.0699 1.360 1.164
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 94 545 87 552 102 0.00162 101 0.0016 0.291 1.155
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 94 545 87 552 105 0.00272 99 0.00257 2.519 1.155
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 435 204 426 213 1015 0.0219 1067 0.0231 -6.331 1.150
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 427 212 418 221 943 0.0136 982 0.0142 -4.039 1.145
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 23 616 19 620 24 0.000553 22 0.000508 1.665 1.142
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 167 472 159 480 201 0.00492 195 0.00478 1.725 1.119
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 321 318 312 327 472 0.00748 469 0.00744 0.402 1.117
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 26 613 22 617 27 0.000545 23 0.000464 3.080 1.110
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 617 22 613 26 4815 0.0486 5358 0.0541 -20.318 1.110
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 466 173 458 181 1042 0.015 1034 0.0149 0.714 1.106
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 455 184 447 192 1375 0.0178 1538 0.02 -12.680 1.097
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 13 626 10 629 14 0.000343 10 0.000245 5.166 1.086
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 306 333 298 341 462 0.00799 506 0.00876 -6.866 1.057
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 475 164 468 171 1373 0.0158 1521 0.0176 -10.909 1.046
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 36 603 32 607 36 0.000778 32 0.000692 2.700 1.037
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 37 602 33 606 37 0.000747 34 0.000687 1.886 1.032
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 39 600 35 604 43 0.000744 38 0.000658 2.771 1.022
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 569 70 564 75 2251 0.026 2736 0.0316 -26.751 1.016
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 5 634 3 636 5 0.000151 3 9.09e-05 5.221 1.014
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 602 37 598 41 2021 0.0291 2136 0.0308 -8.100 1.013
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 555 84 550 89 1735 0.0175 1623 0.0164 7.332 0.989
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 163 476 157 482 208 0.0021 188 0.0019 3.822 0.985
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 6 633 4 635 6 0.000112 4 7.5e-05 3.530 0.977
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 545 94 540 99 1446 0.0208 1371 0.0198 6.378 0.975
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 58 581 54 585 62 0.00116 57 0.00107 2.350 0.959
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 117 522 112 527 149 0.00301 132 0.00267 5.499 0.954
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 580 59 576 63 2641 0.0305 3249 0.0375 -30.862 0.948
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 520 119 515 124 1410 0.0163 1419 0.0164 -0.763 0.947
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 507 132 502 137 1515 0.0175 1708 0.0197 -13.425 0.937
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 452 187 447 192 1169 0.0135 1248 0.0144 -6.446 0.908
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 10 629 8 631 10 0.000245 8 0.000196 2.863 0.900
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 43 596 40 599 49 0.00113 44 0.00102 2.978 0.891
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 356 283 351 288 563 0.0073 623 0.00809 -7.299 0.889
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 528 111 524 115 1958 0.0226 2194 0.0253 -14.529 0.884
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 75 564 72 567 85 0.00196 80 0.00185 2.198 0.843
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 76 563 73 566 79 0.00194 78 0.00191 0.427 0.842
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 287 352 283 356 402 0.00579 412 0.00594 -1.616 0.837
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 295 344 291 348 493 0.00568 490 0.00565 0.331 0.837
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 36 603 34 605 37 0.000907 34 0.000834 2.083 0.796
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 208 431 205 434 262 0.00378 281 0.00405 -3.638 0.793
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 421 218 418 221 1085 0.0188 1293 0.0224 -20.353 0.792
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 430 209 428 211 744 0.0118 838 0.0133 -10.913 0.742
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 240 399 238 401 322 0.00603 305 0.00572 3.465 0.740
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 250 389 248 391 365 0.00526 348 0.00502 2.837 0.740
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 262 377 260 379 391 0.00451 371 0.00428 2.894 0.740
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 3 636 2 637 3 6.05e-05 2 4.04e-05 2.547 0.693
SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 2 637 1 638 2 4.61e-05 1 2.31e-05 3.871 0.693
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 637 2 636 3 6375 0.0551 6089 0.0527 9.077 0.693
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 11 628 10 629 11 0.00019 11 0.00019 -0.052 0.693
