Human Analysis


Summary

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Job ID: FF:11862-125A8
Number of target experiments: 1
Number of target CAGE peaks: 1938
Number of target CAGE peak regions: 1226
Number of background CAGE peaks: random background
Number of background CAGE peak regions: 1226
TFBS profile type: JASPAR
JASPAR collection(s): CORE 
Taxonomic supergroup(s): vertebrates 
Matrix score threshold: 85%
CAGE peak flanking sequence size: 500 / 500
Results returned: All results sorted by Fisher score

Target Experiments


FF:11862-125A8 CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor1


Results

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Warning: The provided background set resulted in zero binding sites for one or more TFs. These cases are highlighted in red. In cases where there were also zero binding sites for the target set, the Z-score is undefined (NA). In cases where there were one or more binding sites in the target set, the Z-score is infinite (Inf). However, the result may or may not be considered significant. Results for which this was the case are marked with an asterisk (*).

TF JASPAR ID Class Family Tax group IC GC Content Target CAGE peak region hits Target CAGE peak region non-hits Background CAGE peak region hits Background CAGE peak region non-hits Target TFBS hits Target TFBS nucleotide rate Background TFBS hits Background TFBS nucleotide rate Z-score Fisher score
ETV6 MA0645.1 Tryptophan cluster factors Ets-related factors vertebrates 12.354 0.564 1097 129 945 281 2787 0.0205 2133 0.0157 44.957 37.093
FLI1 MA0475.2 Tryptophan cluster factors Ets-related factors vertebrates 13.279 0.533 992 234 825 401 1982 0.0146 1464 0.0108 42.892 32.515
ELK4 MA0076.2 Tryptophan cluster factors Ets-related factors vertebrates 13.085 0.630 1042 184 886 340 2487 0.0201 1850 0.015 49.314 32.476
ERG MA0474.2 Tryptophan cluster factors Ets-related factors vertebrates 11.781 0.514 1047 179 894 332 2322 0.0171 1686 0.0124 49.124 31.868
ETV4 MA0764.1 Tryptophan cluster factors Ets-related factors vertebrates 10.625 0.519 971 255 805 421 1930 0.0142 1437 0.0106 41.195 30.963
ETS1 MA0098.3 Tryptophan cluster factors Ets-related factors vertebrates 12.150 0.528 987 239 828 398 1978 0.0146 1464 0.0108 42.560 29.608
SPI1 MA0080.4 Tryptophan cluster factors Ets-related factors vertebrates 21.562 0.391 182 1044 75 1151 201 0.00207 78 0.000805 52.055 27.969
ETV1 MA0761.1 Tryptophan cluster factors Ets-related factors vertebrates 10.759 0.530 929 297 772 454 1798 0.0132 1361 0.01 37.503 26.346
ELK3 MA0759.1 Tryptophan cluster factors Ets-related factors vertebrates 11.791 0.539 746 480 577 649 1154 0.00849 864 0.00637 31.181 26.099
Gabpa MA0062.2 Tryptophan cluster factors Ets-related factors vertebrates 13.335 0.647 843 383 686 540 1559 0.0126 1201 0.00973 34.288 24.032
FEV MA0156.2 Tryptophan cluster factors Ets-related factors vertebrates 11.713 0.519 990 236 851 375 2036 0.015 1535 0.0113 40.514 23.701
IRF8 MA0652.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 22.505 0.465 73 1153 17 1209 77 0.000793 17 0.000175 54.377 21.408
ETV5 MA0765.1 Tryptophan cluster factors Ets-related factors vertebrates 9.461 0.569 1109 117 1007 219 3154 0.0232 2499 0.0184 41.631 20.554
ERF MA0760.1 Tryptophan cluster factors Ets-related factors vertebrates 12.896 0.540 573 653 427 799 792 0.00583 560 0.00413 30.966 20.532
SPIC MA0687.1 Tryptophan cluster factors Ets-related factors vertebrates 13.235 0.421 360 866 233 993 450 0.00464 277 0.00286 38.856 20.489
RELA MA0107.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 14.757 0.567 549 677 406 820 773 0.00569 523 0.00385 34.536 20.059
ETV2 MA0762.1 Tryptophan cluster factors Ets-related factors vertebrates 14.664 0.452 435 791 310 916 568 0.0046 378 0.00306 32.370 17.520
ELF5 MA0136.2 Tryptophan cluster factors Ets-related factors vertebrates 10.425 0.538 1153 73 1082 144 3699 0.0299 2781 0.0225 58.181 15.151
IRF2 MA0051.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 21.134 0.412 56 1170 16 1210 59 0.000782 16 0.000212 45.543 13.968
ETV3 MA0763.1 Tryptophan cluster factors Ets-related factors vertebrates 11.632 0.531 562 664 447 779 767 0.00565 618 0.00455 18.899 13.465
ZNF263 MA0528.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.073 0.597 911 315 804 422 2157 0.0333 1671 0.0259 54.973 13.428
ZNF740 MA0753.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 12.467 0.786 909 317 802 424 2307 0.017 2191 0.0161 7.739 13.393
ELF1 MA0473.2 Tryptophan cluster factors Ets-related factors vertebrates 16.243 0.536 291 935 198 1028 332 0.00293 230 0.00203 23.246 13.360
PRDM1 MA0508.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.223 0.380 435 791 328 898 555 0.00613 422 0.00466 25.032 13.208
STAT1::STAT2 MA0517.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 16.390 0.373 334 892 237 989 434 0.00479 279 0.00308 35.902 13.044
TFAP2C MA0524.2 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.460 0.738 1075 151 994 232 4490 0.0397 4110 0.0363 20.669 12.421
ELK1 MA0028.2 Tryptophan cluster factors Ets-related factors vertebrates 14.316 0.561 593 633 483 743 846 0.00623 693 0.00511 18.324 12.306
Creb5 MA0840.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 16.321 0.443 188 1038 115 1111 210 0.00185 128 0.00113 25.055 12.293
ELF4 MA0641.1 Tryptophan cluster factors Ets-related factors vertebrates 16.253 0.606 225 1001 146 1080 249 0.0022 165 0.00146 22.601 12.169
EHF MA0598.2 Tryptophan cluster factors Ets-related factors vertebrates 14.797 0.591 247 979 166 1060 276 0.00244 183 0.00162 23.763 11.796
TFAP2B MA0811.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.870 0.738 1087 139 1012 214 4884 0.0431 4467 0.0395 21.795 11.535
ATF7 MA0834.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 17.313 0.456 128 1098 70 1156 142 0.00146 74 0.000763 29.524 11.451
E2F4 MA0470.1 Fork head / winged helix factors E2F-related factors vertebrates 13.176 0.729 1043 183 962 264 5506 0.0446 5025 0.0407 22.715 11.195
IRF9 MA0653.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 24.834 0.425 37 1189 9 1217 40 0.000442 9 9.95e-05 39.947 10.966
NFATC1 MA0624.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.040 0.411 1140 86 1081 145 3881 0.0286 3432 0.0253 24.339 10.479
TFAP2C(var.3) MA0815.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.479 0.780 733 493 633 593 1339 0.0128 1258 0.012 8.143 10.475
IRF1 MA0050.2 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.950 0.357 190 1036 123 1103 211 0.00326 143 0.00221 26.008 10.388
IRF7 MA0772.1 Tryptophan cluster factors Interferon-regulatory factors vertebrates 17.627 0.419 184 1042 121 1105 209 0.00215 133 0.00137 24.606 9.553
SPIB MA0081.1 Tryptophan cluster factors Ets-related factors vertebrates 9.060 0.466 1214 12 1188 38 7773 0.04 6184 0.0319 54.085 8.925
Stat4 MA0518.1 STAT domain factors STAT factors vertebrates 13.473 0.446 817 409 729 497 1554 0.016 1280 0.0132 28.689 8.908
KLF16 MA0741.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.161 0.767 1040 186 970 256 4199 0.034 3898 0.0316 16.020 8.864
JDP2(var.2) MA0656.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 17.511 0.485 147 1079 93 1133 165 0.00146 98 0.000867 23.393 8.801
SP2 MA0516.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.721 0.768 1081 145 1018 208 5479 0.0605 4973 0.055 28.279 8.646
Bcl6 MA0463.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.663 0.433 364 862 286 940 444 0.00458 350 0.00361 18.745 8.464
EBF1 MA0154.3 Rel homology region (RHR) factors Early B-Cell Factor-related factors vertebrates 16.027 0.559 252 974 185 1041 281 0.0029 199 0.00205 21.697 8.321
RUNX3 MA0684.1 Runt domain factors Runt-related factors vertebrates 11.687 0.452 769 457 684 542 1242 0.00914 1056 0.00778 18.050 8.194
RUNX1 MA0002.2 Runt domain factors Runt-related factors vertebrates 10.401 0.502 1027 199 959 267 2469 0.02 2128 0.0172 24.555 8.191
Ascl2 MA0816.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 12.850 0.580 813 413 731 495 1411 0.0104 1274 0.00939 12.067 7.956
JUN(var.2) MA0489.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.941 0.426 546 680 463 763 819 0.00844 656 0.00677 23.776 7.873
MSC MA0665.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.856 0.452 323 903 252 974 375 0.00276 291 0.00214 15.515 7.776
EGR1 MA0162.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.889 0.785 1152 74 1107 119 7812 0.0805 7214 0.0744 27.025 7.677