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 58 581 57 582 61 0.00106 62 0.00107 -0.478 0.693
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 161 478 160 479 200 0.00375 210 0.00394 -2.539 0.693
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 638 1 637 2 5984 0.0517 5988 0.0518 -0.272 0.693
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 611 28 610 29 4101 0.0414 4143 0.0418 -1.891 0.693
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 278 361 277 362 400 0.00807 382 0.00771 3.399 0.693
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 196 443 195 444 245 0.00388 243 0.00386 0.379 0.693
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 175 464 174 465 211 0.00335 216 0.00343 -1.175 0.693
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 316 323 315 324 485 0.0105 493 0.0107 -1.470 0.693
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 639 0 638 1 8634 0.0996 9122 0.105 -15.479 0.693
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 5 634 4 635 5 0.000115 4 9.23e-05 1.931 0.693
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 35 604 34 605 36 0.000882 35 0.000858 0.659 0.693
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 511 128 510 129 1835 0.0212 2097 0.0242 -16.474 0.693
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 266 373 266 373 363 0.00785 364 0.00788 -0.264 0.649
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 236 403 236 403 361 0.00624 422 0.0073 -10.379 0.648
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 147 492 147 492 180 0.00311 177 0.00306 0.738 0.642
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 121 518 121 518 140 0.00222 138 0.00219 0.524 0.638
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 520 119 520 119 1299 0.0169 1588 0.0206 -22.067 0.637
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 72 567 72 567 79 0.00148 76 0.00143 1.203 0.625
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 51 588 51 588 57 0.00107 54 0.00101 1.434 0.614
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 282 357 283 356 450 0.00908 409 0.00826 7.553 0.607
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 269 370 270 369 378 0.00545 472 0.00681 -13.781 0.607
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 480 159 481 158 940 0.0108 1003 0.0116 -5.727 0.595
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 27 612 27 612 29 0.000711 27 0.000662 1.548 0.588
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 76 563 77 562 79 0.00216 87 0.00238 -3.783 0.565
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 565 74 566 73 2240 0.0355 2148 0.0341 6.581 0.563
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 66 573 67 572 73 0.00158 78 0.00169 -2.233 0.557
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 15 624 15 624 15 0.000303 15 0.000303 -0.045 0.557
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 64 575 65 574 70 0.00121 74 0.00128 -1.649 0.556
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 148 491 150 489 182 0.00262 178 0.00257 0.907 0.547
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 583 56 584 55 3615 0.0573 3320 0.0527 17.297 0.547
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 12 627 12 627 12 0.000277 14 0.000323 -2.182 0.542
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 592 47 593 46 2033 0.0293 2098 0.0303 -4.664 0.536
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 9 630 9 630 9 0.000221 9 0.000221 -0.049 0.522
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 37 602 38 601 40 0.000865 38 0.000822 1.219 0.521
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 554 85 556 83 2536 0.0256 2908 0.0294 -18.626 0.514
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 8 631 8 631 8 0.000173 8 0.000173 -0.053 0.513
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 6 633 6 633 6 0.000147 6 0.000147 -0.057 0.489
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 522 117 525 114 1788 0.0206 1691 0.0195 6.647 0.487
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 530 109 533 106 1792 0.0284 1682 0.0267 8.911 0.482
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 584 55 586 53 1806 0.0208 2134 0.0246 -20.426 0.480
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 5 634 5 634 6 0.000147 5 0.000123 1.783 0.472
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 544 95 547 92 1289 0.0186 1355 0.0195 -5.813 0.471
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 20 619 21 618 20 0.000404 22 0.000444 -1.636 0.471
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 20 619 21 618 20 0.00049 22 0.000539 -1.798 0.471
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 336 303 341 298 545 0.00786 589 0.0085 -5.817 0.459
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 415 224 420 219 738 0.0117 785 0.0125 -5.669 0.450
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 70 569 73 566 83 0.00179 84 0.00182 -0.462 0.448
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 206 433 211 428 277 0.00479 290 0.00502 -2.701 0.447
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 351 288 357 282 594 0.00771 660 0.00857 -7.800 0.426