HSF4 MA0771.1 Heat shock factors HSF factors vertebrates 13.629 0.398 329 897 259 967 383 0.00366 289 0.00277 19.882 7.515
Crem MA0609.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.449 0.416 282 944 216 1010 349 0.00257 243 0.00179 21.450 7.515
Atf1 MA0604.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.519 0.476 725 501 644 582 1235 0.00727 1019 0.00601 19.087 7.473
SP4 MA0685.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 19.967 0.677 405 821 333 893 622 0.00778 535 0.0067 15.448 7.034
ELF3 MA0640.1 Tryptophan cluster factors Ets-related factors vertebrates 17.342 0.584 165 1061 115 1111 172 0.00165 122 0.00117 16.269 7.001
MZF1(var.2) MA0057.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.400 0.588 1155 71 1114 112 4736 0.0349 4052 0.0299 34.267 6.887
GMEB2 MA0862.1 SAND domain factors GMEB vertebrates 9.886 0.392 407 819 336 890 554 0.00326 420 0.00248 18.438 6.865
TFAP2A(var.2) MA0810.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 10.759 0.764 1144 82 1101 125 8109 0.0716 7570 0.0669 21.880 6.805
HOXA5 MA0158.1 Homeo domain factors HOX-related factors vertebrates 8.759 0.315 1155 71 1115 111 5425 0.0319 5933 0.035 -19.211 6.654
TFAP2B(var.3) MA0813.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.355 0.726 706 520 632 594 1225 0.0117 1158 0.0111 7.003 6.482
Nfe2l2 MA0150.2 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.876 0.496 89 1137 54 1172 92 0.00102 65 0.000718 12.920 6.418
NFATC3 MA0625.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 8.847 0.381 1049 177 994 232 2690 0.0198 2484 0.0183 13.017 6.375
KLF14 MA0740.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.072 0.661 590 636 517 709 1057 0.0109 905 0.00934 18.863 6.356
Myod1 MA0499.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.102 0.600 1142 84 1101 125 3926 0.0376 3566 0.0342 21.877 6.284
INSM1 MA0155.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 14.862 0.667 699 527 628 598 1175 0.0104 1014 0.00897 17.465 6.087
SP3 MA0746.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 10.325 0.709 1122 104 1080 146 5735 0.0464 5240 0.0425 22.909 5.789
Myog MA0500.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 13.109 0.621 1180 46 1151 75 4668 0.0378 4314 0.035 17.955 5.428
MYBL1 MA0776.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 15.281 0.526 81 1145 51 1175 83 0.000733 53 0.000469 14.225 5.379
JDP2 MA0655.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 15.102 0.355 380 846 321 905 482 0.00319 400 0.00265 12.239 5.349
HSF2 MA0770.1 Heat shock factors HSF factors vertebrates 17.218 0.359 162 1064 122 1104 174 0.00166 126 0.00121 15.365 4.981
NFE2 MA0841.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 16.895 0.417 267 959 218 1008 306 0.00248 252 0.00204 11.224 4.900
NFAT5 MA0606.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 10.151 0.333 1110 116 1072 154 4269 0.0314 3969 0.0292 15.064 4.776
JUNB MA0490.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 13.910 0.457 796 430 738 488 1479 0.012 1332 0.0108 13.294 4.747
STAT1 MA0137.3 STAT domain factors STAT factors vertebrates 14.582 0.415 829 397 772 454 1577 0.0128 1332 0.0108 22.244 4.739
TFCP2 MA0145.3 Grainyhead domain factors CP2-related factors vertebrates 11.701 0.441 378 848 324 902 458 0.00337 392 0.00289 10.478 4.718
BATF3 MA0835.1 Basic leucine zipper factors (bZIP) B-ATF-related factors vertebrates 23.217 0.484 15 1211 4 1222 15 0.000155 4 4.13e-05 20.494 4.669
Myb MA0100.2 Tryptophan cluster factors Myb/SANT domain factors vertebrates 13.365 0.452 967 259 917 309 2253 0.0166 1903 0.014 25.391 4.659
FOSL1 MA0477.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.281 0.477 770 456 713 513 1332 0.0108 1243 0.0101 8.285 4.571
GLIS2 MA0736.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 16.871 0.758 287 939 239 987 391 0.00403 314 0.00324 16.201 4.570
EN2 MA0642.1 Homeo domain factors NK-related factors vertebrates 8.619 0.377 1081 145 1041 185 3052 0.0225 3069 0.0226 -1.167 4.561
RUNX2 MA0511.2 Runt domain factors Runt-related factors vertebrates 11.551 0.475 893 333 840 386 1610 0.0107 1419 0.00941 15.153 4.555
FOXO4 MA0848.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.660 0.295 1091 135 1054 172 4390 0.0226 4685 0.0242 -11.730 4.272
REL MA0101.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 10.515 0.559 903 323 853 373 1693 0.0125 1468 0.0108 18.532 4.264
NFATC2 MA0152.1 Rel homology region (RHR) factors NFAT-related factors vertebrates 9.859 0.346 1068 158 1029 197 3101 0.016 2897 0.0149 9.946 4.231
Stat6 MA0520.1 STAT domain factors STAT factors vertebrates 14.063 0.406 544 682 490 736 834 0.00921 678 0.00749 23.169 4.194
FOS::JUN MA0099.2 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Fos-related factors::Jun-related factors vertebrates 9.193 0.405 1145 81 1116 110 4366 0.0225 4402 0.0227 -1.638 4.056
MAF::NFE2 MA0501.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Maf-related factors::Jun-related factors vertebrates 17.621 0.429 88 1138 62 1164 90 0.000994 72 0.000796 8.166 4.050
SPDEF MA0686.1 Tryptophan cluster factors Ets-related factors vertebrates 14.474 0.536 462 764 411 815 592 0.00479 542 0.00439 7.049 4.047
EGR4 MA0733.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.890 0.635 256 970 214 1012 293 0.00345 266 0.00314 6.554 4.036
FOXL1 MA0033.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 10.626 0.221 1136 90 1106 120 5852 0.0302 6549 0.0338 -23.398 4.013
SCRT1 MA0743.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.728 0.573 101 1125 74 1152 106 0.00117 79 0.000873 11.714 3.884
Atf3 MA0605.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 11.483 0.498 837 389 789 437 1516 0.00893 1355 0.00799 12.301 3.803
KLF5 MA0599.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.860 0.792 1211 15 1197 29 14083 0.104 12625 0.093 42.677 3.756
MYF6 MA0667.1 Basic helix-loop-helix factors (bHLH) MyoD / ASC-related factors vertebrates 14.583 0.392 316 910 273 953 377 0.00277 324 0.00239 9.250 3.750
ZIC1 MA0696.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 18.774 0.762 373 853 328 898 472 0.00486 446 0.0046 4.526 3.705
FOSL2 MA0478.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 14.013 0.477 818 408 771 455 1504 0.0122 1424 0.0115 6.934 3.655
NR2C2 MA0504.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 16.248 0.589 511 715 463 763 663 0.00732 618 0.00683 6.926 3.642
BATF::JUN MA0462.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) B-ATF-related factors::Jun-related factors vertebrates 13.645 0.367 756 470 709 517 1439 0.0117 1277 0.0104 14.979 3.538
STAT3 MA0144.2 STAT domain factors STAT factors vertebrates 13.049 0.436 1134 92 1107 119 4011 0.0325 3785 0.0307 12.151 3.491
Sox2 MA0143.3 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.532 0.436 1115 111 1086 140 3391 0.02 3434 0.0202 -2.272 3.475
SNAI2 MA0745.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.486 0.570 1221 5 1212 14 6991 0.0463 7255 0.0481 -9.799 3.465
TFAP2A(var.3) MA0872.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 14.096 0.784 633 593 586 640 1086 0.0104 1077 0.0103 0.866 3.455
SP8 MA0747.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.140 0.714 988 238 950 276 2986 0.0264 2816 0.0249 11.037 3.406
TEF MA0843.1 TEA domain factors TEF-1-related factors vertebrates 14.579 0.317 289 937 251 975 372 0.00329 312 0.00276 11.706 3.334
DBP MA0639.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.741 0.344 399 827 357 869 573 0.00506 489 0.00432 13.095 3.311
ZBTB7C MA0695.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 10.450 0.618 695 531 650 576 1130 0.00998 1084 0.00958 4.738 3.295
Bach1::Mafk MA0591.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) Jun-related factors::Maf-related factors vertebrates 18.324 0.548 86 1140 64 1162 88 0.000972 86 0.00095 0.784 3.264
TP53 MA0106.3 p53 domain factors p53-related factors vertebrates 20.661 0.551 15 1211 6 1220 16 0.000212 7 9.28e-05 14.369 3.256
Klf1 MA0493.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.595 0.665 1032 194 998 228 2970 0.024 2725 0.0221 15.549 3.252
BHLHE41 MA0636.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 15.486 0.585 285 941 248 978 357 0.00263 318 0.00234 6.853 3.245
MSX1 MA0666.1 Homeo domain factors NK-related factors vertebrates 8.661 0.279 1042 184 1009 217 3238 0.0191 3533 0.0208 -14.358 3.213
HLF MA0043.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.834 0.365 589 637 545 681 935 0.00826 864 0.00764 8.285 3.200
Klf4 MA0039.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 12.618 0.771 1159 67 1137 89 7533 0.0554 6943 0.0512 22.693 3.194
BARHL2 MA0635.1 Homeo domain factors NK-related factors vertebrates 8.495 0.352 1122 104 1096 130 5848 0.043 6389 0.0471 -22.184 3.152
Stat5a::Stat5b MA0519.1 STAT domain factors::STAT domain factors STAT factors::STAT factors vertebrates 13.332 0.399 1097 129 1069 157 3307 0.0268 2986 0.0242 19.520 3.110
CEBPG MA0838.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.660 0.434 371 855 332 894 461 0.00339 414 0.00305 7.238 3.105
Znf423 MA0116.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.925 0.679 513 713 471 755 720 0.00795 637 0.00704 12.668 3.088
Foxj2 MA0614.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.782 0.247 963 263 927 299 2922 0.0172 3292 0.0194 -18.582 3.073
SRF MA0083.3 MADS box factors Responders to external signals (SRF/RLM1) vertebrates 20.984 0.467 13 1213 5 1221 13 0.000153 5 5.89e-05 14.239 3.047
SCRT2 MA0744.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.902 0.568 142 1084 116 1110 151 0.00144 123 0.00118 9.050 2.998
ZIC4 MA0751.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.598 0.697 547 679 506 720 843 0.00931 821 0.00907 2.866 2.969
Gata4 MA0482.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.320 0.388 969 257 935 291 2398 0.0194 2230 0.0181 11.734 2.904
NHLH1 MA0048.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.190 0.691 840 386 802 424 1542 0.0114 1454 0.0107 7.204 2.881
Ar MA0007.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.664 0.539 48 1178 33 1193 48 0.000601 34 0.000426 9.851 2.872
MAFG MA0659.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 16.353 0.463 11 1215 4 1222 11 0.00017 15 0.000232 -4.777 2.836
Pparg::Rxra MA0065.2 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 11.663 0.547 391 835 355 871 505 0.00558 446 0.00493 10.750 2.777
CEBPE MA0837.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 11.682 0.433 743 483 705 521 1355 0.00997 1261 0.00929 8.284 2.744
FOS MA0476.1 Basic leucine zipper factors (bZIP) Fos-related factors vertebrates 13.637 0.423 646 580 608 618 1102 0.00892 1009 0.00818 9.631 2.696
PROX1 MA0794.1 Homeo domain factors HD-PROS factors vertebrates 16.936 0.455 135 1091 112 1114 144 0.00127 134 0.00118 2.939 2.661
Pitx1 MA0682.1 Homeo domain factors Paired-related HD factors vertebrates 8.584 0.371 1047 179 1020 206 2909 0.0171 3261 0.0192 -17.767 2.598
Tcf12 MA0521.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 13.159 0.597 1107 119 1084 142 3302 0.0267 3066 0.0249 14.112 2.593
JUND(var.2) MA0492.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.021 0.393 520 706 484 742 710 0.00784 672 0.00743 5.586 2.586
Gmeb1 MA0615.1 SAND domain factors GMEB vertebrates 8.363 0.521 330 896 298 928 411 0.00514 354 0.00443 12.425 2.581
Nr2e1 MA0676.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 11.374 0.291 805 421 770 456 1601 0.0106 1553 0.0103 3.544 2.577
TBP MA0108.2 TATA-binding proteins TBP-related factors vertebrates 10.086 0.377 554 672 518 708 834 0.00921 828 0.00915 0.691 2.563
RORA(var.2) MA0072.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 17.425 0.369 111 1115 92 1134 117 0.00121 104 0.00107 4.717 2.370
PLAG1 MA0163.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 19.352 0.798 211 1015 186 1040 247 0.00255 211 0.00218 9.213 2.363
EGR3 MA0732.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 18.153 0.721 322 904 293 933 428 0.00473 409 0.00452 3.557 2.343
MEIS2 MA0774.1 Homeo domain factors TALE-type homeo domain factors vertebrates 10.958 0.494 989 237 962 264 2298 0.0135 2096 0.0124 12.412 2.339
Rarb(var.2) MA0858.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.795 0.471 15 1211 8 1218 15 0.000188 8 0.0001 10.144 2.264
RXRA::VDR MA0074.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2)::Thyroid hormone receptor-related factors (NR1) vertebrates 20.451 0.527 27 1199 18 1208 28 0.000309 18 0.000199 9.077 2.170
CEBPB MA0466.2 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 12.768 0.434 757 469 727 499 1406 0.0103 1332 0.00981 6.316 2.159
FOXD2 MA0847.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.622 0.249 1179 47 1166 60 8044 0.0414 8856 0.0457 -23.623 2.140
ESR2 MA0258.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.119 0.581 550 676 520 706 764 0.00844 714 0.00789 7.160 2.130
PAX4 MA0068.2 Paired box factors Paired plus homeo domain vertebrates 9.469 0.309 561 665 531 695 919 0.00541 917 0.00541 0.093 2.126
Mecom MA0029.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 17.909 0.280 72 1154 58 1168 77 0.000793 63 0.00065 6.551 2.115
ZBTB7B MA0694.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.963 0.628 482 744 453 773 642 0.00567 628 0.00555 1.844 2.102
NRF1 MA0506.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.300 0.810 918 308 892 334 4236 0.0343 4041 0.0328 10.115 2.076
FOXP3 MA0850.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 8.594 0.299 1163 63 1149 77 6817 0.0351 7130 0.0368 -10.225 2.049
FOXO6 MA0849.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.992 0.294 1045 181 1024 202 3511 0.0181 3870 0.02 -15.590 2.018
MYBL2 MA0777.1 Tryptophan cluster factors Myb/SANT domain factors vertebrates 16.774 0.467 14 1212 8 1218 14 0.000155 8 8.84e-05 8.155 1.952
DUXA MA0884.1 Homeo domain factors Paired-related HD factors vertebrates 12.572 0.301 304 922 281 945 376 0.0036 372 0.00356 0.669 1.906
MAFF MA0495.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.864 0.411 217 1009 197 1029 249 0.0033 235 0.00312 3.804 1.878
KLF13 MA0657.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 20.517 0.517 28 1198 20 1206 30 0.000397 21 0.000279 8.283 1.872
Tcf21 MA0832.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 18.108 0.461 60 1166 49 1177 60 0.000618 49 0.000505 5.832 1.810
ATF4 MA0833.1 Basic leucine zipper factors (bZIP) ATF-4-related factors vertebrates 15.609 0.443 169 1057 152 1074 189 0.00181 168 0.00161 5.784 1.778
HNF4G MA0484.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.379 0.492 765 461 741 485 1296 0.0143 1228 0.0136 7.418 1.772
E2F3 MA0469.2 Fork head / winged helix factors E2F-related factors vertebrates 21.784 0.442 7 1219 3 1223 7 9.27e-05 3 3.98e-05 9.717 1.764
Foxo1 MA0480.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.240 0.365 776 450 753 473 1506 0.0122 1505 0.0122 -0.052 1.717
BSX MA0876.1 Homeo domain factors NK-related factors vertebrates 8.513 0.311 1099 127 1084 142 4794 0.0282 5192 0.0306 -16.076 1.699
FOXD1 MA0031.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.926 0.275 736 490 713 513 1466 0.00863 1541 0.00908 -5.546 1.698
JUND MA0491.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 14.728 0.436 692 534 669 557 1185 0.00959 1162 0.00942 2.125 1.684
E2F6 MA0471.1 Fork head / winged helix factors E2F-related factors vertebrates 13.338 0.693 1175 51 1165 61 6665 0.054 6119 0.0496 23.457 1.650
SOX21 MA0866.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 23.365 0.300 28 1198 21 1205 28 0.000309 21 0.000232 5.867 1.643
HSF1 MA0486.2 Heat shock factors HSF factors vertebrates 18.738 0.366 93 1133 81 1145 103 0.000986 84 0.000805 7.424 1.642
NFYB MA0502.1 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 14.488 0.501 309 917 290 936 400 0.00442 446 0.00493 -8.543 1.616
SMAD2::SMAD3::SMAD4 MA0513.1 SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors::SMAD/NF-1 DNA-binding domain factors SMAD factors::SMAD factors::SMAD factors vertebrates 13.704 0.556 448 778 427 799 592 0.00566 568 0.00544 3.544 1.611
GATA1::TAL1 MA0140.2 Other C4 zinc finger-type factors::Basic helix-loop-helix factors (bHLH) GATA-type zinc fingers::Tal-related factors vertebrates 14.296 0.444 168 1058 153 1073 186 0.00246 168 0.00223 5.829 1.605
NFKB1 MA0105.4 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 20.522 0.671 123 1103 110 1116 135 0.00129 116 0.00111 6.308 1.588
JUN MA0488.1 Basic leucine zipper factors (bZIP) Jun-related factors vertebrates 15.128 0.380 554 672 533 693 743 0.00711 790 0.00757 -6.159 1.570
ZIC3 MA0697.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.252 0.750 182 1044 167 1059 221 0.00244 193 0.00213 7.745 1.564
CENPB MA0637.1 Psq-type HTH domain - vertebrates 13.999 0.562 257 969 240 986 302 0.00333 280 0.00309 5.022 1.557