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 486 153 491 148 1390 0.02 1714 0.0247 -25.150 0.425
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 3 636 3 636 3 9.08e-05 3 9.09e-05 -0.069 0.421
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 502 137 507 132 1099 0.0143 1111 0.0144 -1.165 0.416
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 553 86 557 82 1356 0.0215 1439 0.0228 -7.434 0.415
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 193 446 199 440 245 0.00424 270 0.00467 -5.331 0.409
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 119 520 124 515 133 0.00192 151 0.00218 -4.676 0.407
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 446 193 452 187 911 0.0144 1079 0.0171 -17.187 0.407
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 319 320 326 313 469 0.00676 503 0.00725 -4.868 0.396
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 299 340 306 333 417 0.00781 462 0.00866 -7.641 0.396
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 298 341 305 334 446 0.00643 443 0.00639 0.397 0.396
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 288 351 295 344 397 0.00572 466 0.00672 -10.195 0.395
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 531 108 536 103 1303 0.0169 1336 0.0173 -2.815 0.394
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 263 376 270 369 481 0.00832 489 0.00846 -1.320 0.393
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 139 500 145 494 162 0.00257 180 0.00286 -4.498 0.384
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 430 209 437 202 707 0.0112 843 0.0134 -15.709 0.380
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 456 183 463 176 1418 0.0225 1713 0.0272 -24.062 0.370
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 308 331 316 323 534 0.0077 567 0.00818 -4.460 0.367
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 556 83 561 78 2287 0.033 2586 0.0373 -19.064 0.366
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 397 242 405 234 952 0.0096 1123 0.0113 -13.643 0.359
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 231 408 239 400 317 0.00503 332 0.00527 -2.788 0.358
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 142 497 149 490 175 0.00303 195 0.00338 -5.013 0.352
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 64 575 69 570 70 0.00172 75 0.00184 -2.421 0.344
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 6 633 7 632 6 0.000138 7 0.000162 -1.566 0.342
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 294 345 303 336 459 0.00662 510 0.00736 -7.224 0.339
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 356 283 365 274 796 0.0103 936 0.0122 -13.879 0.337
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 245 394 254 385 320 0.00461 355 0.00512 -5.938 0.333
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 224 415 233 406 288 0.00415 295 0.00425 -1.339 0.328
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 527 112 534 105 2089 0.0241 2452 0.0283 -21.132 0.322
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 350 289 360 279 524 0.00604 572 0.0066 -5.749 0.312
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 378 261 388 251 716 0.0103 736 0.0106 -2.411 0.308
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 474 165 483 156 1499 0.0173 1946 0.0225 -29.072 0.300
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 590 49 595 44 1816 0.0209 1933 0.0223 -7.704 0.300
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 520 119 528 111 1941 0.0224 2372 0.0274 -25.475 0.296
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 573 66 579 60 2743 0.0316 3061 0.0353 -16.663 0.295
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 143 496 152 487 165 0.00238 198 0.00286 -7.467 0.292
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 270 369 281 358 462 0.00599 540 0.00701 -10.159 0.286
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 95 544 103 536 104 0.00165 111 0.00176 -2.244 0.279
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 538 101 546 93 1303 0.015 1376 0.0159 -5.689 0.276
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 8 631 10 629 8 0.000196 10 0.000245 -2.655 0.273
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 543 96 551 88 1376 0.0178 1453 0.0189 -6.203 0.270
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 23 616 27 612 23 0.000564 27 0.000662 -3.213 0.269
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 600 39 605 34 2194 0.0285 2536 0.0329 -20.824 0.268
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 33 606 38 601 33 0.000713 38 0.000822 -3.180 0.264
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 159 480 170 469 198 0.00285 219 0.00316 -4.537 0.250
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 422 217 434 205 747 0.0118 824 0.0131 -9.026 0.248
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 39 600 45 594 41 0.000827 45 0.000909 -2.269 0.242
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 27 612 32 607 27 0.000623 33 0.000762 -4.216 0.238
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 519 120 529 110 1053 0.0152 1209 0.0174 -14.392 0.238