EN1 MA0027.2 Homeo domain factors NK-related factors vertebrates 9.349 0.249 1023 203 1007 219 3449 0.0203 3848 0.0227 -18.580 1.555
SP1 MA0079.3 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 13.323 0.810 1190 36 1182 44 10580 0.0857 9568 0.0775 35.357 1.546
FOXG1 MA0613.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.341 0.225 848 378 829 397 2170 0.0128 2493 0.0147 -18.574 1.527
CEBPD MA0836.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.212 0.426 650 576 630 596 1058 0.00779 1020 0.00752 3.665 1.509
GCM1 MA0646.1 GCM domain factors GCM factors vertebrates 13.024 0.596 620 606 600 626 930 0.00753 956 0.00775 -2.910 1.508
RARA::RXRA MA0159.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 16.004 0.535 63 1163 54 1172 64 0.000801 55 0.000689 4.955 1.495
ZNF410 MA0752.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 24.530 0.381 5 1221 2 1224 6 7.51e-05 2 2.51e-05 11.564 1.486
FIGLA MA0820.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.386 0.566 1113 113 1101 125 3071 0.0226 3239 0.0239 -9.635 1.485
GATA2 MA0036.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.428 0.361 490 736 471 755 708 0.0073 708 0.0073 -0.108 1.477
TCF4 MA0830.1 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.920 0.625 1196 30 1189 37 5254 0.0387 5296 0.039 -2.106 1.475
T MA0009.2 T-Box factors Brachyury-related factors vertebrates 18.965 0.510 11 1215 7 1219 11 0.00013 7 8.25e-05 5.986 1.429
CREB3 MA0638.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 15.483 0.552 93 1133 83 1143 98 0.00101 97 0.001 0.328 1.424
RREB1 MA0073.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 22.278 0.623 144 1082 132 1094 166 0.00244 147 0.00217 6.947 1.423
RARA(var.2) MA0730.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 22.768 0.535 19 1207 14 1212 20 0.00025 14 0.000175 6.560 1.419
GBX1 MA0889.1 Homeo domain factors HOX-related factors vertebrates 10.843 0.319 721 505 703 523 1265 0.00931 1401 0.0103 -11.671 1.413
FOXI1 MA0042.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.617 0.289 920 306 904 322 2335 0.012 2527 0.013 -10.309 1.411
CREB1 MA0018.2 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 10.139 0.523 709 517 691 535 1105 0.00651 1030 0.00607 6.527 1.411
*SOX4 MA0867.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.967 0.335 2 1224 0 1226 2 2.36e-05 0 0 NA 1.387
Sox11 MA0869.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 27.229 0.305 6 1220 3 1223 6 6.62e-05 3 3.32e-05 6.623 1.372
DLX6 MA0882.1 Homeo domain factors NK-related factors vertebrates 8.327 0.229 1053 173 1041 185 4350 0.0256 4920 0.029 -23.524 1.329
TAL1::TCF3 MA0091.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 14.070 0.453 301 925 287 939 369 0.00326 334 0.00295 6.567 1.312
FOXO3 MA0157.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.427 0.265 682 544 666 560 1291 0.0076 1370 0.00808 -6.172 1.304
HINFP MA0131.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 13.024 0.717 650 576 634 592 1284 0.0113 1252 0.0111 3.017 1.302
EGR2 MA0472.2 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 15.289 0.730 551 675 536 690 962 0.00779 1002 0.00812 -4.320 1.257
NR4A2 MA0160.1 Nuclear receptors with C4 zinc fingers NGFI-B-related receptors (NR4) vertebrates 10.165 0.491 1050 176 1039 187 2576 0.0152 2581 0.0152 -0.434 1.256
NR3C2 MA0727.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 18.985 0.510 62 1164 55 1171 63 0.000788 55 0.000689 4.399 1.255
Npas2 MA0626.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.517 0.589 830 396 816 410 1450 0.0107 1549 0.0114 -8.130 1.244
MEOX1 MA0661.1 Homeo domain factors HOX-related factors vertebrates 9.622 0.316 826 400 812 414 1722 0.0127 1849 0.0136 -9.545 1.243
NFYA MA0060.2 Heteromeric CCAAT-binding factors Heteromeric CCAAT-binding factors vertebrates 16.655 0.516 121 1105 112 1114 144 0.00191 185 0.00245 -12.866 1.235
Hand1::Tcf3 MA0092.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) Tal-related factors::E2A-related factors vertebrates 10.144 0.507 964 262 952 274 2192 0.0161 2101 0.0155 6.169 1.219
FOXC2 MA0846.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.607 0.229 731 495 717 509 1678 0.0148 2080 0.0184 -30.971 1.215
CEBPA MA0102.3 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 13.338 0.344 867 359 854 372 1954 0.0158 1922 0.0156 2.284 1.210
CDX2 MA0465.1 Homeo domain factors HOX-related factors vertebrates 13.813 0.281 687 539 673 553 1296 0.0105 1416 0.0115 -10.766 1.208
FOXF2 MA0030.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.824 0.334 133 1093 124 1102 143 0.00147 133 0.00137 3.189 1.207
Mlxip MA0622.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.531 0.625 564 662 550 676 795 0.00468 876 0.00516 -7.850 1.207
ZBED1 MA0749.1 C2H2 zinc finger factors BED zinc finger factors vertebrates 19.052 0.485 9 1217 6 1220 9 8.61e-05 7 6.71e-05 2.662 1.194
TBX1 MA0805.1 T-Box factors TBX1-related factors vertebrates 12.823 0.498 892 334 880 346 1676 0.00987 1780 0.0105 -7.134 1.172
Spz1 MA0111.1 Basic helix-loop-helix factors (bHLH) - vertebrates 11.907 0.538 507 719 494 732 657 0.00532 639 0.00518 2.274 1.168
Dlx2 MA0885.1 Homeo domain factors NK-related factors vertebrates 9.033 0.215 1080 146 1071 155 4767 0.0281 5372 0.0317 -23.934 1.167
MAFK MA0496.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 13.869 0.395 573 653 560 666 860 0.0095 884 0.00977 -3.264 1.160
ZEB1 MA0103.2 Homeo domain factors HD-ZF factors vertebrates 13.264 0.621 1065 161 1056 170 2642 0.0175 2720 0.018 -4.692 1.145
GRHL1 MA0647.1 Grainyhead domain factors Grainyhead-related factors vertebrates 14.286 0.390 128 1098 120 1106 139 0.00123 132 0.00117 2.057 1.141
Sox6 MA0515.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.201 0.401 990 236 980 246 2514 0.0185 2466 0.0182 2.916 1.128
Bhlha15 MA0607.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.820 0.455 937 289 927 299 1945 0.0115 1995 0.0118 -3.319 1.093
Myc MA0147.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.032 0.584 932 294 922 304 1796 0.0132 1953 0.0144 -11.459 1.090
NR3C1 MA0113.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 19.181 0.483 57 1169 52 1174 58 0.000726 53 0.000664 2.784 1.057
Rxra MA0512.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.648 0.503 60 1166 55 1171 61 0.000629 64 0.00066 -1.451 1.046
MGA MA0801.1 T-Box factors TBX6-related factors vertebrates 10.832 0.509 1132 94 1126 100 3488 0.0205 3487 0.0206 -0.129 1.038
CDX1 MA0878.1 Homeo domain factors HOX-related factors vertebrates 9.270 0.234 907 319 898 328 2862 0.019 3329 0.0221 -24.726 1.030
EWSR1-FLI1 MA0149.1 Tryptophan cluster factors Ets-related factors vertebrates 32.871 0.554 19 1207 16 1210 21 0.000278 20 0.000265 0.902 1.002
OTX1 MA0711.1 Homeo domain factors Paired-related HD factors vertebrates 9.437 0.416 1063 163 1057 169 3391 0.02 3789 0.0223 -18.671 0.957
Crx MA0467.1 Homeo domain factors Paired-related HD factors vertebrates 12.929 0.404 586 640 578 648 847 0.00686 852 0.00691 -0.676 0.945
Twist2 MA0633.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.928 0.423 505 721 498 728 708 0.00521 769 0.00567 -7.069 0.910
Nkx2-5(var.2) MA0503.1 Homeo domain factors NK-related factors vertebrates 12.615 0.534 1073 153 1068 158 2657 0.0215 2793 0.0226 -8.815 0.906
Msx3 MA0709.1 Homeo domain factors NK-related factors vertebrates 9.864 0.246 946 280 940 286 2584 0.0152 2999 0.0177 -21.780 0.903
Vdr MA0693.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 21.487 0.479 52 1174 49 1177 54 0.000636 52 0.000613 1.062 0.869
ZBTB33 MA0527.1 C2H2 zinc finger factors Other factors with up to three adjacent zinc fingers vertebrates 14.336 0.609 167 1059 163 1063 187 0.00206 183 0.00202 1.082 0.845
Gfi1b MA0483.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.514 0.415 823 403 818 408 1584 0.0128 1823 0.0148 -18.845 0.840
ARNT::HIF1A MA0259.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.740 0.657 1034 192 1030 196 3143 0.0185 3315 0.0195 -8.702 0.835
TFAP4 MA0691.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.151 0.444 494 732 489 737 661 0.00487 648 0.00477 1.528 0.833
Nobox MA0125.1 Homeo domain factors Paired-related HD factors vertebrates 9.573 0.260 721 505 716 510 1494 0.0088 1624 0.00957 -9.286 0.833
Gata1 MA0035.3 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.597 0.352 603 623 598 628 1010 0.00818 1010 0.00819 -0.114 0.831