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 62 577 70 569 69 0.00139 82 0.00166 -5.413 0.228
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 250 389 264 375 335 0.00628 385 0.00722 -9.276 0.218
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 23 616 28 611 23 0.00053 28 0.000646 -3.818 0.218
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 601 38 607 32 2166 0.0187 2365 0.0205 -10.214 0.217
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 485 154 497 142 1583 0.0228 1989 0.0287 -29.306 0.216
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 174 465 187 452 227 0.00327 244 0.00352 -3.492 0.213
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 453 186 466 173 1388 0.02 1688 0.0243 -23.467 0.213
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 209 430 223 416 286 0.00453 318 0.00505 -6.015 0.208
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 592 47 599 40 2264 0.0228 2676 0.027 -21.458 0.207
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 13 626 17 622 13 0.000281 17 0.000368 -3.799 0.196
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 230 409 245 394 304 0.0057 311 0.00583 -1.488 0.195
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 19 620 24 615 20 0.000404 24 0.000485 -3.095 0.194
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 486 153 499 140 1705 0.0221 2103 0.0273 -26.494 0.193
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 295 344 311 328 478 0.0103 584 0.0126 -17.163 0.187
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 282 357 298 341 441 0.00381 454 0.00393 -1.544 0.186
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 466 173 480 159 1187 0.0171 1394 0.0201 -17.795 0.186
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 356 283 372 267 578 0.00916 613 0.00973 -4.775 0.184
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 262 377 278 361 386 0.00556 452 0.00652 -9.901 0.184
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 449 190 464 175 871 0.0126 1293 0.0186 -37.536 0.175
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 140 499 154 485 166 0.00239 201 0.0029 -7.859 0.174
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 337 302 354 285 553 0.00797 566 0.00816 -1.795 0.170
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 499 140 513 126 1814 0.0209 2132 0.0246 -19.815 0.163
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 45 594 54 585 49 0.00113 54 0.00125 -2.760 0.160
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 446 193 462 177 805 0.00928 955 0.011 -13.869 0.159
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 35 604 43 596 37 0.00096 54 0.0014 -9.857 0.158
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 329 310 347 292 547 0.00867 569 0.00903 -3.135 0.155
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 565 74 576 63 1940 0.028 2123 0.0306 -12.861 0.150
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 75 564 87 552 78 0.00191 97 0.00238 -8.002 0.148
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 391 248 409 230 584 0.00842 702 0.0101 -14.217 0.146
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 89 550 102 537 102 0.00235 119 0.00275 -6.283 0.146
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 392 247 410 229 823 0.00949 944 0.0109 -11.265 0.146
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 409 230 427 212 694 0.01 748 0.0108 -6.344 0.141
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 168 471 185 454 187 0.00296 227 0.0036 -8.864 0.139
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 426 213 444 195 1037 0.0149 1255 0.0181 -19.717 0.136
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 79 560 92 547 88 0.00165 98 0.00184 -3.684 0.134
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 1 638 2 637 1 2.45e-05 2 4.9e-05 -3.004 0.133
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 549 90 562 77 2142 0.0247 2398 0.0277 -15.094 0.131
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 446 193 464 175 1180 0.0136 1419 0.0164 -18.169 0.128
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 154 485 172 467 199 0.00287 228 0.00329 -6.126 0.118
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 24 615 32 607 25 0.000504 33 0.000666 -5.249 0.116
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 2 637 4 635 2 4.9e-05 4 9.81e-05 -4.188 0.115
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 2 637 4 635 2 5.19e-05 4 0.000104 -4.306 0.115
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 54 585 66 573 56 0.00161 75 0.00216 -9.859 0.112
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 6 633 10 629 6 0.000138 10 0.000231 -5.107 0.109
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 42 597 53 586 48 0.00104 54 0.00117 -3.201 0.106
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 33 606 43 596 35 0.000706 46 0.000929 -6.107 0.101
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 122 517 140 499 146 0.00274 171 0.00321 -6.946 0.099
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 25 614 34 605 26 0.000525 35 0.000707 -5.731 0.095