Arid3a MA0151.1 ARID domain factors ARID-related factors vertebrates 9.896 0.062 930 296 926 300 3060 0.0135 3703 0.0164 -26.243 0.812
USF2 MA0526.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.559 0.555 835 391 831 395 1487 0.012 1600 0.013 -9.568 0.802
Tcf7 MA0769.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 16.918 0.356 135 1091 132 1094 145 0.00128 138 0.00122 2.010 0.802
Mafb MA0117.2 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 11.336 0.444 530 696 526 700 755 0.00667 774 0.00684 -2.478 0.796
PKNOX1 MA0782.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.435 0.506 62 1164 60 1166 64 0.000565 61 0.000539 1.284 0.770
Ahr::Arnt MA0006.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) PAS domain factors::PAS domain factors vertebrates 9.532 0.715 1156 70 1154 72 4292 0.019 4498 0.0199 -7.771 0.764
MSX2 MA0708.1 Homeo domain factors NK-related factors vertebrates 9.959 0.264 830 396 827 399 1767 0.0104 1963 0.0116 -12.713 0.764
TBX5 MA0807.1 T-Box factors TBX2-related factors vertebrates 8.477 0.507 1154 72 1152 74 3831 0.0226 4025 0.0237 -8.940 0.764
E2F1 MA0024.3 Fork head / winged helix factors E2F-related factors vertebrates 13.048 0.553 118 1108 116 1110 129 0.00114 128 0.00113 0.253 0.749
HNF1A MA0046.2 Homeo domain factors POU domain factors vertebrates 15.880 0.226 169 1057 167 1059 195 0.00215 224 0.00248 -7.579 0.741
Lhx8 MA0705.1 Homeo domain factors HD-LIM factors vertebrates 8.840 0.303 996 230 994 232 2512 0.0148 2743 0.0162 -12.729 0.735
Nr2e3 MA0164.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 12.028 0.373 286 940 284 942 354 0.00182 337 0.00174 2.390 0.732
GLIS3 MA0737.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 21.032 0.585 26 1200 25 1201 26 0.000268 26 0.000268 -0.046 0.693
HIC2 MA0738.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 8.457 0.634 1224 2 1223 3 10655 0.0706 10955 0.0726 -9.264 0.693
OTX2 MA0712.1 Homeo domain factors Paired-related HD factors vertebrates 9.434 0.355 1055 171 1054 172 3892 0.0229 4727 0.0279 -35.028 0.693
NKX2-8 MA0673.1 Homeo domain factors NK-related factors vertebrates 9.033 0.458 1226 0 1225 1 9953 0.0659 10179 0.0675 -7.282 0.693
TBX19 MA0804.1 T-Box factors Brachyury-related factors vertebrates 17.480 0.448 4 1222 3 1223 4 5.89e-05 3 4.42e-05 2.508 0.693
BARX1 MA0875.1 Homeo domain factors NK-related factors vertebrates 8.892 0.306 1077 149 1076 150 4626 0.0272 5475 0.0323 -33.196 0.693
BHLHE40 MA0464.2 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.695 0.599 620 606 619 607 953 0.00701 977 0.0072 -2.543 0.693
MEIS3 MA0775.1 Homeo domain factors TALE-type homeo domain factors vertebrates 9.016 0.490 1199 27 1198 28 5479 0.0323 5455 0.0322 0.712 0.693
Gfi1 MA0038.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 9.470 0.391 885 341 884 342 1894 0.0139 1888 0.0139 0.293 0.693
RHOXF1 MA0719.1 Homeo domain factors Paired-related HD factors vertebrates 8.182 0.438 1226 0 1225 1 16601 0.0978 17140 0.101 -12.681 0.693
ZNF354C MA0130.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.958 0.615 1225 1 1224 2 11653 0.0515 12000 0.0531 -8.257 0.693
PPARG MA0066.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 20.365 0.523 2 1224 1 1225 2 2.94e-05 1 1.47e-05 4.353 0.693
SOX8 MA0868.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 28.805 0.342 2 1224 1 1225 2 2.36e-05 1 1.18e-05 3.869 0.693
TCF7L2 MA0523.1 Basic helix-loop-helix factors (bHLH) TCF-7-related factors vertebrates 13.486 0.398 620 606 620 606 1027 0.0106 997 0.0103 3.444 0.661
NKX6-1 MA0674.1 Homeo domain factors NK-related factors vertebrates 9.183 0.199 987 239 987 239 3301 0.0194 3615 0.0213 -15.104 0.653
NRL MA0842.1 Basic leucine zipper factors (bZIP) Maf-related factors vertebrates 8.257 0.452 1027 199 1027 199 2595 0.021 2578 0.0209 0.943 0.650
TBR1 MA0802.1 T-Box factors TBrain-related factors vertebrates 12.472 0.439 580 646 581 645 812 0.00598 837 0.00617 -2.840 0.631
Dux MA0611.1 Homeo domain factors Paired-related HD factors vertebrates 11.804 0.338 478 748 479 747 665 0.00392 746 0.0044 -8.489 0.629
HOXC10 MA0905.1 Homeo domain factors HOX-related factors vertebrates 11.056 0.327 790 436 791 435 1775 0.0131 2141 0.0158 -25.356 0.628
MNT MA0825.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.166 0.600 806 420 807 419 1323 0.00974 1428 0.0105 -8.957 0.628
RXRG MA0856.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 22.332 0.505 73 1153 73 1153 75 0.000773 87 0.000897 -4.864 0.627
PITX3 MA0714.1 Homeo domain factors Paired-related HD factors vertebrates 8.973 0.406 971 255 972 254 2379 0.0158 2743 0.0182 -21.199 0.617
Alx4 MA0853.1 Homeo domain factors Paired-related HD factors vertebrates 13.490 0.348 43 1183 43 1183 43 0.000538 44 0.000551 -0.668 0.609
E2F8 MA0865.1 Fork head / winged helix factors E2F-related factors vertebrates 20.970 0.542 35 1191 35 1191 35 0.000309 36 0.000318 -0.623 0.601
XBP1 MA0844.1 Basic leucine zipper factors (bZIP) XBP-1-related factors vertebrates 15.475 0.537 104 1122 105 1121 108 0.00111 142 0.00146 -10.735 0.584
Sox1 MA0870.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 20.927 0.295 14 1212 14 1212 14 0.000155 15 0.000166 -1.048 0.553
FOXH1 MA0479.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.762 0.401 714 512 718 508 1214 0.00983 1263 0.0102 -4.721 0.543
HNF1B MA0153.2 Homeo domain factors POU domain factors vertebrates 16.242 0.207 111 1115 113 1113 122 0.00117 134 0.00128 -3.793 0.539
FOXC1 MA0032.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 11.875 0.201 805 421 809 417 2185 0.0177 2798 0.0227 -39.045 0.537
DMRT3 MA0610.1 DM-type intertwined zinc finger factors DMRT vertebrates 11.236 0.344 375 851 379 847 495 0.00401 556 0.00451 -8.682 0.533
Sox17 MA0078.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.502 0.384 885 341 889 337 1836 0.0122 1965 0.013 -8.925 0.529
NOTO MA0710.1 Homeo domain factors NK-related factors vertebrates 9.584 0.280 1042 184 1045 181 3876 0.0285 4307 0.0317 -21.315 0.528
Hoxd8 MA0910.1 Homeo domain factors HOX-related factors vertebrates 12.824 0.247 37 1189 38 1188 40 0.000501 38 0.000476 1.291 0.523
Pou5f1::Sox2 MA0142.1 Homeo domain factors::High-mobility group (HMG) domain factors POU domain factors::SOX-related factors vertebrates 14.808 0.308 81 1145 83 1143 90 0.000994 87 0.000962 1.194 0.518
CREB3L1 MA0839.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 17.262 0.560 32 1194 33 1193 32 0.00033 38 0.000392 -3.686 0.512
Shox2 MA0720.1 Homeo domain factors Paired-related HD factors vertebrates 9.249 0.214 1007 219 1011 215 3571 0.021 4198 0.0247 -27.897 0.504
Sox3 MA0514.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 13.042 0.401 1103 123 1106 120 3992 0.0294 3970 0.0293 0.908 0.500
PBX1 MA0070.1 Homeo domain factors TALE-type homeo domain factors vertebrates 14.641 0.310 109 1117 112 1114 117 0.00103 120 0.00106 -1.001 0.493
EMX2 MA0886.1 Homeo domain factors NK-related factors vertebrates 10.283 0.288 931 295 936 290 2502 0.0184 3000 0.0221 -29.244 0.491
Hes2 MA0616.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 8.309 0.532 475 751 481 745 624 0.00597 653 0.00625 -4.204 0.488
CLOCK MA0819.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.902 0.508 390 836 396 830 476 0.0035 575 0.00424 -13.162 0.480
Hmx1 MA0896.1 Homeo domain factors NK-related factors vertebrates 13.599 0.383 50 1176 52 1174 54 0.000676 53 0.000664 0.519 0.479
TFAP2B(var.2) MA0812.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 12.568 0.731 1079 147 1083 143 4053 0.0328 3984 0.0323 3.461 0.474
TP63 MA0525.2 p53 domain factors p53-related factors vertebrates 24.335 0.468 5 1221 5 1221 5 6.62e-05 5 6.63e-05 -0.062 0.473
GBX2 MA0890.1 Homeo domain factors HOX-related factors vertebrates 10.020 0.296 886 340 892 334 2116 0.0156 2471 0.0182 -22.948 0.471
Nkx3-1 MA0124.2 Homeo domain factors NK-related factors vertebrates 11.264 0.422 927 299 933 293 1874 0.0124 1931 0.0128 -4.056 0.463
HOXA10 MA0899.1 Homeo domain factors HOX-related factors vertebrates 9.141 0.292 750 476 757 469 1744 0.0141 1961 0.0159 -16.531 0.462
PKNOX2 MA0783.1 Homeo domain factors TALE-type homeo domain factors vertebrates 21.223 0.512 41 1185 43 1183 42 0.000371 45 0.000398 -1.594 0.461
TCF3 MA0522.2 Basic helix-loop-helix factors (bHLH) E2A-related factors vertebrates 11.473 0.608 1187 39 1189 37 4605 0.0339 4844 0.0357 -11.287 0.452
LIN54 MA0619.1 CRC domain - vertebrates 11.299 0.189 843 383 850 376 2248 0.0149 2535 0.0168 -17.398 0.452
GATA3 MA0037.2 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 13.796 0.265 971 255 977 249 2978 0.0175 3040 0.0179 -3.374 0.451
NFIC::TLX1 MA0119.1 SMAD/NF-1 DNA-binding domain factors::Homeo domain factors Nuclear factor 1::NK-related factors vertebrates 19.665 0.598 36 1190 38 1188 37 0.000381 38 0.000392 -0.652 0.449
LEF1 MA0768.1 High-mobility group (HMG) domain factors TCF-7-related factors vertebrates 17.861 0.425 62 1164 65 1161 63 0.000696 65 0.000718 -1.009 0.443
Nkx2-5 MA0063.1 Homeo domain factors NK-related factors vertebrates 8.270 0.218 1032 194 1038 188 4310 0.0222 4872 0.0251 -21.760 0.428
LBX1 MA0618.1 Homeo domain factors NK-related factors vertebrates 10.149 0.240 831 395 839 387 1996 0.0118 2171 0.0128 -10.827 0.428
FOXP2 MA0593.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.802 0.305 693 533 702 524 1317 0.0107 1482 0.012 -14.431 0.418
TGIF2 MA0797.1 Homeo domain factors TALE-type homeo domain factors vertebrates 18.378 0.488 72 1154 76 1150 77 0.00068 80 0.000707 -1.210 0.409
TEAD1 MA0090.2 TEA domain factors TEF-1-related factors vertebrates 9.508 0.424 1114 112 1119 107 3771 0.0278 3660 0.027 5.676 0.409
Klf12 MA0742.1 C2H2 zinc finger factors Three-zinc finger Krüppel-related factors vertebrates 16.798 0.612 418 808 427 799 634 0.007 613 0.00678 3.190 0.409
RXRB MA0855.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 23.110 0.505 40 1186 43 1183 40 0.000412 51 0.000526 -5.808 0.397
TFAP2A MA0003.3 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.101 0.742 1168 58 1172 54 8051 0.0652 7833 0.0635 8.122 0.377
E2F7 MA0758.1 Fork head / winged helix factors E2F-related factors vertebrates 24.200 0.458 8 1218 9 1217 8 8.24e-05 9 9.28e-05 -1.303 0.377
BCL6B MA0731.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 29.809 0.401 2 1224 2 1224 2 2.5e-05 2 2.51e-05 -0.092 0.374
Creb3l2 MA0608.1 Basic leucine zipper factors (bZIP) CREB-related factors vertebrates 12.997 0.624 726 500 737 489 1158 0.00767 1231 0.00816 -6.378 0.372
PDX1 MA0132.2 Homeo domain factors HOX-related factors vertebrates 9.911 0.238 888 338 898 328 2604 0.0153 3235 0.0191 -31.837 0.369
TEAD4 MA0809.1 TEA domain factors TEF-1-related factors vertebrates 9.386 0.418 1080 146 1087 139 3583 0.0264 3681 0.0271 -5.380 0.367
OLIG1 MA0826.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.663 0.334 272 954 282 944 330 0.00243 354 0.00261 -4.107 0.353
RFX3 MA0798.1 Fork head / winged helix factors RFX-related factors vertebrates 16.894 0.507 83 1143 89 1137 93 0.0011 94 0.00111 -0.466 0.343
NKX3-2 MA0122.2 Homeo domain factors NK-related factors vertebrates 10.208 0.421 982 244 992 234 2220 0.0147 2334 0.0155 -7.285 0.339
Foxk1 MA0852.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 15.268 0.300 90 1136 97 1129 102 0.00128 107 0.00134 -2.049 0.317
PRRX1 MA0716.1 Homeo domain factors Paired-related HD factors vertebrates 8.226 0.213 948 278 960 266 3069 0.0181 3671 0.0216 -28.579 0.306
SMAD3 MA0795.1 SMAD/NF-1 DNA-binding domain factors SMAD factors vertebrates 15.611 0.453 127 1099 136 1090 136 0.001 143 0.00105 -1.903 0.297
FOXA1 MA0148.3 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.765 0.334 748 478 763 463 1580 0.0174 1833 0.0203 -23.287 0.292
MTF1 MA0863.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 20.407 0.620 9 1217 11 1215 9 9.27e-05 11 0.000113 -2.308 0.289
Hoxa9 MA0594.1 Homeo domain factors HOX-related factors vertebrates 13.740 0.326 267 959 280 946 335 0.00271 360 0.00292 -4.447 0.286
YY2 MA0748.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 11.703 0.548 319 907 333 893 379 0.00307 411 0.00333 -5.318 0.283
HEY1 MA0823.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 12.269 0.677 542 684 558 668 815 0.006 905 0.00667 -9.591 0.281
TFAP2C(var.2) MA0814.1 Basic helix-span-helix factors (bHSH) AP-2 vertebrates 11.387 0.715 1132 94 1140 86 4959 0.0402 4989 0.0404 -1.687 0.278
Lhx3 MA0135.1 Homeo domain factors HD-LIM factors vertebrates 16.354 0.131 164 1062 175 1051 178 0.0017 210 0.00201 -8.029 0.276
Rfx1 MA0509.1 Fork head / winged helix factors RFX-related factors vertebrates 15.161 0.557 198 1028 210 1016 223 0.0023 231 0.00238 -2.039 0.275
Esrra MA0592.2 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 17.764 0.409 186 1040 198 1028 206 0.00167 220 0.00178 -3.193 0.268
Hoxa11 MA0911.1 Homeo domain factors HOX-related factors vertebrates 11.443 0.370 329 897 344 882 401 0.00354 444 0.00393 -7.162 0.267
Arx MA0874.1 Homeo domain factors Paired-related HD factors vertebrates 14.279 0.327 32 1194 37 1189 33 0.000413 37 0.000463 -2.756 0.264
BHLHE23 MA0817.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.991 0.338 176 1050 188 1038 208 0.00184 226 0.002 -4.213 0.262
ZBTB18 MA0698.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 15.425 0.459 492 734 509 717 649 0.00621 716 0.00686 -9.160 0.261
HMBOX1 MA0895.1 Homeo domain factors POU domain factors vertebrates 9.583 0.347 721 505 738 488 1390 0.0102 1403 0.0103 -1.230 0.261
ID4 MA0824.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 11.591 0.601 1102 124 1112 114 3232 0.0238 3418 0.0252 -10.381 0.257
NFIL3 MA0025.1 Basic leucine zipper factors (bZIP) C/EBP-related vertebrates 14.139 0.265 274 952 289 937 351 0.00284 360 0.00292 -1.648 0.250
MNX1 MA0707.1 Homeo domain factors HOX-related factors vertebrates 8.729 0.228 886 340 902 324 2674 0.0197 3277 0.0241 -33.895 0.248
Nr2f6 MA0677.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 18.175 0.483 52 1174 59 1167 53 0.000546 69 0.000712 -7.254 0.247
SRY MA0084.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.193 0.238 822 404 839 387 2176 0.0144 2573 0.0171 -23.832 0.246
FOXP1 MA0481.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.261 0.301 493 733 511 715 773 0.00853 947 0.0105 -22.131 0.245
TBX2 MA0688.1 T-Box factors TBX2-related factors vertebrates 10.262 0.450 660 566 679 547 1003 0.00812 1095 0.00888 -9.376 0.234
TBX20 MA0689.1 T-Box factors TBX1-related factors vertebrates 13.845 0.429 316 910 333 893 390 0.00316 391 0.00317 -0.244 0.229
Hoxc9 MA0485.1 Homeo domain factors HOX-related factors vertebrates 13.615 0.344 218 1008 233 993 264 0.00253 289 0.00277 -5.379 0.226
Rarg(var.2) MA0860.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 25.520 0.537 10 1216 13 1213 10 0.000125 13 0.000163 -3.478 0.225
Hnf4a MA0114.3 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 21.667 0.508 23 1203 28 1198 23 0.000271 28 0.00033 -3.824 0.221
CTCF MA0139.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 17.205 0.645 123 1103 135 1091 135 0.00189 145 0.00203 -3.686 0.218
Pou2f3 MA0627.1 Homeo domain factors POU domain factors vertebrates 15.067 0.318 83 1143 93 1133 88 0.00104 100 0.00118 -4.854 0.217
RFX5 MA0510.2 Fork head / winged helix factors RFX-related factors vertebrates 20.460 0.515 22 1204 27 1199 23 0.000271 28 0.00033 -3.824 0.215
TFEB MA0692.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.336 0.533 757 469 777 449 1257 0.00925 1339 0.00987 -7.243 0.211
E2F2 MA0864.1 Fork head / winged helix factors E2F-related factors vertebrates 23.763 0.395 2 1224 3 1223 2 2.36e-05 3 3.54e-05 -2.388 0.207
Arid3b MA0601.1 ARID domain factors ARID-related factors vertebrates 10.307 0.153 613 613 634 592 1255 0.0102 1578 0.0128 -27.269 0.207
Alx1 MA0854.1 Homeo domain factors Paired-related HD factors vertebrates 13.599 0.333 61 1165 70 1156 61 0.000763 72 0.000902 -5.395 0.204
REST MA0138.2 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 23.134 0.596 4 1222 6 1220 4 6.18e-05 6 9.28e-05 -3.796 0.188
Pax6 MA0069.1 Paired box factors Paired plus homeo domain vertebrates 13.798 0.432 33 1193 40 1186 34 0.00035 41 0.000423 -4.135 0.187
GSC MA0648.1 Homeo domain factors Paired-related HD factors vertebrates 9.643 0.433 829 397 850 376 1662 0.0122 2242 0.0165 -39.199 0.186
Id2 MA0617.1 Basic helix-loop-helix factors (bHLH) HLH domain only vertebrates 12.659 0.623 546 680 569 657 787 0.00463 837 0.00493 -4.989 0.181
TGIF1 MA0796.1 Homeo domain factors TALE-type homeo domain factors vertebrates 22.281 0.543 16 1210 21 1205 16 0.000141 21 0.000186 -3.826 0.175
NEUROD2 MA0668.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 10.701 0.465 1025 201 1042 184 2386 0.0176 2577 0.019 -12.177 0.173
NKX2-3 MA0672.1 Homeo domain factors NK-related factors vertebrates 10.899 0.485 1144 82 1155 71 3706 0.0273 3918 0.0289 -11.073 0.172