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 433 206 454 185 1166 0.0168 1504 0.0217 -27.948 0.095
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 151 488 171 468 184 0.00345 240 0.0045 -13.107 0.092
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 19 620 27 612 20 0.000461 29 0.000669 -6.724 0.092
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 444 195 465 174 812 0.00936 921 0.0106 -10.277 0.091
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 592 47 603 36 2026 0.0234 2227 0.0257 -12.301 0.090
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 141 498 161 478 185 0.00293 205 0.00325 -4.683 0.087
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 190 449 212 427 237 0.00444 283 0.00531 -9.934 0.087
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 55 584 69 570 59 0.00119 71 0.00143 -5.369 0.081
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 420 219 443 196 942 0.0122 1230 0.016 -24.906 0.079
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 495 144 515 124 1887 0.0163 2279 0.0197 -20.397 0.077
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 16 623 24 615 16 0.000392 25 0.000613 -7.460 0.077
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 159 480 181 458 182 0.00289 225 0.00357 -9.567 0.075
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 356 283 381 258 572 0.00907 696 0.011 -15.739 0.073
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 408 231 433 206 1022 0.0162 1233 0.0196 -20.209 0.065
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 1 638 3 636 1 2.88e-05 3 8.65e-05 -5.232 0.064
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 59 580 75 564 62 0.00125 87 0.00176 -10.073 0.062
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 154 485 178 461 203 0.00351 253 0.00438 -10.958 0.057
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 100 539 121 518 110 0.00285 150 0.00389 -13.925 0.053
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 162 477 187 452 183 0.00264 227 0.00327 -9.292 0.053
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 374 265 402 237 740 0.0117 918 0.0146 -19.699 0.050
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 93 546 114 525 111 0.0016 146 0.00211 -9.207 0.048
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 6 633 12 627 6 0.000147 12 0.000294 -7.185 0.048
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 303 336 332 307 577 0.00915 797 0.0126 -26.074 0.048
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 208 431 236 403 310 0.00536 389 0.00673 -13.974 0.045
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 247 392 276 363 319 0.0046 361 0.00521 -7.058 0.045
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 179 460 206 433 236 0.0034 298 0.0043 -11.426 0.045
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 341 298 371 268 782 0.0124 976 0.0155 -20.829 0.041
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 204 435 233 406 294 0.00551 369 0.00692 -14.178 0.039
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 48 591 65 574 50 0.000865 71 0.00123 -8.674 0.039
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 388 251 418 221 657 0.0104 742 0.0118 -10.478 0.037
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 59 580 78 561 62 0.00125 86 0.00174 -9.728 0.036
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 405 234 435 204 900 0.013 1130 0.0163 -21.889 0.034
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 502 137 527 112 1457 0.0168 1559 0.018 -7.456 0.034
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 410 229 440 199 673 0.0097 802 0.0116 -14.554 0.034
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 175 464 204 435 243 0.0035 296 0.00427 -9.807 0.034
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 276 363 308 331 401 0.00867 573 0.0124 -28.065 0.032
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 121 518 147 492 133 0.00364 176 0.00482 -14.208 0.032
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 424 215 454 185 1140 0.0131 1419 0.0164 -21.197 0.031
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 144 495 172 467 198 0.00314 249 0.00395 -10.784 0.030
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 205 434 236 403 309 0.0049 426 0.00676 -18.914 0.030
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 235 404 267 372 297 0.00428 368 0.00531 -11.783 0.030
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 86 553 110 529 95 0.00178 137 0.00257 -12.992 0.026
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 440 199 471 168 1259 0.0254 1418 0.0286 -16.130 0.024
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 348 291 383 256 774 0.0134 1006 0.0174 -25.637 0.021
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 91 548 117 522 102 0.00147 149 0.00215 -12.225 0.020
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 217 422 252 387 338 0.00536 466 0.00739 -19.790 0.018
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 153 486 185 454 198 0.00285 264 0.00381 -12.912 0.018
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 443 196 476 163 1022 0.0147 1203 0.0174 -16.725 0.017