mix-a MA0621.1 Homeo domain factors Paired-related HD factors vertebrates 12.512 0.199 276 950 296 930 350 0.00283 421 0.00341 -11.568 0.172
MLXIPL MA0664.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 12.730 0.511 296 930 317 909 363 0.00267 416 0.00307 -8.300 0.165
Hoxd9 MA0913.1 Homeo domain factors HOX-related factors vertebrates 9.118 0.300 821 405 844 382 2289 0.0168 2740 0.0202 -27.687 0.162
HOXD12 MA0873.1 Homeo domain factors HOX-related factors vertebrates 14.187 0.355 246 980 266 960 303 0.00245 330 0.00267 -5.004 0.161
Atoh1 MA0461.2 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.381 0.409 607 619 632 594 955 0.00703 1004 0.0074 -5.015 0.159
ESR1 MA0112.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 22.540 0.570 9 1217 13 1213 9 0.000113 13 0.000163 -4.621 0.153
TBX15 MA0803.1 T-Box factors TBX1-related factors vertebrates 13.306 0.505 812 414 836 390 1442 0.00849 1575 0.00928 -9.639 0.152
RORA MA0071.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 13.190 0.424 461 765 486 740 617 0.00454 668 0.00492 -6.343 0.151
NEUROG2 MA0669.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 14.502 0.395 283 943 305 921 370 0.00272 366 0.0027 0.591 0.149
Arnt MA0004.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 10.992 0.642 621 605 647 579 1037 0.00458 1106 0.00489 -5.183 0.148
Hmx2 MA0897.1 Homeo domain factors NK-related factors vertebrates 14.390 0.335 24 1202 31 1195 25 0.000313 31 0.000388 -4.487 0.148
RFX2 MA0600.2 Fork head / winged helix factors RFX-related factors vertebrates 20.246 0.536 31 1195 39 1187 32 0.000377 40 0.000472 -5.104 0.148
Phox2b MA0681.1 Homeo domain factors Paired-related HD factors vertebrates 13.021 0.174 401 825 426 800 627 0.00508 746 0.00605 -14.586 0.143
MEF2C MA0497.1 MADS box factors Regulators of differentiation vertebrates 14.023 0.282 583 643 610 616 1012 0.0112 1431 0.0158 -43.375 0.138
SREBF1 MA0595.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.517 0.569 789 437 816 410 1399 0.0103 1476 0.0109 -6.500 0.125
RFX4 MA0799.1 Fork head / winged helix factors RFX-related factors vertebrates 15.596 0.481 132 1094 150 1076 149 0.00175 161 0.0019 -3.847 0.122
GCM2 MA0767.1 GCM domain factors GCM factors vertebrates 11.005 0.594 813 413 840 386 1550 0.0114 1561 0.0115 -1.019 0.121
GATA5 MA0766.1 Other C4 zinc finger-type factors GATA-type zinc fingers vertebrates 8.347 0.307 1041 185 1061 165 3624 0.0213 4246 0.025 -27.525 0.120
Foxd3 MA0041.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.945 0.223 630 596 659 567 1309 0.0116 1762 0.0156 -37.814 0.119
OLIG3 MA0827.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 11.442 0.387 593 633 623 603 958 0.00705 1013 0.00746 -5.592 0.111
PAX1 MA0779.1 Paired box factors Paired domain only vertebrates 19.655 0.599 41 1185 52 1174 44 0.000551 52 0.000651 -4.621 0.108
NFKB2 MA0778.1 Rel homology region (RHR) factors NF-kappaB-related factors vertebrates 16.488 0.698 319 907 346 880 400 0.00383 482 0.00462 -13.579 0.107
MAX MA0058.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 11.435 0.606 787 439 816 410 1358 0.01 1508 0.0111 -12.409 0.107
Hoxb5 MA0904.1 Homeo domain factors HOX-related factors vertebrates 12.676 0.334 40 1186 51 1175 41 0.000483 54 0.000637 -7.122 0.105
BHLHE22 MA0818.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 13.037 0.384 291 935 318 908 370 0.00272 403 0.00297 -5.277 0.100
Hmx3 MA0898.1 Homeo domain factors NK-related factors vertebrates 13.950 0.330 20 1206 28 1198 20 0.00025 28 0.000351 -6.277 0.099
NFIA MA0670.1 SMAD/NF-1 DNA-binding domain factors Nuclear factor 1 vertebrates 12.177 0.500 401 825 431 795 495 0.00364 557 0.0041 -8.404 0.098
MAX::MYC MA0059.1 Basic helix-loop-helix factors (bHLH)::Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors::bHLH-ZIP factors vertebrates 14.237 0.602 216 1010 241 985 233 0.00189 269 0.00218 -7.350 0.093
Hoxd3 MA0912.1 Homeo domain factors HOX-related factors vertebrates 11.598 0.341 155 1071 177 1049 177 0.00208 207 0.00244 -8.415 0.091
HES5 MA0821.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 18.532 0.704 108 1118 127 1099 115 0.00102 162 0.00143 -12.851 0.089
LHX6 MA0658.1 Homeo domain factors HD-LIM factors vertebrates 10.963 0.288 555 671 588 638 910 0.0067 1070 0.00788 -15.633 0.088
HOXC12 MA0906.1 Homeo domain factors HOX-related factors vertebrates 14.403 0.356 276 950 304 922 338 0.00274 398 0.00323 -10.062 0.088
POU4F2 MA0683.1 Homeo domain factors POU domain factors vertebrates 20.936 0.268 13 1213 20 1206 13 0.000153 20 0.000236 -6.305 0.083
Lhx4 MA0704.1 Homeo domain factors HD-LIM factors vertebrates 8.328 0.194 965 261 992 234 3376 0.0199 4105 0.0242 -32.755 0.083
Hic1 MA0739.1 C2H2 zinc finger factors Factors with multiple dispersed zinc fingers vertebrates 9.519 0.606 1172 54 1185 41 4330 0.0287 4908 0.0325 -25.375 0.074
HEY2 MA0649.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 11.968 0.672 609 617 645 581 893 0.00657 1015 0.00748 -12.258 0.070
LHX2 MA0700.1 Homeo domain factors HD-LIM factors vertebrates 10.311 0.309 843 383 876 350 1807 0.0133 2212 0.0163 -27.600 0.069
POU4F3 MA0791.1 Homeo domain factors POU domain factors vertebrates 13.812 0.287 44 1182 58 1168 44 0.000518 63 0.000743 -9.622 0.067
VSX1 MA0725.1 Homeo domain factors Paired-related HD factors vertebrates 8.078 0.217 775 451 810 416 1966 0.0116 2515 0.0148 -31.331 0.066
MZF1 MA0056.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 8.586 0.725 1223 3 1225 1 13930 0.0615 12988 0.0574 20.544 0.064
NR2F1 MA0017.2 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 13.343 0.589 629 597 666 560 928 0.00888 1023 0.0098 -10.881 0.064
HOXC13 MA0907.1 Homeo domain factors HOX-related factors vertebrates 14.190 0.361 237 989 267 959 271 0.00219 312 0.00253 -7.773 0.063
Rhox11 MA0629.1 Homeo domain factors Paired-related HD factors vertebrates 12.000 0.431 133 1093 157 1069 145 0.00181 171 0.00214 -8.268 0.061
Esrrg MA0643.1 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 13.141 0.453 783 443 819 407 1363 0.01 1433 0.0106 -6.004 0.060
ESRRB MA0141.3 Nuclear receptors with C4 zinc fingers Steroid hormone receptors (NR3) vertebrates 16.338 0.420 244 982 275 951 279 0.00226 328 0.00266 -9.051 0.058
USF1 MA0093.2 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.398 0.578 810 416 846 380 1417 0.0115 1584 0.0128 -14.141 0.057
PHOX2A MA0713.1 Homeo domain factors Paired-related HD factors vertebrates 12.067 0.175 366 860 403 823 562 0.00455 693 0.00562 -16.639 0.050
OLIG2 MA0678.1 Basic helix-loop-helix factors (bHLH) Tal-related factors vertebrates 12.953 0.374 322 904 358 868 415 0.00305 497 0.00366 -11.727 0.049
ZBTB7A MA0750.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 12.788 0.684 348 878 385 841 422 0.00373 482 0.00426 -9.568 0.048
PAX9 MA0781.1 Paired box factors Paired domain only vertebrates 22.261 0.612 13 1213 22 1204 13 0.000163 22 0.000276 -7.954 0.045
TBX21 MA0690.1 T-Box factors TBrain-related factors vertebrates 13.531 0.425 437 789 477 749 550 0.00405 629 0.00463 -10.068 0.044
TEAD3 MA0808.1 TEA domain factors TEF-1-related factors vertebrates 11.506 0.415 1085 141 1110 116 3349 0.0197 3808 0.0224 -21.453 0.044
Foxa2 MA0047.2 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.268 0.315 547 679 589 637 927 0.00819 1091 0.00965 -17.398 0.042
VENTX MA0724.1 Homeo domain factors NK-related factors vertebrates 11.046 0.353 752 474 793 433 1608 0.0107 2035 0.0135 -28.720 0.040
CUX2 MA0755.1 Homeo domain factors HD-CUT factors vertebrates 11.691 0.277 228 998 262 964 266 0.00196 335 0.00247 -11.999 0.039
TP73 MA0861.1 p53 domain factors p53-related factors vertebrates 17.517 0.483 45 1181 62 1164 47 0.000623 64 0.000849 -9.065 0.038
EOMES MA0800.1 T-Box factors TBrain-related factors vertebrates 12.412 0.416 333 893 372 854 401 0.00384 464 0.00444 -10.650 0.038
SOX9 MA0077.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 9.079 0.358 609 617 653 573 1000 0.00662 1153 0.00765 -13.673 0.035
RAX MA0718.1 Homeo domain factors Paired-related HD factors vertebrates 9.540 0.256 814 412 855 371 2041 0.015 2589 0.0191 -34.541 0.035
DUX4 MA0468.1 Homeo domain factors Paired-related HD factors vertebrates 15.012 0.238 634 592 678 548 1171 0.00948 1463 0.0119 -25.594 0.035
MLX MA0663.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.721 0.547 222 1004 257 969 258 0.0019 317 0.00234 -10.553 0.034
Foxq1 MA0040.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 14.070 0.202 305 921 345 881 416 0.00337 508 0.00412 -13.643 0.031
PROP1 MA0715.1 Homeo domain factors Paired-related HD factors vertebrates 15.122 0.084 193 1033 227 999 231 0.00187 289 0.00234 -11.390 0.031
POU3F3 MA0788.1 Homeo domain factors POU domain factors vertebrates 13.499 0.222 224 1002 260 966 287 0.00275 376 0.0036 -16.650 0.031
POU2F2 MA0507.1 Homeo domain factors POU domain factors vertebrates 15.114 0.289 365 861 408 818 492 0.00471 633 0.00606 -20.357 0.028
POU3F4 MA0789.1 Homeo domain factors POU domain factors vertebrates 13.378 0.229 457 769 503 723 727 0.00482 903 0.00599 -17.714 0.026
GLIS1 MA0735.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 25.361 0.673 7 1219 15 1211 7 8.24e-05 15 0.000177 -8.307 0.026
Nr5a2 MA0505.1 Nuclear receptors with C4 zinc fingers FTZ-F1-related receptors (NR5) vertebrates 14.913 0.522 239 987 278 948 273 0.00301 324 0.00358 -11.067 0.024
PAX7 MA0680.1 Paired box factors Paired plus homeo domain vertebrates 16.430 0.154 109 1117 138 1088 119 0.000876 160 0.00118 -10.305 0.022
TFE3 MA0831.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 9.435 0.570 995 231 1032 194 2272 0.0167 2437 0.018 -10.826 0.022
ZNF143 MA0088.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 22.060 0.491 32 1194 49 1177 32 0.000377 61 0.000719 -14.898 0.021
HOXC11 MA0651.1 Homeo domain factors HOX-related factors vertebrates 12.647 0.358 364 862 410 816 494 0.004 586 0.00475 -12.718 0.021
SREBF2 MA0596.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.554 0.540 577 649 627 599 854 0.00629 929 0.00685 -7.909 0.020
Arntl MA0603.1 Basic helix-loop-helix factors (bHLH) PAS domain factors vertebrates 11.029 0.583 594 632 645 581 899 0.00662 968 0.00713 -7.142 0.018
Foxj3 MA0851.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 13.311 0.330 214 1012 254 972 253 0.00317 333 0.00417 -18.189 0.018
FOXB1 MA0845.1 Fork head / winged helix factors Forkhead box (FOX) factors vertebrates 12.241 0.200 499 727 550 676 937 0.00759 1241 0.0101 -28.877 0.017
HOXD13 MA0909.1 Homeo domain factors HOX-related factors vertebrates 12.209 0.267 780 446 831 395 1685 0.0124 2336 0.0172 -43.106 0.014
Rarb MA0857.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 26.391 0.422 6 1220 15 1211 6 7.07e-05 15 0.000177 -9.339 0.013
PAX5 MA0014.2 Paired box factors Paired domain only vertebrates 13.609 0.583 399 827 452 774 489 0.00684 641 0.00897 -26.393 0.011
RARA MA0729.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 28.136 0.482 4 1222 12 1214 4 5.3e-05 12 0.000159 -9.843 0.010
POU5F1B MA0792.1 Homeo domain factors POU domain factors vertebrates 10.558 0.254 604 622 661 565 1210 0.00802 1537 0.0102 -25.265 0.010
HESX1 MA0894.1 Homeo domain factors Paired-related HD factors vertebrates 10.744 0.273 723 503 780 446 1541 0.0113 1965 0.0145 -30.602 0.008
NR1H2::RXRA MA0115.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 27.878 0.445 1 1225 6 1220 1 1.25e-05 6 7.52e-05 -8.472 0.008
PAX3 MA0780.1 Paired box factors Paired plus homeo domain vertebrates 15.425 0.145 160 1066 202 1024 179 0.00132 246 0.00181 -13.575 0.007
HOXB13 MA0901.1 Homeo domain factors HOX-related factors vertebrates 12.254 0.281 682 544 741 485 1313 0.00966 1744 0.0129 -32.973 0.007
Six3 MA0631.1 Homeo domain factors HD-SINE factors vertebrates 15.078 0.407 22 1204 40 1186 23 0.000288 40 0.000501 -11.126 0.007
POU4F1 MA0790.1 Homeo domain factors POU domain factors vertebrates 13.126 0.257 105 1121 141 1085 130 0.00134 168 0.00173 -11.034 0.006
SREBF2(var.2) MA0828.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 15.418 0.490 337 889 393 833 412 0.00303 522 0.00385 -15.328 0.006
POU6F1 MA0628.1 Homeo domain factors POU domain factors vertebrates 10.097 0.209 302 924 357 869 415 0.00305 510 0.00376 -13.402 0.005
Mycn MA0104.3 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 13.008 0.673 876 350 931 295 1652 0.00973 1893 0.0112 -15.879 0.005
Rarg MA0859.1 Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1) vertebrates 24.722 0.472 34 1192 57 1169 34 0.0004 57 0.000672 -12.231 0.005
HOXD11 MA0908.1 Homeo domain factors HOX-related factors vertebrates 12.370 0.321 421 805 482 744 634 0.00467 769 0.00567 -15.527 0.005
Srebf1(var.2) MA0829.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 14.940 0.492 317 909 374 852 380 0.0028 488 0.0036 -15.560 0.005
POU3F2 MA0787.1 Homeo domain factors POU domain factors vertebrates 13.773 0.240 251 975 304 922 328 0.0029 440 0.00389 -18.605 0.005
TBX4 MA0806.1 T-Box factors TBX2-related factors vertebrates 9.891 0.500 1140 86 1170 56 3808 0.0224 4148 0.0245 -15.303 0.004
VSX2 MA0726.1 Homeo domain factors Paired-related HD factors vertebrates 9.179 0.207 684 542 750 476 1434 0.00844 1895 0.0112 -30.238 0.003
HES7 MA0822.1 Basic helix-loop-helix factors (bHLH) Hairy-related factors vertebrates 19.784 0.730 60 1166 92 1134 62 0.000548 111 0.000981 -16.162 0.003
ISX MA0654.1 Homeo domain factors Paired-related HD factors vertebrates 10.591 0.200 826 400 888 338 2022 0.0119 2467 0.0145 -25.664 0.003
POU6F2 MA0793.1 Homeo domain factors POU domain factors vertebrates 11.693 0.311 493 733 560 666 749 0.00551 956 0.00704 -21.342 0.003
Sox5 MA0087.1 High-mobility group (HMG) domain factors SOX-related factors vertebrates 10.831 0.199 676 550 743 483 1529 0.00788 1835 0.00946 -19.102 0.003
HOXA13 MA0650.1 Homeo domain factors HOX-related factors vertebrates 11.356 0.282 636 590 706 520 1118 0.00823 1485 0.0109 -30.398 0.002
POU1F1 MA0784.1 Homeo domain factors POU domain factors vertebrates 14.958 0.281 98 1128 140 1086 110 0.00113 160 0.00165 -14.854 0.002
CUX1 MA0754.1 Homeo domain factors HD-CUT factors vertebrates 11.472 0.304 282 944 345 881 349 0.00257 472 0.00348 -18.004 0.002
Dmbx1 MA0883.1 Homeo domain factors Paired-related HD factors vertebrates 12.989 0.393 101 1125 144 1082 109 0.00136 153 0.00192 -14.736 0.001
Zfx MA0146.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 13.122 0.749 938 288 998 228 2967 0.0306 3120 0.0322 -10.635 0.001
TFEC MA0871.1 Basic helix-loop-helix factors (bHLH) bHLH-ZIP factors vertebrates 10.541 0.520 773 453 846 380 1304 0.0096 1516 0.0112 -17.438 0.001
POU3F1 MA0786.1 Homeo domain factors POU domain factors vertebrates 11.957 0.245 339 887 411 815 498 0.0044 682 0.00603 -24.568 0.001
Nr1h3::Rxra MA0494.1 Nuclear receptors with C4 zinc fingers::Nuclear receptors with C4 zinc fingers Thyroid hormone receptor-related factors (NR1)::RXR-related receptors (NR2) vertebrates 13.598 0.497 221 1005 288 938 243 0.0034 331 0.00463 -21.210 0.000
GLI2 MA0734.1 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.004 0.616 172 1054 234 992 187 0.00165 273 0.00241 -18.111 0.000
POU2F1 MA0785.1 Homeo domain factors POU domain factors vertebrates 12.044 0.265 374 852 454 772 565 0.00499 768 0.00679 -25.553 0.000
ONECUT1 MA0679.1 Homeo domain factors HD-CUT factors vertebrates 16.237 0.243 97 1129 153 1073 106 0.00109 177 0.00183 -20.038 0.000
ONECUT2 MA0756.1 Homeo domain factors HD-CUT factors vertebrates 15.765 0.228 83 1143 137 1089 87 0.000897 163 0.00168 -22.340 0.000
Nr2f6(var.2) MA0728.1 Nuclear receptors with C4 zinc fingers RXR-related receptors (NR2) vertebrates 25.042 0.463 25 1201 60 1166 25 0.000276 62 0.000685 -18.244 0.000
ONECUT3 MA0757.1 Homeo domain factors HD-CUT factors vertebrates 17.036 0.190 91 1135 150 1076 98 0.00101 182 0.00188 -23.369 0.000
MEF2A MA0052.3 MADS box factors Regulators of differentiation vertebrates 17.141 0.234 296 930 400 826 398 0.00352 651 0.00576 -34.528 0.000
YY1 MA0095.2 C2H2 zinc finger factors More than 3 adjacent zinc finger factors vertebrates 14.365 0.526 428 798 544 682 533 0.00471 690 0.0061 -20.857 0.000
Ddit3::Cebpa MA0019.1 Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP) C/EBP-related::C/EBP-related vertebrates 11.652 0.483 302 924 413 813 354 0.00313 543 0.0048 -28.240 0.000
MEF2B MA0660.1 MADS box factors Regulators of differentiation vertebrates 18.372 0.260 184 1042 286 940 209 0.00185 387 0.00342 -31.460 0.000
Arid5a MA0602.1 ARID domain factors ARID-related factors vertebrates 10.369 0.277 280 946 402 824 377 0.00388 646 0.00666 -39.817 0.000
MEF2D MA0773.1 MADS box factors Regulators of differentiation vertebrates 18.499 0.228 248 978 369 857 316 0.00279 575 0.00508 -37.584 0.000

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HOMER results

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