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 9 630 19 620 9 0.000195 20 0.000433 -9.566 0.017
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 449 190 482 157 972 0.0154 1170 0.0186 -19.459 0.016
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 127 512 158 481 166 0.00311 212 0.00398 -11.457 0.016
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 1 638 5 634 1 2.31e-05 5 0.000115 -7.216 0.016
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 183 456 220 419 248 0.00393 344 0.00546 -17.260 0.011
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 368 271 407 232 642 0.00925 751 0.0108 -12.710 0.011
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 13 626 26 613 13 0.000319 27 0.000662 -11.147 0.011
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 24 615 41 598 24 0.000415 46 0.000796 -11.275 0.011
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 24 615 41 598 25 0.000577 45 0.00104 -11.965 0.011
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 376 263 415 224 814 0.00939 1083 0.0125 -23.330 0.011
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 63 576 89 550 72 0.00104 103 0.00149 -9.702 0.010
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 95 544 126 513 118 0.00204 153 0.00265 -9.854 0.009
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 346 293 387 252 658 0.00948 892 0.0129 -25.002 0.009
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 57 582 83 556 68 0.00127 93 0.00174 -9.391 0.008
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 103 536 136 503 126 0.002 188 0.00298 -15.058 0.007
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 391 248 432 207 640 0.00922 773 0.0111 -15.276 0.007
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 60 579 87 552 63 0.00127 105 0.00212 -15.388 0.007
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 316 323 360 279 483 0.00696 598 0.00863 -14.993 0.006
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 2 637 9 630 2 4.61e-05 9 0.000208 -9.381 0.006
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 11 628 25 614 11 0.000222 25 0.000505 -10.516 0.005
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 306 333 351 288 440 0.00824 527 0.00988 -13.793 0.005
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 370 269 414 225 748 0.0108 1097 0.0158 -33.657 0.005
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 374 265 418 221 659 0.0095 781 0.0113 -13.948 0.005
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 65 574 95 544 70 0.00141 120 0.00242 -17.134 0.004
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 338 301 384 255 596 0.00945 947 0.015 -38.182 0.004
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 409 230 454 185 949 0.0137 1414 0.0204 -39.586 0.003
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 178 461 226 413 249 0.00502 381 0.00769 -25.451 0.002
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 321 318 373 266 609 0.0132 892 0.0193 -37.133 0.001
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 245 394 297 342 322 0.00511 408 0.00647 -14.217 0.001
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 12 627 31 608 13 0.000319 34 0.000834 -14.888 0.001
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 120 519 167 472 134 0.00212 187 0.00297 -12.912 0.001
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 82 557 124 515 96 0.00208 157 0.0034 -18.925 0.001
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 154 485 210 429 174 0.00251 275 0.00397 -19.339 0.000
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 144 495 199 440 158 0.00228 250 0.00361 -18.473 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 161 478 218 421 188 0.00325 306 0.0053 -23.473 0.000
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 172 467 231 408 205 0.00561 330 0.00904 -30.183 0.000
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 116 523 170 469 126 0.00272 193 0.00418 -18.759 0.000
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 14 625 39 600 15 0.000346 42 0.000969 -16.705 0.000
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 301 338 370 269 421 0.00607 581 0.00838 -21.133 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 13 626 40 599 14 0.000303 42 0.000909 -16.773 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 230 409 306 333 286 0.00495 411 0.00711 -21.485 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 160 479 259 380 214 0.0037 421 0.00729 -35.121 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 102 537 191 448 119 0.00206 256 0.00443 -29.765 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 142 497 248 391 184 0.00318 369 0.00639 -33.512 0.000
BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 0 639 0 639 0 0 0 0 NA 0.000
SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 0 639 3 636 0 0 3 6.92e-05 -7.003 0.000
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 0 639 1 638 0 0 1 2.88e-05 -4.586 0.000
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 0 639 6 633 0 0 6 0.00013 -9.544 0.000

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HOMER results

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